检索结果-南通市图书馆

Endplate role in the degenerative disc disease:A brief review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2023年第1期11卷 17-29页

作者： tomaz velnar Lidija Gradisnik Department of Neurosurgery University Medical Centre LjubljanaLjubljana 1000Slovenia Alma Mater Europaea Maribor Maribor 2000Slovenia Institute of Biomedical Sciences University of MariborUniversity of MariborMaribor 2000Slovenia

The degenerative disease of the intervertebral disc is nowadays an important health problem,which has still not been understood and solved *** vertebral endplate is regarded as one of the vital elements in the structure of the intervertebral *** constituent cells,the chondrocytes in the endplate,may also be involved in the process of the intervertebral disc degeneration and their role is central both under physiological and pathological *** main functions include a role in homeostasis of the extracellular environment of the intervertebral disc,metabolic support and nutrition of the discal nucleus and annulus beneath and the preservation of the extracellular ***,it is understandable that the cells in the endplate have been in the centre of research from several viewpoints,such as development,degeneration and growth,reparation and remodelling,as well as treatment *** this article,we briefly review the importance of vertebral endplate,which are often overlooked,in the intervertebral disc degeneration.

关键词： Intervertebral disc Endplate Degenerative disc disease Chondrocytes Extracellular matrix

Astrocytes in the central nervous system and their functions in health and disease:A review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2023年第15期11卷 3385-3394页

作者： Lidija Gradisnik tomaz velnar Institute of Biomedical Sciences Medical Faculty MariborMaribor 2000Slovenia Department of Neurosurgery University Medical Centre LjubljanaLjubljana 1000Slovenia AMEU ECM Maribor Maribor 2000Slovenia

Astrocytes are key cells in the central nervous *** are involved in many important functions under physiological and pathological *** part of neuroglia,they have been recognised as cellular elements in their own *** name astrocyte was first proposed by Mihaly von Lenhossek in 1895 because of the finely branched processes and star-like appearance of these particular *** early as the late 19th and early 20th centuries,Ramon y Cajal and Camillo Golgi had noted that although astrocytes have stellate features,their morphology is extremely *** research has confirmed the morphological diversity of astrocytes both in vitro and in vivo and their complex,specific,and important roles in the central nervous *** this review,the functions of astrocytes and their roles are described.

关键词： Astrocytes Morphology Astrocyte functions Molecular markers

Invasive myxopapillary ependymoma of the lumbar spine: A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2019年第10期7卷 1142-1148页

作者： Tadej Strojnik Tatjana Bujas tomaz velnar Department of Neurosurgery University Medical Centre MariborMaribor 2000Slovenia Faculty of Medicine University of MariborMaribor 2000Slovenia Department of Pathology University Medical Centre MariborMaribor 2000Slovenia Department of Neurosurgery University Medical Centre LjubljanaLjubljana 1000Slovenia

BACKGROUND Myxopapillary ependymomas are rare spinal *** histologically benign,they have a tendency for local *** SUMMARY We describe a patient suffering from extra-and intradural myxopapillary ependymoma with perisacral *** was treated with subtotal resection and postoperative radiation *** treatment,he experienced slight sphincter disorders and lumboischialgic pain with no motor or sensory *** months later,a tumour regression was *** patient is still followed-up *** Lumbar myxopapillary ependymomas may present with lumbar or radicular pain,similar to more trivial *** resonance imaging(MRI)is the primary modality for *** treatment aim is to minimize both tumour and therapy-related morbidity and to involve different treatment modalities.

关键词： Myxopapillary ependymoma Spinal tumour Surgery Lumbar pain Case report

Problematics of neurosurgical service during the COVID-19 pandemic in Slovenia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2022年第34期10卷 12462-12469页

作者： Matic Munda Roman Bosnjak tomaz velnar Department of Neurosurgery University Medical Centre LjubljanaLjubljana 1000Slovenia Alma Mater Europaea AMEU-ECMMaribor 2000Slovenia

The novel coronavirus disease 2019(COVID-19)is an ongoing disease caused by severe acute respiratory syndrome coronavirus-2 that still poses an important and urgent threat to global *** Slovenia,the epidemic was declared on March 12th,2020,and since then COVID-19 has had a great impact on our health *** field of neurosurgery in particular has been experiencing difficulties in both elective and emergency *** this article,we described epidemiologic protocols and the effect that the COVID-19 pandemic had on the surgical practice and workflow of the Department of Neurosurgery at the University Medical Centre *** analyzed and compared the number of elective and emergency neurosurgical procedures in a 2-year period before and during the *** recorded a drop in cases mostly on account of elective procedures whilst emergency service remained relatively unaffected.

关键词： Neurosurgery COVID-19 Pandemic Epidemic measures Slovenia Ljubljana

Vein of Galen aneurismal malformations-clinical characteristics,treatment and presentation: Three cases report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2019年第7期7卷 855-862页

作者： Peter Spazzapan Zoran Milosevic tomaz velnar Department of Neurosurgery University Medical Centre Ljubljana Department of Radiology University Medical Centre Ljubljana

BACKGROUND The vein of Galen aneurismal malformations(VGAM) are rare arteriovenous malformations of the embryonic choroid plexus. They represent about 30% of paediatric neurovascular disorders and show diverse characteristics. The VGAM is constituted by a midline dilated venous structure that receives blood from abnormal macroscopic or microscopic arteriovenous shunting vessels. Two types of VGAM exist, the choroidal and the mural. The treatment represents a challenge with the therapeutic objective to preserve the normal brain development without creating new neurological *** SUMMARY We present three cases of VGAM in the early postnatal period and their treatment. All patents were treated with the endovascular technique, which was successful. According to our experience, the endovascular technique is a safe and efficient mode of VGAM *** The objective of treatment aims to child's normal neurological development. A proper selection of patients and a thorough diagnostic workup is of vital importance. When the endovascular treatment is performed, the primary aim is not a complete VGAM exclusion at one time, which could produce a sudden reversal of blood flow with consequent venous infarction and ischemia. The aim is therefore to occlude as much of the VGAM as needed to relieve the congestive cardiac failure, to gain time and to create the conditions for a normal maturation of the neurovascular system. With the use of endovascular techniques, which represent not only the first choice of treatment but also the only safe therapeutic modality, the natural history of VGAM and their risks may be avoided safely.

关键词： Vein of Galen Aneurismal malformation Children Treatment Case reports

Endoscopic third ventriculostomy in obstructive hydrocephalus: A case report and analysis of operative technique

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2020年第14期8卷 3039-3049页

作者： Matic Munda Peter Spazzapan Roman Bosnjak tomaz velnar Department of Neurosurgery University Medical Centre LjubljanaLjubljana 1000Slovenia AMEU-ECM Maribor Ljubljana 1000Slovenia

BACKGROUND The endoscopic third ventriculostomy(ETV)is a neuroendoscopical procedure that represents a more suitable alternative to the extracranial *** consists of fenestrating the floor of the third ventricle and thus establishing a free flow of the cerebrospinal fluid from the ventricles to the site of resorption in the subarachnoid *** offers a more physiological solution and a chance at a shunt-free life for children with *** main indication for the procedure is obstructive hydrocephalus,however,it can also be useful in patients with other forms of *** SUMMARY We present a treatment flow of a 9-year-old patient,diagnosed with an obstructive hydrocephalus due to tectal glioma that was successfully treated with an *** review the important factors influencing the success rate such as age,aetiology,shunt history,preoperative planning and visualisation of the basilar *** Even though the ETV effectively controls obstructive hydrocephalus in more than 75%of all cases,the overall success rate of the procedure varies and could be approved by the correct preoperative patient selection.

关键词： Endoscopic third ventriculostomy Neuroendoscopy Hydrocephalus Case report

Clinical infections in neurosurgical oncology:An overview

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2023年第15期11卷 3418-3433页

作者： tomaz velnar Nina Kocivnik Roman Bosnjak Department of Neurosurgery University Medical Centre LjubljanaLjubljana 1000Slovenia Alma Mater Europaea-ECM Maribor Maribor 2000Slovenia Faculty of Pharmacy University of LjubljanaLjubljana 1000Slovenia

Central nervous system(CNS)infections are urgent conditions with high morbidity and ***,viruses,parasites or fungi can cause *** infections after craniotomies are an important complication of treatment,especially in oncological patients that are already immunologically compromised due to the disease and *** consequence of CNS infections in oncological patients includes longer treatment with antibiotics,additional surgical procedures,higher treatment costs and poorer treatment ***,the management of primary pathology may be prolonged or postponed as a result of the active *** introducing new and improved protocols,tightening controls on their implementation,constantly educating the entire team involved in patient treatment and educating both patients and relatives,the incidence of infections can be reduced effectively.

关键词： Infection Central nervous system Neurosurgery Oncology

Chiari malformations in children:An overview

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2021年第4期9卷 764-773页

作者： Peter Spazzapan Roman Bosnjak Borut Prestor tomaz velnar Department of Neurosurgery University Medical Centre LjubljanaLjubljana 1000Slovenia

Chiari malformations encompass various radiological and clinical entities,sharing the herniation of the rhombencephalic structures through the foramen magnum as a common *** can be symptomatic or *** therapeutic strategies for these malformations differ on the basis of the diverse pathophysiologic processes that cause *** Chiari malformations are caused by various pathophysiologic processes,they must be recognized promptly to select the best treatment for each single case.

关键词： Chiari malformation Hydrocephalus Intracranial pressure Craniocervical junction Foramen magnum Treatment

Selective dorsal rhizotomy in cerebral palsy spasticity-a newly established operative technique in Slovenia: A case report and review of literature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2019年第10期7卷 1133-1141页

作者： tomaz velnar Peter Spazzapan Zoran Rodi Natasa Kos Roman Bosnjak Department of Neurosurgery University Medical Centre LjubljanaLjubljana 1000Slovenia AMEU-ECM Maribor Ljubljana 1000Slovenia Department of Neurophysiology University Medical Centre LjubljanaLjubljana 1000Slovenia Medical Rehabilitation Unit University Medical Centre LjubljanaLjubljana 1000Slovenia

BACKGROUND Spasticity affects a large number of children,mainly in the setting of cerebral palsy,however,only a few paediatric neurosurgeons deal with this *** is mainly due to the fact that until 1979,when Fasano has published the first series of selective dorsal rhizotomy(SDR),neurosurgeons were able to provide such children only a modest *** therapy of spasticity has made a great progress since ***,peroral drugs,intramuscular and intrathecal medicines are available,that may limit the effects of the *** addition,surgical treatment is gaining importance,appearing in the form of deep brain stimulation,peripheral nerve procedures and *** these options offer the affected children good opportunities of improving the quality of *** SUMMARY A 15-year old boy is presented that was surgically treated for spasticity as a result of cerebral *** at L1 level was performed and L1 to S1 nerve roots were isolated and divided in smaller ***,the SDR was *** We describe a patient report and surgical technique of SDR that was performed in Slovenia for the first time.

关键词： Cerebral palsy Spasticity Selective dorsal rhizotomy Operation Case report