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A comparative single-pulse shock tube experiment and kinetic modeling study on pyrolysis of cyclohexane,methylcyclohexane and ethylcyclohexane

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Defence Technology（防务技术） 2023年第2期20卷 137-148页

作者： Jin-hu liang Shu-tong Cao fei li Xiao-liang li Rui-ning He Xin Bai Quan-De Wang Yang li School of Environmental and Safety Engineering North University of ChinaTaiyuan030051People's Republic of China Science and Technology on Combustion Internal Flow and Thermostructure LaboratorySchool of AstronauticsNorthwestern Polytechnical UniversityXi'an 710072People's Republic of China Low Carbon Energy Institute and School of Chemical Engineering China University of Mining and TechnologyXuzhou 221008People's Republic of China

The pyrolysis of cyclohexane,methylcyclohexane,and ethylcyclohexane have been studied behind reflected shock waves at pressures of 5 and10 bar and at temperatures of 930-1550 K for 0.05%fuel diluted by Argon.A single-pulse shock tube(SPST)is used to perform the pyrolysis experiments at reaction times varying from 1.65 to 1.74 *** products are obtained and quantified using gas chromatography analysis.A flame ionization detector and a thermal conductivity detector are used for species identification and *** modeling has been performed using several detailed and lumped chemical kinetic *** in modeling results among the kinetic models are *** path analysis and sensitivity analysis are performed to determine the important reactions controlling fuel pyrolysis and their influence on the predicted concentrations of reactant and product species *** present work provides new fundamental knowledge in understating pyrolysis characteristics of cyclohexane compounds and additional data set for detailed kinetic mechanism development.

关键词： Cyclohexane Alkylated cyclohexane Single-pulse shock tube Pyrolysis Kinetic modeling

电膜萃取技术提取生物检材中滥用药物的研究进展

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分析测试学报 2025年第1期44卷 25-33页

作者：高同飞董壮壮沈先涛黄垂秀华中科技大学同济医学院法医学系湖北武汉430030 华中科技大学同济医学院公共卫生学院教育部环境与健康重点实验室湖北武汉430030

电膜萃取技术(EME)是一种绿色高效的新型样品前处理技术,因其选择性好、净化能力强等优点,近年来被广泛应用于食品分析、环境分析、药物分析以及法医毒物分析领域。该文总结了近五年EME在滥用药物提取中的研究进展,重点总结了EME从不同... 详细信息

电膜萃取技术(EME)是一种绿色高效的新型样品前处理技术,因其选择性好、净化能力强等优点,近年来被广泛应用于食品分析、环境分析、药物分析以及法医毒物分析领域。该文总结了近五年EME在滥用药物提取中的研究进展,重点总结了EME从不同生物检材(如血液、尿液、唾液、毛发和组织等)中提取富集滥用药物的应用情况,特别关注了其对于毒品、新精神活性物质(NPS)以及临床类滥用药物的分离性能。同时,也探讨了EME应用于法医学领域面临的挑战,并展望了其未来的发展方向。

关键词：电膜萃取法医毒物分析样品前处理滥用药物毛发唾液

Translocation of ssDNA through Charged Graphene Nanopores:Effect of the Charge Density

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Chinese Journal of Polymer Science 2024年第12期42卷 2048-2058,I0013页

作者： Yuan-Shuo Zhang Zhi-Ya Qi Ming-Ming Ding Ming-Lun li tong-fei Shi School of Chemical Engineering and light Industry Guangdong University of TechnologyGuangzhou510006China Jieyang Branch of Chemistry and Chemical Engineering Guangdong Laboratory Jieyang515200China Department of Polymer Science and Engineering University of Massachusetts Amherst120 Governors DriveAmherstMassachusetts01003USA

Nanopore sequencing harnesses changes in ionic current as nucleotides traverse a nanopore,enabling real-time decoding of DNA/RNA *** instruments for the dynamic behavior of substances in the nanopore on the molecular scale are still very limited *** study employs all-atom molecular dynamics(MD)simulations to explore the impact of charge densities on graphene nanopore in the translocation of single-stranded DNA(ssDNA).We find that the magnitude of graphene’s charge,rather than the charge disparity between ssDNA and graphene,significantly influences ssDNA adsorption and translocation ***,high negative charge densities on graphene nanopores are shown to substantially slow down ssDNA translocation,highlighting the importance of hydrodynamic effects and electrostatic *** indicates translocation is crucial for achieving distinct ionic current blockades,which plays a central role for DNA sequencing *** findings suggest that negatively charged graphene nanopores hold considerable potential for optimizing DNA sequencing,marking a critical advancement in this field.

关键词： Nanopore sequencing Graphene nanoslit DNA translocation Electroosmotic flow

RARRES2 regulates lipid metabolic reprogramming to mediate the development of brain metastasis in triple negative breast cancer

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Military Medical Research 2024年第1期11卷 34-49页

作者： Yi-Qun li Fang-Zhou Sun Chun-Xiao li Hong-Nan Mo Yan-tong Zhou Dan Lv Jing-tong Zhai Hai-li Qian fei Ma Department of Medical Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China State Key Laboratory of Molecular Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

Background Triple negative breast cancer(TNBC),the most aggressive subtype of breast cancer,is characterized by a high incidence of brain metastasis(BrM)and a poor *** the most lethal form of breast cancer,BrM remains a major clinical challenge due to its rising incidence and lack of effective treatment *** evidence suggested a potential role of lipid metabolic reprogramming in breast cancer brain metastasis(BCBrM),but the underlying mechanisms are far from being fully *** Through analysis of BCBrM transcriptome data from mice and patients,and immunohistochemical validation on patient tissues,we identified and verified the specific down-regulation of retinoic acid receptor responder 2(RARRES2),a multifunctional adipokine and chemokine,in BrM of *** investigated the effect of aberrant RARRES2 expression of BrM in both in vitro and in vivo *** signaling pathway components were evaluated using multi-omics *** were performed to elucidate the regulation of lipid metabolic reprogramming of *** We found that downregulation of RARRES2 is specifically associated with BCBrM,and that RARRES2 deficiency promoted BCBrM through lipid metabolic ***,reduced expression of RARRES2 in brain metastatic potential TNBC cells resulted in increased levels of glycerophospholipid and decreased levels of triacylglycerols by regulating phosphatase and tensin homologue(PTEN)-mammalian target of rapamycin(mTOR)-sterol regulatory element-binding protein 1(SREBP1)signaling pathway to facilitate the survival of breast cancer cells in the unique brain *** Our work uncovers an essential role of RARRES2 in linking lipid metabolic reprogramming and the development of ***2-dependent metabolic functions may serve as potential biomarkers or therapeutic targets for BCBrM.

关键词： RARRES2 lipid metabolic reprogramming Brain metastasis(BrM) Breast cancer

Exposure to Intimate Partner Violence, Core Self-Evaluations, and Psychological Adaptation of Chinese Adolescents

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International Journal of Mental Health Promotion 2021年第1期23卷 111-120页

作者： Tao li fei Feng Che tong Nah School of Education South-Central University for NationalitiesWuhan430074China Department of General Education Wuhan Technology and Business UniversityWuhan430065China Sekolah Menengah Chong Hwa Kuantan JohorMalaysia

This study aimed to investigate the link between the exposure to intimate partner violence(IPV),core self-evaluations(CSE),and psychological adaptation of Chinese adolescents,through analysis of the results from the Survey of Children’s Exposure to Domestic Violence Scale,Core Self-Evaluations Scale,and Strengths and Difficulties Questionnaire,involving a total of 597 Chinese middle school *** is indicated that the exposure to IPV is positively correlated with lower levels of psychological adaptation and CSE,and CSE is positively correlated with higher levels of psychological *** analysis revealed that CSE partially mediated the association between the exposure to IPV and psychological *** results suggest that educators and parents should help adolescents tackle their emotional and behavioral problems by reducing the risk of IPV exposure and increasing their CSE.

关键词： Intimate partner violence core self-evaluations psychological adaptation Chinese adolescents

Investigation of the dynamic characteristics of a dual rotor system and its start-up simulation based on finite element method

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2013年第4期14卷 268-280页

作者： Zhong-xiu fei Shui-guang tong Chao WEI Institute of Chemical Machinery Engineering Zhejiang University Mechanical Design Institute Zhejiang University Institute of Thermal Engineering and Power Systems Zhejiang University

Recently,the finite element method(FEM) has been commonly applied in the engineering analysis of rotor *** moments,rotary inertia,transverse shear deformation and gravity can be included in computational models of rotor-bearing *** this paper,a finite element model and its solution method are presented for the calculation of the dynamics of dual rotor systems.A typical structure with two rotor shafts is discussed and the procedure for obtaining the coupling motion equations of the subsystems is illustrated.A computer program is developed to solve critical speeds and to simulate the transient *** influence of gyroscopic moments on co-rotation and counter-rotation is analyzed,and the effect of the speed ratio on critical speed is *** dynamic characteristics under different conditions of increasing speed during start-up are demonstrated by comparison with transient nodal *** presented model provides a complete foundation for further investigation of the dynamics of dual rotor systems.

关键词： Dual rotor system Critical speed Transient response Finite element method(FEM)

Mesenchymal Stem Cells Proliferation on Konjac Glucomannan Microcarriers:Effect of Rigidity

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Chinese Journal of Polymer Science 2022年第9期40卷 1080-1089页

作者： Xing-Ran Yan Juan li Xiang-Ming Na tong li Yu-fei Xia Wei-Qing Zhou Guang-Hui Ma State Key Laboratory of Biochemical Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China

Mesenchymal stem cells(MSCs)have attracted great attention as a source of cells for regenerative medicine owing to their self-renewal ability and multiple differentiation ***,the serious shortage of MSCs and the difficulty of maintaining the differentiation potential during culture in vitro limit their *** culture technology is an effective method to realize large-scale culture of MSCs,whereas the effect of microcarriers properties on MSCs proliferation and differentiation potential maintenance should be *** this study,Konjac glucomannan(KGM)microcarriers with a wide range of rigidity from 0.2 MPa to 10 MPa were prepared using water-in-oil emulsion *** was found that the microcarriers rigidity had great influence on MSCs by regulating cell spreading *** proliferation and good differentiation potential maintenance of MSCs were achieved on the intermediate rigidity about 2.51±0.65 MPa with the faster spreading rate of *** a result,MSCs on 2.51±0.65 MPa KGM microcarriers proliferated about 27 times,which was 1.7 times as much as MSCs cultured on the commercial microcarriers *** differentiation potential was also improved about 3.2 times compared to ***,it is indispensable to regulate microcarriers rigidity,especially for application of MSCs.

关键词： MSCs Proliferation Differentiation potential Rigidity Spreading

Control synthesis for polynomial nonlinear systems and application in attitude control

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第6期9卷 833-839页

作者： Chang-fei tong Hui ZHANG You-xian SUN Institute of Industrial Process Control Zhejiang University Hangzhou 310027 China

A method for positive polynomial validation based on polynomial decomposition is proposed to deal with control synthesis problems. Detailed algorithms for decomposition are given which mainly consider how to convert coefficients of a polynomial to a matrix with free variables. Then, the positivity of a polynomial is checked by the decomposed matrix with semidefinite programming solvers. A nonlinear control law is presented for single input polynomial systems based on the Lyapunov stability theorem. The control synthesis method is advanced to multi-input systems further. An application in attitude control is finally presented. The proposed control law achieves effective performance as illustrated by the numerical example.

关键词： Nonlinear control Attitude control Polynomial systems

Cyclocarya cf. paliurus （Batal.） Iljinskaja （Juglandaceae） from the Hunchun Formation （Eocene）, Jilin Province, China

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Journal of Integrative Plant Biology 2005年第11期47卷 1281-1287页

作者： tong-Xing SUN Albert G. ABLAEV Yu-fei WANG Cheng-Sen li Institute of Botany the Chinese Academy of Sciences Beijing 100093 China School of life Sciences Laiyang Agricultural College Laiyang 265200 China Pacific Oceanological Institute Russian Academy of Sciences Vladivostok 600041 Russia Beijing Museum of Natural History Beijing 100050 China

The leaflet architecture of Cyclocarya cf. paliurus （Batal.） Iljinskaja from the Hunchun Formation （Middle Eocene） shows similarity to that of modem C. paliurus （Batal.） Iljinskaja and the specimen is the oldest fossil record in Europe and Asia. The distributions of C. cf. paliurus and other fossil records, such as Glyptostrobus, Metasequoia, Nyssa, and liquidambar, in Hunchun flora show that it would have been a warmer-temperature to subtropical climate in Hunchun District during the Eocene period.

关键词： China Cyclocarya cf. paliurus Eocene Juglandaceae.