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Defence Technology（防务技术） 2024年第2期32卷 209-221页

作者： Mingming Wang linfang Qian Guangsong Chen tong lin Junfei Shi Shijie Zhou Nanjing University of Science and Technology Nanjing 210094JiangsuChina Northwest Institute of Mechanical and Electrical Engineering Xianyang 712099ShaanxiChina Nanjing Vocational University of Industry Technology Nanjing 210023JiangsuChina

This paper proposed an efficient research method for high-dimensional uncertainty quantification of projectile motion in the barrel of a truck-mounted ***,the dynamic model of projectile motion is established considering the flexible deformation of the barrel and the interaction between the projectile and the ***,the accuracy of the dynamic model is verified based on the external ballistic projectile attitude test ***,the probability density evolution method(PDEM)is developed to high-dimensional uncertainty quantification of projectile *** engineering example highlights the results of the proposed method are consistent with the results obtained by the Monte Carlo Simulation(MCS).Finally,the influence of parameter uncertainty on the projectile disturbance at muzzle under different working conditions is *** results show that the disturbance of the pitch angular,pitch angular velocity and pitch angular of velocity decreases with the increase of launching angle,and the random parameter ranges of both the projectile and coupling model have similar influence on the disturbance of projectile angular motion at muzzle.

关键词： Truck-mounted howitzer Projectile motion Uncertainty quantification Probability density evolution method

Recent advances in age-related metabolic dysfunction-associated steatotic liver disease

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World Journal of Gastroenterology 2024年第7期30卷 652-662页

作者： Qian-Jun He Yi-Fei Li ling-tong Zhao Chun-tong lin Chun-Yan Yu Dan Wang College of Basic Medicine Beihua UniversityJilin 132013Jilin ProvinceChina Department of Traumatic Surgery Jilin Central HospitalJilin 132001Jilin ProvinceChina

Metabolic dysfunction-associated steatotic liver disease(MASLD)affects approximately 25%of the world's population and has become a leading cause of chronic liver *** recent years,an increasing amount of data suggests that MASLD is associated with *** the population ages,age-related MASLD will become a major global health *** an aging will become a new approach to the treatment of *** paper reviews the current studies on the role of aging-related factors and therapeutic targets in MASLD,including:Oxidative stress,autophagy,mitochondrial homeostasis,bile acid metabolism homeostasis,and *** aim is to identify effective therapeutic targets for age-related MASLD and its progression.

关键词： Metabolic dysfunction-associated steatotic liver disease Aging Mitochondrial homeostasis Bile acid homeostasis Dysbiosis

Reservoir characteristics and controlling factor of tight sandstone in Shuixigou Group in Taibei depression,Turpan-Hami basin

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Energy Geoscience 2024年第2期5卷 70-80页

作者： tong lin Xuan Chen Fan Yang Hongguang Gou Mingyu Liu Runze Yang PetroChina Research Institute of Petroleum Exploration&Development Beijing100083China Research Institute of Exploration&Development PetroChina Tuha Oilfield Company HamiXinjiang839009China China University of Geosciences(Beijing) Beijing100083China

The positive structure belts surrounding the Taibei Sag,Turpan-Hami Basin,have been the main targets for oil and gas exploration for years and are now left with remaining resources scattering in reservoirs adjacent to source rocks in the sag,where the Shuixigou Group with substantial oil and gas potential constitutes the primary focus for near-source ***,characterization of development and key controlling factors of reservoir space becomes a must for future exploration in the *** study investigates the development traits,genesis,and controlling factors of the Xishanyao and Sangonghe formations in the Shengbei and Qiudong Sub-sags of the Taibei Sag with techniques such as cast thin-section observation,porosity and permeability tests,high-pressure mercury injection,and saturation fluid NMR analysis of reservoir *** findings reveal that the Shuixigou Group in the Taibei Sag consists of lithic *** in the group are mostly poor in terms of physical properties,with undeveloped primary pores dominated by intergranular dissolved pores as a result of a strong *** analysis of key controlling factors of the Sangonghe Formation reveals significant distinctions in sandstone particle size,sand body thickness,genesis and distribution,provenance location,and source rock type between the Qiudong area and Shengbei ***,the coal seams of the Xishanyao Formation exhibit heightened development with shallower burial depth and lower maturity compared to those of the Sangonghe ***,this environment fosters the formation of organic acids,which have a stronger dissolution effect on minerals to develop secondary dissolution pores,and ultimately resulting in better reservoir physical ***,the reservoirs within the Qiudong area of the Taibei Sag demonstrate superior characteristics compared to those in the Shengbei ***,the reservoir physical properties of the Xishanyao For

关键词： Intergranular dissolved pore Organic acid dissolution Secondary dissolution pore Tight sandstone Shuixigou group Turpan-Hami basin

Characteristics and Risk Factors for Pediatric Sepsis

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Current Medical Science 2024年第3期44卷 648-656页

作者： Yong-bing ZHU tong-lin LIU Qi DAI Shu-fan LIU Peng XIONG Hao HUANG Yi YUAN Tian-nan ZHANG Yu CHEN Department of Pediatric Intensive Care Unit Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China

Objective Sepsis is considered a major cause of health loss in children and had high mortality and ***,there is no reliable model for predicting the prognosis of pediatric patients with *** study aimed to analyze the clinical characteristics of sepsis in children and assess the risk factors associated with poor prognosis in pediatric sepsis patients to identify timely interventions and improve their *** This study analyzed the clinical indicators and laboratory results of septic patients hospitalized in the Pediatric Intensive Care Unit of tongji Hospital,tongji Medical College,Huazhong University of Science and Technology,China,from January 1,2019,to December 31,*** factors for sepsis were identified by logistic regression *** A total of 355 children with sepsis were enrolled,with 333 children(93.8%)in the good prognosis group,and 22 children(6.2%)in the poor prognosis *** them,there were 255 patients(71.8%)in the sepsis group,and 100 patients(28.2%)in the severe sepsis *** length of hospital stay in the poor prognosis group was longer than that in the good prognosis group(P0.05),and the platelet(PLT),albumin(ALB),and hemoglobin(Hb)levels were lower in the poor prognosis group(P<0.01).The IL-8 levels in the severe sepsis group were higher than those in the sepsis group(P<0.05).Multiple logistic regression analysis suggested that lower Hb levels,ALB levels,peak PLT counts,and higher IL-1βlevels were independent risk factors for poor prognosis in children with *** Lower Hb,ALB,and PLT counts and elevated IL-1βare independent risk factors for poor prognosis in children with sepsis.

关键词： pediatric sepsis inflammation severity prognosis risk factors

Reform of Teaching Practice of Modern Instrumental Analysis in Biotechnology Programs

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Agricultural Biotechnology 2024年第3期13卷 93-95页

作者： Kun TANG tong lin Zhenxia SHI Jie QIAO Chunyan XIE Lixin DU College of Life Science Langfang Normal UniversityLangfang 065000China

Through the online and offline practical reform of the Modern Instrumental Analysis course of biotechnology majors from teaching content,teaching method,teaching demonstration to teaching effect,the traditional single offline lecture is transformed into diversified and interactive modern *** practical reform enriches and optimizes the course content,perfects and improves the course assessment system,and improves the teaching *** achieves the student-centered and application-oriented teaching goal,and also provides reference for further cultivating high-quality applied talents.

关键词： Modern instrumental analysis Biotechnology Online and offline Reform of teaching

IL-31及其受体在皮肤病发生及治疗中的研究进展

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中国皮肤性病学杂志 2024年第6期38卷 696-699,704页

作者：孙小洁林彤北京协和医学院/中国医学科学院/皮肤病医院/皮肤病研究所激光科江苏南京210042

IL-31是一种神经免疫因子,可由Th2型淋巴细胞、单核/巨噬细胞、树突状细胞、肥大细胞、嗜酸性粒细胞、嗜碱性粒细胞等细胞分泌;主要通过与IL-31受体A(IL-31RA)和瘤抑素M受体β(OSMRβ)偶联形成的异二聚体受体复合体结合,发挥相应的生物... 详细信息

IL-31是一种神经免疫因子,可由Th2型淋巴细胞、单核/巨噬细胞、树突状细胞、肥大细胞、嗜酸性粒细胞、嗜碱性粒细胞等细胞分泌;主要通过与IL-31受体A(IL-31RA)和瘤抑素M受体β(OSMRβ)偶联形成的异二聚体受体复合体结合,发挥相应的生物学作用。近年来,对于IL-31及其受体引发相关疾病的机制研究取得了一些进展。研究表明,一方面,IL-31通过激活瞬时受体电位香草酸受体1(TRPV1)、瞬时受体电位受体A1(TRPA1)上调神经元兴奋性等方式参与瘙痒形成;另一方面,通过激活JAK/STAT、PI3K/AKT等信号通路,招募多种细胞因子促进炎症形成。IL-31参与特应性皮炎、结节性痒疹、大疱性类天疱疮等多种皮肤疾病的发生发展。同时针对IL-31受体的生物制剂奈莫利珠单抗,已经批准上市,用于辅助治疗当前治疗无效的特应性皮炎的瘙痒。本文主要围绕IL-31及其受体在皮肤科疾病发生及治疗中取得的相关进展进行综述。

关键词：白介素31 白介素31受体α 皮肤疾病发生机制治疗

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改进YOLOX的自动驾驶场景目标检测算法

计算机工程与应用 2024年第12期60卷 225-233页

作者：陈商盈倪受东童林南京工业大学机械与动力工程学院南京211800

针对原始YOLOX在自动驾驶场景中易出现小目标的误检及漏检问题,提出一种改进YOLOX网络模型的检测方法。增加一个检测头,显著提高了小目标的检测精度。用更快的空间金字塔池化(spatial pyramid poolingfast,SPPF)替代传统的空间金字塔池... 详细信息

针对原始YOLOX在自动驾驶场景中易出现小目标的误检及漏检问题,提出一种改进YOLOX网络模型的检测方法。增加一个检测头,显著提高了小目标的检测精度。用更快的空间金字塔池化(spatial pyramid poolingfast,SPPF)替代传统的空间金字塔池化(spatial pyramid pooling,SPP)结构,并引入了高效通道注意力机制(efficient channel attention,ECA),以增强模型对复杂背景和小目标的识别能力,有效降低了小目标的漏检率。在网络的neck部分,采用深度可分离的卷积方法,进一步提高了计算效率。基于KITTI数据集,设计了一种新的数据增强技术,提高模型的训练稳定性。实验结果表明,优化后YOLOX算法的小目标平均精度APS和平均召回率AR分别提升了0.20和0.097,在小目标检测上取得了显著进步,并大大降低了漏检率。

关键词：自动驾驶 YOLOX 目标检测注意力机制

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中小学语文教材选用古诗文篇目的版本问题——从《孟子》“斯人”与“是人”之争说起

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图书馆杂志 2024年第6期43卷 124-131页

作者：李明杰林通武汉大学信息管理学院

通过对《孟子》版本源流的梳理,发现诸版本仅有“故天将降大任于是人也”的记载,且“是人”的用法更接近战国时期的文法习惯,而“斯人”之说源自其他文献对《孟子》文本的征引。为了发挥正面导向作用,避免近年频发的古诗文选篇的异文之... 详细信息

通过对《孟子》版本源流的梳理,发现诸版本仅有“故天将降大任于是人也”的记载,且“是人”的用法更接近战国时期的文法习惯,而“斯人”之说源自其他文献对《孟子》文本的征引。为了发挥正面导向作用,避免近年频发的古诗文选篇的异文之争,中小学语文教材的编辑出版工作亟待进一步优化。不仅要充分利用影印本、整理本等优质文献资源进行版本源流的梳理和异同的比较,从中甄选出最可靠的文本,而且应当标明所选版本与典型异文情况,向中小学生普及文献学常识,传递正确和理性的版本观念。

关键词：教材出版中小学语文古诗文版本《孟子》

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古籍的数字赋能与增值利用——“数智时代的古籍活化与利用”高端论坛述评

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图书情报知识 2024年第2期41卷 81-86页

作者：林通郑翔李明杰武汉大学信息管理学院武汉430072 武汉大学文化遗产智能计算实验室武汉430072

2023年4月21-23日,武汉大学文化遗产智能计算实验室联合武汉大学大数据研究院、文学院、古籍所、信息管理学院,以及新闻出版署语义出版与知识服务实验室等单位举办的“数智时代的古籍活化与利用”高端论坛在武汉大学隆重召开。来自国内... 详细信息

2023年4月21-23日,武汉大学文化遗产智能计算实验室联合武汉大学大数据研究院、文学院、古籍所、信息管理学院,以及新闻出版署语义出版与知识服务实验室等单位举办的“数智时代的古籍活化与利用”高端论坛在武汉大学隆重召开。来自国内高校、图书馆和出版社等领域的专家学者齐聚一堂。本次论坛旨在贯彻落实中共中央办公厅、国务院办公厅《关于推进新时代古籍工作的意见》的文件精神,推进古籍抢救性保护、整理研究、编辑出版、普及推广和人才培养等工作。围绕数智时代的古籍整理与研究、古籍活化利用的前沿理论与先进技术、数智时代的古籍出版与再造三大主题,与会专家进行了深入的对话和交流。

关键词：信息管理学院语义出版前沿理论智能计算中共中央办公厅高端论坛抢救性保护人才培养

远程程控在心脏置入型电子器械术后随访中的可行性和安全性初探

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中华心血管病杂志 2024年第6期52卷 684-689页

作者：龙宇童琳秦淑娟李锦熊诗强蔡琳西南交通大学附属医院、成都市第三人民医院心内科成都610031

目的探索基于5G云技术支持平台的远程程控技术在心脏置入型电子器械(CIED)术后随访中的可行性和安全性。方法本研究为多中心横断面研究。选取2021年6至10月在四川省12家暂缺随访专员的综合医院的CIED置入患者,由成都市第三人民医院远程... 详细信息

目的探索基于5G云技术支持平台的远程程控技术在心脏置入型电子器械(CIED)术后随访中的可行性和安全性。方法本研究为多中心横断面研究。选取2021年6至10月在四川省12家暂缺随访专员的综合医院的CIED置入患者,由成都市第三人民医院远程随访中心的随访专员通过5G云技术支持平台对患者器械进行实时远程检查和远程程控。收集患者的基线资料、器械报警事件、再程控事件、不良反应及满意度问卷调查结果。结果共纳入195例CIED置入患者,年龄(72.5±11.3)岁,男性103例(52.6%),所有患者均成功完成远程检查和程控,用时(5.8±4.0)min。根据随访结果,91例患者的CIED需要再程控,累计参数调整104次。所有程控过程通信情况无异常,患者未发生任何不良事件。满意度问卷调查显示,97.9%(191/195)的患者信任或比较信任远程随访,86.7%(169/195)的患者愿意选择远程随访模式进行设备管理。结论基于5G云技术支持平台的远程程控技术在CIED患者术后随访中的临床应用可能是可行、安全的。

关键词：远程医学心脏置入型电子器械远程程控远程监测 5G云技术支持平台随访安全性可行性