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Ruin Probabilities for a Risk Model with Two Classes of Claims

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Acta Mathematica Sinica,English Series 2010年第9期26卷 1749-1760页

作者： tong Ling lv Jun Yi GUO Xin ZHANG Department of Mathematics China Agricultural University Beijing 100083 P. R. China School of Mathematical Sciences Nankai University Tianjin 300071 P. R. China

In this paper we consider a risk model with two kinds of claims, whose claims number processes are Poisson process and ordinary renewal process respectively. For this model, the surplus process is not Markovian, however, it can be Markovianized by introducing a supplementary process, We prove the Markov property of the related vector processes. Because such obtained processes belong to the class of the so-called piecewise-deterministic Markov process, the extended infinitesimal generator is derived, exponential martingale for the risk process is studied. The exponential bound of ruin probability in iafinite time horizon is obtained.

关键词： Markov vector process piecewise-deterministic Markov process (PDMP) infinitesimal generator exponential martingale ruin probability

Multi-endpoint assays reveal more severe toxicity induced by chloraminated effluent organic matter than chloraminated natural organic matter

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Journal of Environmental Sciences 2024年第1期135卷 310-317页

作者： Hai-Yan Wang De-Xiu Wu Ye Du Xiao-tong lv Qian-Yuan Wu State Key Laboratory of Environmental Criteria and Risk Assessment Chinese Research Academy of Environmental SciencesBeijing 100012China Environmental Protection Key Laboratory of Microorganism Application and Risk Control Guangdong Provincial Engineering Research Center for Urban Water Recycling and Environmental SafetyTsinghua Shenzhen International Graduate SchoolTsinghua UniversityShenzhen 518055China College of Architecture and Environment Sichuan UniversityChengdu 610000China

Disinfection by chloramination produces toxic byproducts and the difference in toxicity of reclaimed and drinking water treated by chloramination remains *** study investigated cytotoxic effects at the same concentrations of dissolved organic matter and showed that chloraminated effluent organic matter(EfOM)induced 1.7 times higher cytotoxicity than chloraminated natural organic matter(NOM)applied to simulate drinking *** EfOM induced more reactive nitrogen species than chloraminated NOM,and chloraminated EfOM and NOM induced similar and higher levels of reactive oxygen species than the negative control,***,intracellular macromolecule damage indicated by DNA/RNA damage marker 8–hydroxy-(deoxy)guanosine and the intracellular protein carbonyl concentration induced by chloraminated EfOM was higher and slightly more than that induced by chloraminated NOM,*** data were consistent with the effects on cell physiological *** cycle arrest mainly occurred in G2 phase by chloraminated EfOM and *** apoptotic cells,which could return to normal,increased upon exposure to high concentrations of chloraminated EfOM and ***,necrotic cells were significantly increased from 0.5%to 2.5%when the concentration increased from 20-to 60-fold chloraminated EfOM,but were not obviously changed by chloraminated *** results indicated that the comprehensive intracellular changes induced by toxic substances in chloraminated EfOM were more irreversible and induced more cell death than chloraminated NOM.

关键词： Cytotoxicity Intracellular active nitrogen/oxygen Intracellular oxidative damage Cell necrosis Reclaimed water

Formation and control of disinfection byproducts and toxicity during reclaimed water chlorination： A review

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Journal of Environmental Sciences 2017年第8期29卷 51-63页

作者： Ye Du Xiao-tong lv Qian-Yuan Wu Da-Yin Zhang Yu-Ting Zhou Lu Peng Hong-Ying Hu Environmental Simulation and Pollution Control State Key Joint Laboratory State Environmental Protection Key Laboratory of Microorganism Application and Risk Control (SMARC) School of Environment Tsinghua University Beijing 100084 China Key Laboratory of Microorganism Application and Risk Control of Shenzhen Graduate School at Shenzhen Tsinghua University Shenzhen 518055 China Shenzhen Environmental Science and New Energy Technology Engineering Laboratory Tsinghua-Berkeley Shenzhen Institute Shenzhen518055 China

Chlorination is essential to the safety of reclaimed water; however, this process leads to concern regarding the formation of disinfection byproducts（DBPs） and toxicity. This study reviewed the formation and control strategies for DBPs and toxicity in reclaimed water during *** regulated and emerging DBPs have been frequently detected in reclaimed water during chlorination at a higher level than those in drinking water, indicating they pose a greater risk to humans. Luminescent bacteria and Daphnia magna acute toxicity, anti-estrogenic activity and cytotoxicity generally increased after chlorination because of the formation of DBPs. Genotoxicity by umu-test and estrogenic activity were decreased after chlorination because of destruction of toxic chemicals. During chlorination, water quality significantly impacted changes in *** tended to attenuate toxicity changes by reacting with chlorine to form chloramine,while bromide tended to aggravate toxicity changes by forming hypobromous acid. During pretreatment by ozonation and coagulation, disinfection byproduct formation potential（DBPFP）and toxicity formation potential（TFP） occasionally increase, which is accompanied by DOC removal; thus, the decrease of DOC was limited to indicate the decrease of DBPFP and TFP. It is more important to eliminate the key fraction of precursors such as hydrophobic acid and hydrophilic neutrals. During chlorination, toxicities can increase with the increasing chlorine dose and contact time. To control the excessive toxicity formation, a relatively low chlorine dose and short contact time were required. Quenching chlorine residual with reductive reagents also effectively abated the formation of toxic compounds.

关键词： Reclaimed water Chlorination Disinfection byproducts Toxicity Precursor

High critical current density in Li_(6.4)La_(3)Zr_(1.4)Ta_(0.6)O_(12) electrolyte via interfacial engineering with complex hydride

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Rare Metals 2024年第2期43卷 692-701页

作者： Ying-tong lv Teng-Fei Zhang Zhao-tong Hu Guang-Lin Xia Ze-Ya Huang Zhen-Hua Liu Li-Hua Que Cai-Ting Yuan Fang-Qin Guo Takayuki Ichikawa Xue-Bin Yu College of Materials Science and Technology Nanjing University of Aeronautics and AstronauticsNanjing210016China Centre for Hydrogenergy College of Materials Science and TechnologyNanjing University of Aeronautics and AstronauticsNanjing210016China Department of Materials Science Fudan UniversityShanghai200433China Graduate School of Advanced Science and Engineering Hiroshima University1-4-1 KagamiyamaHigashi-Hiroshima739-8527Japan

Garnet-type solid-state batteries(SSBs)are considered to be one of the most promising candidates to realize next-generation lithium metal batteries with high energy density and ***,the dendrite-induced short-circuit and the poor interfacial contact impeded the practical ***,interface engineering to achieve low interfacial resistance without high temperature calcination was developed,which Li_(6.4)La_(3)Zr_(1.4)Ta_(0.6)O_(12)(LLZTO)was simply coated with complex hydride(Li_(4)(BH_(4))_(3)I(3L1L))in various mass ratios n(Li_(4)(BH_(4))_(3)I)-(100−n)LLZTO(10≤n≤40).The interfacial conductivity increases by more than three orders of magnitude from 8.29×10^(−6)S·cm^(−1)to 1.10×10^(−2)S·cm^(−1).Symmetric Li cells exhibit a high critical current density(CCD)of 4.0 mA·cm^(−2) and an excellent cycling stability for 200 h at 4.0 mA·cm^(−2).SSBs with polymeric sulfur-polyacrylonitrile(SPAN)cathode achieve a high discharge capacity of 1149 mAh·g^(−1) with a capacity retention of 91%after 100 cycles(0.2 C).This attempt guides a simple yet efficient strategy for obtaining a stable Li/LLZTO interface,which would promote the development of solid-state batteries.

关键词： Hydrides Li_(6.4)La_(3)Zr_(1.4)Ta_(0.6)O_(12)(LLZTO) Critical current density Solid-state electrolytes(SSEs) Lithium-sulfur batteries

Temporospatial inhibition of Erk signaling is required for lymphatic valve formation

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Signal Transduction and Targeted Therapy 2023年第10期8卷 4850-4866页

作者： Yaping Meng tong lv Junfeng Zhang Weimin Shen Lifang Li Yaqi Li Xin Liu Xing Lei Xuguang Lin Hanfang Xu Anming Meng Shunji Jia State Key Laboratory of Membrane Biology Tsinghua-Peking Center for Life SciencesSchool of Life SciencesTsinghua UniversityBejing 100084China Guangzhou Laboratory Guangzhou 510320 Guangdong ProvinceChina State Key Laboratory of Molecular Developmental Biology Institute of Genetics and Developmental BiologyChinese Academy of SciencesBeijing 100101China

Intraluminal lymphatic valves(lvs)and lymphovenous valves(lvs)are critical to ensure the unidirectional flow of lymphatic *** abnormalities in these valves always cause lymph or blood reflux,and result in lymphedema.

关键词： lymphatic Morphological edema

网格化治理结构优化路径探讨——以结构功能主义为视角

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北京社会科学 2021年第4期 106-115页

作者：吕童中国矿业大学公共管理学院徐州221000

作为国家治理体系的子系统,社会治理体系在实现保持社会稳定、维护国家安全等治理目标的同时,具有促进不同治理体系整合的功能,而功能作为结构的体现,其释放取决于相应结构的支撑。当前网格化治理模式在治理结构层面,强调治理主体共同... 详细信息

作为国家治理体系的子系统,社会治理体系在实现保持社会稳定、维护国家安全等治理目标的同时,具有促进不同治理体系整合的功能,而功能作为结构的体现,其释放取决于相应结构的支撑。当前网格化治理模式在治理结构层面,强调治理主体共同在场下的位置权变调整;而在其功能输出层面,存在治理主体整合功能失调、公众需求满足严重依赖政府、治理目标缺乏统合以及规范引导相对薄弱等问题。这可以通过精准化权变治理主体位置、打造网络化权力运行格局、拓宽治理主体间对话渠道以及完善规范体系建设等结构优化路径,使网格化治理输出功能得到强化。

关键词：结构功能主义社会治理结构网格化治理

Current progress of computational modeling for guiding clinical atrial fibrillation ablation

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2021年第10期22卷 805-817页

作者： Zhenghong WU Yunlong LIU lv tong Diandian DONG Dongdong DENG Ling XIA College of Biomedical Engineering&Instrument Science Zhejiang UniversityHangzhou 310027China School of Biomedical Engineering Dalian University of TechnologyDalian 116024China

Atrial fibrillation(AF)is one of the most common arrhythmias,associated with high morbidity,mortality,and healthcare costs,and it places a significant burden on both individuals and ***-arrhythmic drugs are the most commonly used strategy for treating ***,drug therapy faces challenges because of its limited efficacy and potential side *** ablation is widely used as an alternative treatment for ***,because the mechanism of AF is not fully understood,the recurrence rate after ablation remains *** addition,the outcomes of ablation can vary significantly between medical institutions and patients,especially for persistent ***,the issue of which ablation strategy is optimal is still far from *** modeling has the advantages of repeatable operation,low cost,freedom from risk,and complete control,and is a useful tool for not only predicting the results of different ablation strategies on the same model but also finding optimal personalized ablation targets for clinical reference and even *** review summarizes three-dimensional computational modeling simulations of catheter ablation for AF,from the early-stage attempts such as Maze III or circumferential pulmonary vein isolation to the latest advances based on personalized substrate-guided ***,we summarize current developments and challenges and provide our perspectives and suggestions for future directions.

关键词： Atrial fibrillation Catheter ablation Computational modeling Atrial fibrosis

美国馆藏中共抗战解密史料汇编——西方见证人眼中的敌后根据地

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上海交通大学学报（哲学社会科学版） 2015年第5期23卷 5-15页

作者：吕彤邻上海交通大学人文学院上海200240

在八年抗战中,以美国为首的部分西方人士曾经冲破日军与国民党政府的封锁,到延安以及华北敌后根据地考察中共抗日的状况。这些人有记者、民间人士、特别是战争后期美军观察组的情报人员。他们在美国档案馆留下了大批有关史中共游击战的... 详细信息

在八年抗战中,以美国为首的部分西方人士曾经冲破日军与国民党政府的封锁,到延安以及华北敌后根据地考察中共抗日的状况。这些人有记者、民间人士、特别是战争后期美军观察组的情报人员。他们在美国档案馆留下了大批有关史中共游击战的历史文献。出于对于美英系统的同盟国反轴心国的共同目标,这些意识形态、政治背景、职业各异的西方人士,对中共抗日尽可能地作了客观描述。站在第三者的立场,这些超脱国共两党之争的即时报道为我们的敌后抗战留下了珍贵记载。

关键词：游击战西方记者敌后根据地延安美军观察组中共国民党

Fully Automatic Scar Segmentation for Late Gadolinium Enhancement MRI Images in Left Ventricle with Myocardial Infarction

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Current Medical Science 2021年第2期41卷 398-404页

作者： Zheng-hong WU Li-ping SUN Yun-long LIU Dian-dian DONG lv tong Dong-dong DENG Yi HE Hui WANG Yi-bo SUN Jian-zeng DONG Ling XIA College of Biomedical Engineering&Instrument Science Zhejiang UniversiryHangzhou 310027China Department of Cardiology the First Affiliated Hospital of Zhengzhou UniversiryZhengzhou 450052China School of Biomedical Engineering Dalian University of TechnologyDalian 116024China Department of Cardiology Beijing Anzhen HospitalCapital Medical University and National Clinical Research Center for Cardiovascular DiseasesBeijing 100029China Department of Cardiology Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China

Numerous methods have been published to segment the infarct tissue in theleft ventricle, most of them either need manual work, post-processing, or suffer from poorreproducibility. We proposed an automatic segmentation method for segmenting the infarct tissue irleft ventricle with myocardial infarction. Cardiac images of a total of 60 diseased hearts (55 humanhearts and 5 porcine hearts) were used in this study. The epicardial and endocardial boundariesof the ventricles in every 2D slice of the cardiac magnetic resonance with late gadoliniumenhancement images were manually segmented. The subsequent pipeline of infarct tissuesegmentation is fully automatic. The segmentation results with the automatic algorithm proposed inthis paper were compared to the consensus ground truth. The median of Dice overlap between ourautomatic method and the consensus ground truth is 0.79. We also compared the automatic methodwith the consensus ground truth using different image sources from diferent centers with diferentscan parameters and different scan machines. The results showed that the Dice overlap with thepublic dataset was 0.83, and the overall Dice overlap was 0.79. The results show that our method isrobust with respect to different MRI image sources, which were scanned by different centers withdifferent image collection parameters. The segmentation accuracy we obtained is comparable toor better than that of the conventional semi-automatic methods. Our segmentation method may beuseful for processing large amount of dataset in clinic.

关键词： myocardial infarction cardiac magnetic resonance with late gadolinium enhancement automatic scar segmentation