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Angiosarcoma of the scalp diagnosed by the presence of neck inflammation:a case report

International Journal of Oral Science 2012年第3期4卷 166-169页

作者： Rei Karube Hiroyoshi Sasaki Keiji Shinozuka Yasuhiro Fujisawa toru yanagawa Kenji Yamagata Kojiro Onizawa Fujio Otsuka Hiroki Bukawa Department of Oral and Maxillofacial Surgery Faculty of MedicineUniversity of Tsukuba Department of Dermatology Faculty of MedicineUniversity of Tsukuba

Angiosarcoma is an uncommon malignancy, which spread out from the endothelial cells of vessels. Scalp angiosarcoma with cervical lymph node metastasis is particularly rare. This article describes a rare case of angiosarcoma of the scalp, presenting as neck inflammation. Imaging procedures such as computed tomography （CT）, magnetic resonance image （MRI） and ultrasonography （US） were not sufficient to diagnose this case. A needle biopsy provided an effective and accurate diagnosis of cervical lymph node metastasis. Additional observation and physical examination was required to diagnose the origin of the primary cancerous lesion. Once the angiosarcoma diagnosis was confirmed histologically, sequential weekly and monthly docetaxel （DTX） treatment was effective in preventing reoccurrence. Nonetheless, the optimization of angiosarcoma treatment remains a future goal. Although patients generally describe pain and swelling at the primary lesion site, this patient complained only of painful neck inflammation, without any indication of pain or swelling of the scalp. A revised diagnostic protocol should note that cervical lymph node metastasis of unknown primary origin may result from angiosarcoma of the scalp.

关键词： angiosarcoma docetaxel neck inflammation needle biopsy scalp

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Salivary Duct Carcinoma of the Parotid Gland Definitively Diagnosed by Immunohistochemical Examination of Pulmonary Metastases

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Case Reports in Clinical Medicine 2014年第3期3卷 118-121页

作者： Mei Yonemoto Kojiro Onizawa Kenji Yamagata Shogo Hasegawa toru yanagawa Hiroki Bukawa Department of Oral and Maxillofacial Surgery Faculty of Medicine University of Tsukuba Tsukuba Japan

Salivary duct carcinoma (SDC) is a rare, high-grade, aggressive malignancy, as having a morphologic resemblance to ductal carcinoma of the breast. We present here an atypical SDC of the parotid gland in a 63-year-old man that was diagnosed from immunohistochemical findings. The immunohistochemistry was similar in the parotid lesion and pulmonary metastases in autopsy specimens, but only the latter showed a cribriform pattern and comedolike necrosis. Although the parotid tumor was treated with concurrent chemoradiotherapy and adjuvant chemotherapy for over 21 months, the patient died of respiratory failure caused by advanced pulmonary metastases.

关键词： Salivary Duct Carcinoma (SDC) Immunohistochemistry Parotid Tumor Pulmonary Metastases Autopsy

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Parotid lymph node metastasis in a patient with tongue cancer

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Case Reports in Clinical Medicine 2014年第1期3卷 23-27页

作者： Kenji Yamagata Naomi Ishibashi Kanno Hiroyuki Ito Shogo Hasegawa toru yanagawa Kojiro Onizawa Hiroki Bukawa Department of Oral and Maxillofacial Surgery Faculty of Medi-cine University of Tsukuba Tsukuba Japan

Parotid lymph node (LN) metastasis occurs most commonly from cutaneous squamous cell carcinoma (CSCC) of the head and neck, but rarely from oral squamous cell carcinoma (OSCC). Here, we present a rare case of metastasis to the parotid LN in a patient with tongue cancer. Although usual extent of modified radical neck dissection that includes resection of the tail of the parotid gland is below the line of the mandibular angle and the mastoid process was performed, the parotid LN metastasis occurred. The patient was treated with partial parotidectomy and chemoradiotherapy. One year and two months later, there was no evidence of local recurrence, although multiple lung metastases were observed. We also review the literature on parotid LN metastasis from OSCC.

关键词： Oral Squamous Cell Carcinoma (OSCC) Parotid Lymph Node Metastases Tongue Cancer

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