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Neural Regeneration Research 2018年第7期13卷 1193-1194页

作者： tomoko Hirokawa Kohtaro Takei Molecular Medical Bioscience Laboratory Yokohama City University Graduate School of Medical Life Science

It is well known that primates,including humans,hardly recover motor function after spinal cord injury（SCI）when compared with non-primate mammals such as *** limited functional recovery is in part due to a non-permi... 详细信息

关键词： MAG Lateral olfactory tract usher substance protein,an endogenous Nogo receptor antagonist,converts a non-permissive to permissive brain environment for axonal regrowth LOTUS SCI CNS

Improvement of Glacial Lakes Detection under Shadow Environment Using ASTER Data in Himalayas, Nepal

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Chinese Geographical Science 2013年第2期23卷 216-226页

作者： CHEN Wenbo FUKUI Hiromichi DOKO tomoko GU Xingfa Graduate School of Media and Governance Keio University Chubu Institute for Advanced Studies Chubu University Research Institute of Environment and Information Sciences Yokohama National University JSPS Research Fellow Institute of Remote Sensing Applications Chinese Academy of Sciences

The detection of glacial lake change in the Himalayas, Nepal is extremely significant since the glacial lake change is one of the crucial indicators of global climate change in this area, where is the most sensitive area of the global climate changes. In the Hima- layas, some of glacial lakes are covered by the dark mountains＇ shadow because of their location. Therefore, these lakes can not be de- tected by conventional method such as Normalized Difference Water Index （NDWI）, because the reflectance feature of shadowed glacial lake is different comparing to the ones which are located in the open flat area. The shadow causes two major problems： 1） glacial lakes which are covered by shadow completely result in underestimation of the number of glacial lakes; 2） glacial lakes which are partly iden- tified are considered to undervalue the area of glacial lakes. The aim of this study is to develop a new model, named Detection of Shadowed Glacial Lakes （DSGL） model, to identify glacial lakes under the shadow environment by using Advanced Space-borne Ther- mal Emission and Reflection Radiometer （ASTER） data in the Himalayas, Nepal. The DSGL model is based on integration of two dif- ferent modifications of NDWI, namely NDWls model and NDWIshe model. NDWI~ is defined as integration of the NDWI and slope analysis and used for detecting non-shadowed lake in the mountain area. The NDWIshe is proposed as a new methodology to overcome the weakness of NDWI~ on identifying shadowed lakes in highly elevated mountainous area such as the Himalayas. The first step of the NDWIshe is to enhance the data from ASTER 1B using the histogram equalization （HE） method, and its outcome product is named AS- TERho. We used the ASTERhe for calculating the NDWIhc and the NDWIshe. Integrated with terrain analysis using Digital Elevation Model （DEM） data, the NDWIshe can be used to identify the shadowed glacial lakes in the Himalayas. NDWIs value of 0.41 is used to identify the glacier lake （NDWI~ 〉 0.

关键词： glacial lake shadow environment DSGL model ASTER remote sensing Himalayas Nepal

Influence of normal to high stroke volume on congestive heart failure development after transcatheter aortic valve implantation:case series

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Journal of Geriatric Cardiology 2021年第1期18卷 83-88页

作者： tomoko Tomioka Tomohiro Ito Ryokichi Takahasi Shuhei Tanaka Department of Cardiology South Miyagi Medical CenterShibataJapan

Aortic stenosis(AS)is the most common valvular disease in the older adults'population,and its prevalence will likely continue to increase with the aging society.[1]Surgical aortic valve replacement(SAVR)for elderly patients is known as a high-risk procedure.[2-4]Transcatheter aortic valve implantation(TAVI)is a reasonable alternative to SAVR for older and inoperable patients with AS,and TAVI significantly improves outcomes in elderly patients with severe AS and serious comorbidities,[5,6]TAVI achieves a 20%relative reduction in mortality compared with SAVR.

关键词： aortic mortality implantation

Gamete Dialogs in Green Lineages

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Molecular Plant 2015年第10期8卷 1442-1454页

作者： Toshiyuki Mori Hiroko Kawai-Toyooka tomoko Igawa Hisayoshi Nozaki Department of Biological Sciences Graduate School of Science The University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo 113-0033 Japan Graduate School of Horticulture Chiba University 648 Matsudo Matsudo Chiba 271-8510 Japan

Gamete fusion is a core process of sexual reproduction and, in both plants and animals, different sex gametes fuse within species. Although most of the molecular factors involved in gamete interaction are still unknown in various sex-possessing eukaryotes, reports of such factors in algae and land plants have been increasing in the past decade. In particular, knowledge of gamete interaction in flowering plants and green algae has increased since the identification of the conserved gamete fusion factor GENERATIVE CELL SPECIFIC 1/HAPLESS 2 （GCS1/HAP2）. GCSl was first identified as a pollen generative cell-specific transmembrane protein in the lily （Lilium Iongiflorum）, and was then shown to function not only in flowering plant gamete fusion but also in various eukaryotes, including unicellular protists and metazoans. In addition, although initially restricted to Chlamydomonas, knowledge of gamete attachment in flowering plants was also acquired. This review focuses on recent progress in the study of gamete interaction in volvocine green algae and flowering plants and discusses conserved mechanisms of gamete recognition, attachment, and fusion leading to zygote formation.

关键词： sexual reproduction gamete fusion flowering plants green algae evolution

Relative importance of biological and human-associated factors for alien plant invasions in Hokkaido, Japan

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Journal of Plant Ecology 2019年第4期12卷 673-681页

作者： Chika Egawa Takeshi Osawa tomoko Nishida Yasuto Furukawa Institute for Agro-Environmental Sciences National Agriculture and Food Research Organization3-1-3 KannondaiTsukubaIbaraki 305-8604Japan Faculty of Urban Environmental Sciences Tokyo Metropolitan University1-1 Minami-OsawaHachiojiTokyo 192-0397Japan Headquarters National Agriculture and Food Research Organization3-1-1 KannondaiTsukubaIbaraki 305-4517Japan Rakuno Gakuen University 582 Bunkyodai-MidorimachiEbetsuHokkaido 069-8501Japan

Aims The invasion success of alien plants is strongly affected by both biological and human-associated *** of the rela-tive contribution of each factor is important not only for the further understanding of invasion processes but also for the better manage-ment of invasion risk,particularly in protected areas of high con-servation ***,we quantified the relative importance of species biological traits and association with a human activity,***,in explaining the invasion success of alien plants across the entire region and in protected areas in Hokkaido,*** As a quantitative measure of invasion success,the distribution ex-tent of naturalized populations across the entire prefecture and in protected areas was calculated for 63 alien species with equal residence time based on species occurrence records at a spatial resolution of 5-km mesh grid *** each species,we identi-fied seven biological traits(seed mass,dispersal mode,maximum plant height,capability of vegetative reproduction,flowering start time and period and life span)and two human-associated factors(introduction purpose and cultivation frequency for agricultural use).Cultivation frequency was determined based on the frequency of seed-sowing in pastures:(1)not sown,(2)accidentally sown as a seed contaminant and(3)intentionally sown for commercial *** importance of biological traits and human-associated factors in explaining the distribution extent was determined using an information-theoretic *** Findings In explaining the distribution extent across the entire prefecture,species biological traits and human-associated factors showed comparable importance;cultivation frequency exhibited the high-est importance value closely followed by seed mass,maximum height and flowering *** contrast,when focusing on pro-tected areas,human association was more important than bio-logical traits,as indicated by the greatest importance of cultiva

关键词： agricultural use biological invasion distribution nature reserve pasture plants

Enhanced hydrogen production from aqueous methanol solution using TiO2/Cu as photocatalysts

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Frontiers of Chemical Science and Engineering 2014年第2期8卷 197-202页

作者： Paramasivan GOMATHISANKAR tomoko NODA Hideyuki KATSUMATA Tohru SUZUKI Satoshi KANECO Department of Chemistry for Materials Graduate School of Engineering Mie University Mie 514-8507 Japan Environmental Preservation Center Mie University Mie 514-8507 Japan

The photocatalytic hydrogen production from aqueous methanol solution using titanium dioxide （TiO2） was investigated in the addition of metal particles including copper, lead, tin, and zinc. The results show that only the addition of copper particles enhances the hydrogen production. The copper usage and reaction temperature were further optimized for TiO2/Cu photocatalyts. Under the optimal conditions, the hydrogen production using TiO2/Cu as photocatalysts is approxi- mately 68 times higher than that obtained with only TiO2.

关键词： photocatalytic hydrogen generation metha-nol copper particles TiO2 metal-semiconductor interface

AIM associated with the IgM pentamer: attackers on stand-by at aircraft carrier

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Cellular & Molecular Immunology 2018年第6期15卷 563-574页

作者： Toru Miyazaki tomoko Yamazaki Ryoichi Sugisawa M Eric Gershwin Satoko Arai Laboratory of Molecular Biomedicine for Pathogenesis Center for Disease Biology and Integrative MedicineFaculty of MedicineThe University of TokyoTokyo 113-0033Japan CREST Japan Agency for Medical Research and DevelopmentTokyo 113-0033Japan Max Planck-The University of Tokyo Center for Integrative Inflammology Tokyo 113-0033Japan Division of Rheumatology Allergy and Clinical Immunology The University of California School of MedicineDavisCA 95616USA

Circulating immunoglobulin M(IgM)exists in a pentameric form,possessing a polyreactive nature that responds not only to foreign antigens but also to autoantigens;thus,it is involved in both beneficial and detrimental immune responses,including protection from infection and the progression of *** the other hand,IgM also behaves as a carrier of the apoptosis inhibitor of macrophage(AIM)protein,storing a large amount of the inactivated form of AIM in the blood through this *** different disease conditions,AIM can dissociate from IgM locally or systemically to exert its function,inducing the removal of various biological debris such as excess fat,bacteria,cancer cells or dead cell *** typically,upon induction of acute kidney injury(AKI),IgM-free AIM is filtered by the glomerulus in the kidney,which stimulates the clearance of intraluminal dead cells debris at the obstructed proximal tubules,thereby facilitating the repair of kidney ***,cats exhibit a deficiency in AIM release from IgM,which may increase their susceptibility to renal ***,association with AIM inhibits IgM binding to the Fcα/μreceptor on follicular dendritic cells at the splenic germinal center,thereby protecting the IgM immune complex from Fcα/μreceptor-mediated internalization,which supports IgM-dependent antigen presentation to B cells and stimulates high-affinity IgG antibody *** regulation of AIM–IgM binding,resulting from the discovery of reciprocal actions between AIM and IgM,could lead to the development of novel therapies against different diseases.

关键词： apoptosis inhibitor of macrophage(AIM) immunoglobulin M(IgM) acute kidney injury(AKI) hepatocellular carcinoma(HCC) cat renal failure

Treating bilio-duodenal obstruction: Combining new endoscopic technique with 6 Fr stent introducer

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World Journal of Gastroenterology 2010年第22期16卷 2828-2831页

作者： Iruru Maetani tomoko Nambu Shigefumi Omuta Takeo Ukita Hiroaki Shigoka Division of Gastroenterology Department of Internal Medicine Toho University Ohashi Medical Center

Periampullary cancer may cause not only biliary but also duodenal obstructions. In patients with concomitant duodenal obstructions, endoscopic biliary stenting remains technically difficult and may often require percutaneous transhepatic biliary drainage. We describe a method of metal stent placement via a thin forwardviewing endoscope in patients with simultaneous biliary and duodenal obstruction. In two consecutive patients with biliary and duodenal obstruction due to pancreatic cancer, a new biliary metal stent mounted in a slim delivery catheter was placed via a thin forward viewing endoscope after passage across the duodenal stenosis without balloon dilation. In both patients, with our new placement technique, metallic stents were successfully placed in a short time without adverse events. After biliary stenting, one patient received curative resection and the other received duodenal stenting for palliation. Metallic stent placement with a forward-viewing thin endoscope is a beneficial technique, which can avoid percutaneous drainage in patients with bilio-duodenal obstructions due to periampullary cancer.

关键词： Biliary obstruction Duodenal obstruction Pancreatic cancer Self-expandable metallic stent Stent placement Thin forward-viewing endoscope

PENALIZED LEAST SQUARE IN SPARSE SETTING WITH CONVEX PENALTY AND NON GAUSSIAN ERRORS

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Acta Mathematica Scientia 2021年第6期41卷 2198-2216页

作者： Doualeh ABDILLAHI-ALI Nourddine AZZAOUI Arnaud GUILLIN Guillaume LE MAILLOUX tomoko MATSUI Laboratoire de Mathématiques Blaise Pascal CNRS-UMR 6620Université Clermont-Auvergne(UCA)63000Clermont-FerrandFrance Department of Statistical Modeling Institute of Statistical Mathematics10-3 Midori-choTachikawa-shiTokyo1908562Japan

This paper consider the penalized least squares estimators with convex penalties or regularization *** provide sparsity oracle inequalities for the prediction error for a general convex penalty and for the particular cases of Lasso and Group Lasso estimators in a regression *** main contribution is that our oracle inequalities are established for the more general case where the observations noise is issued from probability measures that satisfy a weak spectral gap(or Poincaré)inequality instead of Gaussian *** illustrate our results on a heavy tailed example and a sub Gaussian one;we especially give the explicit bounds of the oracle inequalities for these two special examples.

关键词： penalized least squares Gaussian errors convex penalty

Alphonse Mucha 1860-1939

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