检索结果-南通市图书馆

粪便基质金属蛋白酶9及其相关蛋白在婴儿食物过敏中的诊断价值

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

临床儿科杂志 2024年第7期42卷 619-625页

作者：高亚娟代妮妮张华李在玲北京大学第三医院儿科北京100191 北京大学第三医院流行病学研究中心北京100191

目的探索基质金属蛋白酶9(MMP9)及其相关蛋白在婴儿食物过敏(FA)中的诊断价值。方法本研究为巢式病例对照研究,连续纳入2023年4月至2023年10月疑诊FA的婴儿,收集粪便,经口服食物激发试验将入组婴儿分为FA组和非FA组。通过酶联免疫吸附... 详细信息

目的探索基质金属蛋白酶9(MMP9)及其相关蛋白在婴儿食物过敏(FA)中的诊断价值。方法本研究为巢式病例对照研究,连续纳入2023年4月至2023年10月疑诊FA的婴儿,收集粪便,经口服食物激发试验将入组婴儿分为FA组和非FA组。通过酶联免疫吸附测定法测定粪便MMP9、基质金属蛋白酶组织抑制剂1(TIMP 1)和脂质运载蛋白2(LCN 2)的浓度,通过对比粪便总蛋白浓度计算其相对含量,通过受试者工作曲线的曲线下面积(AUC)、灵敏度、特异度等指标评价目标蛋白诊断婴儿FA的准确度。二元logistic回归筛选FA预测因子。结果共纳入FA组69例及非FA组72例。粪便MMP9及TIMP 1浓度诊断FA的AUC值分别为0.82和0.78,MMP9及TIMP 1相对含量的AUC值分别增加至0.85及0.83。LCN 2诊断价值不佳。多因素logistic回归提示粪便MMP 9是FA的最佳预测指标。结论粪便MMP 9和TIMP 1是诊断婴儿FA的有用工具,可以很好的区分FA及类似疾病。

关键词：食物过敏基质金属蛋白酶9 脂质运载蛋白2 基质金属蛋白酶组织抑制剂1 婴儿

亚临界机组碳捕集系统优化及其对热力系统影响的模拟研究

在线全文

学校读者我要写书评

暂无评论

工程热物理学报 2024年第5期45卷 1255-1263页

作者：李杨王妮妮陈振华赵广强何锁盈高明高效储能及氢能利用山东省工程研究中心(山东大学能源与动力工程学院) 济南250061 山东电力工程咨询院有限公司济南250013 胜利发电厂东营257087

为降低醇胺法碳捕集系统对燃煤电厂热经济性的影响,通过ASPENPLUS软件搭建了基于速率模型的碳捕集系统,并构建了集成富液分流工艺、贫液闪蒸压缩工艺与蒸汽过热度利用的新型碳捕集系统。结果表明新型碳捕集系统在富液分流比为0.1、闪蒸... 详细信息

为降低醇胺法碳捕集系统对燃煤电厂热经济性的影响,通过ASPENPLUS软件搭建了基于速率模型的碳捕集系统,并构建了集成富液分流工艺、贫液闪蒸压缩工艺与蒸汽过热度利用的新型碳捕集系统。结果表明新型碳捕集系统在富液分流比为0.1、闪蒸压力为0.16MPa时,再生能耗最低,为3.09GJ/tCo_(2),相比常规碳捕集系统降低了20.77%,其中,蒸汽过热度的利用使得再生能耗降低了11.54%。此外,利用EBSILoN软件搭建了耦合碳捕集系统的亚临界机组热力系统,研究得到当机组负荷为127.55MW、Co_(2)捕集量为50万吨/年时,新型碳捕集机组的锅炉热负荷相比常规碳捕集机组降低了1.87%,发电煤耗降低了7.22g/kWh。可见,采取的优化措施不仅可以降低碳捕集系统的再生能耗,还大幅度改善了亚临界碳捕集机组的热经济性。

关键词：亚临界机组碳捕集系统再生能耗热力系统模拟研究

Peritoneal interposition flap reduces symptomatic lymphocele following transperitoneal robot-assisted radical prostatectomy and pelvic lymph node dissection:An updated meta-analysis

在线全文

学校读者我要写书评

暂无评论

Current Urology 2024年第3期18卷 167-176页

作者： João Henrique Sendrete de Pinho Lorrane Vieira Siqueira Riscado João Padua Manzano Faculty of Medicine of the Federal University of Juiz de Fora Minas GeraisBrazil Faculty of Medicine of the Federal University of São Paulo São PauloBrazil

Background Robot-assisted radical prostatectomy with intraoperative pelvic lymph node dissection is the criterion standard for surgical treatment of nonmetastatic intermediate-and high-risk prostate ***,this method is associated with symptomatic lymphocele(SLC),which is an important morbidity *** overcome this complication,several modifications of the technique have been developed,including the peritoneal interposition flap(PIF).We performed an updated systematic review and meta-analysis to investigate the efficacy and safety of this technique for preventing SLC and lymphocele(LC)*** and methods Searches were performed using databases and references from included studies and previous systematic *** randomized controlled trials and nonrandomized cohorts were *** outcomes were the incidence of SLC and LC formation,and safety outcomes were defined as operation time,estimated blood loss,length of hospital stay,and urinary *** assessment was performed using the Newcastle-ottawa Scale and Cochrane Collaboration's *** treatment effects were estimated using odds ratios with 95%confidence intervals(CIs)for binary *** was examined using Cochran's Q test and I2 statistics;p values25%were considered significant for *** used Mantel-Haenszel fixed-effect models in the analyses with low ***,the DerSimonian and Laird random-effects model was *** The initial search yielded 510 *** the removal of duplicate records and application of the exclusion criterion,9 studies were fully reviewed for *** randomized controlled trials and 5 retrospective cohorts met all the inclusion criteria,comprising 2261 patients,of whom 1073(47.4%)underwent *** studies reported a significant reduction in SLC in the PIF group,and 3 of the 4 studies reported LC formation yielded significant results in preventing this complication.

关键词： Robot-assisted radical prostatectomy Lymphocele Peritoneal reapproximation Peritoneal interpolated flap Meta-analysis

Physico−mathematical model of the voltage−current characteristics of light-emitting diodes with quantum wells based on the Sah−Noyce−Shockley recombination mechanism

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Semiconductors 2024年第8期45卷 25-33页

作者： Fedor I.Manyakhin Dmitry o.Varlamov Vladimir P.Krylov Lyudmila o.Morketsova Arkady A.Skvortsov Vladimir K.Nikolaev Dinamics Strength of Machines and Resisance of MaterialsMoscow Polytechnic UniversityRussia Biomedical and Electronic Means and Technologies Vladimir State UniversityRussia Computer-Aided Design and Engineering National University of Science and Technology"MISiS"Russia

Herein,a physical and mathematical model of the voltage−current characteristics of a p−n heterostructure with quantum wells(QWs)is prepared using the Sah−Noyce−Shockley(SNS)recombination mechanism to show the SNS recombination rate of the correction function of the distribution of QWs in the space charge region of diode configuration.A comparison of the model voltage−current characteristics(VCCs)with the experimental ones reveals their *** technological parameters of the structure of the VCC model are determined experimentally using a nondestructive capacitive approach for determining the impurity distribution profile in the active region of the diode structure with a profile depth resolution of up to 10Å.The correction function in the expression of the recombination rate shows the possibility of determining the derivative of the VCCs of structures with QWs with a nonideality factor of up to 4.

关键词： light-emitting diodes with quantum wells voltage−current relation nonideality factor recombination mechanism Sah−Noyce−Shockley model

Energy and blast performance of beryllium in a model thermobaric composition in comparison with aluminum and magnesium

在线全文

学校读者我要写书评

暂无评论

Defence Technology（防务技术） 2024年第6期36卷 13-19页

作者： Thomas M.Klapotke Stanisław Cudziło Waldemar A.Trzcinski Jozef Paszula Energetic Materials Research Department of ChemistryUniversity of Munich(LMU)Butenandtstrasse 5-13(D)81377MunichGermany Military University of Technology Faculty of Advanced Technologies and ChemistrySylwester Kaliski Str.200-908WarsawPoland

A direct comparison is made between the effectiveness of Al,Mg,and Be powders as additional fuels in model thermobaric compositions containing 20%fuel,20%ammonium perchlorate,and 60%RDX(1,3,5-Trinitro-1,3,5-triazacyclohexane)passivated with *** determined calorimetric measurements of the heat of detonation,along with the overpressure histories in an explosion chamber filled with nitrogen,were used to determine the quasi-static pressure(QSP)under anaerobic *** measurements were also performed in a semi-closed bunker,and all blast wave parameters generated after the detonation of 500 g charges of the tested explosives were *** calorimetry results,QSP values,and blast wave parameters(pressure amplitude,specific and total impulses)clearly indicate that Be is much more effective as an additional fuel than either Al or Mg in both anaerobic post-detonation reactions as well as the subsequent aerobic *** heat of detonation of the RDXwax/AP/Be explosive mixture is over 40%and 50%higher than that of the mixture containing aluminum and magnesium instead of beryllium,***,the TNT equivalent of the Be-containing composition due to the overpressure in the nitrogen-filled explosion chamber is 1.66,while the equivalent calculated using an air shock wave-specific impulse at a distance of 2.5 m is equal to *** high values of these parameters confirm the high reactivity of beryllium in both the anaerobic and aerobic stages of the thermobaric explosion.

关键词： Thermobaric explosives Beryllium Heat of detonation Quasi-static overpressure Blast wave parameters

可替代胎面胶用乳聚丁苯橡胶的集成橡胶SIBR实用配方研究

在线全文

学校读者我要写书评

暂无评论

石化技术 2024年第5期31卷 8-11页

作者：王妮妮中国石油化工股份有限公司北京化工研究院燕山分院橡塑新型材料合成国家工程研究中心北京102500

研究了集成橡胶SIBR2505和SIBR2535的性能特点,压缩疲劳温升低,抗湿滑性能好和滚动阻力小,可分别代替乳聚丁苯橡胶ESBR1502和ESBR1712用作轮胎胎面胶中。针对集成橡胶性能特点进行轮胎实用配方研究,配方SIBR2535-1和SIBR2505-3具有较好... 详细信息

研究了集成橡胶SIBR2505和SIBR2535的性能特点,压缩疲劳温升低,抗湿滑性能好和滚动阻力小,可分别代替乳聚丁苯橡胶ESBR1502和ESBR1712用作轮胎胎面胶中。针对集成橡胶性能特点进行轮胎实用配方研究,配方SIBR2535-1和SIBR2505-3具有较好的耐磨性和老化性能,适宜用作新能源车轮胎胎面胶;配方SIBR2535-2和SIBR2505-2具有较好的耐屈挠龟裂性能,配方SIBR2505-2和SIBR2505-3具有较好的耐刺扎性,适宜用作工程胎或农耕车胎胎面胶。配方SIBR2535-1、SIBR2535-2、SIBR2505-2和SIBR2505-3具有较高的抗湿滑性能和较低的滚动阻力,适宜用作绿色高性能轮胎胎面胶。

关键词：集成橡胶苯乙烯丁二烯异戊二烯胎面胶

Steroidal scaffold decorations in Solanum alkaloid biosynthesis

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2024年第8期17卷 1236-1254页

作者： Rosalind Lucier Mohamed o.Kamileen Yoko Nakamura Sofiia Serediuk Ranjit Barbole Jens Wurlitzer Maritta Kunert Sarah Heinicke Sarah E.o'Connor Prashant D.Sonawane Department of Natural Product Biosynthesis Max Planck Institute for Chemical Ecology07745 JenaGermany Research Group Biosynthesis and NMR Max Planck Institute for Chemical Ecology07745 JenaGermany Biochemical Sciences Division CSIR-National Chemical LaboratoryPune 411008MaharashtraIndia

Steroidal glycoalkaloids(SGAs)are specialized metabolites produced by hundreds of Solanum species,including important vegetable crops such as tomato,potato,and *** it has been known that SGAs play important roles in defense in plants and“anti-nutritional"effects(e.g.,toxicity and bitterness)to humans,many of these molecules have documented anti-cancer,anti-microbial,antiinflammatory,anti-viral,and anti-pyretic *** these,α-solasonine andα-solamargine isolated from black nightshade(Solanum nigrum)are reported to have potent anti-tumor,anti-proliferative,and anti-inflammatory ***,α-solasonine andα-solamargine,along with the core steroidal aglycone solasodine,are the most widespread SGAs produced among the Solanum ***,it is still unknown how plants synthesize these bioactive steroidal *** comparative metabolomictranscriptome-guided approach,biosynthetic logic,combinatorial expression in Nicotiana benthamiana,and functional recombinant enzyme assays,here we report the discovery of 12 enzymes from *** that converts the starting cholesterol precursorto solasodine aglycone,and the downstreamα-solasonine,α-solamargine,and malonyl-solamargine SGA *** further identified six enzymes from cultivated eggplant that catalyze the production ofα-solasonine,α-solamargine,and malonyl-solamargine SGAs from solasodine aglycone via glycosylation and atypical malonylation *** work provides the gene tool box and platform for engineering the production of high-value,steroidal bioactive molecules inheterologoushosts usingsyntheticbiology.

关键词： steroidal glycoalkaloids Solanum biosynthetic pathway α-solamargine malonyl-solamargine specialized metabolites

Alkali and Plasma-Treated Guadua angustifolia Bamboo Fibers:A Study on Reinforcement Potential for Polymeric Matrices

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Renewable Materials 2024年第8期12卷 1399-1416页

作者： Patricia Luna Juan Lizarazo-Marriaga Alvaro Mariño Facultad de Ingeniería Universidad Nacional de ColombiaBogotá11001Colombia Facultad de Ciencias Universidad Nacional de ColombiaBogotá11001Colombia

This study focuses on treating Guadua angustifolia bamboo fibers to enhance their properties for reinforcement applications in composite ***(alkali)and physical(dry etching plasma)treatments were used separately to augment compatibility of Guadua angustifolia fibers with various composite *** influence of these treatments on the fibers’performance,chemical composition,and surface morphology were *** analysis indicated that alkali treatments reduced the tensile modulus of elasticity and strength of fibers by up to 40%and 20%,respectively,whereas plasma treatments maintain the fibers’mechanical *** spectroscopy revealed significant alterations in chemical composition due to alkali treatments,while plasma-treated fibers showed minimal *** examination through Scanning Electron Microscopy(SEM)revealed post-treatment modifications in both cases;alkali treatments served as a cleanser,eliminating lignin and hemicellulose from the fiber surface,whereas plasma treatments also produce rough *** results validate the impact of the treatments on the fiber mechanical performance,which opens up possibilities for using Guadua angustifolia fibers as an alternative reinforcement in composite manufacturing.

关键词： Bamboo fibers Guadua angustifolia alkali treatment dry etching plasma treatment composite reinforcement

Tri-axial accelerometry allows to determine parental food provisioning behaviour in a marine bird

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Avian Research 2024年第3期15卷 345-351页

作者： Monserrat Del Caño Flavio Quintana Giacomo Dell’omo Agustina Gómez-Laich Instituto de Biología de organismos Marinos(IBIoMAR) CONICETBoulevard Brown 2915U9120ACDPuerto MadrynChubutArgentina ornis Italica Piazza Crati 1500199RomeItaly Departamento de Ecología Genética y Evolución(EGE)and Instituto de EcologíaGenética y Evolución de Buenos Aires(IEGEBA)CONICETFacultad de CienciasExactas y NaturalesUniversidad de Buenos AiresPabellón II Ciudad UniversitariaC1428EGACiudad Autónoma de Buenos AiresArgentina

The study of parental food provisioning is essential for understanding the breeding ecology of *** conducted the first study using accelerometry to detect food provisioning in birds,using Support Vector Machine(SVM)models to identify when adults feed chicks of three different age *** were attached to the head of adult female Imperial Shags(Leucocarbo atriceps),and various attributes derived from the acceleration signals were used to train SVM models for each chick age *** performance improved with chick age class,with SVM models achieving high overall accuracy(>88%)and highest sensitivity in older chick categories(>91%).However,precision values,especially for younger chicks,remained relatively low(between 26%and 45%).The application of a time filter based on the minimum duration of the observed food provisioning behaviours for each chick age category,improved model performance by reducing false provisioning behaviours,particularly in the model for older chicks,which showed the highest precision(72.4%).This study highlights the effectiveness of accelerometry and machine learning in studying parental food provisioning in birds,providing a rapid and accurate data collection method to complement traditional *** described methodology can be applied to any bird species that exhibits distinctive movements while feeding its offspring and has suitable characteristics for attaching an accelerometer to the body part that best captures this ***,it is hoped that the results of this study will contribute to future research on key questions in parental investment theory and reproductive strategies in birds.

关键词： Accelerometry Food provisioning Imperial shag Leucocarbo atriceps Seabird Support vector machine