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Predicting major adverse cardiovascular events after orthotopic liver transplantation using a supervised machine learning model:A cohort study

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World Journal of Hepatology 2024年第2期16卷 193-210页

作者： Jonathan Soldera Leandro Luis Corso Matheus Machado Rech Vinícius Remus ballotin Lucas Goldmann bigarella Fernanda tomé Nathalia Moraes Rafael Sartori balbinot Santiago Rodriguez Ajacio bandeira de Mello brandão bruno Hochhegger Post Graduate Program at Acute Medicine and Gastroenterology University of South WalesCardiff CF371DLUnited Kingdom Postgraduate Program in Pathology Federal University of Health Sciences of Porto Alegre(UFCSPA)Porto Alegre 90050-170Brazil Department of Engineering Universidade de Caxias do SulCaxias do Sul 95070-560Brazil School of Medicine Universidade de Caxias do SulCaxias do Sul 95070-560Brazil Postgraduate Program in Hepatology Federal University of Health Sciences of Porto Alegre(UFCSPA)Porto Alegre 90050-170Brazil

bACKGROUND Liver transplant(LT)patients have become older and *** rate of post-LT major adverse cardiovascular events(MACE)has increased,and this in turn raises 30-d post-LT *** cardiac stress testing loses accuracy when applied to pre-LT cirrhotic *** To assess the feasibility and accuracy of a machine learning model used to predict post-LT MACE in a regional *** This retrospective cohort study involved 575 LT patients from a Southern brazilian academic *** developed a predictive model for post-LT MACE(defined as a composite outcome of stroke,new-onset heart failure,severe arrhythmia,and myocardial infarction)using the extreme gradient boosting(XGboost)machine learning *** addressed missing data(below 20%)for relevant variables using the k-nearest neighbor imputation method,calculating the mean from the ten nearest neighbors for each *** modeling dataset included 83 features,encompassing patient and laboratory data,cirrhosis complications,and pre-LT cardiac *** performance was assessed using the area under the receiver operating characteristic curve(AUROC).We also employed Shapley additive explanations(SHAP)to interpret feature *** dataset was split into training(75%)and testing(25%)*** was evaluated using the brier *** followed Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis guidelines for ***-learn and SHAP in Python 3 were used for all *** supplementary material includes code for model development and a user-friendly online MACE prediction *** Of the 537 included patients,23(4.46%)developed in-hospital MACE,with a mean age at transplantation of 52.9 *** majority,66.1%,were *** XGboost model achieved an impressive AUROC of 0.89 during the training *** model exhibited accuracy,precision,recall,and F1-score values of 0.84,0.85,0.80,and 0.79,***

关键词： Liver transplantation Major adverse cardiac events Machine learning Myocardial perfusion imaging Stress test

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A new implementation of FLEXPART with Enviro-HIRLAM meteorological input,and a case study during a heavy air pollution event

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big Earth Data 2024年第2期8卷 397-434页

作者： benjamin Foreback Alexander Mahura Petri Clusius Carlton Xavier Metin baykara Putian Zhou Tuomo Nieminen Victoria Sinclair Veli-Matti Kerminen tom V.Kokkonen Simo Hakala Diego Aliaga Risto Makkonen Alexander baklanov Roman Nuterman Men Xia Chenjie Hua Yongchun Liu Markku Kulmala Pauli Paasonen Michael boy Aerosol and Haze Laboratory Beijing Advanced Innovation Center for Soft Matter Science and EngineeringBeijing University of Chemical TechnologyBeijingChina Institute for Atmospheric and Earth System Research/Physics Faculty of ScienceUniversity of HelsinkiHelsinkiFinland Division of Nuclear Physics Department of PhysicsLund UniversityLundSweden Swedish Meteorological and Hydrological Institute(SMHI) Research DepartmentUnit of Meteorology/Environment and ClimateNorrköpingSweden Climate and Marine Sciences Department Eurasia Institute of Earth SciencesIstanbul Technical UniversityIstanbulTurkey Department of Physics Faculty of ScienceUniversity of HelsinkiHelsinkiFinland Department of Meteorology(MISU)and bolin Centre for Climate Research Stockholm UniversityStockholmSweden Climate System Research Unit Finnish Meteorological InstituteHelsinkiFinland Science and Innovation Department World Meteorological Organization(WMO)GenevaSwitzerland Niels bohr Institute University of CopenhagenCopenhagenDenmark Joint International Research Laboratory of Atmospheric and Earth System Sciences School of Atmospheric SciencesNanjing UniversityNanjingChina School of Engineering Science Lappeenranta-Lahti University of Technology(LUT)LappeenrantaFinland Atmospheric Modelling Centre Lahti Lahti University CampusLahtiFinland

We integrated Enviro-HIRLAM(Environment-High Resolution Limited Area Model)meteorological output into FLEXPART(FLEXible PARTicle dispersion model).A FLEXPART simulation requires meteorological input from a numerical weather prediction(NWP)*** publicly available version of FLEXPART can utilize either ECMWF(European Centre for Medium-range Weather Forecasts)Integrated Forecast System(IFS)forecast or reanalysis NWP data,or NCEP(*** Center for Environmental Prediction)Global Forecast System(GFS)forecast or reanalysis NWP *** primary benefits of using Enviro-HIRLAM are that it runs at a higher resolution and accounts for aerosol effects in meteorological *** compared backward trajectories gener-ated with FLEXPART using Enviro-HIRLAM(both with and without aerosol effects)to trajectories generated using NCEP GFS and ECMWF IFS meteorological inputs,for a case study of a heavy haze event which occurred in beijing,China in November *** found that results from FLEXPART were considerably different when using different meteorological *** aerosol effects were included in the NWP,there was a small but noticeable differ-ence in calculated ***,when looking at potential emission sensitivity instead of simply expressing trajectories as lines,additional information,which may have been missed when looking only at trajectories as lines,can be inferred.

关键词： Atmospheric and chemical transport modelling trajectory and particle dispersion modelling severe air pollution episode FLEXPART Enviro-HIRLAM

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高取代度阳离子淀粉基苯丙乳液的合成和应用研究

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中国造纸 2024年第9期43卷 94-102+114页

作者：刘毅王立军付文晖贾定赖亦凡 MARTIN Ekman tom Schauman 浙江科技大学环境与资源学院山西强伟纸业有限公司 Chemigate OY

以苯乙烯（St）、丙烯酸正丁酯（bA）、丙烯酸叔丁酯（tbA）为单体，H2O2-FeSO4为引发体系，高取代度阳离子淀粉（HCS）为乳化剂，开展了苯丙表面施胶剂的无皂乳液聚合。探讨了HCS的用量、分子量（以特性黏度表示）、取代度对乳液聚合... 详细信息

以苯乙烯（St）、丙烯酸正丁酯（bA）、丙烯酸叔丁酯（tbA）为单体，H2O2-FeSO4为引发体系，高取代度阳离子淀粉（HCS）为乳化剂，开展了苯丙表面施胶剂的无皂乳液聚合。探讨了HCS的用量、分子量（以特性黏度表示）、取代度对乳液聚合的影响，使用多种方法评价了乳液的理化性能与应用性能。所制备得的高取代度阳离子淀粉基苯丙乳液胶粒平均粒径小（126.2 nm）、正电性强（Zeta电位为25.8 mV）、贮存稳定性优良；将其应用在瓦楞原纸上，施胶纸张的Cobb值为21.6 g/m2，水滴接触角达121.6°，与低取代度阳离子淀粉基苯丙乳液相比，其应用效果具有明显优势。研究对其能赋予纸张更佳施胶效果的原因也提出了机理性的解释。

关键词：阳离子表面施胶剂苯丙乳液无皂聚合高取代度阳离子淀粉

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亚隔孢壳属Didymella真菌研究进展

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菌物研究 2024年第3期22卷 207-225页

作者：占浩鑫杨一帆宋婉婷 HSIANG tom 刘丽萍高洁吉林农业大学植物保护学院长春130118 圭尔夫大学环境科学学院安大略省圭尔夫N1G 2W1

亚隔孢壳属Didymella真菌可引起多种植物病害,造成作物产量损失。该属病原菌引起的植物病害症状通常表现为叶部和茎部的病斑并产生分生孢子器。亚隔孢壳属在分类学上和茎点霉属Phoma及其相关属有着密切的联系,其作为一个多系类群,同时... 详细信息

亚隔孢壳属Didymella真菌可引起多种植物病害,造成作物产量损失。该属病原菌引起的植物病害症状通常表现为叶部和茎部的病斑并产生分生孢子器。亚隔孢壳属在分类学上和茎点霉属Phoma及其相关属有着密切的联系,其作为一个多系类群,同时还包含部分未鉴定的种。文中从亚隔孢壳属的建立、分类学的发展、分子系统学研究进展、病原菌快速检测方法,以及亚隔孢壳属引起病害的综合防治研究等方面进行综述。根据已发表的84个亚隔孢壳属物种构建系统发育树表明各物种间的亲缘关系,并概述了上述亚隔孢壳属物种的分类地位变化,为系统研究亚隔孢壳属的多样性提供参考,并对今后的研究方向进行初步探讨。

关键词：亚隔孢壳属分类鉴定防治

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Diatom and Diatomite: Different Focus on Natural Media to Material Science Path

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American Journal of Analytical Chemistry 2024年第1期15卷 1-29页

作者： Secou Sall Vasiliki Papaefthimiou Thierry Dintzer Fabrice Vigneron Eric brendlé Pierre Petit tom Ferte Saliha Haddoum Sana Labidi Corinne Petit ICPEES UMR-CNRS 7515 Strasbourg University Strasbourg France Adscientis Wittelsheim France ICS CNRS UPR 22 Strasbourg France IPCMS UMR CNRS 7504 Strasbourg University Strasbourg France Ecole Nationale Polytechnique El-Harrach Algeria

bio-silica issued from diatom, a microalgae, is attracted increasing attention in material science thanks to its peculiar nanoarchitecture and related properties with versatile applications. The present work is a deep analysis on morphological and chemical properties of bio-silica issued from fossil origin (diatomaceous earth) and living one (algal paste). An optimization in purification protocol was performed to obtain multiparous bio-silica from its raw media with keeping its original shape entirely. Multiple characterization methods as scanning electronic microscopy (SEM), infrared spectroscopy, x-ray diffraction (DRX), X-ray photoelectron spectroscopy (XPS), energy dispersive X-ray spectroscopy (EDX), nitrogen adsorption and inverse gas chromatography (IGC), were used to check the purification protocol efficiency as well as to gather accurate information on morphology and chemical composition of diatom material obtained in large amount.

关键词： Diatom Diatomite bio-Silica Purification Frustule

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重塑中小学校的体验——以峪景高中为例

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当代建筑 2024年第1期 112-118页

作者：蔡羽 tom Reich(摄影) bill Timmerman(摄影) DLR Group 不详

1创新的设计理念与空间规划亚利桑那州凤凰城的峪景高中位于美国西南部平坦开阔的沙漠地带。项目启动之初,当地企业、政府官员、家长、学生等近480人参与为建设学校而开展的社区会议和设计工坊的工作中。他们连续三周对校园内每个功能... 详细信息

1创新的设计理念与空间规划亚利桑那州凤凰城的峪景高中位于美国西南部平坦开阔的沙漠地带。项目启动之初,当地企业、政府官员、家长、学生等近480人参与为建设学校而开展的社区会议和设计工坊的工作中。他们连续三周对校园内每个功能板块的配置和设计提出自己的想法。设计工坊让设计团队测试想法、微调功能,并迭代设计理念。

关键词：灵活性可适应性可持续设计

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Assessing the Efficacy of Wheat-Soybean based Intercropping System at Different Plant Densities in bambili, Cameroon

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American Journal of Plant Sciences 2024年第4期15卷 235-251页

作者： Lendzemo E. Tatah Jeazet K. Teitiogo Oben tom Tabi Tange D. Achiri Njualem D. Khumbah Chi Christopher Tamu Department of Crop Production Technology College of Technology University of Bamenda Bambili Cameroon Department of Agronomic and Applied Molecular Sciences Faculty of Agriculture and Veterinary Medicine University of Buea Buea Cameroon School of Tropical Agriculture and Natural Resource Catholic University of Cameroon Bamenda Cameroon Department of Agricultural and Environmental Engineering College of Technology University of Bamenda Bambili Cameroon

Wheat is one of the most important cereals in the world, serving as a staple for millions globally. In the wake of the geopolitical crisis between Russia and Ukraine, it has become incumbent for many countries to invest in wheat production. Improving cropping systems for wheat production is paramount. Intercropping cereals with legumes has tremendous advantages. Therefore, this study was designed to optimize wheat production by intercropping it with soybean at different densities. between March and August 2023, a randomized complete block design trial was conducted in bambili, North West of Cameroon with treatments T1 (wheat monocrop at 200,000 plants ha−1), T2 (soybean monocrop at 250,000 plants ha−1), T3 (200,000 wheat and 125,000 soybean ha−1), T4 (100,000 wheat and 250,000 soybean ha−1), T5 (200,000 wheat and 250,000 soybean ha−1) and T6 (100,000 wheat and 125,000 soybean ha−1). Results revealed that growth parameters of wheat were not significantly influenced by monocrop or intercrop. The yield of wheat was significantly higher in the monocrop than the intercrop treatments, with slight variation amongst the intercrop treatments. Soybean yield was higher in the monocrop than in the intercrop, with no variations amongst the intercrop treatments. Only the land equivalence ratio (LER) for T5 was greater than 1.0. The competitive ratio for T5 was 0.54 for wheat and 1.90 for soybean, comparatively lower than the other monocrop treatments. Intercropping wheat and soybean at 200,000:250,000 ratio is recommended.

关键词： Competitive Ration Land Equivalence Ration Intercrop Soybean Wheat

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China's Economy Continues Its Recovery

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beijing Review 2024年第17期67卷 17-17页

作者： tom Fowdy 不详

China's economy is picking up,presenting an optimistic outlook that stands in stark contrast to the predominantly negative narrative often portrayed by some Western mainstream media *** than facing decline,the Chinese economy is undergoing a *** some cases,the Western media not only exaggerate China's economic challenges but also misrepresent them.

关键词： transition. Recovery media

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Secondary rectal linitis plastica caused by prostatic adenocarcinoma-magnetic resonance imaging findings and dissemination pathways:A case report

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World Journal of Radiology 2024年第9期16卷 473-481页

作者： Andres Antonio Labra Giancarlo Schiappacasse Rolando Alfonso Cocio Jorge tomás Torres Fernando Omar González Joaquin Alberto Cristi Marcela Schultz Department of Radiology Facultad de Medicina Clínica Alemana-Universidad del DesarrolloSantiago 7650568Región MetropolitanaChile Department of Pathology Clínica Alemana de SantiagoSantiago 7650568Región MetropolitanaChile

bACKGROUND Secondary rectal linitis plastica(RLP)from prostatic adenocarcinoma is a rare and poorly understood form of metastatic spread,characterized by a desmoplastic response and concentric rectal wall infiltration with mucosal *** complicates endoscopic diagnosis and can mimic gastrointestinal *** case series underscores the critical role of magnetic resonance imaging(MRI)in identifying the distinct imaging features of RLP and highlights the importance of considering this condition in the differential diagnosis of patients with a history of prostate *** SUMMARY Three patients with secondary RLP due to prostatic adenocarcinoma presented with varied clinical *** first patient,a 76-year-old man with advanced prostate cancer,had rectal pain and *** showed diffuse prostatic invasion and significant rectal wall thickening with a characteristic"target sign"*** second,a 57-year-old asymptomatic man with elevated prostatespecific antigen levels and a history of prostate cancer exhibited rectoprostatic angle involvement and rectal wall thickening on MRI,with positron emission tomography/computed tomography PSMA confirming the prostatic origin of the metastatic *** third patient,an 80-year-old post-radical prostatectomy,presented with refractory *** revealed a neoplastic mass infiltrating the rectal *** all cases,MRI consistently showed stratified thickening,concentric signal changes,restricted diffusion,and contrast enhancement,which were essential for diagnosing secondary *** confirmed the prostatic origin of the neoplastic involvement in the *** Recognizing MRI findings of secondary RLP is essential for accurate diagnosis and management in prostate cancer patients.

关键词： Rectal linitis plastica Prostatic adenocarcinoma Signet ring cell carcinoma Metastatic spread Magnetic resonance imaging Concentric wall infiltration Case report

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FURTHER OPENING- UP IS KEY FOR CHINA’S HIGH-QUALITY DEVELOPMENT

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China Report ASEAN 2024年第1期9卷 64-64页

作者： tom Fowdy international relations analyst and a graduate of Durham and Oxford universities

The Central Economic Work Conference was held in beijing from December 11 to *** conference discussed the plans,prospects and challenges for China’s economy heading into 2024,as well as evaluating the events of this *** goes without saying that 2023 has been a challenging year for countries around the world as the global context has been *** geopolitical tensions have created a rise in uncertainties which have led to reduced growth worldwide and sent many economies into *** light of the critical factors affecting the stability of the global economy,China’s primary economic goal corresponds with the promotion and sustaining of free trade.

关键词： promotion heading OPEN

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