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Number and distribution of eosinophils and lymphocytes in the Japanese pediatric gastrointestinal tract:in search of a definition for"abnormally increased eosinophils"

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World Journal of Pediatrics 2023年第3期19卷 251-260页

作者： Mai Iwaya Shota Kobayashi Yoshiko Nakayama Sawako Kato Shingo Kurasawa tomomitsu sado Yugo lwaya Takeshi Uehara Hiroyoshi Ota Department of Laboratory Medicine Shinshu University Hospital3-1-1 AsahiMatsumotoNaganoJapan Department of Pediatrics Shinshu University School of MedicineMatsumotoJapan Division of Gastroenterology and Hepatology Department of MedicineShinshu University School of MedicineMatsumotoJapan Department of Laboratory Medicine Shinshu University School of MedicineMatsumotoJapan Department of Clinical Laboratory Sciences School of Health SciencesShinshu UniversityMatsumotoJapan

Background Primary eosinophilic gastrointestinal disorders(EGIDs)constitute chronic allergic *** number of eosinophils is one of the diagnostic criteria;more than 20 eosinophils per high-power field(HPF)in the gastrointestinal(GI)tract are considered abnormal in ***,the quantity of eosinophils considered normal varies according to anatomical location and geographical region;such values have not been reported in Japanese pediatric patients,nor have the numbers of lymphocytes in the normal pediatric *** establish a reference for defining diagnostic criteria for EGIDs,we evaluated the number of eosinophils in the normal Japanese pediatric GI *** We examined 131 biopsy cases without significant clinical history,endoscopic abnormality,or histological *** analysis of CD3 and CD20 was *** The mean eosinophil density was highest in the cecum(49.5±22.4 per HPF).Counts of more than 20 eosinophils per HPF were observed in the duodenum[bulb(20.0±9.6)and second portion(30.0±15.8)],terminal ileum(38.3±22.7),cecum(49.5±22.4),ascending colon(42.3±25.3),transverse colon(29.4±17.0),and descending colon(32.2±17.9).Counts of fewer than 10 eosinophils per HPF were observed in the stomach and rectum;a count of fewer than one eosinophil per HPF was observed in the *** than 100 CD3-positive T cells per HPF were observed in the *** The mean numbers of eosinophils in the bowel were greater than 20 per *** Japanese pediatrics,the cur-rent threshold eosinophil count should be revised.

关键词： Eosinophil Gastrointestinal tract Japanese Lymphocyte Normal Pediatrics

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Gamma-Ray Bursts Generated by Hyper-Accreting Kerr Black Hole

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International Journal of Astronomy and Astrophysics 2019年第3期9卷 247-264页

作者： Feyiso sado Department of Physics Addis Ababa University Addis Ababa Ethiopia

The observed properties of Gamma-Ray Bursts such as rapid variability of X-ray light curve and large energies strongly signature the compact binary, disk accreting system. Our work particularly highlights the extremely rotating, disk accreting black holes as physical source of the flares variability and X-ray afterglow plateaus of GRBs. We investigate the compact binary mergers (neutron star - neutron star and neutron star onto black hole) and gravitational core collapse of super massive star, where in both cases hyper-accreting Kerr hole is formed. The core collapse in a powerful gravitational wave explained as a potential source for the radiated flux of hard X-rays spectrum. We described the evolution of rapidly rotating, accreting BH in general relativity and the relativistic accretion flow in resistive MHD for viscous radiation. We compute the structure of accretion disk, the accretion luminosity of the dynamical evolution of inner accretion disk and precisely determine their radiation spectra, and compare to observational data of X-ray satellites. Finally, we obtained the resulting disk radiation basically explained as the X-ray luminosity of the central source, such as LMC X-1 and GRO J1655-40. These results are interestingly consistent with observational data of galactic X-ray source binary systems such as X-ray luminosities of Cygnus X-1 and Seyfert galaxies (NGC 3783, NGC 4151, NGC 4486 (Messier 87)) which are powerful emitters in X-ray and gamma-ray wavebands of the observed X-ray variability with typical luminosity.

关键词： Relativistic Disk Accreting BH-Gamma Rays Bursts-Radiation X-Ray Luminosity

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Pseudoelastic effect in autoparametric non-ideal vibrating system with SMA spring

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Theoretical & Applied Mechanics Letters 2012年第4期2卷 69-74页

作者： Danuta sado Marek Pietrzakowski Krzysztof Gajos Warsaw University of Technology 84 Narbutta Str.02-524 WarsawPoland PEC Legionowo 37 Sowinski Str.05-120 LegionowoPoland

In this paper a three degrees of freedom autoparametric system with limited power supply is investigated numerically. The system consists of the body, which is hung on a spring and a damper, and two pendulums connected by shape memory alloy （SMA） spring. Shape memory alloys have ability to change their material properties with temperature. A polynomial constitutive model is assumed to describe the behavior of the SMA spring. The non-ideal source of power adds one degree of freedom, so the system has four degrees of freedom. The equations of motion have been solved numerically and pseudoelastic effects associated with the martensitic phase transformation are studied. It is shown that in this type system one mode of vibrations might excite or damp another mode, and that except different kinds of periodic vibrations there may also appear chaotic vibrations. For the identification of the responses of the system＇s various techniques, including chaos techniques such as bifurcation diagrams and time histories, power spectral densities, Poincare maps and exponents of Lyapunov may be used.

关键词： autoparametric vibrations non-ideal system shape memory alloy chaos

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VISUALIZATION OF DYNAMIC ORGANIZATION OF CYTOSKELETON GELS IN LIVING CELLS BY HYBRID-SPM

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Chinese Journal of Polymer Science 2003年第2期21卷 169-174页

作者： K.Kawabata Y.sado M.Nagayama T.Nitta K.Nemoto Y.Koyama H.Haga Divisions of Biological Sciences Graduate School of Science Hokkaido University 060-0810 SapporoDivisions of Physics Graduate School of Science. Hokkaido University 060-0810 SapporoDivisions of Physics Graduate School of Science. Hokkaido University 060-0810 SapporoDivisions of Physics Graduate School of Science. Hokkaido University 060-0810 SapporoDivisions of Physics Graduate School of Science. Hokkaido University 060-0810 SapporoDepartment of Biochemistry Hokkaido University Graduate School of Medicine Sapporo 060-8638 JapanDivisions of Physics Graduate School of Science Hokkaido University 060-0810 Sapporo

We succeeded in performing of hybrid Scanning Probe Microscopy (hybrid-SPM) in which mechanical-SPM andfluorescence microscopy are combined. This technique is able to measure simultaneously mechanical properties anddistribution of cytoskeletons of living cells by using green fluorescent protein. We measured evolution of both local elasticityand distributions of actin stress fibers in an identical fibroblast living in physiological conditions. The SPM experimentsrevealed that stiffer lines develop in living cells, which correspond to actin stress fibers. The elasticity of the actin stressfibers is as high as 100 kPa. We discuss mechanical effects on the development of actin filament networks.

关键词： Scanning probe microscopy Green fluorescent protein Fibroblast Cell migration, Cytoskeleton Elasticity

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长期地震预报算法

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世界地震译丛 1989年第3期20卷 5-32,4页

作者： sado.,MA 卢振业

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Superior sinus venosus atrial septal defect

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Journal of Geriatric Cardiology 2018年第10期15卷 649-652页

作者： Konstantinos C Theodoropoulos Alexandros Papachristidis Giovanni Masoero Michael Papitsas Valentina Cospite Fulya Avci Demir Daniel M.sado Mark J.Monaghan Department of Cardiology King 's College HospitalKing's College LondonLondonUK Department of Cardiology St Thomas'HospitalLondonUK

Atrial septal defect (ASD)is the third commonest congenital heart disease in *** most common type of ASD is the ostium secundum accounting for 75%-80%of all *** common are the ostium primum (accounting for 15%of all A... 详细信息

关键词： Atrial septal defect Cardiovascular magnetic resonance Sinus venosus defect Transesophageal echocardiography

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Rationale of a Cross-Sectional Descriptive Study on Associated Factors and Prognosis Maternal-Fetal Links to Early Onset Preeclampsia at the University Clinics of Kinshasa, DR Congo

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Open Journal of Obstetrics and Gynecology 2023年第11期13卷 1869-1880页

作者： Muela Andy Mbangama Mbuwe Yves Bozeme Mushengezi Dieudonné Sengeyi Mbenza Benjamin Longo Vangu Roland Vangu sado Jacques Mokassa Mbaya Eloge Ilunga Sendeke Patrick Mogwo Yangbo Sonia Sabanga Feruzi Michel Mangala Kebela Thésée Kogomba Malu Merveille Kinanga Departement of Gynecology and Obstetrics Univeristy Clinics of Kinshasa Kinshasa The Democratic Republic of Congo Departement of Internal Medicine Univeristy Clinics of Kinshasa Kinshasa The Democratic Republic of Congo Departement of Gynecology and Obstetrics Univeristy of President Joseph KASA-VUBU Boma The Democratic Republic of Congo Pharmaceutical Sciences Faculty University of Kinshasa Kinshasa The Democratic Republic of Congo

Background: Preeclampsia (PE) is one of the forms of hypertensive diseases that occur during pregnancy. Early-onset preeclampsia (EOP), which occurred before 34 weeks, proved to be the deadliest. Indeed, it is characterized by a poor maternal and fetal prognosis. EOP has a disparate incidence in the world varying between 0.9% and 31%. Several risks factors are associated with the occurrence of EOP, which is responsible of several adverse obstetrical outcomes. Complications can affect up to 85% of pregnant women with EOP, especially when EOP appears very early, before 28 or even 25 weeks’ gestation. Objectives: To determine frequency of EOP at the University Clinics of Kinshasa, to describe sociodemographic and clinical characteristics of pregnant women with EOP and to identify its risks factors and its association adverse obstetrical outcomes. Methods: The study will be a cross-sectional analytical study in University Clinics of Kinshasa from January 2016 to December 2022. The minimal size will be 119. Our study population will consist of pregnant women who consult for antenatal best care and are neonates in our Clinic. Result will be presented as percentage proportion. Comparison and proportion means between groups will be made using Student’s test and Pearson’s chi-square test, respectively. Our test will be statistically significant for a p-value ≤ than less 0.05. Data will be collected and analysed anonymously and confidentiality. Conclusion: We believe that our study should enable us to identify profile of gestational carriers at risk of EOP in our environment, as well as prognosis associated with this entity, with a view to arousing particular interest in EOP.

关键词： Early-Onset Preeclampsia Associated Factors Prognosis University Clinics of Kinshasa

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