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Hepatocellular carcinoma recurrence in HCV patients treated with direct-acting antivirals after curative treatment

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Hepatoma Research 2019年第5期5卷 26-36页

作者： Shinichiro Nakamura Kazuhiro Nouso Hiroyuki okada Hideki Onishi Shin-ichi Fujioka YasuyukiAraki Shouta Iwadou Takashi Kumada Hidenori Toyoda Kenta Motomura Kazuya Kariyama Haruhiko Kobashi Toshihiko Kaneyoshi Masaharu Ando Akio Moriya Hideaki Taniguchi YouichiMorimoto Hiroaki Hagihara Masatoshi Tanaka Okayama University Graduate School of Medicine Dentistry and Pharmaceutical SciencesOkayama 700-8558Japan Okayama Saiseikai General Hospital Okayama 700-8558Japan Hiroshima City Hiroshima Citizens Hospital Hiroshima 731-0293Japan Ogaki Municipal Hospital Gifu 503-8502Japan Iizuka Hospital Fukuoka 820-8505Japan Okayama City Hospital Okayama 700-8557Japan Okayama Red Cross General Hospital Okayama 700-8607Japan Fukuyama Medical Center Hiroshima 720-8520Japan Mitoyo General Hospital Kagawa 769-1695Japan Tottori Municipal Hospital Tottori 680-8501Japan Kurashiki Central Hospital Okayama 710-8602Japan Sumitomo Besshi Hospital Ehime 792-8543Japan Yokokura Hospital Fukuoka 839-0215Japan Japanese Red Cross Society Himeji Hospital Hyogo 670-8540Japan

Aim:The increased risk of hepatocellular carcinoma(HCC)recurrence in hepatitis C virus(HCV)-infected patients treated with direct-acting antivirals(DAAs)after curative treatment for HCC is *** purpose of this study was to examine the risk of HCC recurrence after DAA ***:We conducted a retrospective cohort study of 312 consecutive patients with HCV-related HCC who received DAA therapy in participating institutions between September 2014 and July *** patients received curative ;hepatectomy or radio-frequency *** calculated the annual incidence of HCC recurrence after DAA therapy and identified the risk factors for HCC recurrence using Cox regression ***:The median age was 74 years old,and a sustained virological response was achieved by 288 *** 3-year-overall survival rate was 95.4%in a median follow-up period of 855 *** recurred in 135 *** 1-,2-and 3-year recurrence rates were 18.3%,38.8%and 55.4%,respectively.A multivariate analysis revealed that the following factors were associated with HCC recurrence:multiple tumors at the first HCC treatment[hazard ratio(HR)=2.21;95%CI:1.41-3.49],a history of multiple treatments for HCC(HR=1.97;95%CI:1.28-3.02),andα-fetoprotein(AFP-L3)≥10%at the initiation of DAA therapy(HR=4.74;95%CI:2.10-10.7).Conclusion:Among patients treated with DAAs after the curative treatment of HCC,multiple tumors at the first HCC treatment,multiple prior HCC treatments and a high AFP-L3 level before DAA therapy were associated with recurrence,and the rate of recurrence was comparable to that before the DAA era.

关键词： Hepatocellular carcinoma hepatitis C virus direct-acting antiviral recurrence

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关于水力机械磨蚀的研究

陕西水力发电 1993年第1期9卷 13-17页

作者：袁清阁岩井善郎陕西机械学院福井大学福井大学 710048 日本910 日本910

用磁致伸缩振动仪与含砂射流设备所构成的新型试验装置对空蚀、磨蚀单独作用或联合作用下几种金属材料的表面损伤状况和失重量等进行了研究.研究发现,联合作用时失重量也随时间而增长,但没有通常情况下的潜伏期,且不是各自单独作用时失... 详细信息

用磁致伸缩振动仪与含砂射流设备所构成的新型试验装置对空蚀、磨蚀单独作用或联合作用下几种金属材料的表面损伤状况和失重量等进行了研究.研究发现,联合作用时失重量也随时间而增长,但没有通常情况下的潜伏期,且不是各自单独作用时失重量的叠加.还发现泥沙的存在,对空蚀可起到某种抑制作用.

关键词：水力机械空蚀磨蚀试验

Correction to:Proposed nomenclature for Pseudallescheria,Scedosporium and related genera

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Fungal Diversity 2022年第2期113卷 193-194页

作者： Michaela Lackner G.Sybren de Hoog Liyue Yang Leandro Ferreira Moreno Sarah A.Ahmed Fritz Andreas Josef Kaltseis Markus Nagl Cornelia Lass-Florl Brigitte Risslegger Gunter Rambach Cornelia Speth Vincent Robert Walter Buzina Sharon Chen Jean-Philippe Bouchara Jose F.Cano-Lira Josep Guarro Josepa Gene Fabiola Fernandez Silva Rosa Haido Gerhard Haase Vladimir Havlicek Dea Garcia-Hermoso Jacques F.Meis Ferry Hagen Martin Kirchmair Johannes Rainer Katharina Schwabenbauer Mirjam Zoderer Wieland Meyer Felix Gilgado Vania A.Vicente Elena Pieckova Monika Regenermel Peter-Michael Rath Joerg Steinmann Xisto Wellington de Alencar Françoise Symoens Kathrin Tintelnot Krzysztof Ulfig Aristea Velegraki Anna Maria Tortorano Sandrine Giraud Sara Mina Kinga Rigler-Hohenwarter Fernando L.Hernando Andoni Ramirez-Garcia Aize Pellon Jashanpreet Kaur Eliana Barreto Bergter Jardel Vieira de Meirelles Ingrid Dutra da Silva Laurence Delhaes Ana Alastruey-Izquierdo Ruo-yu Li Qiaoyun Lu Tarek Moussa Omar Almaghrabi Hassan Al-Zahrani Gen okada Shuwen Deng Wangqing Liao Jingsi Zeng Jouni Issakainen Livia Cristina Liporagi Lopes Division of Hygiene and Medical Microbiology Innsbruck Medical UniversityInnsbruckAustria CBS Fungal Biodiversity Centre UtrechtThe Netherlands Institute for Biodiversity and Ecosystem Dynamics University of AmsterdamAmsterdamThe Netherlands Sun Yat-Sen Memorial Hospital Sun Yat-Sen UniversityGuangzhouChina Medical University of Graz GrazAustria Centre for Infectious Diseases and Microbiology Westmead HospitalWestmeadAustralia Laboratoire de Parasitologie-Mycologie Centre Hospitalier UniversitaireAngersFrance Unitats de Microbiologia i d’Anatomia Patologica Facultat de Medicina i Ciencies de la Salut IISPVUniversitat Rovira i VirgiliReusSpain Universidade Federal do Estado do Rio de Janeiro Rio de JaneiroBrazil Institute of Medical Microbiology University Hospital RWTHAachenGermany Institute of Microbiology Academy of SciencesPragueCzech Republic Institut Pasteur Unite de Mycologie MoleculaireCentre National de Reference Mycoses Invasives et AntifongiquesParisFrance Department of Medical Microbiology and Infectious Diseases Canisius-Wilhelmina HospitalNijmegenThe Netherlands Department of Medical Microbiology RadboudumcNijmegenThe Netherlands Institute of Microbiology eopold-Franzens-University InnsbruckInnsbruckAustria Molecular Mycology Research Laboratory Centre for Infectious Diseases and MicrobiologySydneyMedical School—Westmead HospitalMarie Bashir Institute for Infectious Diseases and BiosecurityThe University of SydneyWestmead Millennium InstituteWestmeadNSWAustralia Basic Pathology Department Federal University of Parana StateCuritibaParanaBrazil Fellowship from Conselho Nacional de Desenvolvimento Cientifico e Tecnologico(CNPq) BrasiliaBrazil Institute of Preventive and Clinical Medicine BratislavaSlovakia Institut für Hygiene und Mikrobiologie Landesklinikum St.Pölten St.PoltenAustria Institute of Medical Microbiology University Hospital EssenEssenGermany Nursing School of Unigranrio Rio de JaneiroBrazil Scientific Institute of Public Health Culture Collect

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本刊国际编委的信

中华临床营养杂志 1993年第1期11卷 10-13页

作者： Dougles W. Wilmore M.D. 杨少卫 Erik Vinnars M.D Ph.D. Akira okada M.D. F.A.C.S. 美国哈佛医学院Brgham and Women’s Hospital 瑞典Karolinska大学St. Goran医院加强医疗单位和麻醉科日本Osaka University医学院儿外科

My warmest congratulations to the Chinese physicians and their associates who are interested in the nutritional and metabolic care of hospitalized patients for their founding of a new journal dealing with the science ... 详细信息

关键词： enteral nutrition 国际编委肠内营养支持 dealing founding nutrients 支持治疗脂肪乳剂病人营养状况

ALC-CH系统在水热处理过程中的物理化学变化 Ⅰ 水热处理温度的影响

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硅酸盐学报 1999年第4期27卷 385-391页

作者：潘志华杨南如增田嗣也高田みのり冈田能彦齐藤亨南京化工大学日本太平洋水泥(株)佐仓研究所

采用ＴＧ－ＤＴＡ，ＩＲ，ＸＲＤ和ＮＭＲ对ＡＬＣ（压蒸轻质混凝土）废渣中添加氢氧化钙后的ＡＬＣ－ＣＨ系统，在水热处理过程中的物理化学变化进行了分析，同时用ＢＥＴ方法测定了不同温度水热处理物的比表面积．结果表明，ＡＬＣ渣... 详细信息

采用ＴＧ－ＤＴＡ，ＩＲ，ＸＲＤ和ＮＭＲ对ＡＬＣ（压蒸轻质混凝土）废渣中添加氢氧化钙后的ＡＬＣ－ＣＨ系统，在水热处理过程中的物理化学变化进行了分析，同时用ＢＥＴ方法测定了不同温度水热处理物的比表面积．结果表明，ＡＬＣ渣添加适量氢氧化钙，经１４０～２００℃下水热处理３ｈ的水热处理物中形成了新的水化硅酸钙α－Ｃ２ＳＨ．α－Ｃ２ＳＨ的形成量随水热处理温度的提高而增加．水热处理物的比表面积波动于１２～２２ｍ２／ｇ之间．提高水热处理温度，处理物的比表面积首先随之增大，但超过１６０℃时处理物的比表面积会重新减小．所以，提高水热处理温度将有利于以合成主要含β－Ｃ２Ｓ的贝利特水泥或活性混合材为目的的后续煅烧过程．同时，为了保证水热处理物具有较高的比表面积。

关键词：压蒸轻质混凝土废渣水热处理 ALC-CH系统

慢性血栓栓塞性肺动脉高压病人的诊断线索和治疗途径

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中华结核和呼吸杂志 1997年第Z1期 109页

作者： okada O Tanabe N Katoh K Yasuda J Yamamoto T Hayashi A Mori N Sugimoto N Kasahara Y Kuriyama T 刘震宇(译) ChibaUniversitySchoolofMedicine Chiba Japan DepartmentofChestMedicine ChibaUniversitySchoolofMedicine Chiba Japan DepartmentofChestMedicine ChibaUniversitySchoolofMedicine Chiba DepartmentofChestMedicine Japan DepartmentofChestMedicine ChibaUniversitySchoolofMedicine Chiba Japan DepartmentofChestMedicine ChibaUniversitySchoolofMedicine Chiba Japan DepartmentofChestMedicine ChibaUniversitySchoolofMedicine ChibaUniversitySchoolofMedicine Chiba Japan DepartmentofChestMedicine ChibaUniversitySchoolofMedicine Chiba Japan DepartmentofChestMedicine ChibaUniversitySchoolofMedicine Chiba Chiba Japan Japan DepartmentofChestMedicine ChibaUniversitySchoolofMedicine Chiba Japan DepartmentofChestMedicine

Dilation of a severe bilioenteric or pancreatoenteric anastomotic stricture using a Soehendra Stent Retriever

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World Journal of Gastrointestinal Endoscopy 2013年第8期5卷 412-416页

作者： Koichiro Tsutsumi Hironari Kato Ichiro Sakakihara Naoki Yamamoto Yasuhiro Noma Shigeru Horiguchi Ryo Harada Hiroyuki okada Kazuhide Yamamoto Department of Gastroenterology and Hepatology Okayama University Graduate School of Medicine Dentistry and Pharmaceutical Sciences Department of Endoscopy Okayama University Hospital

Bilioenteric or pancreatoenteric anastomotic stric-tures often occur after surgery for a pancreaticobiliary disorder. Therapeutic endoscopic retrograde cholan-giopancreatography using balloon enteroscopy has been shown to be feasible and effective in patients with such strictures. However, when a benign anas-tomotic stricture is severe, a dilation catheter cannot pass through the stricture despite successful insertion of the guidewire. We report on the usefulness of the Soehendra Stent Retriever over a guidewire for dilating a severe bilioenteric or pancreatoenteric anastomotic stricture under short double-balloon enteroscopy, in two patients with surgically altered anatomies.

关键词： Bilioenteric anastomotic stricture Soehen-dra Stent Retriever Dilation Pancreatoenteric anasto-motic stricture Double-balloon enteroscopy

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射精后前列腺周围带和精囊T2值的显著改变

国际医学放射学杂志 2018年第3期 362-362页

作者： T.Shin Y.Kaji T.Shukuya M.Nozaki S.Soh H.okada 刘磊 Department of Radiology Dokkyo Medical University

摘要目的应用MRI分析射精后前列腺和精囊(SV)的定量改变。方法招募10名健康的年轻男性受试者,并在2次连续的射精前后进行T2WI和Tmapping MRI检查。分别

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温度与赤霉素对紫罗兰生育及其开花的影响

广州大学学报（自然科学版） 2004年第1期3卷 27-30页

作者：黄家总颜艳冈田芳明傅家瑞广东农垦科技中心广东广州510507 广州云港园林绿化公司广东广州510405 奈良县田原本高等农业学校中山大学生命科学院广东广州510275

利用自然光人工气候室,设置3个不同温度(低温区昼20℃/夜15℃,中温区昼25℃/夜20℃,高温区昼30℃/夜25℃)对紫罗兰中晚熟品种'彼岸王'栽培试验;并使用植物生长调节剂赤霉素(GA)(浓度25×10-5)进行3、4、5次喷雾处理.结果显示,低温区GA... 详细信息

利用自然光人工气候室,设置3个不同温度(低温区昼20℃/夜15℃,中温区昼25℃/夜20℃,高温区昼30℃/夜25℃)对紫罗兰中晚熟品种'彼岸王'栽培试验;并使用植物生长调节剂赤霉素(GA)(浓度25×10-5)进行3、4、5次喷雾处理.结果显示,低温区GA喷雾处理开花率达100%,对照没有开花.中温区与高温区对照与各处理均未见开花.3个温度区赤霉素GA喷雾处理分别比对照区株高,节数少.

关键词：温度赤霉素生育开花紫罗兰