检索结果-南通市图书馆

维普期刊数据库博看期刊

在线全文

学校读者我要写书评

暂无评论

韩国前首富被捕身家大缩水

商业周刊（中文版） 2024年第12期 17-19页

作者： Yoolim Lee sohee Kim tom Maloney shinhye Kang 逸思(译) 不详

Kakao创始人金范洙突然被捕,引发了市场对这家互联网公司前景的质疑三年前,金范洙(Brian Kim)站到了韩国互联网行业的顶峰_成为知名企业家,为韩国5000万人口创建了主流的信息平台。如今已被拘捕的他,正准备在法庭上为自己的自由和企业... 详细信息

Kakao创始人金范洙突然被捕,引发了市场对这家互联网公司前景的质疑三年前,金范洙(Brian Kim)站到了韩国互联网行业的顶峰_成为知名企业家,为韩国5000万人口创建了主流的信息平台。如今已被拘捕的他,正准备在法庭上为自己的自由和企业帝国而战。7月23日凌晨1点刚过,这位Kakao Corp.的创始人因涉嫌在对K-pop经纪公司sM Entertainment Co.备受瞩目的收购战中操纵价格而被捕。

关键词：互联网行业信息平台金范经纪公司操纵价格韩国收购战

CD34^(+ )progenitor cells as diagnostic and therapeutic targets in Alzheimer's disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2023年第3期18卷 535-536页

作者： Daniel Romaus-sanjurjo Antía Custodia Alberto Ouro tom.s sobrino NeuroAging Group(NEURAL) Clinical Neurosciences Research Laboratory(LINC)Health Research Institute of Santiago de Compostela(IDIS)Santiago de CompostelaSpain

Alzheimer’s disease(AD)is the main neurodegenerative disease leading to dementia and cognitive impairment in the *** AD to be an epidemic,an increase from the current 50 million to more than 150 million patients is e... 详细信息

关键词： Alzheimer progenitor impairment

Abnormal Umbilical Doppler: Incidence and Neonatal Outcomes among Hypertensive Disorders in Pregnancy at KCMC: A Hospital-Based Prospective Cohort study

在线全文

学校读者我要写书评

暂无评论

Open Journal of Obstetrics and Gynecology 2024年第8期14卷 1253-1266页

作者： Yusuph Mwidibo Pendo Mlay Adnan sadiq Gosbert George Bariki Mchome Nasra Batchu Glory Mangi Raziya Gaffur Rafiki Mjema Eusebius Maro tom Kakumbi Doris Rwenyagila Gileard Masenga Patricia swai Department of Obstetrics and Gynecology Kilimanjaro Christian Medical Center (KCMC) Moshi Tanzania Department of Obstetrics and Gynecology Kilimanjaro Christian Medical University College (KCMUCo) Moshi Tanzania Department of Radiology Kilimanjaro Christian Medical Center (KCMC) Moshi Tanzania

Hypertensive disorders of pregnancy (HDP) are the most common maternal and perinatal health challenges. Globally, the incidence of HDP increased from 16.30 million to 18.08 million, with a total increase of about 10.9% from 1990 to 2019. Umbilical Doppler study in hypertensive disorders of pregnancy helps to predict neonatal outcomes and prevent neonatal and maternal morbidity and mortality. Objective: This study aims to determine the incidence of abnormal umbilical Doppler among hypertensive pregnant women, to identify the adverse neonatal outcomes associated with abnormal umbilical Doppler, and also to detect the diagnostic predictive values of umbilical Doppler to neonatal outcomes at KCMC. Material and methods: A hospital-based prospective cohort study included women with hypertensive disorders of pregnancy from the gestational age of 28 weeks and above, followed up to delivery during the study period from August 2022 to March 2023. Multivariate logistic regression analysis was used to determine the association between AUD and neonatal outcomes. Results: Out of 112 women with HDP, the incidence of abnormal umbilical Doppler was 38 (33.93%). Abnormal umbilical Doppler was associated with neonates with low birth weight aOR (95% of CI) of 4.52 (1.59 - 12.83) p = 0.005 and neonatal ICU admission 9.71 (2.90 - 32.43) p Conclusion: The incidence of abnormal umbilical Doppler is high in hypertensive disorders of pregnancy which is associated with an increase in neonatal low birth weight and neonatal ICU admissions, the sensitivity of abnormal umbilical Doppler in prediction of low birth weight and neonatal ICU admission is significant hence the routine use of umbilical Doppler assessment among hypertensive pregnant women is crucial.

关键词： Hypertensive Disorders in Pregnancy Umbilical Doppler Neonatal Outcomes KCMC

Competing-risks model for predicting the prognosis of patients with regressive melanoma based on the sEER database

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Malignancy spectrum 2024年第2期1卷 123-135页

作者： Chaodi Huang Liying Huang Jianguo Huang Xinkai Zheng Congjun Jiang Kong Ching tom UTim Wu WenHsien Ethan Huang Yunfei Gao Fangmin situ Hai Yu Liehua Deng Jun Lyu Department of Dermatology The First Affiliated Hospital of Jinan University and Jinan University Institute of DermatologyGuangzhouGuangdongChina Department of Clinical Research The First Affiliated Hospital of Jinan UniversityGuangzhouGuangdongChina Department of Dermatology Huadu District People's Hospital of GuangzhouGuangzhouGuangdongChina Department of Dermatology The First Affiliated Hospital of Bengbu Medical CollegeBengbuAnhuiChina Primax Biotech Company Hong KongChina Meng Yi Centre Limited MacaoChina GeneHope Clinic TaipeiTaiwanChina Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment Zhuhai Institute of Translational MedicineZhuhai People's Hospital Affiliated with Jinan UniversityZhuhaiGuangdongChina The Biomedical Translational Research Institute Faculty of Medical ScienceJinan UniversityGuangzhouGuangdongChina Department of Dermatology The Fifth Affiliated Hospital of Jinan UniversityHeyuanGuangdongChina Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Informatization GuangzhouGuangdongChina

Background:The relationship between the regression and prognosis of melanoma has been debated for *** competing-risk events are present,using traditional survival analysis methods may induce bias in the identified prognostic factors that affect patients with regressive ***:Data on patients diagnosed with regressive melanoma were extracted from the surveillance,Epidemiology,and End Results(sEER)database during *** incidence function and Gray's test were used for the univariate analysis,and the Cox proportional-hazards model and the Fine-Gray model were used for the multivariate ***:A total of 1442 eligible patients were diagnosed with regressive melanoma,including 529 patients who died:109 from regressive melanoma and 420 from other *** multivariate analysis using the Fine-Gray model revealed that sEER stage,surgery status,and marital status were important factors that affected the prognosis of regressive *** to the existence of competing-risk events,the Cox model may have induced biases in estimating the effect values,and the competing-risks model was more advantageous in the analysis of multipleendpoint clinical survival ***:The findings of this study may help clinicians to better understand regressive melanoma and provide reference data for clinical decisions.

关键词： competing-risks model prognosis regressive melanoma sEER Cox model

Endothelial progenitor cells as a therapeutic option in intracerebral hemorrhage

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2017年第4期12卷 558-561页

作者： Juan Pías-Peleteiro Francisco Campos José Castillo tom.s sobrino Clinical Neurosciences Research Laboratory Department of NeurologyStroke UnitUniversity Clinical HospitalUniversidade de Santiago de CompostelaHealth Research Institute of Santiago de Compostela (IDIS)

Intracerebral hemorrhage （ICH） is the most severe cerebrovascular disease, which represents a leading cause of death and disability in developed countries. However, therapeutic options are limited, so is mandatory to investigate repairing processes after stroke in order to develop new therapeutic strategies able to promote brain repair processes. Therapeutic angiogenesis and vasculogenesis hold promise to improve outcome of ICH patients. In this regard, circulating endothelial progenitor cells （EPCs） have recently been suggested to be a marker of vascular risk and endothelial function. Moreover, EPC levels have been associated with good neurological and functional outcome as well as reduced residual hematoma volume in ICH patients. Finally, experimental and clinical studies indicate that EPC might mediate endothelial cell regeneration and neovascularization. Therefore, EPC-based therapy could be an excellent therapeutic option in ICH. In this mini-review, we discuss the present status of knowledge about the possible therapeutic role of EPCs in ICH, molecular mechanisms, and the future perspectives and strategies for their use in clinical practice.

关键词： cellular therapy endothelial progenitor cells growth factors intracerebral hemorrhage neurorepair outcome

Lagoonal carbonate deposition preceding rifting-related uplift:evidence from the Bartonian-Priabonian(Eocene)of the northwestern Gulf of suez(Egypt)

在线全文

学校读者我要写书评

暂无评论

Journal of Palaeogeography 2022年第1期11卷 8-30页

作者： Emad s.sallam Dmitry A.Ruban A.J.(tom)Van Loon Department of Geology Faculty of ScienceBen ha UniversityFarid Nad a Street 15Ben ha 13518Egypt K.G.Razumovsky Moscow state University of Technologies and Management(the First Cossack University) Zemlyanoy Val Street 73Moscow 109004Russia c College of Earth science and Engineering Shandong University of Science and TechnologyQingdao 266590ShandongChina

sedimentary successions in the northwestern Gulf of suez provide important clues to the understanding of the geological evolution of NE Africa during the middle and late *** study focuses on detailed facies analyses in order to characterize the depositional environments and system tracts of the Bartonian-Priabonian succession cropping out in this ***-Priabonian carbonate deposits in five stratigraphic sections constitute,from base to top,the Gebel Hof,Observatory,sannur,Qurn,and Wadi Hof *** formations contain four local assemblage zones of larger benthic *** of litho-,bio-,and microfacies in the succession resulted in the recognition of 12 lithofacies *** lithofacies are represented by packages of lime-mudstones,wackestones,packstones,pack-to grainstones,grainstones,rudstones,boundstones and *** lithofacies have been grouped into four geneticallyrelated facies associations that represent,respectively,tidal flats/shallow subtidal,restricted-shelf/lagoonal,shoal bar,and outer-shelf lagoon/reefal depositional environments in a downslope shallow-marine inner-ramp *** vertical transitions of these facies associations,representing facies changes through time,imply fluctuations of the regional sea *** two peaks in the Bartonian correspond to well-known global eustatic sea-level rises;the pronounced Priabonian regression must be ascribed to the known global eustatic sea-level fall in combination with regional tectonic *** facies distribution suggests that the study area was located in the direct vicinity of some islands during the Bartonian-Priabonian.

关键词： Lagoonal facies sea-level fluctuations Middle Eocene Late Eocene Eastern Desert

shape design of arch dams under load uncertainties with robust optimization

在线全文

学校读者我要写书评

暂无评论

Frontiers of structural and Civil Engineering 2019年第4期13卷 852-862页

作者： Fengjie TAN tom LAHMER Institute of structural Mechanics Bauhaus-UniversitatWeimar D-99423Germany

Due to an increased need in hydro-electricity, water storage, and flood protection, it is assumed that a series of new dams will be build throughout the world. The focus of this paper is on the non-probabilistic-based design of new arch-type dams by applying means of robust design optimization (RDO). This type of optimization takes into account uncertainties in the loads and in the material properties of the structure. As classical procedures of probabilistic-based optimization under uncertainties, such as RDO and reliability-based design optimization (RBDO), are in general computationally expensive and rely on estimates of the system’s response variance, we will not follow a full-probabilistic approach but work with predefined confidence levels. This leads to a bi-level optimization program where the volume of the dam is optimized under the worst combination of the uncertain parameters. As a result, robust and reliable designs are obtained and the result is independent from any assumptions on stochastic properties of the random variables in the model. The optimization of an arch-type dam is realized here by a robust optimization method under load uncertainty, where hydraulic and thermal loads are considered. The load uncertainty is modeled as an ellipsoidal expression. Comparing with any traditional deterministic optimization method, which only concerns the minimum objective value and offers a solution candidate close to limit-states, the RDO method provides a robust solution against uncertainty. To reduce the computational cost, a ranking strategy and an approximation model are further involved to do a preliminary screening. By this means, the robust design can generate an improved arch dam structure that ensures both safety and serviceability during its lifetime.

关键词： arch dam shape optimization robust optimization load uncertainty approximation model

Application of the Engineering-Geological Conditions in Land-Use Plans in the Petrvald Region(Czech Republic)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Geologica sinica(English Edition) 2013年第1期87卷 272-285页

作者： Marian MARsCHALKO Isik YILMAZ Martin BEDNARIK Karel KUBEKA tom.s BOUCHAL Faculty of Mining and Geology Institute of Geological EngineeringVSB-Technical University of Ostrava Department of Geological Engineering Faculty of EngineeringCumhuriyet University Department of Engineering Geology Comenius UniversityFaculty of Natural Sciences Department of Building structures Faculty of Civil EngineeringVSB-Technical University of Ostrava Faculty of Mining and Geology Institute of Environmental EngineeringVSB-Technical University of Ostrava

The objective of this paper is to demonstrate necessity to inform relevant parties about engineering-geological conditions for various practical purposes, especially including appropriate land-use planning. However, the relationship between relevant geological information and the geological environment is vital for foundation engineering purposes, especially where demanding structures are involved. This information is most conveniently structured when accumulated information concerning engineering-geological zones is utilized. This necessarily includes knowledge of rock workability and also of the pre-Quaternary bedrock, and these characteristics were then related to the current built-up area and future development according to the land-use plans in a case study are from the Petrvald Region （Czech Republic）. The geological environment of area has been severely influenced by anthropogenic effects of deep black coal mining. Results of this research showed that future development should be founded on spoil banks, dumps, and settling basins. According to the land-use plan, this zone occupies 44.9% of the area of interest, and its materials predominantly emanate from mining in the Ostrava-Karvina Coal District. For future foundation structures planned there, it is imperative to consult detailed engineering-geological study. However, attention to and reliance on this necessity is not reflected in the existing land-use plan.

关键词： Geological environment land-use plan engineering-geological zones workability of rocks,GIs Petrvald Region (Czech Republic)

Following New Philanthropy by Network Ethnography:How Did the Varkey Foundation Land and Expand in Latin America?

在线全文

学校读者我要写书评

暂无评论

ECNU Review of Education 2023年第4期6卷 541-567页

作者： Iván Matovich tom.s Esper Monash University Columbia University

Purpose:New philanthropy develops new forms of policy“problem-solving”through the influx of private actors’money and *** adopts singular configurations across different policy spaces,with implications for education *** address this phenomenon by analyzing the Varkey Foundation’s(VF)“landing”and“expansion”in Latin *** is a global philanthropic organization registered in the United Kingdom in 2011 with a main hub in Argentina,where it landed in ***/Approach/Methods:We use network ethnography to examine the influence of new philanthropy on education governance as this phenomenon demands new methods to grasp the“realities”of governing beyond conventional ways and understanding policy ***:Results indicate how VF“landed”in a little pro-market space via productive uses of policy *** second phase of data collection and analysis presents further consolidation of VF in Argentina,its expansion into Latin America,and its establishment as a legitimate education policy ***/Value:This study provides new evidence and insights into how policy networks enable new philanthropy to land and consolidate within national boundaries and,later,across the region as a legitimate actor in education.

关键词： Education policy policy networks network ethnography new philanthropy Varkey Foundation