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Endoscopic features and prognoses of mantle cell lymphoma with gastrointestinal involvement

World Journal of Gastroenterology 2010年第37期16卷 4661-4669页

作者： Masaya Iwamuro Hiroyuki Okada Yoshiro Kawahara Katsuji Shinagawa toshiaki morito Tadashi Yoshino Kazuhide Yamamoto Department of Gastroenterology and Hepatology Okayama University Graduate School of Medicine Dentistry and Pharmaceutical Sciences Department of Hematology and Oncology Okayama University Graduate School of Medicine Dentistry and Pharmaceutical Sciences Department of Pathology Okayama University Graduate School of Medicine Dentistry and Pharmaceutical Sciences

AIM: To evaluate the endoscopic manifestations and prognoses of gastrointestinal (GI) mantle cell lymphoma (MCL). METHODS: A database search at the Department of Pathology of Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences revealed 57 MCL patients with GI involvement. Clinical records were available for 35 of the 57 patients from 21 institutions, and those 35 patients were enrolled in this study. We summarized the gross types of endoscopic features, event-free survival (EFS), and overall survival (OS) of those ***: Of the 35 patients, GI involvement in the esophagus, stomach, and duodenum was found in 2 (5.7%), 26 (74.3%), and 12 (34.3%) patients, respectively. Twenty-one of the 35 patients underwent colonoscopy; among them, GI involvement in the ileum, cecum, colon, and rectum was found in 10 (47.6%), 3 (14.3%), 12 (57.1%), and 10 (47.6%), respectively. Various lesions, such as superficial, protruded, fold thickening, or ulcerative, were found in the stomach, whereas multiple lymphomatous polyposis (MLP) was dominant from the duodenum to the rectum. Twelve patients were treated with a hyper-CVAD/MA regimen, and they had better OS (3-year rate, 88.3% vs 46.4%, P < 0.01) and better EFS (3-year rate, 66.7% vs 33.8%, P < 0.05) than the remaining 23 patients who were not treated with this regimen. CONCLUSION: MLP was a representative form of intestinal involvement, whereas a variety of lesions were found in the stomach. The hyper-CVAD/MA regimen may improve survival in these patients.

关键词： Chemotherapy Gastrointestinal lymphoma Mantle cell lymphoma Multiple lymphomatous polyposis Non-Hodgkin’s lymphoma

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Diagnostic role of 18F-fluorodeoxyglucose positron emission tomography for follicular lymphoma with gastrointestinal involvement

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World Journal of Gastroenterology 2012年第44期18卷 6427-6436页

作者： Masaya Iwamuro Hiroyuki Okada Katsuyoshi Takata Katsuji Shinagawa Shigeatsu Fujiki Junji Shiode Atsushi Imagawa Masashi Araki toshiaki morito Mamoru Nishimura Motowo Mizuno Tomoki Inaba Seiyu Suzuki Yoshinari Kawai Tadashi Yoshino Yoshiro Kawahara Akinobu Takaki Kazuhide Yamamoto Department of Gastroenterology and Hepatology Okayama University Graduate School of MedicineDentistryand Pharmaceutical SciencesOkayama 700-8558Japan Department of Endoscopy Okayama University HospitalOkayama 700-8558Japan Department of Pathology Okayama University Graduate School of MedicineDentistryand Pharmaceutical SciencesOkayama 700-8558Japan Department of Hematology and Oncology Okayama University Graduate School of MedicineDentistryand Pharmaceutical SciencesOkayama 700-8558Japan Department of Internal Medicine Tsuyama Central HospitalTsuyama 708-0841Japan Department of Internal Medicine Okayama Saiseikai General HospitalOkayama 700-8511Japan Department of Gastroenterology Mitoyo General HospitalKanonji 769-1695Japan Department of Internal Medicine Kagawa Rosai HospitalMarugame 763-8502Japan Department of Anatomic Pathology Kagawa Rosai HospitalMarugame 763-8502Japan Department of Internal Medicine Okayama Citizens' HospitalOkayama 700-8557Japan Department of Internal Medicine Hiroshima City HospitalHiroshima 730-8518Japan Department of Gastroenterology Kagawa Prefectural Central HospitalTakamatsu 760-8557Japan Department of Internal Medicine Sumitomo Besshi HospitalNiihama 792-8543Japan Department of Gastroenterology Onomichi Municipal HospitalOnomichi 722-8503Japan

AIM:To investigate the capacity for 18F-fluorodeoxyglucose(18F-FDG) positron emission tomography(PET) to evaluate patients with gastrointestinal lesions of follicular ***:This retrospective case series consisted of 41 patients with follicular lymphoma and gastrointestinal involvement who underwent 18F-FDG-PET and endoscopic evaluations at ten different institutions between November 1996 and October *** for endoscopic,radiological,and biological examinations performed were retrospectively reviewed from clinical records.A semi-quantitative analysis of 18F-FDG uptake was performed for each involved area by calculating the maximum standardized uptake value(SUVmax).Based on the positivity of 18F-FDG uptake in the gastrointestinal lesions analyzed,patients were subdivided into two *** identify potential predictive factors for 18F-FDG positivity,these two groups were compared with respect to gender,age at diagnosis of lymphoma,histopathological grade,pattern of follicular dendritic cells,mitotic rate,clinical stage,soluble interleukin-2 receptor levels detected by 18F-FDG-PET,lactate dehydrogenase(LDH) levels,hemoglobin levels,bone marrow involvement,detectability of gastrointestinal lesions by computed tomography(CT) scanning,and follicular lymphoma international prognostic index(FLIPI) ***:Involvement of follicular lymphoma in the stomach,duodenum,jejunum,ileum,cecum,colon,and rectum was identified in 1,34,6,3,2,3,and 6 patients,*** patient had esophageal *** total,19/41(46.3%) patients exhibited true-positive 18F-FDG uptake in the lesions present in their gastrointestinal *** contrast,false-negative 18F-FDG uptake was detected in 24 patients(58.5%),while false-positive 18F-FDG uptake was detected in 5 patients(12.2%).In the former case,2/19 patients had both 18F-FDG-positive lesions and 18F-FDGnegative lesions in the gastrointestinal *** patients with 18F-FDG avidity,the SUVmax value of the involved gast

关键词： Follicular lymphoma Gastrointestinal endoscopy F-fluorodeoxyglucose positron emission tomography Gastrointestinal lymphoma Duodenal neoplasm

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Stochastic Programming Model for Discrete Lotsizing and Scheduling Problem on Parallel Machines

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American Journal of Operations Research 2012年第3期2卷 374-381页

作者： Kensuke Ishiwata Jun Imaizumi Takayuki Shiina Susumu morito Faculty of Business Administration Toyo University Tokyo Japan Faculty of Social Systems Science Chiba Institute of Technology Chiba Japan Global Logistics Kao Corporation Tokyo Japan School of Creative Science and Engineering Waseda University Tokyo Japan

In recent years, it has been difficult for manufactures and suppliers to forecast demand from a market for a given product precisely. Therefore, it has become important for them to cope with fluctuations in demand. From this viewpoint, the problem of planning or scheduling in production systems can be regarded as a mathematical problem with stochastic elements. However, in many previous studies, such problems are formulated without stochastic factors, treating stochastic elements as deterministic variables or parameters. Stochastic programming incorporates such factors into the mathematical formulation. In the present paper, we consider a multi-product, discrete, lotsizing and scheduling problem on parallel machines with stochastic demands. Under certain assumptions, this problem can be formulated as a stochastic integer programming problem. We attempt to solve this problem by a scenario aggregation method proposed by Rockafellar and Wets. The results from computational experiments suggest that our approach is able to solve large-scale problems, and that, under the condition of uncertainty, incorporating stochastic elements into the model gives better results than formulating the problem as a deterministic model.

关键词： Stochastic Programming Lotsizing and Scheduling Parallel Machines Scenario Aggregation Method

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烧结Mo—Re合金的可焊性

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钨钼材料 1989年第4期 66-71页

作者： morito,F

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Development of a Coil-Shape Photocatalysis-Plasma Synergistic Reactor for a Practical and Long-Term Usable Air-Cleaner

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American Journal of Analytical Chemistry 2014年第8期5卷 467-472页

作者： Tsuyoshi Ochiai Yuji Hayashi Erina Ichihashi Tadashi Machida Yoshitsugu Uchida Shoko Tago Yuko morito Akira Fujishima I’m PACT World Co. Ltd. Tokyo Japan Kanagawa Academy of Science and Technology Kawasaki Japan Photocatalysis International Research Center Tokyo University of Science Chiba Japan TANASHIN DENKI Co. Ltd. Tokyo Japan

A novel air-cleaner with a coil-shape photocatalysis-plasma synergistic reactor was developed. The air-cleaner showed 95% ± 1% reduction of a TVOCs concentration in tobacco smoke at “single-pass” condition. Air-purification activity of the air-cleaner was stably-maintained after the treatment of 12,000 cigarettes of tobacco smoke.

关键词： Photocatalysis Plasma Treatment Synergy Volatile Organic Compounds Air-Cleaner

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钼铼合金焊缝的显微组织和机械性能

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钨钼材料 1993年第4期 58-63页

作者： morito,F 钟培全

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碳的离析和沉淀对金属钼晶间脆裂的影响

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中国钼业 1990年第3期14卷 49-54页

作者： Fumio morito 黄开华日本金属材料研究所

为了弄清楚碳对金属钼晶间脆裂的影响,我们用扫描电镜、透射电镜和俄歇谱仪测定了金属钼及其合金的机械性质。主要结果如下:渗碳能改善粗晶粒材料塑性,如一些焊接区的延展性,这些焊接件在常温或低于常温下的延展性是很低的。而在573K以... 详细信息

为了弄清楚碳对金属钼晶间脆裂的影响,我们用扫描电镜、透射电镜和俄歇谱仪测定了金属钼及其合金的机械性质。主要结果如下:渗碳能改善粗晶粒材料塑性,如一些焊接区的延展性,这些焊接件在常温或低于常温下的延展性是很低的。而在573K以上的塑性断裂区间内,碳的掺入能增加材料的强度,但是,减弱了材料的延展性。在稳定的晶界上,当碳的浓度小于10％,在没有任何沉淀时,则能增加材料的屈服应力。这些在俄歇谱仪的曲线中显现出碳离析的各种峰值。当碳的浓度是15—35％时,则在俄歇谱仪图形上很清楚地显现出碳化物的峰值,而在晶界上和基体中可观察到沉淀的碳化物。碳的离析和沉淀的综合作用是更多地增加了屈服应力。这些作用我们从晶界的结合状态进行了讨论。

关键词：金属钼材料塑性粗晶粒焊接件屈服应力基体材料结合状态机械性质脆性转变温度透射电镜

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汽车用合金化镀锌钢板的最新发展

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国外钢铁 1997年第1期22卷 41-45页

作者： morito,N 何立波

合金化镀锌钢板由于具有极好的耐蚀性而获得日益广泛的应用，介绍了在汽车车体生产中所要求的合金化镀锌钢板的各种性能。

关键词：合金化镀锌钢板汽车

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电子束焊接钼和钼—铼合金的特点

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钨钼材料 1994年第3期 42-46页

作者： morito,F 钟培全

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Both Diet and Exercise Are Necessary for Obese CKD Patients: A Pilot Prospective Randomized Controlled Study

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Open Journal of Nephrology 2016年第2期6卷 43-54页

作者： Kazuyuki Noguchi Hirayasu Kai Hirofumi Zempo Fumio Mizuno Masahiro Hagiwara Naoki morito Joichi Usui Chie Saito Shinya Kuno Kunihiro Yamagata Department of Nephrology Faculty of Medicine University of Tsukuba Tsukuba Ibaraki Japan Graduate School of Comprehensive Human Sciences University of Tsukuba Tsukuba Ibaraki Japan

Aim: This study aimed to examine the effects of exercise training on kidney function and nutrition status in obese Chronic Kidney Disease (CKD) patients. Methods: This is a prospective randomized controlled trial. Twelve adult obese CKD patients were randomly assigned to dietary instruction alone group (Group-D) or to both dietary instruction and exercise training group (Group-E). All patients received supervised dietary advice including calorie, protein, and salt intake for a period of 12 weeks. In addition, patients in Group-E underwent a fitness-training program. A change in glomerular filtration rate (GFR) was the main outcome. Secondary outcomes were changes in body mass index, serum creatinine-based estimated-GFR, serum albumin, and albuminuria. Results: Changes in GFR and all secondary outcomes were not statistically significant in either of the two groups. Although exercise training did not appear to significantly affect serum albumin levels in either group, it did present with a large sized effect. Conclusion: Exercise training might not have any effect on kidney function;however, the combination of exercise training along with dietary advice may prove to be more effective in maintaining the nutrition status when compared with dietary instructions alone in obese CKD patients. These results suggest that appropriate exercise training with dietary instructions is recommended for the treatment of obese CKD patients.

关键词： CKD Obesity GFR Diet Exercise Training

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