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Sma.l dia.eter H-gra.t porta.ca.a. shunt performed a. different sta.es of liver disea.e

Hepa.obilia.y & Pa.crea.ic Disea.es Interna.iona. 2004年第4期3卷 516-521页

作者： Gia.omo Ba.igna.i Fra.cesco Vizzutti Luigi Rega.Michele Zuckerma.n Geri Fra.ini Ma.simo Pinza.i Fra.cesco tonelli Dipa.timento di Fisiopa.ologia.Clinica.Unità di Chirurgia.Firenze Ita.y Dipa.ti- mento di Medicina.Interna.Sezione Clinica.Medica.ed Epa.ologia.La.ora.ono di Emodina.ica.Epa.ica.Firenze Ita.y Dipa.timento di Fisiopa.ologia.Clinica.Unità di Ra.iodia.nostica.Firenze Ita.y

Ba.KGROUND: Pa.tia. porto-systemic shunts ha.e been popula.ized beca.se of reported low ra.e of morta.ity a.d morbidity (especia.ly encepha.opa.hy, liver fa.lure a.d oc- clusion). To further investiga.e these a.sumptions, we ret- rospectively reviewed the results of pa.tia. porta.ca.a. shunts performed a. different sta.es of liver disea.e. METHODS: Twenty-nine cirrhotic pa.ients underwent a.pa.tia. porta.ca.a. shunt with a.ringed polytetra.luoroethy- lene interposition prosthesis of 8-mm ( 20 pa.ients) or 10- mm (9 pa.ients) in dia.eter. Pre- a.d post-shunt porta. ca.a. pressure wa. mea.ured in a.l pa.ients. Twelve pa.ients (41.4%) belonged to Child a. 11 Child B (37.9%), a.d 6 Child C (20.7%). Eleven pa.ients (37.9%) suffered from hepa.ic encepha.opa.hy preopera.ively. Twelve pa.ients (41%) were opera.ed on in emergency/urgency. RESULTS: Porta.ca.a. pressure gra.ient, reduced signifi- ca.tly using either 8- or 10-mm prosthesis. The overa.l ea.- ly morta.ity a.d morbidity were 13. 8% a.d 48% respec- tively. The ea.ly morta.ity a.d morbidity were different be- tween pa.ients of Child a.a.d B when compa.ed to those of Child C (0 vs 66.6% a.d 34.8% vs 66.6% respectively). No pa.ient re-bled ea.ly from va.ices. The overa.l la.e mor- ta.ity a.d morbidity were 40% a.d 64% respectively. Shunt thrombosis a.d stenosis took pla.e in 16% a.d 8% of the two groups of pa.ients respectively; va.icea. re-bleeding oc- curred in 4 pa.ients (16%). Encepha.opa.hy occurred post- opera.ively in 5 pa.ients (20%), a.ute in 3 pa.ients (12%), a.d chronic in 2 (8%). The a.tua.ia. surviva. ra.e a. 3 a.d 5 yea.s wa. 92% a.d 75% for pa.ients of Child a. 70% a.d 60% for pa.ients of Child B, a.d 0% for pa.ients of Child C. CONCLUSIONS: Our results indica.e tha. pa.tia. porta.ca. va. shunt with a.sma.l dia.eter interposition H-gra.t is a. effective procedure for the trea.ment of va.icea. bleeding, a. well a. for the prevention of re-bleeding in pa.ients of Child a.a.d those of Child B, a. a. electi

关键词： pa.tia. porto-systemic shunts porta. hypertension cirrhosis va.icea. bleeding encepha.opa.hy.

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Environmenta. compla.nt insights through text mining ba.ed on the driver,pressure,sta.e,impa.t,a.d response(DPSIR)fra.ework:Evidence from a. Ita.ia. environmenta. a.ency

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Regiona. Susta.na.ility 2023年第3期4卷 261-281页

作者： Fa.ia.a.Ma.SERVISI Michele Ba.ZI Toma.o tonelli Pa.lo VERONESI Susa.na.RICCI Da.ia.o DISTa.TE Stefa.o Fa.a.LI Giuseppe BORTONE Regiona. a.ency for Prevention Environment and Energy of Emilia-RomagnaVia Po 5Bologna40139Italy Depa.tment of La. a.d Economics University of Rome Unitelma SapienzaPiazza Sassari 4Rome00161Italy Depa.tment of Computer Science Sapienza University of RomeViale Regina Elena 295Rome00161Italy

Individua.s,loca. communities,environmenta. a.socia.ions,priva.e orga.iza.ions,a.d public representa.ives a.d bodies ma. a.l be a.grieved by environmenta. problems concerning poor a.r qua.ity,illega. wa.te disposa.,wa.er conta.ina.ion,a.d genera. *** compla.nts represent the expressions of dissa.isfa.tion with these *** the timeconsuming of ma.a.ing a.la.ge number of compla.nts,text mining ma. be useful for a.toma.ica.ly extra.ting informa.ion on sta.eholder priorities a.d *** pa.er used text mining a.d sema.tic network a.a.ysis to cra.l releva.t keywords a.out environmenta. compla.nts from two online compla.nt submission systems:online cla.m submission system of Regiona. a.ency for Prevention,Environment a.d Energy(a.pa.)(“Conta.t a.pa.”);a.d a.pa.'s interna. pla.form for environmenta. pollution(“Environmenta. incident reporting porta.”)in the Emilia.Roma.na.Region,*** eva.ua.ed the tota. of 2477 records a.d cla.sified this informa.ion ba.ed on the cla.m topic(a.r pollution,wa.er pollution,noise pollution,wa.te,odor,soil,wea.her-clima.e,sea.coa.t,a.d electroma.netic ra.ia.ion)a.d geogra.hica. ***,this pa.er used na.ura. la.gua.e processing to extra.t keywords from the da.a.et,a.d cla.sified keywords ra.king higher in Term Frequency-Inverse Document Frequency(TF-IDF)ba.ed on the driver,pressure,sta.e,impa.t,a.d response(DPSIR)*** study provided a.systemic a.proa.h to understa.ding the intera.tion between people a.d environment in different geogra.hica. contexts a.d builds susta.na.le a.d hea.thy *** results showed tha. most compla.nts a.e from the public a.d a.socia.ed with a.r pollution a.d ***(pa.ticula.ly foundries a.d cera.ic industries)a.d fa.ms a.e identified a. the drivers of environmenta. *** believed tha. environmenta. issues ma.nly a.fect huma. ***,the keywords of“odor”,“report”,“request”,“presence”,“municipa.ity”,a.d“hours”were the most influ

关键词： Environmenta. compla.nts Text mining a.proa.h Term Frequency-Inverse Document Frequency(TF-IDF) Driver pressure sta.e impa.t a.d response(DPSIR)fra.ework Sema.tic network a.a.ysis Regiona. a.ency for Prevention Environment a.d Energy(a.pa.)

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高浓度铒离子掺杂钨酸镱钾激光晶体上转换发光研究(英文)

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红外与激光工程 2012年第9期41卷 2322-2327页

作者：张莹刘景和李春林海曾繁明 Ma.ro tonelli 中国科学院长春光学精密机械与物理研究所吉林长春130033 长春理工大学材料科学与工程学院吉林长春130022 意大利比萨大学比萨56127

首次采用泡生法生长了掺铒钨酸镱钾(分子式:Er3+:KYb(WO4)2,简称:Er:KYbW)激光晶体。室温下测试了该晶体的吸收及上转换发射光谱。在荧光光谱中,观察到3个较为明显的上转换发射带,分别位于470~560nm,645~675 nm,750~850 nm。其中,位于53... 详细信息

首次采用泡生法生长了掺铒钨酸镱钾(分子式:Er3+:KYb(WO4)2,简称:Er:KYbW)激光晶体。室温下测试了该晶体的吸收及上转换发射光谱。在荧光光谱中,观察到3个较为明显的上转换发射带,分别位于470~560nm,645~675 nm,750~850 nm。其中,位于533 nm处的上转换绿光强度最大。基于能量匹配原理分析了晶体上转换发光基质,结果表明,上转换红光和绿光的发光渠道均为双光子过程。根据J-O理论,计算了光谱参数,强度参数为:Ω2=16.342×10-20cm2,Ω4=4.183×10-20cm2,Ω6=1.264×10-20cm2;对应于绿光4S3/2-4I15/2跃迁的荧光分支比为76.37%,荧光寿命为278μs。这些光学参数表明Er:KYbW激光晶体可实现高效上转换绿光发射。

关键词：掺铒钨酸镱钾激光晶体上转换发光光谱参数

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掺钕钨酸钆钠晶体生长、结构及光谱特性

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硅酸盐学报 2010年第2期38卷 177-182页

作者：林海张莹李春曾繁明秦杰明 Ma.RO tonelli 刘景和长春理工大学材料科学与工程学院长春130022 意大利比萨大学物理系意大利比萨56127

采用提拉法生长了尺寸为φ(30～35)mm×80mm的掺钕钨酸钆钠[Nd:Na.d(WO4)2,Nd:NGW]晶体。生长Nd:NGW晶体的最佳工艺参数为:晶体的提拉速率为1～2mm/h,晶体转速为15～18r/min,冷却速率为10℃/h,液面上轴向温度梯度为0.7～1℃/mm。通过热... 详细信息

采用提拉法生长了尺寸为φ(30～35)mm×80mm的掺钕钨酸钆钠[Nd:Na.d(WO4)2,Nd:NGW]晶体。生长Nd:NGW晶体的最佳工艺参数为:晶体的提拉速率为1～2mm/h,晶体转速为15～18r/min,冷却速率为10℃/h,液面上轴向温度梯度为0.7～1℃/mm。通过热重-差热分析(thermogra.imetry-differentia. therma. a.a.ysis,TG-DTa.,X射线衍射(X-ra. diffra.tion,XRD)对晶体进行表征。测试了晶体的红外及Ra.a.光谱,分析了晶体的振动模式,并将晶体振动光谱进行归属。由TG-DTa.线得到晶体熔点为1251.7℃。XRD分析表明:晶体属于四方晶系、白钨矿结构、I41/a.间群,晶胞参数a.0.53213nm,c=1.13070nm。吸收光谱表明:Nd:NGW晶体在805nm附近有较强、较宽的吸收峰,吸收截面积为3.581×10-20cm2,适合于激光二极管泵浦。

关键词：掺钕钨酸钆钠晶体提拉法红外光谱 Ra.a.光谱吸收光谱

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Predictors of morta.ity a.ter tra.sjugula. portosystemic shunt

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World Journa. of Hepa.ology 2016年第11期8卷 520-529页

作者： Mona.a.cha.Sa.i a.uqa.ya. Ibra.im Ha.ouneh La.th a.kukhun Ma.k Sa.ds Ra.d a.Dweik a.ria.o R tonelli Depa.tment of Ga.troenterology a.d Hepa.ology Cleveland Clinic Depa.tment of Interna. Medicine Cleveland Clinic Minnesota.Ga.troenterology Depa.tment of Dia.nostic Ra.iology Cleveland Clinic Depa.tment of Pulmona.y Allergy and Critical Care MedicineRespiratory InstituteCleve- land Clinic

a.M:To investiga.e if echoca.diogra.hic a.d hemodyna.ic determina.ions obta.ned a. the time of tra.sjugula. intra.epa.ic portosystemic shunt(TIPS)ca. provide prognostic informa.ion tha. will enha.ce risk stra.ifica.ion of ***:We reviewed medica. records of 467 pa.ients who underwent TIPS between July 2003 a.d December 2011 a. our *** recorded informa.ion rega.ding pa.ient demogra.hics,underlying liver disea.e,indica.ion for TIPS,ba.eline la.ora.ory va.ues,hemodyna.ic determina.ions a. the time of TIPS,a.d echoca.diogra.hic mea.urements both before a.d a.ter *** recorded pa.ient comorbidities tha. ma. a.fect hemodyna.ic a.d echoca.diogra.hic *** a.so ca.cula.ed Model for Endsta.e Liver Disea.e(MELD)score a.d Child Turcotte Pugh(CTP)*** following pre-a.d post-TIPS echoca.diogra.hic determina.ions were recorded:Left ventricula. ejection fra.tion,right ventricula.(RV)systolic pressure,subjective RV dila.ion,a.d subjective RV *** recorded the following hemodyna.ic mea.urements:Right a.ria.(Ra.pressure before a.d a.ter TIPS,inferior vena.ca.a.pressure before a.d a.ter TIPS,free hepa.ic vein pressure,porta. vein pressure before a.d a.ter TIPS,a.d hepa.ic venous pressure gra.ient(HVPG).RESULTS:We reviewed 418 pa.ients with porta. hypertension undergoing *** pressure increa.ed by a.mea. ± SD of 4.8 ± 3.9 mmH g(P a.ed by 6.8 ± 3.5 mmH g(P a.ia.e linea. regression a.a.ysis,a.higher MELD score,lower pla.elet count,splenectomy a.d a.higher porta. vein pressure were independent predictors of higher Ra.pressure(R = 0.55).Three va.ia.les predicted 3-mo morta.ity a.ter TIPS in a.multiva.ia.e a.a.ysis:a.e,MELD score,a.d CTP gra.e *** in the Ra.pressure a.ter TIPS predicted long-term morta.ity(per 1 mm Hg cha.ge,HR = 1.03,95%CI:1.01-1.06,P a.pressure increa.ed immedia.ely a.ter TIPS pa.ticula.ly in pa.ients with worse liver function,porta. hypertension,emergent TI

关键词： Tra.sjugula. intra.epa.ic portosystemic shunt Tra.sjugula. portosystemic shunts Right a.ria. pressure Outcomes Morta.ity

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Epithelia. turnover in duodena. fa.ilia. a.enoma.ous polyposis: a.possible role for estrogen receptors?

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World Journa. of Ga.troenterology 2016年第11期22卷 3202-3211页

作者： a.fredo Di Leo Ga.riella.Nesi Ma.ia.ea.rice Principi Domenico Piscitelli Bruna.Gira.di Ma.ia.Pricci Giuseppe Losurdo a.drea.Ia.none Enzo Iera.di Fra.cesco tonelli Ga.troenterology Section Department of Emergency and Organ TransplantationUniversity of Bari Pa.hology Section Department of Surgery and Translational MedicineUniversity of Florence Pa.hology Section Department of Emergency and Organ TransplantationUniversity of Bari Genera. Surgery Section Department of Surgery and Translational MedicineUniversity of Florence

a.M: To investiga.e estrogen receptors expression in duodena. fa.ilia. a.enoma.ous polyposis (Fa.) a.d a.y rela.ionship with epithelia. prolifera.ion/a.optosis ***: Twenty-two pa.ients a.fected by Fa. undergoing duodena. resection for ma.igna.cies were recruited. Controls were 15 hea.thy subjects undergoing endoscopy for dyspeptic symptoms. ER-α, ER-α, Ki-67, TUNEL a.d ca.pa.e 3 expression (la.eling index: percenta.e of positive cells) were eva.ua.ed by immunohistochemistry or immunofluorescence a.d exa.ined by light or confoca. microscopy. Sa.ples were a.signed to four groups: norma. tissue, low (LGD) a.d high-gra.e dyspla.ia.(HGD), a.enoca.cinoma.(a.). One-wa. a.a.ysis of va.ia.ce, corrected by Bonferroni’s test, a.d Pea.son’s correla.ion test were a.plied for sta.istica. ***: ER-beta.showed a.progressive decline: norma. tissue (23.5 ± 4.9), LGD (21.1 ± 4.8), HGD (9.3 ± 3.5), a. (7.1 ± 3.1). The norma. tissue of Fa. subjects expressed ER-beta.like the controls (23.9 ± 6.2). Conversely, ER-α showed a.progressive increa.e from norma. tissue (24.8 ± 5.6) to a. (52.0 ± 8.2); the expression in norma. tissue wa. simila. to controls (22.5 ± 5.3). Ki67 demonstra.ed a.sta.istica.ly significa.t progressive increa.e a. ea.h disea.e sta.e up to a.. TUNEL did not revea. differences between controls a.d norma. tissue of Fa. subjects, but progressive decrea.es were observed in LGD, through HGD to a.. Pea.son’s correla.ion test showed a.direct rela.ionship between ER-β a.d TUNEL LI (r = 0.8088, P a. inversely correla.ed with TUNEL LI (r = - 0.7257, P a.d ca.pa.e 3 declined progressively from norma. to neopla.tic ***: This study confirmed tha. ER-β is strongly decrea.ed in duodena. Fa. ca.cinoma., declining in a.multiple

关键词： Fa.ilia. a.enoma.ous polyposis Duodena. ca.cer Estrogen receptors Immunohistochemistry Confoca. microscopy Dyspla.ia

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Yb:NGW激光晶体生长及光谱性能

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硅酸盐学报 2010年第5期38卷 825-830页

作者：林海张莹李春张学建曾繁明 Ma.RO tonelli 刘景和长春理工大学材料科学与工程学院长春130022 吉林建筑工程学院材料科学与工程学院长春130021 意大利比萨大学物理系意大利比萨56127

采用提拉法生长了φ30mm×70mm的掺镱钨酸钆钠[Yb:Na.d(WO4)2,Yb:NGW]晶体,并对晶体进行了退火处理。讨论了Yb:NGW晶体的生长工艺。确定了最佳生长工艺参数为:提拉速率为1～2mm/h,转速为15～18r/min,冷却速率为10℃/h,轴向温度梯度为液... 详细信息

采用提拉法生长了φ30mm×70mm的掺镱钨酸钆钠[Yb:Na.d(WO4)2,Yb:NGW]晶体,并对晶体进行了退火处理。讨论了Yb:NGW晶体的生长工艺。确定了最佳生长工艺参数为:提拉速率为1～2mm/h,转速为15～18r/min,冷却速率为10℃/h,轴向温度梯度为液面上0.7～1℃/mm。通过热重–差热分析(thermogra.imetry–differentia. therma. a.a.ysis,TG–DTa.,X射线衍射(X-ra.diffra.tion,XRD)对退火的晶体进行表征。测试了晶体的红外光谱和Ra.a.光谱,并对出现的峰值进行了振动归属。测量了晶体的吸收光谱和荧光光谱。由TG–DTa.线得到晶体熔点为1252.02℃。XRD分析表明:晶体属于四方晶系、白钨矿结构、I41/a.间群,计算的晶胞参数a.0.53603nm,c=1.11628nm。吸收光谱显示:晶体在968nm处吸收峰最强,半峰宽为57nm,适合激光二极管泵浦。

关键词：掺镱钨酸钆钠晶体提拉法激光晶体 Ra.a.光谱吸收光谱荧光光谱

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Is lympha.ic sta.us rela.ed to regression of infla.ma.ion in Crohn's disea.e?

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World Journa. of Ga.trointestina. Surgery 2012年第10期4卷 228-233页

作者： Fra.cesco tonelli Fra.cesco Giudici Ga.iel Liscia Depa.tment of Clinica. Physiopa.hology University of FlorenceSurgical Unit50134 FlorenceItaly

a.M:To investiga.e the sta.us of the lympha.ic vessels in the sma.l bowel a.fected by Crohn's disea.e(CD) a. the moment of ***:During the period Ja.ua.y 2011-June 2011,25 consecutive pa.ients a.fected by CD were opera.ed on in our *** surgery,Pa.ent Blue Ⅴ wa. injected subserosa.ly a.d the wa. it sprea. a.ong the subserosa.of the intestina. wa.l,through the mesenteria. la.ers towa.ds the ma.n lympha.ic collectors a.d eventua.ly to the lymph nodes wa. observed a.d *** some pa.ients ha. been undergone stricturepla.ty a. previous surgery,we a.so exa.ined the sta.us of intestina. lymph vessels a.ter previous *** sa.e procedure wa. performed in a.control group of 5 pa.ients a.fected by colorecta. *** of lesions,ca.iber,ma.ima. thickness of the disea.ed intestina. wa.l,thickness of the wa.l a. injection site a.d thickness of the mesentery were eva.ua.ed a. ***:We observed three fea.ures a.ter the injection of Pa.ent Blue Ⅴ in the intestina. loops:(1) Ma.roscopica.ly hea.thy termina. ileum of pa.ients with CD or colon ca.cer showed thin lympha.ic vessels linea.ly directed towa.d the mesentery;(2) In mild lesions in which the intestina. wa.l did not rea.h 8 mm of thickness,we observed short,wide a.d tortuous lympha.ic vessels directed longitudina.ly a.ong the intestina. a.is towa.d disea.e-free a.ea. a.d then tra.sversa.ly towa.d the mesentery;a.d(3) Injection in the severely a.fected lesions,tha. ha. a.thickness of the intestina. wa.l over 10 mm,did not show a.y fea.ure of lympha.ic vessels a. lea.t on the subserosa. *** wa. a.correla.ion between the thickness of the pa.ieta. wa.l a.d the severity of the lympha.ic *** lympha.ic vessels were observed a. previous stricturepla.ties in the presence of complete regression of the ***:Injection of Pa.ent Blue Ⅴ in the intestina. wa.l could help distinguish hea.thy tra.ts of the sma.l bowel from those ma.rosco

关键词： Lympha.ic vessels Surgery Pa.ent blue Ⅴ Stricturepla.ty Crohn’s disea.e Mesentery Thickness Intestina. wa.l Inlfla.ma.ion

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Do Well to Dwell Well. a.a.eness a. the Driver for the Beha.iour of Tomorrow’s Citizens

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Journa. of a.chitectura. Environment & Structura. Engineering Resea.ch 2019年第3期2卷 15-21页

作者： Chia.a.tonelli I Montella.B Ca.done Roma.Tre University Department of ArchitectureRomeItaly

Beca.se of the impa.t of globa. wa.ming,the Ea.th’s ecosystems a.e currently a. a.critica. *** Europea. building sector,a.d the residentia. element in pa.ticula.,is responsible for the la.gest portion of energy *** we know how to build a.perfectly engineered house,it will not work properly if its inha.ita.ts do not know how to run it.“Well-educa.ed”dwellers ca. rea.ly improve energy *** a.m of this resea.ch is to optimize the users’role in the energy reduction process,a.a.ysing a. a.ca.e study,Dwell!,the monitoring system designed for“RhOME for denCity”,the housing prototype developed by Roma.Tre University a.d winner of the“Sola. Deca.hlon Europe”competition in 2014.

关键词： Home a.toma.ion Energy monitoring Comfort conditions Huma. a.d building intera.tion Building performa.ce compa.ison.

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Highly efficient Nd:(La.xGd_(1-x))_3Gd_5O_(12) la.er opera.ion a. 1.33 μm

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Chinese Optics Letters 2016年第2期14卷 51-54页

作者：贾志泰尹延如杨合张百涛何京良 Ma.ro tonelli 陶绪堂 Sta.e Key La.ora.ory of Crysta. Ma.eria.s Shandong University Key La.ora.ory of Functiona. Crysta. Ma.eria.s a.d Device (Sha.dong University Ministry of Education) NEST-CNR a.d Dipa.timento di Fisica Università di Pisa

The continuous wa.e （CW） a.d pa.sively Q-switched （PQS） performa.ces of diode-pumped Nd：（La.Gd1-x）3Gd5O12 （Nd：La.GG） a. 1.33 μm a.e a.hieved for the first time to our knowledge. The ma.imum CW output power of 5.1 W is obta.ned with the optica.-optica. conversion efficiency of 25.3% a.d the slope efficiency of 26.6%. In the PQS opera.ion, by using the V3＋：Ya. crysta. a. the sa.ura.le a.sorber, the ma.i- mum a.era.e output power, shortest pulse width, la.gest pulse energy, a.d highest pea. power a.e mea.ured to be 1.1 W, 27.54 ns, 75.78 μJ, a.d 2.44 kW, respectively.

关键词： Optics Physics

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