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Transnational Urban Governance and the Mega-Event:A Comparative Study of Cape Town,New Delhi & Shanghai

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中国城市研究

中国城市研究 2010年 289-303页

作者： tony Roshan SAMARA George Mason University

This paper is drawn from an ongoing comparative study of mega-events and urban governance in Cape Town,South Africa,New Delhi,India,and Shanghai,***2010 Cape Town will host a number of soccer matches for the World Cup,including one of the semi-finals,New Delhi will host the Commonwealth Games,and Shanghai will host the World *** these are cultural events of a relatively short duration,each of them is,at the same time,explicitly marketed as an urban development project that will leave a lasting socio-economic *** light of the developmental aspirations and claims made by the proponent of mega-events,it is appropriate to ask for what extent these projects can in fact act as mechanisms of development in cities of the global South,where the urban development challenges are,and will remain,*** question is of particular relevance given that the mega-event represents a market-driven approach to urban development in which a transnational network of private and public actors participate in the shaping of the *** order to answer this question,the paper focuses on the process of peripheralization and its relationship to mega-event ***-event preparations have been linked to the displacement of lower income urban populations from city centers as part of the preparation *** paper introduces preliminary data from the three sites and engages with the policy and broader urban development implications of this dramatic transformation of the urban landscape.

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Improved Growth and Stress Tolerance in the Arabidopsis oxtl Mutant Triggered by Altered Adenine Metabolism

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Molecular Plant 2012年第6期5卷 1310-1332页

作者： Suchada Sukrong Kil-Young Yun Patrizia Stadler Charan Kumar tony Facciuolo Barbara A.Moffatt Deane L.Falconec Department of Plant and Soil Science University of KentuckyLexingtonKY 40546USA Present address:Department of Pharmacognosy Faculty of Pharmaceutical SciencesChulalongkorn UniversityBangkokThailand Department of Biological Sciences University of MassachusettsOne University AvenueLowellMA 01854USA Present address:Fungi and Plant Co.Ltd Chungcheongbuk-doRepublic of Korea Department of Biology University of WaterlooWaterlooOntarioCanada

Plants perceive and respond to environmental stresses with complex mechanisms that are often associ- ated with the activation of antioxidant defenses. A genetic screen aimed at isolating oxidative stress-tolerant lines of Arabidopsis thaliana has identified oxtl, a line that exhibits improved tolerance to oxidative stress and elevated temperature but displays no apparent deleterious growth effects under non-stress conditions. Oxtl harbors a muta- tion that arises from the altered expression of a gene encoding adenine phosphoribosyltransferase （APT1）, an enzyme that converts adenine to adenosine monophosphate （AMP）, indicating a link between purine metabolism, whole-plant growth responses, and stress acclimation. The oxtl mutation results in decreased APT1 expression that leads to reduced enzymatic activity. Correspondingly, oxtl plants possess elevated levels of adenine. Decreased APT enzyme activity dir- ectly correlates with stress resistance in transgenic lines that ectopically express APT1. The metabolic alteration in oxtl plants also alters the expression of several antioxidant defense genes and the response of these genes to oxidative chal- lenge. Finally, it is shown that manipulation of adenine levels can induce stress tolerance to wild-type plants. Collectively, these results show that alterations in cellular adenine levels can trigger stress tolerance and improve growth, leading to increases in plant biomass. The results also suggest that adenine might play a part in the signals that modulate responses to abiotic stress and plant growth.

关键词： abiotic/oxidative environmental stress acclimation priming purine signaling salvage pathway thermotolerance.

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Guest editorial

Digital Communications and Networks 2020年第3期6卷 239-240页

作者： Tao Jiang tony Q.S.Quek Zhiguo Ding Mugen Peng Yun Li Huazhong University of Science&Technology China Singapore University of Technology and Design Singapore University of Manchester UK Beijing University of Posts&Telecommunications China Chongqing university of Posts and Telecommunications China

With the rapid deployment of 5G communication networks,the sixthgeneration(6G)mobile network has attracted extensive attention from academia,industry,and government agencies,devoting to identifying critical drivers,performance requirements,and technological *** progress of 6G networks in enhanced mobile broadband,massive machine-type communications and ultra-reliable and lowlatency communications will promote the fast development of new services,e.g.,Augmented Reality(AR),Virtual Reality(VR),holographic communications,Vehicle-to-Everything(V2X),self-driving cars,massive *** services would have different features and *** order to adapt to the ever-changing services,6G should not only be intelligent and open to support full broadband services,but also enhance its capabilities compared with *** will challenge 6G from various aspects,such as rate,delay,coverage,access,energy consumption,interaction,reliability,and degree of intelligence.

关键词： services massive networks

Functionalization of cellulose carbon dots with different elements(N,B and S)for mercury ion detection and anti-counterfeit applications

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Chinese Chemical Letters 2024年第7期35卷 355-359页

作者： Xiaoning Li Quanyu Shi Meng Li Ningxin Song Yumeng Xiao Huining Xiao tony D.James Lei Feng Second Affiliated Hospital of Dalian Medical University Dalian 116023China Hebei Key Lab of Power Plant Flue Gas Multi-Pollutants Control Department of Environmental Science and EngineeringNorth China Electric Power UniversityBaoding 071003China Department of Chemical Engineering and Limerick Pulp&Paper Centre University of New Brunswick15 Dineen DriveFredericton NB E3B 5A3Canada Department of Chemistry University of BathBath BA27AYUnited Kingdom School of Chemistry and Chemical Engineering Henan Normal UniversityXinxiang 453007China

Mercury ion(Hg^(2+)),as one of the most toxic heavy metal ions,accumulates easily in the environment,which can generate potential hazards to the ecosystem and human *** effectively detect and remove Hg^(2+),we fabricated four types of carbon dots(CDs)using carboxymethyl nanocellulose as a carbon source doped with different elements using a hydrothermal *** the CDs exhibited a strong fluorescence emission,excitation-dependent emission and possessed good water ***,the four fluorescent CDs were used for Hg^(2+)recognition in aqueous solution,where the CDs-N exhibited better sensitivity and selectivity for Hg^(2+)detection,with a low limit of detection of 8.29×10^(-6)mol/*** was determined that the fluorescence quenching could be ascribed to a photoinduced charge-transfer processes between Hg^(2+)and the *** addition,the CDs-N were used as a smart invisible ink for anticounterfeiting,information encryption and ***,the CDs-N were immersed into a cellulose(CMC)-based hydrogel network to prepare fluorescent hydrogels capable of simultaneously detecting and adsorbing Hg^(2+).We anticipate that this research will open possibilities for a green method to synthesize fluorescent CDs for metal ion detection and fluorescent ink production.

关键词： Carbon dots Functional groups Hg^(2+)detection Mechanism Anti-counterfeiting

Dual ligand-targeted Pluronic P123 polymeric micelles enhance the therapeutic effect of breast cancer with bone metastases

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Oncology Research 2024年第4期32卷 769-784页

作者： HUAN GAO JIE ZHANG tony GKLEIJN ZHAOYONG WU BING LIU YUJIN MA BAOYUE DING DONGFENG YIN Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics Department of PharmaceuticsCollege of MedicineJiaxing UniversityJiaxing314001China Department of Pharmacy The General Hospital of Xinjiang Military RegionUrumqi830000China Department of Pathology and Medical Biology University Medical Center GroningenUniversity of GroningenGroningen9713 GZThe Netherlands Department of Pathology Laboratory of Experimental OncologyErasmus MCRotterdam3015 GDThe Netherlands Department of Pharmacy Jiaxing Maternal and Child Health Care HospitalAffiliated Hospital of Jiaxing UniversityJiaxing314001China Qinghai Enlu Biotechnology Co. Ltd.Haidong810700China

Bone metastasis secondary to breast cancer negatively impacts patient quality of life and *** treatment of bone metastases is challenging since many anticancer drugs are not effectively delivered to the bone to exert a therapeutic *** improve the treatment efficacy,we developed Pluronic P123(P123)-based polymeric micelles dually decorated with alendronate(ALN)and cancer-specific phage protein DMPGTVLP(DP-8)for targeted drug delivery to breast cancer bone ***(DOX)was selected as the anticancer drug and was encapsulated into the hydrophobic core of the micelles with a high drug loading capacity(3.44%).The DOX-loaded polymeric micelles were spherical,123 nm in diameter on average,and exhibited a narrow size *** in vitro experiments demonstrated that a pH decrease from 7.4 to 5.0 markedly accelerated DOX *** micelles were well internalized by cultured breast cancer cells and the cell death rate of micelle-treated breast cancer cells was increased compared to that of free DOX-treated *** binding of the micelles to hydroxyapatite(HA)microparticles indicated their high affinity for bone.P123-ALN/DP-8@DOX inhibited tumor growth and reduced bone resorption in a 3D cancer bone metastasis *** vivo experiments using a breast cancer bone metastasis nude model demonstrated increased accumulation of the micelles in the tumor region and considerable antitumor activity with no organ-specific histological damage and minimal systemic *** conclusion,our study provided strong evidence that these pH-sensitive dual ligand-targeted polymeric micelles may be a successful treatment strategy for breast cancer bone metastasis.

关键词： Pluronic micelles Targeted nanotherapeutics Nanoparticulate drug delivery system Breast cancer with bone metastasis Therapeutic efficacy

Changes in segment coordination variability and the impacts of the lower limb across running mileages in half marathons:Implications for running injuries

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Journal of Sport and Health Science 2022年第1期11卷 67-74页

作者： tony Lin-Wei Chen Duo Wai-Chi Wong Yan Wang Qitao Tan Wing-Kai Lam Ming Zhang Department of Biomedical Engineering Faculty of EngineeringHong Kong Polytechnic UniversityHong Kong SAR 999077China Li Ning Sports Science Research Center Li Ning(China)Sports Goods Co.LtdBeijing 101111China Hong Kong Polytechnic University Shenzhen Research Institute Shenzhen 518057China Department of Kinesiology Shenyang Sports InstituteShenyang 110102China

Background:Segment coordination variability(CV)is a movement pattern associated with running-related *** can also be adversely affected by a prolonged ***,research on this topic is currently *** purpose of this study was to investigate the effects of a prolonged run on segment CV and vertical loading rates during a treadmill half ***:Fifteen healthy runners ran a half marathon on an instrumental treadmill in a biomechanical *** kinematic and kinetic data were collected every 2 km(from 2 km until 20 km),and the data were processed by musculoskeletal *** CVs were computed from the angle-angle plots of selected pelvis-thigh,thigh-shank,and shank-rearfoot couplings using a modified vector coding *** loading rate of vertical ground reaction force was also calculated.A one-way MANOVA with repeated measures was performed on each of the outcome variables to examine the main effect of running ***:Significant effects of running mileage were found on segment CVs(p≤0.010)but not on loading rate(p=0.881).Notably,during the early stance phase,the CV of pelvis frontal thigh frontal was significantly increased at 20 km compared with the CV at 8 km(g=0.59,p=0.022).The CV of shank transverse *** frontal decreased from 2 km to 8 km(g=0.30,p=0.020)but then significantly increased at both 18 km(g=0.05,p<0.001)and 20 km(g=0.36,p<0.001).Conclusion:At the early stance,runners maintained stable CVs on the sagittal plane,which could explain the unchanged loading rate throughout the half ***,increased CVs on the frontal/transverse plane may be an early sign of fatigue and indicative of possible injury *** studies are necessary for conclusive statements in this regard.

关键词： Coupling angle Endurance running Motion capture analysis Musculoskeletal modeling Vector coding technique

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发展政策:一个针对学生的介绍

世界经济文汇 2005年第3期 19-36页

作者： tony Addison 徐鹏 UNU-WIDER Katajanokanlaituri 6B 00160 Helsinki Finland

本文讨论发展政策的目标,指出这些政策目标多年以来是如何变化的,并且特别关注近来引起重视的贫困削减问题。本文还探讨了经济增长和削减贫困之间的关系。接下来,从增长必须是环境意义上可持续的告诫出发,本文讨论了如何取得经济的增长... 详细信息

本文讨论发展政策的目标,指出这些政策目标多年以来是如何变化的,并且特别关注近来引起重视的贫困削减问题。本文还探讨了经济增长和削减贫困之间的关系。接下来,从增长必须是环境意义上可持续的告诫出发,本文讨论了如何取得经济的增长,并进而回到市场机制与政府在配置社会生产资源时各自的角色这个重大问题上来。随后,本文讨论经济改革是如何推行的,以及相应出现的政治阻力。本文的结论是:正确的发展政策有可能帮助成千上万人脱贫。

关键词：发展政策学生政策目标经济增长生产资源市场机制经济改革可持续削减贫困社会推行脱贫

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saab phoenix

汽车测试报告 2011年第7期 120-125页

作者： paul horrell tony（译）

萨博近来恶梦连连，概念新作Phoenix是对症下药的良方吗？

关键词： saab-phoenix 轿车车型品牌

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低压减载广域配置及站域整定优化方案

电网技术 2015年第8期39卷 2333-2339页

作者：和敬涵陈泽龙 tony Yip 刘琳徐云鹍北京交通大学电气工程学院北京市海淀区100044

为使低压减载方案更具可行性,将低压减载整体方案分为广域配置和站域整定2个层面分别进行优化。在广域层面,提出基于风险分析的低压减载地点优化选择方法,同时兼顾减载后的系统稳定性和经济性。在站域层面,利用站域信息提出基于PV曲线(... 详细信息

为使低压减载方案更具可行性,将低压减载整体方案分为广域配置和站域整定2个层面分别进行优化。在广域层面,提出基于风险分析的低压减载地点优化选择方法,同时兼顾减载后的系统稳定性和经济性。在站域层面,利用站域信息提出基于PV曲线(传输界面潮流与节点电压关系曲线)自适应确定各轮次整定值和减载量,基于模糊综合评价算法优化减载顺序。仿真算例结果验证了所提方案的可行性。

关键词：低压减载风险分析 PV曲线模糊综合评价