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Incidence of Diabetes in Hepatitis C Patients in Remote Areas of Pakistan:Effect of Co-Morbidity on HCV Treatment Outcomes at Selected Secondary Care Hospitals

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Journal of Clinical and Nursing Research 2022年第4期6卷 61-68页

作者： Muhammad Khalid Khan tofeeq ur rehman Faculty of Pharmacy Gomal UniversityD.I.Khan29050Pakistan Department of Pharmacy Quaid I Azam UniversityIslamabadPakistan

The management of Hepatitis C(HCV)varies greatly due to *** of Type II Diabetes Mellitus(T2DM)and HCV infection is momentous,however,only limited studies available from remote areas of *** study aimed to assess the incidence of T2DM in Hepatitis C patients,and to measure the treatment outcomes of anti-HCV therapy in co-morbidity of diabetic patients in remote areas of Khyber Pakhtunkhwa Pakistan.A cross-sectional retrospective analysis of HCV patients(n=449)was conducted in the District Hospitals of Bannu and Lakki Marwat,*** diagnosed of HCV infection and having T2DM as comorbidity were included in the *** demographic information and laboratory parameters,such as viral load(VL),hemoglobin(Hb),alanine amino transferase(ALT),and platelet count were collected to measure treatment outcomes.T2DM was found in 33.18%of patients and significant association(p˂0.05)was found with HCV infection as a ***(SOF)and Ribavirin(RBV)therapy reduced the mean(SD)VL(×10^(3))from baseline 357.1±26.23 IU/mL to 14±2.3 IU/mL and 1.3±0.3 IU/mL at 3rd and 6th months of therapy,*** Interferon and Ribavirin(RBV)therapy reduced VL from a baseline 234.57±13.5 IU/mL to 72±7.9 IU/mL and 62±3.7 IU/mL at 3rd and 6th months of therapy,***-Interferon+Ribavirin(RBV)therapy reduced baseline VL from 337±16.27 IU/mL to 18±2.8 and 4±1 at 3^(rd) and 6^(th) month of therapy,***,Hb,ALT,and platelet count showed variations in all the studied groups.T2DM was highly prevalent and significantly associated with HCV in patients of 40 years or above and SOF+RBV combination therapy showed a better response,both in the diabetic and non-diabetic HCV patients compared to earlier the *** further confirm the finding,a study using a larger population of HCV patients with T2DM should be conducted.

关键词： Hepatitis C Type II diabetes mellitus Co-morbidity

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Risk factor profiles for gastric cancer prediction with respect to Helicobacter pylori:A study of a tertiary care hospital in Pakistan

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Artificial Intelligence in Gastroenterology 2023年第1期4卷 10-27页

作者： Shahid Aziz Simone König Muhammad Umer Tayyab Saeed Akhter Shafqat Iqbal Maryum Ibrar tofeeq ur-rehman Tanvir Ahmad Alfizah Hanafiah Rabaab Zahra Faisal Rasheed Patients Diagnostic Lab Isotope Application DivisionPakistan Institute of Nuclear Science and TechnologyIslamabad 44000Pakistan Department of Microbiology Quaid-i-Azam UniversityIslamabad 45320Pakistan Interdisciplinary Center for Clinical Research Core Unit ProteomicsUniversity of MünsterMünster 48149Germany Management Information System Division Pakistan Institute of Nuclear Science and TechnologyIslamabad 44000Pakistan Centre for Liver and Digestive Diseases Holy Family HospitalRawalpindi 46300Pakistan Pakistan Scientific and Technological Information Centre Quaid-i-Azam UniversityIslamabad 45320Pakistan Department of Pharmacy Quaid-i-Azam UniversityIslamabad 45320Pakistan Faculty of Medicine Department of Medical Microbiology and ImmunologyUniversiti Kebangsan MalaysiaCherasKuala Lumpur 56000Malaysia

BACKGROUND Gastric cancer(GC)is the fourth leading cause of cancer-related deaths *** relies on histopathology and the number of endoscopies is *** pylori(***)infection is a major risk *** To develop an in-silico GC prediction model to reduce the number of diagnostic surgical *** meta-data of patients with gastroduodenal symptoms,risk factors associated with GC,and *** infection status from Holy Family Hospital Rawalpindi,Pakistan,were used with machine *** A cohort of 341 patients was divided into three groups[normal gastric mucosa(NGM),gastroduodenal diseases(GDD),and GC].Information associated with socioeconomic and demographic conditions and GC risk factors was collected using a *** infection status was determined based on urea breath *** association of these factors and histopathological grades was assessed statistically.K-Nearest Neighbors and Random Forest(RF)machine learning models were *** This study reported an overall frequency of 64.2%(219/341)of *** infection among enrolled *** was higher in GC(74.2%,23/31)as compared to NGM and GDD and higher in males(54.3%,119/219)as compared to *** abdominal pain(72.4%,247/341)was observed than other clinical symptoms including vomiting,bloating,acid reflux and *** majority of the GC patients experienced symptoms of vomiting(91%,20/22)with abdominal pain(100%,22/22).The multinomial logistic regression model was statistically significant and correctly classified 80%of the GDD/GC ***,income level,vomiting,bloating and medication had significant association with GDD and GC.A dynamic RF GC-predictive model was developed,which achieved>80%test *** GC risk factors were incorporated into a computer model to predict the likelihood of developing GC with high sensitivity and *** model is dynamic and will be further improved and validated by including n

关键词： Gastric cancer Gastritis Machine learning Prediction model Helicobacter pylori

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Comprehensive Review and Analysis on Facial Emotion Recognition:Performance Insights into Deep and Traditional Learning with Current Updates and Challenges

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Computers, Materials & Continua 2025年第1期82卷 41-72页

作者： Amjad rehman Muhammad Mujahid Alex Elyassih Bayan AlGhofaily Saeed Ali Omer Bahaj Artificial Intelligence&Data Analytics Lab College of Computer&Information SciencesPrince Sultan UniversityRiyadh11586Saudi Arabia MIS Department College of Business Administration Prince Sattam Bin Abdulaziz UniversityAlKharj11942Saudi Arabia

In computer vision and artificial intelligence,automatic facial expression-based emotion identification of humans has become a popular research and industry *** demonstrations and applications in several fields,including computer games,smart homes,expression analysis,gesture recognition,surveillance films,depression therapy,patientmonitoring,anxiety,and others,have brought attention to its significant academic and commercial *** study emphasizes research that has only employed facial images for face expression recognition(FER),because facial expressions are a basic way that people communicate meaning to each *** immense achievement of deep learning has resulted in a growing use of its much architecture to enhance *** review is on machine learning,deep learning,and hybrid methods’use of preprocessing,augmentation techniques,and feature extraction for temporal properties of successive frames of *** following section gives a brief summary of assessment criteria that are accessible to the public and then compares them with benchmark results the most trustworthy way to assess FER-related research topics *** this review,a brief synopsis of the subject matter may be beneficial for novices in the field of FER as well as seasoned scholars seeking fruitful avenues for further *** information conveys fundamental knowledge and provides a comprehensive understanding of the most recent state-of-the-art research.

关键词： Face emotion recognition deep learning hybrid learning CK+ facial images machine learning technological development

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The Kadomtsev-Petviashvili equation for dust ion-acoustic solitons in pair-ion plasmas

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Chinese Physics B 2013年第3期22卷 366-371页

作者： Hafeez ur-rehman Theoretical Plasma Physics Division PINSTECHP.O.NiloreIslamabadPakistan Department of Physics and Applied Mathematics PIEASP.O.NiloreIslamabadPakistan

Using the reductive perturbation method,we have derived the Kadomtsev-Petviashvili（KP） equation to study the nonlinear properties of electrostatic collisionless dust ion-acoustic solitons in pair-ion（p-i） *** have chosen the fluid model for the positive ions,the negative ions,and a fraction of static charged（both positively and negatively） dust *** solutions of these dust ion-acoustic solitons are plotted and their characteristics are *** is found that only the amplitudes of the electrostatic dust ion-acoustic solitons vary when the dust is introduced in the pair-ion *** is also noticed that the amplitude and the width of these solitons both vary when the thermal energy of the positive or negative ions is *** is shown that potential hump structures are formed when the temperature of the negative ions is higher than that of the positive ions,and potential dip structures are observed when the temperature of the positive ions supersedes that of the negative *** the pair-ion plasma mimics the electron-positron plasma,thus our results might be helpful in understanding the nonlinear dust ion acoustic solitary waves in super dense astronomical bodies.

关键词： charged and static dust particles pair-ion plasma soliton

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Electrostatic Dust Acoustic Solitons in Pair-Ion-Electron Plasmas

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Chinese Physics Letters 2012年第6期29卷 207-210页

作者： Hafeez ur rehman Theoretical Plasma Physics Division Pakistan Institute of Nuclear Science and Technology(PINSTECH)P.O.NiloreIslamabadPakistan Department of Physics and Applied Mathematics Pakistan Institute of Engineering and Applied Sciences(PIEAS)P.O.NiloreIslamabadPakistan

Using the reductive perturbation method,a Korteweg-de Vries (KdV) equation is derived to study the nonlinear properties of electrostatic collisionless dust acoustic solitons in pair-ion-electron (p-i-e) *** Buid model is chosen for positive ions,negative ions,and the fraction of electrons and charged (both positive and negative)dynamic dust *** is realized that electrostatic hump structures can be found when the dust particles are positively charged,and electrostatic dip structures can be detected for negatively charged dust *** solutions for these dust acoustic solitous are plotted and their characteristics are *** is found that the amplitude and width of the electrostatic dust acoustic solitons increase when the density of the dust particles and/or the temperature of the negative ions increases,and that the amplitude and width of these solitons decrease when the temperature of the positive ions *** pair-ion plasmas mimic electron-positron plasmas,our results might be helpful in understanding the nonlinear dust acoustic solitary waves in super dense astronomical bodies like neutron stars.

关键词： particles electrostatic solitons

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Quantum spin Hall and quantum valley Hall effects in trilayer graphene and their topological structures

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Chinese Physics B 2017年第12期26卷 481-490页

作者： Majeed ur rehman A A Abid ICQD Hefei National Laboratory for Physical Sciences at Microscale Department of Physics University of Science and Technology of China Hefei 230026 China Key Laboratory of Geospace Environment(Chinese Academy of Sciences) Department of Geophysics and Planetary Science University of Science and Technology of China Hefei 230026 China

The present study pertains to the trilayer graphene in the presence of spin orbit coupling to probe the quantum spin/valley Hall effect. The spin Chern-number Cs for energy-bands of trilayer graphene having the essence of intrinsic spin-orbit coupling is analytically calculated. We find that for each valley and spin, Cs is three times larger in trilayer graphene as compared to single layer graphene. Since the spin Chern-number corresponds to the number of edge states, consequently the trilayer graphene has edge states, three times more in comparison to single layer graphene. We also study the trilayer graphene in the presence of both electric-field and intrinsic spin-orbit coupling and investigate that the trilayer graphene goes through a phase transition from a quantum spin Hall state to a quantum valley Hall state when the strength of the electric field exceeds the intrinsic spin coupling strength. The robustness of the associated topological bulk-state of the trilayer graphene is evaluated by adding various perturbations such as Rashba spin-orbit （RSO） interaction αR, and exchange-magnetization M. In addition, we consider a theoretical model, where only one of the outer layers in trilayer graphene has the essence of intrinsic spin-orbit coupling, while the other two layers have zero intrinsic spin-orbit coupling. Although the first Chern number is non-zero for individual valleys of trilayer graphene in this model, however, we find that the system cannot be regarded as a topological insulator because the system as a whole is not gaped.

关键词： trilayer graphene quantum spin Hall effect topological insulator quantum phase transition

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Gender disparities and woman-specific trends in Barrett’s esophagus in the United States:An 11-year nationwide populationbased study

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World Journal of Methodology 2025年第1期15卷 60-71页

作者： Karina Fatakhova Faisal Inayat Hassam Ali Pratik Patel Attiq ur rehman Arslan Afzal Muhammad Sarfraz Shiza Sarfraz Gul Nawaz Ahtshamullah Chaudhry Rubaid Dhillon Arthur Dilibe Benjamin Glazebnik Lindsey Jones Emily Glazer Division of Gastroenterology and Hepatology Mather Hospital and Zucker School of Medicine at Hofstra UniversityPort JeffersonNY 11777United States Department of Internal Medicine Allama Iqbal Medical CollegeLahorePunjab 54550Pakistan Division of Gastroenterology and Hepatology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Division of Gastroenterology and Hepatology Geisinger Wyoming Valley Medical CenterWilkes-BarrePA 18711United States Department of Internal Medicine East Carolina University Brody School of MedicineGreenvilleNC 27834United States Department of Internal Medicine St.Dominic's HospitalJacksonMS 39216United States Department of Gastroenterology Hepatologyand NutritionCleveland Clinic FoundationClevelandOH 44195United States Department of Internal Medicine Mather Hospital and Hofstra University ZuckerSchool of MedicinePort JeffersonNY 11777United States

BACKGROUND Barrett's esophagus(BE)is a known premalignant precursor to esophageal adenocarcinoma(EAC).The prevalence rates continue to rise in the United States,but many patients who are at risk of EAC are not *** practice guidelines include male gender as a predisposing factor for BE and *** population-based clinical evidence regarding female gender remains *** To study comparative trends of gender disparities in patients with BE in the United *** A nationwide retrospective study was conducted using the 2009-2019 National Inpatient Sample(NIS)*** with a primary or secondary diagnosis code of BE were *** major outcome of interest was determining the gender disparities in patients with *** analysis for respective outcomes for females was also reported to ascertain any time-based *** We identified 1204190 patients with BE for the study *** the included patients,717439(59.6%)were men and 486751(40.4%)were *** mean age was higher in women than in men(67.1±0.4 vs 66.6±0.3 years,P<0.001).The rate of BE per 100000 total NIS hospitalizations for males increased from 144.6 in 2009 to 213.4 in 2019(P<0.001).The rate for females increased from 96.8 in 2009 to 148.7 in 2019(P<0.001).There was a higher frequency of obesity among women compared to men(17.4%vs 12.6%,P<0.001).Obesity prevalence among females increased from 12.3%in 2009 to 21.9%in 2019(P<0.001).A lower prevalence of smoking was noted in women than in men(20.8%vs 35.7%,P<0.001).However,trend analysis showed an increasing prevalence of smoking among women,from 12.9%in 2009 to 30.7%in 2019(P<0.001).Additionally,there was a lower prevalence of alcohol abuse,Helicobacter pylori(***),and diabetes mellitus among females than males(P<0.001).Trend analysis showed an increasing prevalence of alcohol use disorder and a decreasing prevalence of *** and diabetes mellitus among women(P<0.001).CONCLUSION The prevalence of BE among

关键词： Barrett’s esophagus Gender disparity Epidemiological trends Esophageal adenocarcinoma Screening endoscopy Female gender Risk factors

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Investigation of ZrO2 nanoparticles concentration and processing time effect on the localized PEO coatings formed on AZ91 alloy

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Journal of Magnesium and Alloys 2019年第4期7卷 555-565页

作者： Zeeshan ur rehman Dongjin Choi School of Materials Science and Engineering Hongik UniversitySejongRepublic of Korea

AZ91 Mg alloy was treated through a new localized PEO(Plasma Electrolytic Oxidation)coating approach,using electrolyte solutions with varying ZrO2 nanoparticles concentration(2-8 g/L)and processing *** increase in the ZrO2 concentration,several microstructural changes were observed including;formation of cluster-type structure,damage to the inner layers(∼30 min)and sealing of *** analysis of the final coatings was carried out using potentiodynamic polarization,electrochemical impedance spectroscopy and post-corrosion *** was explored that highest corrosion resistance(Rp∼81.17 kΩcm^2)of the coatings was obtained for ZrO2∼2 g/***,higher concentration of the ZrO2 nanoparticles caused weak crystalline coating structure,due to unstable and lower intensity discharges,thus failed to offer high corrosion resistance performance.

关键词： Magnesium alloy PEO coating ZrO2 Corrosion Nanoparticles addition

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ULAM-HYERS-RASSIAS STABILITY AND EXISTENCE OF SOLUTIONS TO NONLINEAR FRACTIONAL DIFFERENCE EQUATIONS WITH MULTIPOINT SUMMATION BOUNDARY CONDITION

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Acta Mathematica Scientia 2020年第2期40卷 589-602页

作者： Syed Sabyel HAIDER Mujeeb ur rehman School of Natural Sciences National University of Sciences and TechnologyH-12 Islamabad44000Pakistan

The purpose of this study is to acquire some conditions that reveal existence and stability for solutions to a class of difference equations with non-integer orderμ∈(1,2].The required conditions are obtained by applying the technique of contraction principle for uniqueness and Schauder’s fixed point theorem for ***,we establish some conditions under which the solution of the considered class of difference equations is generalized Ulam-Hyers-Rassias *** for the illustration of results is given.

关键词： Fractional difference equation Green's function existence and uniqueness Ulam-Hyers-Rassias stability summation boundary condition

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Topology and ferroelectricity in group-V monolayers

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Chinese Physics B 2020年第5期29卷 1-12页

作者： Mutee ur rehman Chenqiang Hua Yunhao Lu State Key Laboratory of Silicon Materials School of Materials Science and EngineeringZhejiang UniversityHangzhou 310027China Zhejiang Province Key Laboratory of Quantum Technology and Device Department of PhysicsZhejiang UniversityHangzhou 310027China

The group-V monolayers(MLs)have been studied intensively after the experimental fabrication of two-dimensional(2D)graphene and black *** observation of novel quantum phenomena,such as quantum spin Hall effect and ferroelectricity in group-V elemental layers,has attracted tremendous attention because of the novel physics and promising applications for nanoelectronics in the 2D *** this review,we comprehensively review recent research progress in engineering of topology and ferroelectricity,and several effective methods to control the quantum phase transition are *** then introduce the coupling between topological orders and ferroelectric *** research directions and outlooks are discussed at the end of the *** is expected that the comprehensive overview of topology and ferroelectricity in 2D group-V materials can provide guidelines for researchers in the area and inspire further explorations of interplay between multiple quantum phenomena in low-dimensional systems.

关键词： topology ferroelectricity two-dimensional material group-V element

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