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Recent Progress in Plasma Control Studies on the Improvement of Plasma Performance in Heliotron J

Plasma Science and Technology 2011年第1期13卷 21-25页

作者： Tohru MIZUUCHI Kazunobu NAGASAKI Hiroyuki OKADA Shinji KOBAYASHI Satoshi YAMAMOTO Takashi MINAMI Shinsuke OHSHIMA Masaki TAKEUCHI Kiyofumi MUKAI Hyunyong LEE Linge ZANG Kohta NOMURA Masashige SUWA Kento YAMAMOTO Hiroaki YASHIRO Hayao YOSHINO Shouhei ARAI Tasuku KAGAWA Takayuki MINAMI Kouji MIZUNO Yoshinobu WADA Hiroto WATADA Nobuhiro NISHINO Yosuke NAKASHIMA Kiyoshi HANATANI Yuji NAKAMURA Shigeru KONOSHIMA Fumimichi sano Institute of Advanced Energy Kyoto Univ. Kyoto University Pioneering Research Unit for Next Generation Graduate School of Energy Science Kyoto University Graduate School of Engineering Hiroshima University Plasma Research Center University of Tsukuba

Recent progress in plasma control studies on the improvement of plasma performance in Heliotron J is reviewed. The supersonic molecular beam injection （SMBI） fueling is successfully applied to Heliotron J plasma. A supersonic H2-beam is effectively injected to increase fueling efficiency and generate a peaked density profile. Local fueling with a short-pulsed SMBI can increase the core plasma density and avoid the degradation arising from edge cooling. Second harmonic electron cyclotron current drive （ECCD） experiments were conducted by launching a focused Gaussian beam with a parallel refractive index of -0.05 ≤ Nil 〈 0.6. Results show that the electron cyclotron （EC） driven current is determined not only by Nil but also by local magnetic field （B） structure where the EC power is deposited. Detailed analysis of the observed NI and B dependences is in progress with a ray-tracing simulation using the TRAVIS code. Fast ion velocity distribution was investigated using fast protons generated by ion cyclotron resonant frequency （ICRF） minority heating. For the standard configuration in Heliotron J, charge ex- change neutral particle analysis （CX-NPA） measurements show higher effective temperature of fast minority protons in the on-axis resonance case compared to that in the HFS （high field side） off-axis resonance case. However, the increase in bulk ion temperature in the HFS resonance case is larger than that in the on-axis resonance.

关键词： plasma control. Heliotron J improved confinement ECH/ECCD NBI ICRF. minority heating fueling control

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Quantification of Neutron andγRay Fields for Subcriticality Determination(2)

Quantification of Neutron andγRay Fields for Subcriticality...

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作者： Y.Nauchi T.Kameyama H.Unesaki T.Misawa T.sano T.Yagi Central Research Institute of Electric Power Industry

INTRODUCTION:In order to observe linear relation between the subcritical multiplication factor k and yield ratio of y rays to neutrons,measurement techniques of total yields of both radiations have been *** of fission y rays and neutron absorptions outside subcritical cores had been conducted. EXPERIMENTS:4 subcritical cores which consist of C35 assemblies(4,3,2 rows x 2 columns and 2 rows x 1.5 column) were mocked up as shown in *** cores were driven by a Cf source of 1.3 x 10 Bq in-

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High-throughput simple sequence repeat (SSR) markers development for the kelp grouper (<i>Epinephelus bruneus</i>) and cross-species amplifications for Epinephelinae species

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Advances in Bioscience and Biotechnology 2014年第2期5卷 117-130页

作者： Satoshi Kubota Qi Liu Kanonkporn Kessuwan Nobuaki Okamoto Takashi Sakamoto Yoji Nakamura Yuya Shigenobu Takuma Sugaya Motohiko sano Susumu Uji Kazuharu Nomura Akiyuki Ozaki Faculty of Marine Science Tokyo University of Ma-rine Science and Technology Tokyo Japan Faculty of Marine Science Tokyo University of Ma-rine Science and Technology Tokyo Japan National Research Institute of Fisheries Science Fi-sheries Research Agency Kanagawa Japan National Research Institute of Aquaculture Fisheries Research Agency Mie Japan National Research Institute of Fisheries Science Fi-sheries Research Agency Kanagawa Japan

The kelp grouper (Epinephelus bruneus), belonging to one of the largest genera among the subfamily Epinephelinae, is a commercially important fish in Japan. There are limited data about the genomics of this species. To provide tools for addressing both population genetics studies and gene mapping, dito pentanucleotide simple sequence repeat (SSR) markers were developed using 454 pyrosequencing. Among the 1466 SSR markers developed, 1244 primer sets produced strong PCR products, of which 905 (72.7%) were polymorphic in kelp grouper. Cross-species utility of the 905 polymorphic SSR markers was tested in four additional Epinephelinae species of Hyporthodus septemfasciatus, Plectropomus leopardus, Epinephelus lanceolatus and Epinephelus coioides. Results revealed that, respectively, 401 (44.3%), 136 (15.0%), 434 (49.0%) and 538 (59.4%) SSRs showed specific polymorphic products. Of these, 40 SSR markers (33 di-, 1 tri- and 6 tetra-nucleotides) showed polymorphism in all species tested. Additionally, three AGAT SSR motifs which accounted for 42.9% of the nondi-nucleotide markers were found in the 40 SSR markers. This indicates that the AGAT SSR motif has a high potential as a highly versatile SSR marker in grouper Epinephelinae. The SSR markers developed in this study can be employed to obtain reliable genetic variability estimates for groupers (Epinephelinae).

关键词： Kelp Grouper Epinephelus bruneus Repeat Motif Simple Sequence Repeat (SSR) 454 Pyrosequencing Cross-Species Amplification

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中国栽培葡萄上发生的类病毒的种类鉴定

中国栽培葡萄上发生的类病毒的种类鉴定

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第三次全国植物病毒和病毒防治学术研讨会

作者：李世访王晶 sano Teruo 中国农业科学院植物保护研究所植物病虫害生物学国家重点实验室 Laboratory of Plant pathology Faculty of Agriculture and Life ScienceHirosaki UniversityHirosaki 036-8561japan

在国外,葡萄上已经报道了有5种类病毒,它们分别是啤酒花矮化类病毒葡萄株系(hop stunt vi-roid,HSVd-g)、柑橘裂皮类病毒葡萄株系(citrus-exocortis viroid,CEVd-g)、葡萄黄疸类病毒(grapevine yellow speckle viroid-1 or 2,GYSVd 1 or 2)以及澳大利亚葡萄类病毒(Australia grapevine vi-roid,AGVd)。HSVd-g和啤酒花矮化类病毒(HSVd)在序列上仅有一个碱基的差异,在葡萄上

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An Absolute Standardized Uptake Value Is More Useful than the Decreased Rate of Uptake of FDG-PET to Predict Responses to Neoadjuvant Chemoradiotherapy for Esophageal Cancer

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Open Journal of Gastroenterology 2016年第11期6卷 373-385页

作者： Masanobu Nakajima Hiroyuki Kato Tatsuya Miyazaki Takanori Inose Naritaka Tanaka Shigemasa Suzuki Takehiko Yokobori Makoto Sakai Akihiko sano Keisuke Ieta Makoto Sohda Minoru Fukuchi Hiroyuki Kuwano Department of Surgery I Dokkyo Medical University Mibu Japan Department of General Surgical Science Gunma University Graduate School of Medicine Maebashi Japan

Background: Neoadjuvant chemoradiotherapy (CRT) is frequently performed for esophageal squamous cell carcinoma. In this study, we retrospectively assessed the standardized uptake value (SUV) of FDG-PET against decreased rates of SUV to assess the response of advanced esophageal squamous cell carcinoma patients to neoadjuvant CRT, and the correlation of this response with histopathological findings. Patients and Methods: Thirty-three patients receiving CRT followed by surgery were analyzed. Results: Using the decreased rate of maximum SUV, the sensitivity and specificity in distinguishing complete responders (CR) from non-CR patients was 63% and 44%. Using the maximum SUV before surgery, the sensitivity and specificity for distinguishing pathological CR from non-CR was 88% and 56%. Conclusions: To identify complete responders of CRT for esophageal cancer, absolute maximum SUV value is a better predictor than decreased rate of the maximum SUV.

关键词： Esophageal Cancer Neoadjuvant Therapy Chemoradiotherapy FDG-PET SUV

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逆向抽吸减压法在颈内动脉大型及巨大型动脉瘤夹闭术中的应用

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中华神经外科杂志 2011年第8期27卷 788-791页

作者：陈四方王占祥 Yoko Kato Hirotoshi sano 陈陆馗谭国伟郭剑峰陈东汉厦门大学附属第一医院神经外科 361003 Department of Neurosurgery Fujita Health University Hospital Toyoake Japan 厦门大学附属中山医院神经外科

目的探讨逆向抽吸减压法在颈内动脉大型及巨大型动脉瘤夹闭术中的优点及其风险。方法回顾性分析逆向抽吸减压法在26例颈内动脉大型及巨大型动脉瘤夹闭术中的应用及疗效。结果26例动脉瘤术中均成功夹闭，术后3D—CTA或DSA复查均提示动脉... 详细信息

目的探讨逆向抽吸减压法在颈内动脉大型及巨大型动脉瘤夹闭术中的优点及其风险。方法回顾性分析逆向抽吸减压法在26例颈内动脉大型及巨大型动脉瘤夹闭术中的应用及疗效。结果26例动脉瘤术中均成功夹闭，术后3D—CTA或DSA复查均提示动脉瘤完全夹闭，载瘤动脉通畅，术后均未出现植物生存状态或死亡。结论逆向抽吸减压法在颈内动脉大型及巨大型动脉瘤夹闭术中能有效地缩小动脉瘤的体积，有利于动脉瘤的剥离和夹闭方案。

关键词：动脉瘤颈内动脉逆向抽吸减压法

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脂多糖和干扰素-γ拮抗吗啡,anandamide,和雌激素诱导的人心房内皮iNOS的表达(英文)

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Acta Pharmacologica Sinica 2000年第5期21卷 23-27页

作者： Caterina FIMIANI,Harold MAGAZINE,Ingeborg D WELTERS,Thomas V BILFINGER,Felice SAL-sano,Else TONNESEN,George B STEFANO Neuroscience Research Institute State University of New York College at Old Westbury Old Westbury NY 11568 USA Queens College and Graduate School of the City University of New York Flushing New York 11367 USA Neuroscience Research Institute State University of New York College at Old Westbury Old Westbury NY 11568 USA Neuroscience Research Institute State University of New York College at Old Westbury Old Westbury NY 11568 USA Division of Cardiothoracic Surgery Department of Surgery State University of New York College at Stony Brook Stony Brook NY 11794 USA Clinical Medicine Department La Sapienza University Rome Italy Department of Anesthesia Aarhus Kommunehospital Denmark Neuroscience Research Institute State University of New York College at Old Westbury Old Westbury NY 11568 USA Division of Cardiothoracic Surgery Department of Surgery State University of New York College at Stony Brook Stony Brook NY 11794 USA

AIM: To determine whether inducible nitric oxide syn-thase (iNOS) stimulation of human atrial fragments can be diminished by the naturally occurring signal molecules, such as morphine, anandamide, and estrogen . The use of iNOS as an indicator is justified since it has been associated with initiation of various types of cellular damage either directly or indirectly. METHODS: Western blots were performed on control and drug-exposed atrial tissue before and after lipopolysaccharide (LPS) and interferon-γ (IFN-γ) exposure. RESULTS: Preincubation of the tissue with morphine, anandamide or estrogen prior to, but not after, the addition of LPS + IFN-γ, blocked iNOS expression. The nitric oxide donor SNAP also blocked iNOS induction while preincubation of atrial fragments with an inhibitor of NOS, L-NAME, prior to morphine or anandamide exposure, restored LPS + IFN-γ induction of iNOS. CONCLUSION : These data suggest a direct regulatory link at the transcriptional level between constitutive (c) NOS and iNO

关键词：一氧化氮吗啡 anandamide 雌激素类一氧化氮合酶人类心房内皮

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利用常间回文重复序列丛集介导的基因编辑评估Tet2和甲基转移酶3a在克隆性造血和心血管病中的作用

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中华高血压杂志 2018年第7期26卷 699-699页

作者： sano S Ohshima K Wang Y Katanasaka Y sano M Walsh K 刘青叶鹏

克隆性血细胞生成与死亡率、心血管病发生率增加有关。这种情况可能是由于造血干/祖细胞（hematopoietic stem/progenitor cells,HSPC）内的前白血病驱动基因的体细胞突变引起的。大约有40个候选驱动基因已被确定出来,但有研究证明在这... 详细信息

克隆性血细胞生成与死亡率、心血管病发生率增加有关。这种情况可能是由于造血干/祖细胞（hematopoietic stem/progenitor cells,HSPC）内的前白血病驱动基因的体细胞突变引起的。大约有40个候选驱动基因已被确定出来,但有研究证明在这些基因中,仅一个基因[10-11易位-2（TET2）]的突变在大鼠模型中可导致心血管病。

关键词：克隆性造血心血管病甲基转移酶基因重复序列造血干/祖细胞体细胞突变评估

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脾切除在近端胃癌全胃切除术中的意义：一项随机对照研究

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中华胃肠外科杂志 2017年第1期20卷 72-72页

作者： sano T 聂润聪赵百伟不详中山大学附属肿瘤医院

目的：本研究旨在阐明脾切除在近端胃癌全胃切除术中的意义。背景：在全胃切除术中，脾切除不仅提高了手术并发症及病死率，而且其生存获益也尚未明确。既往随机对照试验的检验功效不足，证据不确凿。方法：本研究为一项随机对照试验。... 详细信息

目的：本研究旨在阐明脾切除在近端胃癌全胃切除术中的意义。背景：在全胃切除术中，脾切除不仅提高了手术并发症及病死率，而且其生存获益也尚未明确。既往随机对照试验的检验功效不足，证据不确凿。方法：本研究为一项随机对照试验。选择人组未侵犯大弯侧的T2-4N0-2M0的近端胃腺癌患者作为研究对象，并被随机分组到脾切除组或脾保留组。手术过程中，手术医生确保R0切除和灌洗细胞学阴性。本研究的主要研究终点是总生存率，

关键词：全胃切除术近端胃癌脾切除随机对照研究随机对照试验手术并发症检验功效随机分组

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Analytical modelling of the expansion of a solid obstacle interacting with a radiative shock

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High Power Laser Science and Engineering 2018年第2期6卷 123-132页

作者： Th.Michel E.Falize B.Albertazzi G.Rigon Y.Sakawa T.sano H.Shimogawara R.Kumar T.Morita C.Michaut A.Casner R Barroso P.Mabey Y.Kuramitsu S.Laffite L.Van Box Som G.Gregori R.Kodama N.Ozaki P.Tzeferacos D.Lamb M.Koenig luli-cnrs ecole polytechniquecea:universite paris-saclayupmc univ paris 06:sorbonne universites-f-91128 palaiseau cedexFrance cea damdifF-91297 ArpajonFrance cea saclay dsm/irfu/service d'astrophysiqueF-91191 Gif-sur-YvetteFrance institute of laser engineering osaka universitySuitaOsaka 565-0871Japan faculty of engineering sciences kyushu university6-1 Kasuga-KoenKasugaFukuoka 816-8580Japan luth observatoire de parispsl research universitycnrsuniversite paris diderotSorbonne Paris Cite92190 MeudonFrance universite de bordeaux-cnrs-cea celia UMR 5107F-33405 TalenceFrance gepi observatoire de parispsl research universitycnrsuniversite paris diderotSorbonne Paris Cite75014 ParisFrance graduate school of engineering osaka universitySuitaOsaka 565-0871Japan lerma observatoire de parispsl research universitycnrssorbonne universitesUPMC Univ.Paris 06F-75005 ParisFrance clarendon laboratory university of oxfordParks RoadOxford OX1 3PUUK flash center for computational science university of chicagoIL 60637USA

In this paper, we present a model characterizing the interaction of a radiative shock(RS) with a solid material, as described in a recent paper(Koenig et al., Phys. Plasmas, 24, 082707(2017)), the new model is then related to recent experiments performed on the GEKKO XII laser facility. The RS generated in a xenon gas cell propagates towards a solid obstacle that is ablated by radiation coming from the shock front and the radiative precursor, mimicking processes occurring in astrophysical phenomena. The model presented here calculates the dynamics of the obstacle expansion,which depends on several parameters, notably the geometry and the temperature of the shock. All parameters required for the model have been obtained from experiments. Good agreement between experimental data and the model is found when spherical geometry is taken into account. As a consequence, this model is a useful and easy tool to infer parameters from experimental data(such as the shock temperature), and also to design future experiments.

关键词： high energy density physics laser–plasmas interaction modelling plasmas astrophysics plasma physics radiative hydrodynamics radiative shock

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