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An Alternative Approach to the Solution of Multi-Objective Geometric Programming Problems

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Open Journal of Optimization 2017年第1期6卷 11-25页

作者： Ersoy Oz Nuran guzel Selcuk Alp Yildiz Technical University IstanbulTurkey

The aim of this study is to present an alternative approach for solving the multi-objective posynomial geometric programming problems. The proposed approach minimizes the weighted objective function comes from multi-objective geometric programming problem subject to constraints which constructed by using Kuhn-Tucker Conditions. A new nonlinear problem formed by this approach is solved iteratively. The solution of this approach gives the Pareto optimal solution for the multi-objective posynomial geometric programming problem. To demonstrate the performance of this approach, a problem which was solved with a weighted mean method by Ojha and Biswal (2010) is used. The comparison of solutions between two methods shows that similar results are obtained. In this manner, the proposed approach can be used as an alternative of weighted mean method.

关键词： Multi Objective Geometric Programming Kuhn-Tucker Conditions Taylor Series Expansion Numerical Method Weighted Mean Method

A mysterious cause of recurrent acute liver dysfunction for over a decade

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Gastroenterology Report 2022年第1期10卷 622-624页

作者： Ahmet Burak Dirim Tugba Kalayci Merve guzel Dirim Semra Demir Bilger Cavus Asli Cifcibasi Ormeci Filiz Akyuz Sabahattin Kaymakoglu Division of Nephrology Department of Internal MedicineIstanbul Faculty of MedicineIstanbul UniversityIstanbulTurkey Division of Medical Genetics Department of Internal MedicineIstanbul Faculty of MedicineIstanbul UniversityIstanbulTurkey Department of Internal Medicine Istanbul Faculty of MedicineIstanbul UniversityIstanbulTurkey Division of Allergy and Immunology Department of Internal MedicineIstanbul Faculty of MedicineIstanbul UniversityIstanbulTurkey Division of Gastroenterology Department of Internal MedicineIstanbul Faculty of MedicineIstanbul UniversityIstanbulTurkey

Introduction Acute liver failure(ALF)is an uncommon disease in pediatric *** includes infections,autoimmune diseases,inborn errors of metabolism,and *** disorders account for 25%of resolved ***,the etiology remains unknown in half of pediatric ALF[1].The recognition of molecular etiopathogenesis has been facilitated after the common use of next-generation sequencing ***,biallelic variants in neuroblastoma-amplified sequence(NBAS),Leucyl-tRNA synthetase 1(LARS1),and RAD50-interacting protein(RINT1)were identified in recurrent ALF(RALF)[2–4].

关键词： recurrent acute liver failure NBAS(neuroblastoma-amplified sequence) immunodysregulation clinical exome sequencing

Molecular dynamics simulations of the interaction of carbon nanotube and a carbon disulfide solvent

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Natural Science 2010年第8期2卷 902-910页

作者： Kholmirzo Kholmurodov guzel Aru Kenji Yasuoka 不详

An analysis of the molecular dynamics (МD) of the interaction between a carbon nanotube (CNT) and a carbon disulfide active solvent (CS2) has been carried out. The aim of the present work is to estimate the dynamical and structural behavior of the CNTCS2 system at different relative atomic concentrations and under temperature changes. The structural radial distribution functions and the dynamical configurations have been built for a CNT interacting with a CS2 solvent. A nontrivial observation for the CNTCS2 system is that the solvent carbon disulfide atoms make up a patterned (layered) formation around the carbon nanotube.

关键词： Molecular Dynamics Carbon Nanotube Carbon Disulfide Solvent

Dinutuximab beta‑targeted therapy kills beta‑cell tumors of the pancreas

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Holistic Integrative Oncology 2023年第1期2卷 38-46页

作者： Ayse Karatug Kacar Zelal Adıguzel Faculty of Science Department of BiologyIstanbul University34134-VeznecilerIstanbulTurkey School of Medicine Basic Medical SciencesDepartment of Medical BiologyKoçUniversityIstanbulTurkey

Purpose Dinutuximab beta is a monoclonal antibody used only in *** is an agent that is particularly toxic to pancreatic beta *** beta causes cytotoxicity through natural killer cells and neutrophils and shows *** this study,cytotoxicity was induced by streptozotocin without natural killer cells and *** the ability to show the effect of Dinutuximab beta without a natural killer was the first aim of this *** will be especially important in cases where the immune system is deficient,such as *** second aim of the study was to investigate the effects of Dinutuximab beta on cell viability and cell death in insulinoma under the conditions *** The effect of Dinutuximab beta in the presence of natural killer cells in vivo was created by the application of Streptozotocin to Beta-cell tumors of the pancreas in *** cell viability was determined with WST-1 *** oxygen species were measured by using dichlorofluorescein diacetate as a *** cells were marked with DAPI to indicate apoptotic markers(nuclear condensation and fragmentation)with the confocal ***2(Glucose transporter 2),IR(Insulin receptor),INS1,and INS2 expression levels were analyzed with *** The cell cytotoxicity was induced by *** cells proliferated with the administration of Dinutuximab beta *** result of Dinutuximab beta administered following Streptozotocin administration resulted in more cell death,increased ROS levels,GLUT2,Ins1,and Ins2 mRNA expression levels,and decreased IR mRNA expression ***,the cells predominantly died via apoptosis showing cytoplasmic condensation and DNA *** The lethal effect of Dinutuximab beta without a natural killer was provided by Streptozotocin in Beta cell tumors of the pancreas.

关键词： Insulinoma INS-1 cell line Dinutuximab beta Cell death Cytotoxicity

The Impact of Marine Aquaculture on the Environment;the Importance of Site Selection and Carrying Capacity

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Agricultural Sciences 2019年第3期10卷 259-266页

作者： guzel Yucel-Gier Canan Eronat Erdem Sayin Institute of Marine Sciences and Technology Dokuz Eylül UniversityHaydar Aliyev BldNo:100InciraltiIzmirTurkey

A growing increase in the world’s population and a gradual decline in poverty necessitate a search for new sources of protein in order to guarantee food security. Aquaculture has been identified as a potential sector capable of meeting the requirements for increased protein production without making excessive demands on the ecosystem. Although water makes up 70% of the earth’s surface, aquaculture cannot feasibly be practised everywhere;it requires a unique set of natural, social and economic resources to be managed in an environmentally responsible way. Finding suitable sites for aquaculture is becoming an ever increasing problem in the development of the sector as precautions need to be taken in setting up sites to ensure appropriate environmental characteristics exist and that good water quality can be maintained. Additionally, the effects of aquaculture on coastal and inland resources must be clearly determined to implement policies and regulatory frameworks to control its impact. Marine cage farming is gaining momentum, specifically in the Mediterranean and Black Sea coastal regions. For these sites to be further developed there is a need to minimize the effects on the environment and conflicts with other coastal users. To this aim the concept of allocated zones for aquaculture (AZA) is being adopted to provide specific areas for marine aquaculture to avoid environmental degradation. When choosing an (AZA) suitable site, it is vital to calculate ‘carrying capacity’ to reduce the risks and to protect the marine ecosystems. In this study the MERAMOD model was used to investigate the carrying capacity of marine fish farms. Modelling offers the possibility to simulate and predict the environmental impact of fish farms.

关键词： Environment Marine Aquaculture Site Carrying Capacity

The Effects of Complementary and Alternative Medicine on Physiological Systems： Perceptions of Health Sciences and Medical Students

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Psychology Research 2017年第6期7卷 305-317页

作者： Derya guzel Songul Doganay Deniz Oztuk Ayhan Tanyeli Sakarya University Sakarya Turkey Ataturk Universtiy Erzurum Turkey

Electron Phenomenological Spectroscopy and Its Application in Investigating Complex Substances in Chemistry, Nanotechnology and Medicine

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材料科学与工程（中英文B版） 2013年第3期3卷 183-199页

作者： Michail Yurievich Dolomatov guzel Ragipovna Mukaeva Darya Olegovna Shulyakovskaya Department of Physics Ufa State University of Economics and Service Ufa 450077 Russian Federation Department of Physical Electronics and Nanophysics Bashkir State University Ufa 450000 Russian Federation

The Distribution, Biological and Ecological Features of Typha shuttleworthii (Typhaceae) in the Vyatka-Kama Cis-Urals, Russia

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American Journal of Plant Sciences 2015年第2期6卷 283-288页

作者： Olga A. Kapitonova guzel R. Platunova Vladimir I. Kapitonov Udmurt State University Izhevsk Russia

Typha shuttleworthii is the semi-aquatic plant in the modern areal which embraces mainly the ocean districts of Europe. The eastern border of the area of this species is located in Eastern Europe on the territory of Vyatka-Kama Cis-Urals (VKCU). Almost everywhere species is considered rare and is included in the Red Data Books in many European countries. However, on the territory of Russia, T. shuttleworthii is not protected. The rarity of this species makes it necessary to study its natural populations for their protection. In the paper, we present the materials on some biological and ecological features of the Typha shuttleworthii, growing on the territory of Vyatka-Kama Cis-Urals, where the species is represented by its extreme eastern populations. This species is offered to the protection on the territory of the European part of Russia within the Republic of Tatarstan and Udmurtia.

关键词： Typha shuttleworthii Cattails Macrophyte Vyatka-Kama Cis-Urals Udmurt Republic Tatarstan Russia

The Image Conversion in Optical Echo-Holography by External Electromagnetic Standing Waves

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Optics and Photonics Journal 2016年第1期6卷 1-7页

作者： guzel I. Garnaeva Leonid A. Nefediev Alsu R. Sakhbieva Department of Educational Technologies in Physics Kazan Federal University Kazan Russia

The recording and playback of information using a reverse stimulated photon—echo hologram when exposed to the recording medium pulse of non-resonant electromagnetic standing wave was considered. It was shown that the spatial intensity distribution in stimulated echo hologram response depended on the electric field intensity of non-resonant standing wave that allowed controlling by a reproducible image.

关键词： Data Recording Playback Information A Reverse Stimulated Echo Hologram Standing Wave Control of the Reproduced Image