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The first record of a Konservat-Lagerstätten in which early post-settlement stages of fossil archaeobalanids(Cirripedia:Balanomorpha)are preserved

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Integrative Zoology 2024年第2期19卷 200-223页

作者： tomáš KoCÍ Rok GAŠPARIC John BUCKERIDGE Martina KoCoVÁ VESELSKÁ Aleš ŠoSTER Ivancická581 PragueCzech Republic Palaeontological Department Natural History MuseumNational MuseumPragueCzech Republic oertijdmuseum Bosscheweg 80Boxtel5293 WBThe Netherlands Institute for Palaeobiology and Evolution Novi TrgKamnikSlovenia Earth and oceanic Systems Group RMIT UniversityMelbourneAustralia Museums Victoria CarltonVictoriaAustralia Department of Paleobiology and Paleoecology Institute of Geology of the Czech Academy of SciencesPragueCzech Republic Institute of Geology and Palaeontology Charles UniversityPragueCzech Republic Faculty of Natural Sciences and Engineering University of LjubljanaLjubljanaSlovenia

A diverse sessile barnacle fauna from a Miocene shallow-water deposit at Dolnja Stara vas in Slovenia is *** includes the first descriptions of early post settlement juveniles of Actinobalanus sloveniensis attached to mangrove *** represent three distinct growth phases,the earliest being interpreted as being less than 24 h post settlement,the others being 1 to 2 days post *** assessment of their taphonomy is *** adult balanomorphs are attached to a variety of organic substrates,including mangrove leaves and branches,fragments of the conifers?Taxodioxylon,Carapoxylon,pine cones,molluscs,and cetacean *** barnacles include ***,Amphibalanus venustus,and Perforatus perforatus—many with opercula retained within the *** retains some of the original shell *** is the second record of barnacle–plant associations from the Central Paratethys from Kamnik and *** paleoecology and paleogeography of the site are discussed.

关键词： acorn barnacles barnacle metamorphosis epibiont paleoecology taxonomy

Effects of freeze-thaw cycles on sandstone in sunny and shady slopes

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第7期16卷 2503-2515页

作者： Dian Xiao Xiaoyan Zhao Corrado Fidelibus Roberto tomás Qiu Lu Hongwei Liu Academy of Railway Sciences Corporation Limited BeijingChina Faculty of Geosciences and Environmental Engineering Southwest Jiaotong UniversityChengduChina Department of Civil Engineering University of AlicanteAlicanteSpain Department of Innovation Engineering University of SalentoLecceItaly Department of Earth and Environmental Sciences University of Milano BicoccaMilanItaly

A growing rock engineering activity in cold regions is facing the threat of freeze-thaw(FT)weathering,especially in high mountains where the sunny-shady slope effects strongly control the difference in weathering behavior of *** this paper,an investigation of the degradation of petrophysical characteristics of sandstone specimens subjected to FT cycle tests to simulate the sunny-shady slope effects is *** this aim,non-destructive and repeatable testing techniques including weight,ultrasonic waves,and nuclear magnetic resonance methods on standard specimens were *** the sunny slope specimens,accompanied by the enlargement of small pores,100 FT cycles caused a significant decrease in P-wave velocity with an average of 23%,but a consistent rise of 0.18%in mass loss,34%in porosity,67%in pore geometrical mean radius,and a remarkable 14.5-fold increase in ***,slight changes with some abnormal trends in physical parameters of the shady slope specimens were observed during FT cycling,which can be attributed to superficial granular disaggregation and pore throat *** shocks enhance rock weathering on sunny slopes during FT cycles,while FT weathering on shady slopes is restricted to the small pores and the superficial *** two factors are primarily responsible for the differences in FT weathering intensity between sunny and shady *** conclusions derived from the interpretation of the experimental results may provide theoretical guidance for the design of slope-failure prevention measures and the selection of transportation routes in cold mountainous regions.

关键词： Sunny-shady slope Freeze and thaw Pore structure Tight rocks Talus slope Cold regions

Real-world clinical efficacy of tofacitinib in moderate-to-severe ulcerative colitis

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World Journal of Gastroenterology 2024年第34期30卷 3929-3931页

作者： Sara R Lopes Claudio Martins Madalena Teixeira David tomás Department of Gastroenterology Unidade Local de Saúde da Arrábida-Hospital de São BernardoSetúbal 2910-446Portugal

Tofacitinib is an oral small-molecule Janus kinase(JAK)inhibitor that preferentially inhibits JAK1 and *** efficacy in inducing and maintaining remission in ulcerative colitis(UC)as well as its safety profile has been demonstrated in multicenter,randomized,double-blind,placebo-controlled ***,real-world studies evaluating the effectiveness and adverse effects of tofacitinib have been conducted,affirming its clinical efficacy in moderate-to-severe UC.

关键词： Ulcerative colitis Tofacitinib Real-world studies Inflammatory bowel disease Janus kinase inhibitor

Endoscopic treatment of biliopancreatic pathology in patients with Whipple's pancreaticoduodenectomy surgical variants: Lessons learned from single-balloon enteroscopy-assisted ERCP

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Hepatobiliary & Pancreatic Diseases International 2024年第5期23卷 509-514页

作者： Rodrigo Garcés-Durán Laurent Monino Pierre H Deprez Hubert Piessevaux tom G Moreels Department of Gastroenterology and Hepatology Universitécatholique de LouvainCliniques Universitaires Saint-LucAvenue Hippocrates 101200 BrusselsBelgium

Background: Endoscopic treatment of biliopancreatic pathology is challenging due to surgically altered anatomy after Whipple's pancreaticoduodenectomy. This study aimed to evaluate the feasibility and safety of single-balloon enteroscopy-assisted endoscopic retrograde cholangiopancreatography(SBE-ERCP) to treat biliopancreatic pathology in patients with Whipple's pancreaticoduodenectomy surgical variants. Methods: We retrospectively analyzed 106 SBE-ERCP procedures in 46 patients with Whipple's variants. Technical and clinical success rates and adverse events were evaluated. Results: Biliary SBE-ERCP was performed in 34 patients and pancreatic SBE-ERCP in 17, including 5 with both indications. From a total of 106 SBE-ERCP procedures, 76 were biliary indication with technical success rate of 68/76(90%) procedures and clinical success rate of 30/34(88%) patients. Mild adverse event rate was 8/76(11%), without serious adverse events. From a total of 106 SBE-ERCP procedures, 30 were pancreatic indication with technical success rate of 24/30(80%) procedures( P = 0.194 vs. biliary SBEERCP) and clinical success rate of 11/17(65%) patients( P = 0.016 vs. biliary SBE-ERCP). Mild adverse event rate was 6/30(20%)( P = 0.194 vs. biliary SBE-ERCP), without serious adverse events. After SBE-ERCP failure, endoscopic ultrasound-guided drainage, percutaneous drainage and redo surgery were alternative therapeutic options. Conclusions: Biliopancreatic pathology after Whipple's pancreaticoduodenectomy variants can be treated using SBE-ERCP without serious adverse events. Technical and clinical success rates are high for biliary indications, whereas clinical success rate of pancreatic indications is significantly lower. SBE-ERCP can be considered as first-line treatment option in this patient group with surgically altered anatomy.

关键词： Enteroscopy Endoscopic retrograde cholangiopancreatography Pancreaticoduodenectomy Surgically altered anatomy Whipple’s procedure

Morphological and molecular description of a new species of sandfly,Sergentomyia(Neophlebotomus)ashwanii ***.(Diptera:Psychodidae)from Western Ghats,India

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Asian Pacific Journal of Tropical Medicine 2024年第5期17卷 226-234页

作者： Prasanta Saini Harish Kumar Shah Mathew Jessu Sonia T tom Anns KP Amju ICMR-Vector Control Research Centre(Field Station) KottayamKeralaIndia

objective:To report a new species of sandfly,Sergentomyia(Neophlebotomus)ashwanii ***.(Diptera:Psychodidae)from Western Ghats,***:A systematic sandfly survey was conducted in the Thrissur and Kollam districts of Kerala,India using mechanical aspirators,light and sticky traps,both indoor and outdoor habitats,for a period of one *** acid barcoding of samples was performed targeting mitochondrial cytochrome oxidase I(CoI)gene and sequence generated was subjected to phylogenetic ***:Sergentomyia(Neophlebotomus)ashwanii,a new sandfly species is recorded and described in this communication.A single row of 10-12 pointed teeth in the cibarium with 4-6 small denticles or fore-teeth are the key characteristics that is distinctive from other members of the subgenus *** CoI barcode followed by phylogenetic analysis of the nucleotide sequence confirms that specimens of the species belong to the same taxonomic group while the genetic distance(14.2%)with the congeners established it to be a different ***:The Western Ghats'being an important biodiversity hotspot and has dearth of systematic entomological surveys on *** current study tried to fill the void and also report a new sandfly species.

关键词： Sergentomyia(Neophlebotomus)ashwanii CoI barcode Western Ghats Phlebotomine sandflies

Remaking a connection:molecular players involved in post-injury synapse formation

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Neural Regeneration Research 2025年第6期20卷 1719-1720页

作者： Diogo tomé Ramiro D.Almeida iBiMED-Institute of Biomedicine Department of Medical SciencesUniversity of AveiroAveiroPortugal CNC-Center for Neuroscience and Cell Biology University of CoimbraCoimbraPortugal

Functional recovery from central nervous system(CNS)trauma depends not only on axon regeneration or compensatory sprouting of uninjured fibers but also on the ability of newly grown axons to establish functional synapses with appropriate *** several studies have successfully promoted long-distance axonal regeneration in distinct CNS injury models,none of them have resulted in a viable therapeutic approach for patient recovery.A possible reason may be the lack of new synaptogenesis for reestablishing the circuitry lost after ***,we discuss how our understanding of the mechanisms that instruct synapse formation in the injured nervous system may contribute to the design of new strategies to promote functional restoration in traumatic CNS disorders.

关键词： viable injury instru

A triangular architectural relation model among sustainability,beauty,and power

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Frontiers of Architectural Research 2024年第4期13卷 699-711页

作者： Ján Legény RobertŠpaček tomášHubinský Lucia Benkovičová Faculty of Architecture and Design Slovak University of Technology in BratislavaBratislavaSlovakia

Sustainability,beauty,and power are notions that hit our contemporary perception every ***,they have been an integral part of architecture and urban planning in various forms since the *** paper presents their fundamental descriptions,followed by an assessment of their mutual relations and impact on architecture through a triangular architectural relation model developed by the authors of the *** the theoretical thought experiment,it highlights eight boundary models along with their main characteristics,in particular,the implosion,explosion,shared-control,utilitarian,no-control,supremacy,inside-forced,and outside-forced architectural related *** models can help predict future events,explain past events,make decisions,and plan strategies,or reveal problems and propose new *** applications include determination of the causes of certain results or finding out the responsibility and mechanisms that led to *** authors are of the opinion that the mutual denominator of sustainability,beauty,and power represents ethics that should be forced in architectural education and practice.

关键词： Triangular architectural relation model Sustainability Beauty Power Thought experiment Interpretation

Single-shot 3D incoherent imaging with diffuser endoscopy

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Light(Advanced Manufacturing) 2024年第2期5卷 64-74页

作者： Julian Lich tom Glosemeyer Jürgen Czarske Robert Kuschmierz Laboratory of Measurement and Sensor System Technique TU DresdenGermany Competence Center for Biomedical Computational Laser Systems(BIoLAS) TU DresdenGermany Else Kroner Fresenius Center for Digital Health(EKFZ) TU DresdenGermany Cluster of Excellence Physics of Life TU DresdenGermany

Minimally invasive endoscopy offers a high potential for biomedical imaging ***,conventional fiberoptic endoscopes require lens systems which are not suitable for real-time 3D ***,a diffuser is utilized for passively encoding incoherent 3D objects into 2D speckle *** networks are employed for fast computational image reconstruction beyond the optical memory *** this paper,we demonstrate single-shot 3D incoherent fiber imaging with keyhole access at video *** the diffuser fiber endoscope for fluorescence imaging is promising for in vivo deep brain diagnostics with cellular resolution.

关键词： Endoscopy Diffuser Deep learning Coherent fiber bundle Multicore fiber Neural networks Fiber optics Speckle patterns Fluorescence imaging

Assessing the effect of invasive organisms on forests under information uncertainty: The case of pine wood nematode in continental Europe

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Forest Ecosystems 2024年第5期11卷 685-696页

作者： Nick Schafstall Laura Dobor Marco Baldo Andrew MLiebhold Werner Rammer Juha Honkaniemi tomás Hlásny Faculty of Forestry and Wood Sciences Czech University of Life SciencesPragueCzech Republic US Forest Service Northern Forest Research Station MorgantownUSA Ecosystem Dynamics and Forest Management Group Technical University of MunichGermany Natural Resources Institute Finland HelsinkiFinland

Forests worldwide are experiencing increasingly intense biotic disturbances;however,assessing impacts of these disturbances is challenging due to the diverse range of organisms involved and the complex interactions among *** particularly applies to invasive species,which can greatly alter ecological processes in their invaded *** we focus on the pine wood nematode(PWN,Bursaphelenchus xylophilus),an invasive pathogen that has caused extensive mortality of pines in East Asia and more recently has invaded southern *** is expected to expand its range into continental Europe with heavy impacts *** the unknown dynamics of PWN in continental Europe,we reviewed laboratory and field experiments conducted in Asia and southern Europe to parameterize the main components of PWN biology and host-pathogen interactions in the Biotic Disturbance Engine(BITE),a model designed to implement a variety of forest biotic agents,from fungi to large *** simulate dynamically changing host availability and conditions,BITE was coupled with the forest landscape model *** potential impacts of introducing PWN were assessed in a Central European forest landscape(40,928ha),likely within PWN’s reach in future decades.A parameter sensitivity analysis indicated a substantial influence of factors related to dispersal,colonization,and vegetation impact,whereas parameters related to population growth manifested a minor *** of different assumptions about biological processes resulted in differential timing and size of the main mortality wave,eliminating 40%–95%of pine trees within 100 years post-introduction,with a maximum annual carbon loss between 1.3%and 4.2%.PWN-induced tree mortality reduced the Gross Primary Productivity,increased heterotrophic respiration,and generated a distinct legacy sink effect in the recovery *** assessment has corroborated the ecological plausibility of the simulated dynamics and highlighted the need for

关键词： Biological invasions Process-based modelling Forest ecosystems Model parameters