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Journal of Systems Science and Systems Engineering 2007年第1期16卷 34-49页

作者： Kenichi horie Yoshiharu MAENO Yukio OHSAWA School of Engineering the University of Tokyo Graduate School of System Management the University of Tsukuba maeno

It is only the observable part of the real world that can be stored in data. For such incomplete and ill-structured data, data crystallizing aims at presenting the hidden structure among events including unobservable events. This is realized by data crystallization, where dummy items, corresponding to potential existence ofunobservable events, are inserted to the given data. These dummy items and their relations with observable events are visualized by applying KeyGraph to the data with dummy items, like the crystallization of snow where dusts are involved in the formation of crystallization of water molecules. For tuning the granularity level of structure to be visualized, the tool of data crystallization is integrated with human＇s process of understanding significant scenarios in the real world. This basic method is expected to be applicable for various real world domains where previous methods of chance-discovery lead human to successful decision making. In this paper, we apply the data crystallization with human-interactive annealing （DCHA） to the design of products in a real company. The results show its effect to industrial decision making.

关键词： Chance discovery data crystallization unobservable events human machine interaction,design

High-temperature formation phases and crystal structure of hot-pressed thermoelectric compounds with chalcopyrite-type structure

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Rare Metals 2018年第4期37卷 360-368页

作者： Atsuko Kosuga Yosuke Fujii Akito horie Department of Physical Science Graduate School of ScienceOsaka Prefecture University JST PRESTO Department of Electronics Mathematics and PhysicsGraduate School of EngineeringOsaka Prefecture University

In this study, we introduced the temperaturedependent formation phases and crystallographic parameters of hot-pressed silver gallium telluride AgGaTe2 and copper gallium telluride CuGaTe2 with chalcopyrite structure from 300 to 800 K. These two compounds are potential thermoelectric materials in the intermediate temperature range; however, the temperature-dependent formation phases and crystallographic parameters of hotpressed samples have not yet been analyzed in detail. The crystal structure analysis based on synchrotron X-ray diffraction （SXRD） measurements clarifies that impurity phases such as Te and Ag2Te in the AgGaTe2 matrix and Te and CuTe in the CuGaTe2 matrix appear at some temperature regions above 300 K. The existence of such impurity phases could be correlated with the increases of the electrical resistivity and Seebeck coefficient of the samples after multiple measurement cycles of the temperature-dependent transport properties from 300 to 800 K. The tetragonal lattice parameters a and c, tetragonal lattice volume, thermal expansion coefficients, tetragonal distortion, anion displacement parameter, and isotropic displacement parameter of the hot-pressed AgGaTe2 and CuGaTe2 were also analyzed. These crystallographic parameters are expected to substantially affect the thermoelectric properties of AgGaTe2 and CuGaTe2. Our results provide prospect of the long-term high-temperature stability and clues of the detailed analysis on the transport properties of hot-pressed AgGaTe2 and CuGaTe2, which should aid their development for thermoelectric applications.

关键词： Chalcopyrite Silver gallium telluride Coppergallium telluride Thermoelectric Crystal structure

Intraoperative glycemic control procedures and the use of an artificial pancreas

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World Journal of Gastroenterology 2009年第33期15卷 4126-4131页

作者： Koichi Yamashita tomoaki Yatabe Department of Anesthesiology and Critical Care Medicine Kochi Medical School

Strict intraoperative glycemic control can significantly decrease the incidence of postoperative infection; however, anesthesiologists must carefully control blood glucose levels as well as properly manage the respiratory and cardiovascular systems. However, standard blood glucose measurement systems and insulin dosing algorithms, which are necessary for achieving strict glycemic control, have not yet been developed. An artificial pancreas (STG-22TM; Nikkiso Co., Tokyo, Japan) is considered a highly accurate blood glucose monitoring system capable of closed-loop control of blood glucose. The device has, however, many problems to be addressed since it is a large and expensive system with little versatility, and it requires a large amount of blood to be collected. Therefore, the development of less invasive and inexpensive systems with future technological progress is greatly anticipated.

关键词： Strict glycemic control Artificial pancreas Anesthesiologist Sliding scale

Multi-Class Sentiment Analysis on Twitter: Classification Performance and Challenges

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Big Data Mining and Analytics 2019年第3期2卷 181-194页

作者： Mondher Bouazizi tomoaki Ohtsuki Department of Information and Computer Science Keio UniversityYokohama 223-8542Japan

Sentiment analysis refers to the automatic collection,aggregation,and classification of data collected online into different emotion *** most of the work related to sentiment analysis of texts focuses on the binary and ternary classification of these data,the task of multi-class classification has received less ***-class classification has always been a challenging task given the complexity of natural languages and the difficulty of understanding and mathematically"quantifying"how humans express their *** this paper,we study the task of multi-class classification of online posts of Twitter users,and show how far it is possible to go with the classification,and the limitations and difficulties of this *** proposed approach of multi-class classification achieves an accuracy of 60.2%for 7 different sentiment classes which,compared to an accuracy of 81.3%for binary classification,emphasizes the effect of having multiple classes on the classification ***,we propose a novel model to represent the different sentiments and show how this model helps to understand how sentiments are *** model is then used to analyze the challenges that multi-class classification presents and to highlight possible future enhancements to multi-class classification accuracy.

关键词： Twitter sentiment analysis machine learning

Discrete Circular Distributions with Applications to Shared Orthologs of Paired Circular Genomes

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Computer Modeling in Engineering & Sciences 2020年第6期123卷 1131-1149页

作者： tomoaki Imoto Grace S.Shieh Kunio Shimizu School of Management and Information University of ShizuokaShizuokaJapan Institute of Statistical Science Academia SinicaTaipeiTaiwan School of Statistical Thinking The Institute of Statistical MathematicsTokyoJapan

For structural comparisons of paired prokaryotic genomes,an important topic in synthetic and evolutionary biology,the locations of shared orthologous genes(henceforth orthologs)are observed as binned *** and other data,e.g.,wind directions recorded at monitoring sites and intensive care unit arrival times on the 24-hour clock,are counted in binned circular arcs,thus modeling them by discrete circular distributions(DCDs)is *** propose a novel method to construct a DCD from a base continuous circular distribution(CCD).The probability mass function is defined to take the normalized values of the probability density function at some pre-fixed equidistant points on the *** families of constructed DCDs which have normalizing constants in closed form are *** studies show that DCDs outperform the corresponding CCDs in modeling grouped(discrete)circular data,and minimum chi-square estimation outperforms maximum likelihood estimation for *** apply the constructed DCDs,invariant wrapped Poisson and wrapped discrete skew Laplace to compare the structures of paired bacterial ***,discrete four-parameter wrapped Cauchy(nonnegative trigonometric sums)distribution models multi-modal shared orthologs in Clostridium(Sulfolobus)better than the others considered,in terms of AIC and Freedman’s goodness-of-fit *** result that different DCDs fit the shared orthologs is consistent with the fact they belong to two ***,these prokaryotes have a common favored site around 70°on the unit circle;this finding is important for building synthetic prokaryotic genomes in synthetic *** DCDs can also be applied to other binned circular data.

关键词： Bacterial genomes circular distribution goodness-of-fit test modeling synthetic and evolutionary biology.

How do Plants Organize Microtubules Without a Centrosome?

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Journal of Integrative Plant Biology 2007年第8期49卷 1154-1163页

作者： TakashiMurata TakakoTanahashi tomoaki Nishiyama Kazuo Yamaguchi Mitsuyasu Hasebe National Institute for Basic Biology Okazaki 444-8585Japan Department of Basic BiologyThe Graduate University for Advanced StudiesOkazaki 444-8585Japan Advanced Science Research Center Kanazawa UniversityTakaramachi 13-1Kanazawa 920-0934Japan ERATOJapan Science and Technology AgencyTakaramachi 13-1Kanazawa 920-0934Japan Advanced Science Research Center Kanazawa UniversityTakaramachi 13-1Kanazawa 920-0934Japan Graduate School of Natural Science and TechnologyKanazawa UniversityKanazawa 920-1192Japan National Institute for Basic Biology Okazaki 444-8585Japan Department of Basic BiologyThe Graduate University for Advanced StudiesOkazaki 444-8585Japan ERATOJapan Science and Technology AgencyOkazaki 444-8585Japan

A microtubule nucleates from a γ-tubuUn complex, which consists of γ-tubulin, proteins from the SPC971SPC98 family, and the WD40 motif protein GCP-WD. We analyzed the phylogenetic relationships of the genes encoding these proteins and found that the components of this complex are widely conserved among land plants and other eukaryotes. By contrast, the interphase and mitotic arrays of microtubules in land plants differ from those in other eukaryotes. In the interphase cortical array, the majority of microtubules nucleate on existing microtubules in the absence of conspicuous microtubule organizing centers （MTOCs）, such as a centrosome. During mitosis, the spindle also forms in the absence of conspicuous MTOCs. Both poles of the spindle are broad, and branched structures of microtubules called microtubule converging centers form at the poles. In this review, we hypothesize that the microtubule converging centers form via microtubule-dependent microtubule nucleation, as in the case of the interphase arrays. The evolutionary insights arising from the molecular basis of the diversity in microtubule organization are discussed.

关键词： cortical microtubules evolution γ-tubulin microtubule nucleation mitotic spindle.

Direct numerical simulation of elastic turbulence and its mixing-enhancement effect in a straight channel flow

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Chinese Physics B 2013年第2期22卷 320-327页

作者：张红娜李凤臣曹阳 Kunugi tomoaki 宇波 School of Energy Science and Engineering Harbin Institute of Technology Department of Nuclear Engineering Kyoto University Beijing Key Laboratory of Urban Oil and Gas Distribution Technology China University of Petroleum-Beijing

In this paper,we present a direct numerical simulation（DNS） of elastic turbulence of viscoelastic fluid at vanishingly low Reynolds number（Re = 1） in a three-dimensional straight channel flow for the first time,using the Giesekus constitutive model for the *** order to generate and maintain the turbulent fluid motion in the straight channel,a sinusoidal force term is added to the momentum equation,and then the elastic turbulence is numerically realized with an initialized chaotic velocity field and a stretched conformation *** and structural characteristics of the elastic turbulence therein are analyzed based on the detailed information obtained from the *** fluid mixing enhancement effect of elastic turbulence is also demonstrated for the potential applications of this phenomenon.

关键词： elastic turbulence viscoelastic fluid direct numerical simulation mixing enhancement

Acute respiratory distress syndrome associated with severe ulcerative colitis

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World Journal of Gastroenterology 2010年第19期16卷 2440-2442页

作者： Shiho Sagara Yasuo horie Yumiko Anezaki Hideaki Miyazawa Masahiro Iizuka Health Care Center Akita Red Cross Hospital Akita 010-0001 Japan Department of Internal Medicine Akita University School of Medicine Akita 010-8543 Japan Department of Surgery Akita University School of Medicine Akita 010-8543 Japan

Various extraintestinal manifestations including pulmonary abnormalities have been reported in patients with ulcerative colitis. Acute respiratory distress syndrome (ARDS) is a serious and fatal pulmonary manifestation. We have experienced a 67-year-old male patient with ARDS associated with a severe type of ulcerative colitis (UC). Severe dyspnea symptoms occurred during the treatment of UC in a previous hospital and the patient was transferred to our hospital on June 27, 2007. Both blood and sputa cultures for bacteria and fungi were negative. Cytomega-lovirus antigenemia was also not detected. From the clinical and radiological [Chest X-ray, computed tomography (CT)] findings, the patient was diagnosed with ARDS on the basis of the def inition of ARDS developed by the European-American Consensus Conference on ARDS. Both colonic inflammations and ARDS symptoms of the patient were resistant to any medical treatment includingcorticosteroids and antibiotics. However, ARDS symptoms were dramatically improved after surgical colectomy. We believe that severe colonic inflammation from UC was closely associated with the onset of ARDS of the patient. Our case report suggests that a severe type of ulcerative colitis might be taken into consideration as one of the predisposing factors of ARDS.

关键词： Acute respiratory distress syndrome Ulcerative colitis Inflammatory bowel disease Extra-intestinal manifestation

Effects of Asian dust events on atmospheric bacterial communities at different distances downwind of the source region

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Journal of Environmental Sciences 2018年第10期30卷 133-139页

作者： Jonguk Park Pin-Fang Li tomoaki Ichijo Masao Nasu Nobuyasu Yamaguchi Graduate School of Pharmaceutical Sciences Osaka University1-6 Yamada-okaSuitaOsaka 565-0871Japan National Institutes of Biomedical Innovation Health and Nutrition7-6-8 Asagi Saito Ibaraki Osaka 567-0085 Japan College of Resources and Environmental Sciences China Agricultural University Beijing100193 China Faculty of Pharmacy Osaka Ohtani University3-11-1 Nishikiori-kita Tondabayashi Osaka 584-8540 Japan Osaka Institute of Public Health 1-3-69 Nakamichi Higashinari Osaka 537-0025 Japan

Aeolian dust particles arising from arid and semiarid zones are known to carry microbes by air currents. The effect of wind-borne bacteria on atmospheric bacterial population at various downwind distances from the dust source regions must be clarified, but has not yet been reported. This study monitored the bacterial abundance and community composition in outdoor aerosol samples in Beijing, China, which is close to the Asian dust source regions, and compared them with the results obtained in a distant region（Osaka, Japan）.The Asian dust collected in Beijing contained（4 ± 3） × 10^4 bacterial cells/m^3, approximately 4 times higher than in Osaka. On 15 April 2015, Beijing experienced severe Asian dust events with a 1000-fold increase in bacterial abundance, relative to non-Asian dust days. Dominant bacterial phyla and classes in Asian dust collected in Beijing were Actinobacteria, Bacilli and Acidobacteria, and the bacterial community composition varied more widely than in *** bacterial community compositions differed between the Beijing and Osaka dusts, even for the same Asian dust events. These results indicated that aerosol bacterial communities nearer the dust source are more affected by eolian dust than their distant counterparts.

关键词： Aeolian dust Amplicon sequencing Asian dust Bacterial community Bioaerosols