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Unexpectedly Good Neurological Outcome after Prolonged Cardiac Arrest

Open Journal of Emergency Medicine 2019年第1期7卷 1-7页

作者： Kohei Ichinohashi tomoaki natsukawa Takahiro Ueda Hirotaka Sawano Yasuyuki Hayashi Hironori Shigeoka Yasuhide Kitazawa Atsushi Hiraide Department of Emergency and Critical Care Medicine Faculty of Medicine Kindai University Osaka Japan

Backgoround: Generally, neurological outcome of patients who have achieved return of spontaneous circulations (ROSC) with abnormal blood tests date and some severe organ complications is extremely poor. Because we experienced a case of good neurological outcome using two different types of extracorporeal membrane oxygenation (ECMO) in spite of prolonged cardiac arrest, we reported this case and reviewed the literature. Case presentation: A 36-year-old male suddenly collapsed at bar after drinking. Initial ECG showed ventricular fibrillation (VF) and subsequently underwent advanced cardiovascular life support. On admission, the ECG still showed VF, but pupillary light reflex was faintly present. Then, veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support was established 54 minutes after collapse. Blood tests showed lactate was 15.8 mmol/l and NH3 of 251 μg/dl. To improve respiratory function after cardiogenic shock, we changed to veno-venous ECMO (VV-ECMO) and removed superabundant fluid using continuous hemodiafiltration. Patient was discharged on day-26 after a full functional recovery. Conclusion: In severe respiratory disorder, it would be more effective to change to VV-ECMO after recovering from cardiogenic shock while removing superabundant fluid using continuous hemodiafiltration. In predicting the neurological outcome of a post cardiac arrest patient, the presence of a pupillary light reflex may be more significant than NH3 and lactate.

关键词： Cardiac Arrest Extracorporeal Membrane Oxygenation (ECMO) Neurological Outcome

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Exploration behavior of group-in-a-box layouts

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Visual Informatics 2019年第1期3卷 38-47页

作者： Yuki Ueno Hiroaki natsukawa Nozomi Aoyama Koji Koyamada Department of Electrical Engineering Kyoto UniversityKyotoJapan Academic Center for Computing and Media Studies Kyoto UniversityKyotoJapan

To improve visualization,it is necessary to optimize the design by analyzing the behavior of users as well as improving the evaluation index of the computational experiment and the task performance(e.g.,the correct answer rate and completion time)in the user *** various studies have investigated the influence of user behavior on the evaluation of visualization,majority of these studies focused on simple visualization tasks.A simple task does not indicate a simple visualization comprising a few visualization elements but a task in which the information obtained from visualization is the only clue for completing the ***,a few studies have targeted complicated tasks in which multiple information obtained from visualization is considered to be a clue for completing the task regardless of the number of elements that are contained in the ***,in this study,we investigated the behavior of the participants who have performed complicated *** selected two types of group-in-a-box(GIB)layouts,which can be considered to be a complicated visualization method,as the target of the user *** the user experiment,participants were asked to perform an exploration task specific to GIB layouts;which group has the maximum number of intra-edges?We also collected the eye-tracking data in addition to task *** results showed that the correct answer rate is considerably affected by the visualization factor;whether the correct answer,the box with maximum number of intra-edges,is the box with the largest ***,an analysis of the collected eye-tracking data revealed that this visualization factor affected the exploration behavior of the participants;however,it did not affect the location at which the participants were focused *** obtained results indicated that the visualization elements that were not considered by the visualization designer can influence the task of extracting information from the ***

关键词： Visual search Eye-tracking Group-in-a-box layout

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A visual analytics system to support the formation of a hypothesis from calcium wave data

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Visual Informatics 2018年第1期2卷 2-13页

作者： Kozen Umezawa Hiroaki natsukawa Yosuke Onoue Koji Koyamadab Department of Electrical Engineering Graduate School of EngineeringKyoto UniversityKyotoJapan Academic Center for Computing and Media Studies Kyoto UniversityKyotoJapan Advanced Research Center for the Promotion of Interdisciplinary Education and Research Kyoto UniversityKyotoJapan

In most species,calcium waves in the oocyte are considered common phenomena in the activation of ***,the mechanism of calcium waves has not yet been *** collaborating with biologists studying Caenorhabditis elegans(***),which is widely used as a model organism,we observed that the following requirements must be satisfied to form a useful hypothesis based on calcium waves captured using high-speed in vivo imaging:(1)the ability to obtain an overview of how the calcium waves are propagated and(2)the ability to understand the propagation of waves in a narrow ***,conventional visualization methods cannot satisfy these requirements ***,we propose a visual analytics system that allows users to understand and explore calcium wave images using cross-correlation analysis of the time-series data of the Ca^(2+)fluorescence intensity at each *** interface of this system comprises an overview visualization,a detail visualization,and user interactions to satisfy these requirements and realize exploratory *** views present an overview visualization that displays the clustering results of a directed graph calculated using cross-correlation *** views enable the users to understand the overview of wave propagation,thereby helping users find a region of *** detail visualization shows the relationship between the region of interest and other ***,users can use the proposed system with overview-detail and brush-link exploration to assign meaning to the region of interest and construct a hypothesis for its *** this paper,we demonstrate how the proposed visual analytics approach works and how new hypotheses can be formed using the analysis of *** calcium waves.

关键词： Visual Knowledge Discovery Time Series Data Bioinfonnatics Visualization

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