检索结果-南通市图书馆

Children with infectious pneumonia caused by Ralstonia insidiosa:A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2023年第9期11卷 2002-2008页

作者： Shuang-Zhu Lin Mei-Jia Qian Yan-Wei Wang Qian-Dui Chen Wan-Qi Wang Jia-Yi Li rui-tong yang Xin-Yao Wang Chun-Yu Mu Kai Jiang Diagnosis and Treatment Center for Children Affiliated Hospital of Changchun University of Chinese MedicineChangchun 130021Jilin ProvinceChina Department of Imaging Affiliated Hospital of Changchun University of Chinese MedicineChangchun 130021Jilin ProvinceChina College of Integrated Chinese and Western Medicine Changchun University of Chinese MedicineChangchun 130117Jilin ProvinceChina College of Traditional Chinese Medicine Changchun University of Chinese MedicineChangchun 130117Jilin ProvinceChina

BACKGROUND Ralstonia is a Gram-negative non-fermentative bacterium widespread in nature,and includes four species,Ralstonia pickettii,Ralstonia solanacearum,Ralstonia mannitolilytica,and Ralstonia insidiosa,which were proposed in *** is mainly found in the external water environment,including municipal and medical water purification *** bacterium has low toxicity and is a conditional *** has been reported in recent years that infections due to Ralstonia are *** studies have shown that most cases of infection are caused by Ralstonia pickettii,a few by Ralstonia mannitolilytica,and infections caused by Ralstonia insidiosa are *** SUMMARY A 2-year-old Chinese child suffered from intermittent fever and cough for 20 d and was admitted to hospital with bronchial *** and alveolar lavage fluid culture confirmed Ralstonia insidiosa *** infection was well controlled after treatment with meropenem and *** Ralstonia infections are increasing,and we report a rare case of Ralstonia insidiosa infection in a *** should be vigilant about Ralstonia infections.

关键词： Children Infections Ralstonia insidiosa Pneumonia Treatment Case report

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

精细的空域可扩展性视频编码

河南大学学报（自然科学版） 2005年第3期35卷 80-82页

作者：朱强仝瑞阳浙江传媒学院计算机系杭州310018 平顶山工学院计算机系河南平顶山467000

提出一种灵活高效的空域可扩展性算法———精细的空域可扩展性编码(FGSS),对此算法进行了描述,给出了编码和解码框图,并对其编码实现进行了讨论.

关键词：视频编码码率参考图像

基于混沌粒子群优化算法的CNN图像边缘提取方法

在线全文

学校读者我要写书评

暂无评论

河南大学学报（自然科学版） 2012年第3期42卷 309-314页

作者：仝瑞阳刘刚森河南城建学院计算机科学与工程系河南平顶山467036 河南大学新闻与传播学院河南开封475001

细胞神经网络(Cellular Neural Network,CNN)具有能够高速并行计算,易于硬件实现等特点,使其在未来的图像处理方面展现出了广阔的应用前景.CNN较好地探测出图像中边缘的关键在于设计出一组较好的模板参数.提出一种基于混沌粒子群优化算... 详细信息

细胞神经网络(Cellular Neural Network,CNN)具有能够高速并行计算,易于硬件实现等特点,使其在未来的图像处理方面展现出了广阔的应用前景.CNN较好地探测出图像中边缘的关键在于设计出一组较好的模板参数.提出一种基于混沌粒子群优化算法求解模板参数的方法,一方面,避免了分析细胞神经网络动态性能的一系列复杂过程;另一方面,通过将搜索过程映射为对混沌轨道的遍历过程,可以使得搜索过程避免陷入局部极小,并且在模板参数的范围内能快速找到最优模板值.仿真实验表明,利用该方法设计出来的CNN去探测图像中的边缘比已有结果和利用几种经典边缘提取算子得到的边缘结果更加精确.

关键词：细胞神经网络混沌粒子群优化算法图像边缘提取模板参数

山东地区水貂肠炎病毒VP_2基因的克隆和测序分析

在线全文

学校读者我要写书评

暂无评论

中国兽医杂志 2016年第12期52卷 28-30,34页

作者：陈童杨瑞梅单虎青岛农业大学山东省预防兽医学重点实验室山东青岛266109

本研究对潍坊、烟台、威海和青岛地区的疑似水貂病毒性肠炎病毒（MEV）粪便样品进行检测,并在9份样品QD1309、QD1407、WH1407、WH1408、WH1508、WH1509、WF1310、WF1408、YT1408中扩增出VP2基因,和Gen Bank上已经公布的4株MEV参考株的VP... 详细信息

本研究对潍坊、烟台、威海和青岛地区的疑似水貂病毒性肠炎病毒（MEV）粪便样品进行检测,并在9份样品QD1309、QD1407、WH1407、WH1408、WH1508、WH1509、WF1310、WF1408、YT1408中扩增出VP2基因,和Gen Bank上已经公布的4株MEV参考株的VP2基因进行序列分析,结果显示,13份MEV VP2基因的核苷酸和氨基酸均有较高的同源性,分别为97.5%99.8%和96.9%99.7%。系统发育进化树表明,QD1309、YT1408、MEV-Beregovoj-Bincentr（MEV-BB）、MEV-e属于同一个组群,不同毒株主要在第5、62、87、101、232、236、279、300、534位氨基酸发生了替换。本研究对水貂细小病毒流行株的主要衣壳蛋白VP2的编码蛋白进行遗传变异分析,为更好地预防和控制貂源细小病毒提供基础。

关键词：水貂肠炎病毒 VP2基因遗传变异分析

Microglia lactylation in relation to central nervous system diseases

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第1期20卷 29-40页

作者： Hui yang Nan Mo Le tong Jianhong Dong Ziwei Fan Mengxian Jia Juanqing Yue Ying Wang School of Pharmacy Hangzhou Normal UniversityHangzhouZhejiang ProvinceChina Department of Clinical Laboratory The Fourth Clinical Medical College of Zhejiang University of Traditional Chinese Medicine(Hangzhou First People’s Hospital)HangzhouZhejiang ProvinceChina College of Medical Veterinary and Life SciencesUniversity of GlasgowGlasgowUK Department of Orthopedics(Spine Surgery) the First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiang ProvinceChina Department of Pathology Affiliated Hangzhou First People’s HospitalWestlake University School of MedicineHangzhouZhejiang ProvinceChina Department of Clinical Research Center Affiliated Hangzhou First People’s HospitalWestlake University School of MedicineHangzhouZhejiang ProvinceChina

The development of neurodegenerative diseases is closely related to the disruption of central nervous system ***,as innate immune cells,play important roles in the maintenance of central nervous system homeostasis,injury response,and neurodegenerative *** has been considered a metabolic waste product,but recent studies are revealing ever more of the physiological functions of *** is an important pathway in lactate function and is involved in glycolysis-related functions,macrophage polarization,neuromodulation,and angiogenesis and has also been implicated in the development of various *** review provides an overview of the lactate metabolic and homeostatic regulatory processes involved in microglia lactylation,histone versus non-histone lactylation,and therapeutic approaches targeting ***,we summarize the current research on microglia lactylation in central nervous system diseases.A deeper understanding of the metabolic regulatory mechanisms of microglia lactylation will provide more options for the treatment of central nervous system diseases.

关键词： brain central nervous system glycolysis immune response inflammation lactate metabolism lactate lactylation microglia neurodegenerative diseases

Study on the hydrogen absorption properties of a YGdTbDyHo rare-earth high-entropy alloy

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 127-135页

作者： tongyue Li Ziliang Xie Wenjiao Zhou Huan tong Dawen yang Anjia Zhang Yuan Wu Xiping Song State Key Laboratory for Advanced Metals and Materials University of Science and Technology BeijingBeijing 100083China Whole Win(Beijing)Materials Sci.&Tech.Co. Ltd.Beijing 100083China

This study investigated the microstructure and hydrogen absorption properties of a rare-earth high-entropy alloy(HEA),*** indicated that the YGdTbDyHo alloy had a microstructure of equiaxed grains,with the alloy elements distributed *** hydrogen absorption,the phase structure of the HEA changed from a solid solution with an hexagonal-close-packed(HCP)structure to a high-entropy hydride with an faced-centered-cubic(FCC)structure without any secondary phase *** alloy demonstrated a maximum hydrogen storage capacity of 2.33 H/M(hydrogen atom/metal atom)at 723 K,with an enthalpy change(ΔH)of-141.09 kJ·mol^(-1)and an entropy change(ΔS)of-119.14 J·mol^(-1)·K^(-1).The kinetic mechanism of hydrogen absorption was hydride nucleation and growth,with an apparent activation energy(E_(a))of 20.90 kJ·mol^(-1).Without any activation,the YGdTbDyHo alloy could absorb hydrogen quickly(180 s at 923 K)with nearly no incubation period *** reason for the obtained value of 2.33 H/M was that the hydrogen atoms occupied both tetrahedral and octahedral *** results demonstrate the potential application of HEAs as a high-capacity hydrogen storage material with a large H/M ratio,which can be used in the deuterium storage field.

关键词： rare-earth high-entropy alloy hydrogen absorption capacity pressure–composition–temperature curves kinetics

Janus MXene film with gradient structure for highly efficient terahertz and infrared electromagnetic absorption

在线全文

学校读者我要写书评

暂无评论

Nano Research 2025年第1期18卷 434-442页

作者： Shaodian yang Weiqiang Huang Zhiqiang Lin Zibo Chen Rongliang yang Yi Jia Xuebin Liu rui Wang Zhiping Zeng Yougen Hu Huanjun Chen Xuchun Gui11 State Key Laboratory of Optoelectronic Materials and Technologies School of Electronics and Information TechnologySun Yat-sen UniversityGuangzhou 510275China National Key Laboratory of Materials for Integrated Circuits Shenzhen Institute of Advanced Electronic MaterialsShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China China Academy of Aerospace Science and Innovation Beijing 100176China Guangdong Province Key Laboratory of Display Material and Technology Guangzhou 510275China School of Materials Science and Engineering Sun Yat-sen UniversityGuangzhou 510275China

Electromagnetic interference (EMI) shielding inhigh-frequency range, especially the rapidly growing terahertz(THz) frequency range, attracts increasing attention due tothe potential application of terahertz in 6G wirelesscommunication, and security inspection. However, traditionalconductive EMI films typically achieve high shieldingeffectiveness through strong reflection, which may causesecondary pollution to other devices. Here, a gradientstructure strategy was proposed to constructTi_(3)C_(2)Tx/hydroxypropyl methyl cellulose (HPMC) film, in whichthe content of Ti_(3)C_(2)Tx gradually increases along the thicknessdirection, resulting in different conductivity of the two surfaces(surface-M and surface-H) for the film. The obtained gradientfilmexhibits an EMI shielding efficiency of over 48.5 dB in theTHz range (0.2-1.6 THz) at a thickness of 40 μm. Especially,as the THz waves incident from the surface-H to the film, the absorption effectiveness reaches 48.2 dB (average absorbedpower loss up to 91.4%), and the reflection effectiveness is only 0.3 dB. In additions, the gradient-film also demonstrates ahigh absorption rate of 95.5% in the infrared band (2.5-16.7 μm). Moreover, the gradient-film exhibits an excellent tensilestress and Young’s modulus value of 173.1 MPa and 2.8 GPa, respectively. Therefore, the gradient-film proposed in thiswork, with excellent electromagnetic absorption in both THz and infrared band, provides a promising candidate for the nextgenerationEMI shielding applications.

关键词： electromagnetic interference shielding Janus film terahertz MXene

Targeting Epac2 and GluA3-containing AMPARs:a novel therapeutic strategy for Alzheimer's disease

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第11期20卷 3223-3224页

作者： tong Zhang Martina Schmidt Department of Molecular Pharmacology Groningen Research Institute of PharmacyUniversity of GroningenGroningenThe Netherlands School of Pharmacy Tianjin Medical UniversityTianjinChina

Alzheimer's disease(AD)is a neurodegenerative disease that manifests progressive decline in memory and *** the early stage of AD,memory retrieval is impaired preceding memory acquisition and consolidation(Roy et al.,2016).Prior to the onset of symptoms,pathological amyloid-β(Aβ)plagues and tau protein tangles accumulate in extracellular and intracellular spaces,respectively,leading to *** these hallmark pathologies,Aβ is proposed to be the primary etiology by triggering a cascade of pathogenic events,including neuroinflammation,oxidative stress,tau hyperphosphorylation,synaptic/neuronal dysfunction,and neuronal death(Zhang et al.,2023b).

关键词： Alzheimer impaired Aβ

Apolipoprotein E elicits targetdirected miRNA degradation to maintain neuronal integrity

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第9期20卷 2577-2578页

作者： Jiazi Tan Chin-tong Ong Temasek Life Sciences Laboratory National University of SingaporeSingapore Department of Biological Sciences National University of SingaporeSingapore

Apolipoprotein E has diverse functions in neurons:Apolipoprotein E(ApoE)is a glycoprotein that primarily regulates lipid metabolism and transport in the central nervous *** are three predominant human ApoE protein isoforms with cysteine and arginine substitutions at amino acid positions 112 and 158 that impact their lipidation and related functions(Flowers and Rebeck,2020).ApoE2 is characterized by Cys112 and Cys158,ApoE3 by Cys112 and Arg158,whereas ApoE4 contains Arg112 and Arg158.

关键词： metabolism glycoprotein maintain