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Predictor Analysis of Mid-Term Left Atrial Reverse Remodeling after Mitral Valve Surgery

World Journal of Cardiovascular Surgery 2013年第2期3卷 52-57页

作者： Kaoru Matsuura Kenji Mogi Manabu Sakurai tomonori kawamura Yoshiharu Takahara Funabashi Municipal Medical Center Department of Cardiovascular Surgery Chiba Japan

Objective: The aim of this study was to predict mid-term left atrial reverse remodeling after mitral valve surgery. Patients and Methods: Echocardiographic data was obtained preoperatively and at follow-up from 105 patients who underwent mitral valve surgery. Left atrial volume (LAV) was decreased by >30% from baseline in 43 patients (group A), but not in 62 patients (group B). Results: Patients in group A were younger (p = 0.0029). Male was more (p = 0.05) and prosthesis size was bigger in group A (p = 0.005). Only age was a predictor of left atrial reverse remodeling in a logistic regression model (OR = 0.93, 95% CI 0.88 - 0.99;p = 0.03). Late mean trans-mitral pressure gradient was lower in group A than in group B (p = 0.01). There was a weak correlation between the change in left ventricular end-diastolic diameter (LVDd) and LAV (correlation coefficient 0.27, 95% CI 0.07 - 0.45;p = 0.008). Survival and freedom from major adverse cardiac events did not differ between the groups (p = 0.31 and p = 0.87 by log-rank test). Conclusions: Age was the only predictor of left atrial reverse remodeling. There was a weak correlation between changes in LVDd and LAV.

关键词： Atrium Mitral Valve Outcomes

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Non-steroidal anti-inflammatory drug-induced small bowel injuries identified by double-balloon endoscopy

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World Journal of Gastroenterology 2005年第31期11卷 4861-4864页

作者： Yoshikazu Hayashi Hironori Yamamoto Hiroto Kita Keijiro Sunada Hiroyuki Sato tomonori Yano Michiko Iwamoto Yutaka Sekine Tomohiko Miyata Akiko Kuno Takaaki Iwaki Yoshiyuki kawamura Hironari Ajibe Kenichi Ido Kentaro Sugano Department of Internal Medicine

AIM: To clarify clinical features of the NSAID-induced small bowel lesions using a new method of ***: This is a retrospective study and we analyzed seven patients with small bowel lesions while taking NSAIDs among 61 patients who had undergone doubleballoon endoscopy because of gastro-intestinal bleeding or anemia between September 2000 and March 2004, at Jichi Medical School Hospital in Japan. Neither conventional EGD nor colonoscopy revealed any lesions of potential bleeding sources including ulcerations. Double-balloon endoscopy was carried out from oral approach in three patients, from anal approach in three patients, and from both approaches in one ***: Ulcers or erosions were observed in the ileum in six patients and in the jejunum in one patient, *** ulcers were multiple in all the patients with different features from tiny punched out ulcers to deep ulcerations with oozing hemorrhage or scar. All the patients recovered uneventfully and had full resolution of symptoms after suspension of the ***: NSAIDs can induce injuries in the small bowel even in patients without any lesions in both the stomach and colon.

关键词：抗炎症药小肠损伤双球内窥镜检查方法

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定量质子磁共振波谱对鉴别良性与恶性脑膜瘤的价值

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生物医学工程学杂志 2011年第6期28卷 1103-1109页

作者：月强磯辺智範柴田靖川村拓阿武泉松村明四川大学华西医院放射科中国成都610041 筑波大学大学院人間総合科学研究科脑神经外科日本筑波305-8575 筑波大学大学院人間総合科学研究科放射線科日本筑波305-8575

本研究致力于探讨定量质子磁共振波谱(MRS)对鉴别良性与恶性脑膜瘤的价值。研究利用1.5T磁共振仪,对23例脑膜瘤(良性组(WHO I级)19例,恶性组(WHOⅡ～Ⅲ级)4例)进行单体素MRS检查(PRESS序列,TR/TE=2000ms/68,136,272ms),通过指数衰减模... 详细信息

本研究致力于探讨定量质子磁共振波谱(MRS)对鉴别良性与恶性脑膜瘤的价值。研究利用1.5T磁共振仪,对23例脑膜瘤(良性组(WHO I级)19例,恶性组(WHOⅡ～Ⅲ级)4例)进行单体素MRS检查(PRESS序列,TR/TE=2000ms/68,136,272ms),通过指数衰减模型估计组织水和胆碱(Choline,Cho)的T2弛豫时间,并以组织水为内参照计算Cho的绝对浓度,然后按MRS体素内坏死或囊变组织的比例对Cho浓度进行校正。研究发现,良、恶性脑膜瘤的组织水T2弛豫时间分别是(105±41)ms和(151±42)ms,差异有显著性(P=0.033)。良、恶性脑膜瘤的Cho T2弛豫时间分别是(242±73)ms和(316±102)ms,无显著差异(P=0.105)。良、恶性脑膜瘤的Cho浓度在校正前分别是(2.86±0.86)mmol/kg wet weight和(3.53±0.60)mmol/kg wet weight,在校正后分别是(2.98±0.93)mmol/kg wet weight和(4.58±1.22)mmol/kg wet weight,校正后差异具有显著性(P=0.019)。研究表明,用定量质子磁共振波谱测定组织水T2弛豫时间和Cho绝对浓度,对鉴别良性和恶性脑膜瘤具有重要的参考价值。

关键词：脑膜瘤磁共振波谱 T2弛豫时间代谢物浓度

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