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穴位分层多向刺治疗颈型颈椎病30例

中国针灸 2024年第6期44卷 721-722,729页

作者：冯伟许晓冬李非刘慧慧张童薇张卫华河北省沧州中西医结合医院神经康复三科沧州061000 陕西中医药大学第二附属医院名医馆

目的:观察穴位分层多向刺治疗颈型颈椎病的临床疗效。方法:纳入颈型颈椎病患者30例,于双侧颈夹脊穴、后溪、悬钟行穴位分层多向刺,留针30 min,隔日1次,每周3次,治疗4周。观察患者治疗前后及治疗结束后2周(随访时)颈痛视觉模拟量表(VAS)... 详细信息

目的:观察穴位分层多向刺治疗颈型颈椎病的临床疗效。方法:纳入颈型颈椎病患者30例,于双侧颈夹脊穴、后溪、悬钟行穴位分层多向刺,留针30 min,隔日1次,每周3次,治疗4周。观察患者治疗前后及治疗结束后2周(随访时)颈痛视觉模拟量表(VAS)评分、Northwick Park颈痛量表(NPQ)积分,并于治疗后评定临床疗效。结果:治疗后及随访时,患者VAS评分、Northwick Park NPQ积分均较治疗前降低(P<0.05)。30例患者中,痊愈6例,显效20例,无效4例,总有效率为86.7%(26/30)。结论:穴位分层多向刺可改善颈型颈椎病患者的疼痛和颈部症状,提高其生活质量。

关键词：颈椎病颈型针刺分层多向刺视觉模拟量表(VAS)

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信息检索与地质工程知识体系融合的教学研究

中国地质教育 2024年第2期33卷 64-69页

作者：张彤炜张帆宇张虎元兰州大学土木工程与力学学院甘肃兰州730000 西部灾害与环境力学教育部重点实验室甘肃兰州730000

本文针对信息时代学生对搜索资源与学科主体知识体系融合不足的问题展开研究。首先,提出将主体知识体系按照对应的学生能力要求进行模块化分解;然后,从搜索信息、定位信息、利用信息三个角度,引入大语言模型原理、信息智能搜索与订阅、... 详细信息

本文针对信息时代学生对搜索资源与学科主体知识体系融合不足的问题展开研究。首先,提出将主体知识体系按照对应的学生能力要求进行模块化分解;然后,从搜索信息、定位信息、利用信息三个角度,引入大语言模型原理、信息智能搜索与订阅、知识利用与加工三方面教学内容。以培养学生网络信息筛选与管理、信息对比分析与加工、自主搜索知识与学科主体模块融合三方面的能力为目标,设定考核评价体系。学情分析显示,综合目标达成度为0.837。

关键词：地质工程信息检索学科主体知识

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既有建筑主体结构装配式加固及加建研究

建筑科技 2024年第3期8卷 51-54,62页

作者：刘亮张彤炜周书东东莞市建筑科学研究院有限公司广东东莞523820 东莞市建设工程检测中心有限公司广东东莞523820

常规的既有建筑结构改造方式包括加固及加建。这些改造方式的施工仍以现场湿作业居多,而装配式技术可以将既有建筑的改造进程提速,减少现场人力作业及现浇作业工程量。受既有建筑自身条件限制,国内对既有建筑采用装配式技术进行加固及... 详细信息

常规的既有建筑结构改造方式包括加固及加建。这些改造方式的施工仍以现场湿作业居多,而装配式技术可以将既有建筑的改造进程提速,减少现场人力作业及现浇作业工程量。受既有建筑自身条件限制,国内对既有建筑采用装配式技术进行加固及加建的研究较少,装配式技术应用的重心仍在新建建筑上。根据装配式技术应用在既有建筑加固及加建过程中遇到的难点,提出活动模数概念、加建结构采取调节功能的加建技术等措施,同时对相关装配式构件的堆放及运输提出相关见解,以期为类似工程提供借鉴。

关键词：既有建筑装配式加固加建模数

Matched-field localization using a virtual time-reversal processing method in shallow water

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Chinese Science Bulletin 2011年第8期56卷 743-748页

作者： zhang tongwei YANG KunDe MA YuanLiang College of Marine Northwestern Polytechnical University Xi'an 710072 China

Time-reversal processing(TRP) is an implementation of matched-field processing(MFP) where the ocean itself is used to construct the replica *** paper introduces virtual time-reversal processing(VTRP) that is implemented electronically at a receiver array and simulates the kind of processing that would be done by an actual TRP during the reciprocal propagation *** is a forward propagation process,while VTRP is a back-propagation process,which exploits the properties of reciprocity and superposition and is realized by weighting the replica surface with the complex conjugate of the data received on the corresponding element,followed by summation of the processed received *** number of parabolic equation computational grids of VTRP is much smaller than that of MFP in a range-dependent *** a result,the localization surface of VTRP can be formed faster than its MFP counterpart in a range-dependent *** performance of VTRP for source localization is validated through numerical simulations and data from the Mediterranean Sea.

关键词：匹配场处理时间反转定位方法虚拟多功能一体机浅水传播过程定位表面

27-Hydroxycholesterol/liver X receptor/apolipoprotein E mediates zearalenone-induced intestinal immunosuppression:A key target potentially linking zearalenone and cancer

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Journal of Pharmaceutical Analysis 2024年第3期14卷 371-388页

作者： Haonan Ruan Jing zhang Yunyun Wang Ying Huang Jiashuo Wu Chunjiao He tongwei Ke Jiaoyang Luo Meihua Yang Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine Ministry of EducationInstitute of Medicinal Plant DevelopmentChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing100193China

Zearalenone(ZEN)is a mycotoxin that extensively contaminates food and feed,posing a significant threat to public ***,the mechanisms behind ZEN-induced intestinal immunotoxicity remain *** this study,Sprague-Dawley(SD)rats were exposed to ZEN at a dosage of 5 mg/kg/day *** a duration of 14 *** results demonstrated that ZEN exposure led to notable pathological alterations and immunosuppression within the ***,ZEN exposure caused a significant reduction in the levels of apolipoprotein E(ApoE)and liver X receptor(LXR)(P<0.05).Conversely,it upregulated the levels of myeloid-derived suppressor cells(MDSCs)markers(P<0.05)and decreased the presence of 27-hydroxycholesterol(27-HC)in the intestine(P<0.05).It was observed that ApoE or LXR agonists were able to mitigate the immunosuppressive effects induced by ***,a bioinformatics analysis highlighted that the downregulation of ApoE might elevate the susceptibility to colorectal,breast,and lung *** findings underscore the crucial role of the 27-HC/LXR/ApoE axis disruption in ZEN-induced MDSCs proliferation and subsequent inhibition of T lymphocyte activation within the rat ***,ApoE may emerge as a pivotal target linking ZEN exposure to cancer development.

关键词： Zearalenone Intestinal immunosuppression Apolipoprotein E Bioinformatics analysis Cancer

Use of the Jiaolong manned submersible for accurate mapping of deep-sea topography and geomorphology

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Science China Earth Sciences 2018年第8期61卷 1148-1156页

作者： tongwei zhang Jialing TANG Zhengguang LI Yubin ZHOU Xiangxin WANG National Deep Sea Center Qingdao 266237 China Laboratory for Marine Geology Qingdao National Laboratory for Marine Science and Technology Qingdao 266061 China Joint Laboratory for Ocean Observation and Detection Qingdao National Laboratory for Marine Science and Technology Qingdao 266237 China

High-resolution bathymetric side-scan sonar(BSSS) performs the functions of traditional side-scan sonar, while also providing a depth-sounding function that allows simultaneous measurement of seafloor topography and geomorphology. Submarine microtopography and microgeomorphology detection ability and advanced underwater acoustic digital communication are important technical capabilities of the Jiaolong manned submersible. High resolution BSSS achieved accurate detection of seafloor topography and geomorphology at a depth of 7000 m, and successful mapping of local microtopography and microgeomorphology in the Mariana Trench.

关键词：地形学入水驾驶深海高分辨率技术能力数字通讯水下声学

Determination of the heating efficiency of magnetotactic bacteria in alternating magnetic field

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Journal of Oceanology and Limnology 2021年第6期39卷 2116-2126页

作者： tongwei zhang Huangtao XU Jia LIU Yongxin PAN Changqian CAO Key Laboratory of Earth and Planetary Physics Institute of Geology and GeophysicsInnovation Academy for Earth ScienceChinese Academy of SciencesBeijing 100029China Innovation Academy for Earth Science Chinese Academy of SciencesBeijing 100029China College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijing 100049China France-China Joint Laboratory for Evolution and Development of Magnetotactic Multicellular Organisms Chinese Academy of SciencesBeijing 100029China

Magnetotactic bacteria(MTB)intact cells have been applied in magnetic hyperthermia therapy of tumor,showing great efficiency in heating for tumor cell ***,the detailed magnetic hyperthermia properties and optimum heat production conditions of MTB cells are still poorly understood due to lack of standard measuring *** specific absorption rate(SAR)of MTB cells is often measured by home-made equipment at a limited frequency and magnetic field *** this study,we have used a commercial standard system to implement a comprehensive study of the hyperthermic response of Magnetospirillum gryphiswaldense MSR-1 strain under 7 frequencies of 144-764 kHz,and 8 field amplitudes between 10 and 45 kA/*** measurement results prove that the SAR of MTB cells increases with magnetic field frequency and amplitude within a certain *** combination with the magnetic measurements,it is determined that the magnetic hyperthermia mechanism of MTB mainly follows the principle of hysteresis loss,and the heat efficiency of MTB cells in alternating magnetic field are mainly aff ected by three parameters of hysteresis loop,saturation magnetisation,saturation remanent magnetisation,and *** when we culture MTB in LA-2 medium containing sodium nitrate as source of nitrogen,the SAR of MTB LA-2 cells with magnetosomes arranged in chains can be as high as 4925.6 W/g(in this work,all SARs are calculated with iron mass)under 764 kHz and 30 kA/m,which is 7.5 times than current commercial magnetic particles within similar size range.

关键词： magnetotactic bacteria(MTB) hyperthermia rock magnetism alternating magnetic field(AMF)

Kinetic Model of Gaseous Alkanes Formed from Coal in a Confined System and Its Application to Gas Filling History in Kuqa Depression,Tarim Basin,Northwest China

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Acta Geologica Sinica(English Edition) 2011年第4期85卷 911-922页

作者： LIU Quanyou zhang tongwei JIN Zhijun QIN Shengfei TANG Yongchun LIU Wenhui Exploration and Production Research Institute SINOPECBeijing 100083China Bureau of Economic Geology The University of Texas at Austin University StationAustinTexas 78713- 8924USA Power Environmental and Energy Research InstituteCalifornia 91722USA Research Institute of Petroleum Exploration and Development PetroChinaBeijing 100083China

Based on the pyrolysis products for the Jurassic low-mature coal under programmed temperature,and chemical and carbon isotopic compositions of natural gas from the Kuqa Depression, the genetic origin of natural gas was determined,and then a gas filling model was established,in combination with the geological background of the Kuqa *** active energy of CH_4,C_2H_6 and C_3H_8 was gotten after the data of pyrolysis gas products under different heating rates（2℃/h and 20℃/h）were fitted by the Gas Oil Ratio（GOR）Isotope Model *** the frequency factor（Af）was chosen as 1×10^（14）,the active energy of CH_4,C_2H_6 and C_3H_8 was 58 kcal/mol,57 kcal/mol and 54 kcal/ mol,*** distributive ranges of theδ^（13）C_1,δ^（13）C_2 andδ^（13）C_3 values for the pyrolysis gas products are-35.9‰to-30.7‰,-26.2‰to-21.3‰and-26.4‰to-22.7‰,*** of the natural gases from the Kuqa Depression are dominated by hydrocarbon gases,with the high gas dryness（C_1/C_（1-4））at the middle and northern parts of the depression and the low values at both east and west sides and the southern *** carbon isotopes of methane and its homologs as a typical coal-type gas are enriched in ^（13）C,and the distributive range of theδ^（13）C_1,δ^（13）C_2 andδ^（13）C_3 value is-32‰to -38‰,-22‰to-24‰and-20‰to-22‰,respectively,with the carbon isotopes of gaseous alkanes being less negative with the carbon *** the ethane being enriched in ^（13）C the increasing tendency of the geological reserve of natural gas in the Kuqa Depression is *** observed change is consistent with the results of pyrolysate gas yield of coal as a potential gas source in the Kuqa Depression,suggesting natural gas was thermally derived from the humic organic matters and the carbon isotopes of gaseous alkanes would coarsely predict the geological reserve of gas in the Kuqa *** the simulation of kinetic processes of gas generation for the Jurassic coal in the Kuqa Depression,the gas in th

关键词： natural gas gas kinetic carbon isotope gas-filling history Kuqa Depression

我国南方不同地区寒武系页岩含气性差异主控因素探讨

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地学前缘 2023年第3期30卷 1-13页

作者：张同伟罗欢孟康 Bureau of Economic Geology Jackson School of GeosciencesThe University of Texas at AustinAustin TX 78713USA 兰州大学地质科学与矿产资源学院/甘肃省西部矿产资源重点实验室甘肃兰州730000 西北大学地质学系大陆动力学国家重点实验室陕西西安710069

中国南方寒武系富有机质页岩具有很大的页岩气资源潜力,但不同地区的勘探效果差异较大。本文分析了近年来我国寒武系页岩含气性研究进展,讨论了寒武系页岩的储层特征、总有机碳(TOC)含量、孔隙度和构造保存条件等因素对页岩含气性的影... 详细信息

中国南方寒武系富有机质页岩具有很大的页岩气资源潜力,但不同地区的勘探效果差异较大。本文分析了近年来我国寒武系页岩含气性研究进展,讨论了寒武系页岩的储层特征、总有机碳(TOC)含量、孔隙度和构造保存条件等因素对页岩含气性的影响。中上扬子地区的寒武系富有机质页岩主要发育在绵阳—长宁裂陷槽、鄂西裂陷槽和湘黔渝深水陆棚—斜坡等沉积相区。寒武系页岩的孔隙度主要分布在1%~6%,孔隙以微孔和介孔占主导,总体以孤立密集发育的海绵状有机孔为主,区别于志留系龙马溪组页岩极为发育的气泡状有机孔。位于裂陷槽环境的寒武系筇竹寺组/水井沱组页岩的有机孔隙发育程度较好(有机质平均面孔率可达20%~50%),且无机孔也对总孔隙度有所贡献;页岩现今含气量为1.5~5.5 m^(3)/t,是理论总生成气量的10%~30%(最大甚至超过50%),反映页岩气保存条件总体较好。而位于深水陆棚—斜坡环境的寒武系牛蹄塘组页岩有机孔发育程度较差(有机质平均面孔率小于20%),页岩现今含气量基本小于1.0 m^(3)/t,不足理论总生成气量的10%,反映页岩气可能发生过大规模散失,页岩气保存条件较差。中上扬子地区寒武系富有机质页岩底部通常存在区域性的不整合面,在沉积之后也普遍经历过强烈的后期构造抬升作用,均可能造成油气的散失。相比之下,绵阳—长宁裂陷槽和鄂西裂陷槽环境下的寒武系页岩孔隙发育情况和构造保存条件相对较好,富有机质层段内发育的钙质页岩/泥灰岩夹层可能会限制油气在垂向上的运移和散失,为寒武系页岩气的保存创造了有利条件,应是寒武系页岩气勘探的重点目标,这也与我国目前的寒武系页岩气勘探实际相对应。

关键词：页岩气含气性寒武系有机孔构造保存条件中国南方