检索结果-南通市图书馆

Fatigue is not associated with vitamin D deficiency in inflammatory bowel disease patients

World Journal of Gastroenterology 2018年第29期24卷 3293-3301页

作者： Svein Oskar Frigstad Marte Lie Hoivik Jorgen Jahnsen Milada Cvancarova tore grimstad Ingrid Prytz Berset Gert Huppertz-Hauss Oistein Hovde Tomm Bernklev Bjorn Moum Lars-Petter Jelsness-Jorgensen Department of Medicine Vestre Viken Baeum HospitalGjettum 1346Norway Department of Gastroenterology Ostfold Hospital KalnesGralum 1714Norway Department of Health Sciences Ostfold University CollegeHalden 1757Norway Department of Gastroenterology Stavanger University HospitalStavanger 4068Norway Department of Research Otfold Hospital KalnesGralum 1714Norway Department of Gastroenterology Oslo University HospitalOslo 0424Norway Department of Gastroenterology Akershus University HospitalLorenskog 1478Norway Faculty of Health Sciences Oslo Metropolitan UniversityOslo 0130Norway Department of Medicine Alesund Hospital TrustAlesund 6026Norway Department of Gastroenterology Telemark Hospital TrustSkien 3710Norway Department of Medicine Innlandet Hospital TrustGjovik 2819Norway Department of Research and Development Vestfold Hospital TrustTonsberg 3103Norway

AIM To investigate if vitamin D deficiency is associated with fatigue in patients with inflammatory bowel disease(IBD).METHODS IBD patients were recruited from nine hospitals in the southeastern and western regions of Norway to participate in a multicenter cross-sectional study lasting from March 2013 to April 2014. Data were collected by interviews, from medical records and laboratory tests. The Fatigue Questionnaire(FQ) was used to measure fatigue. Linear and logistic regression models were applied to explore the possible association between vitamin D deficiency and total fatigue scores and chronic fatigue, respectively. The analyses were adjusted for age, gender, disease activity, depressive symptoms and sleep *** In total, 405 patients were included in the analyses, of which 227(56%) had Crohn's disease(CD) and 178(44%) had ulcerative colitis(UC). Vitamin D deficiency(< 50 nmol/L) was present in half(203/405) of the patients. Chronic fatigue was reported by 116(29%) of all included patients with substantial fatigue reported by 194(48%). Vitamin D levels were neither associated with total fatigue nor with chronic fatigue. Higher total fatigue scores and chronic fatigue were both associated with increased disease activity scores in patients with UC and CD, but not with increased CRP or fecal calprotectin. In UC patients, female gender was associated with fatigue in the univariate analysis, but no such difference was found when adjusted for elevated disease activity scores. Sleep disturbance and more depressive symptoms were associated with total fatigue scores in both UC and CD patients, but with chronic fatigue only in CD *** In this study, no significant association between fatigue and vitamin D deficiency in IBD patients was revealed.

关键词： Inflammatory bowel disease Crohn's disease Ulcerative colitis Fatigue Chronic fatigue Vitamin D deficiency

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：