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Journal of Molecular Cell Biology 2022年第1期14卷 60-61页

作者： Xiaohua Duan Hui Wang David D.Ho Robert E.Schwartz todd Evans Shuibing Chen Department of Surgery Weill Cornell Medicine1300 York Ave.New YorkNY 10065USA State Key Laboratory of Oncogenes and Related Genes Center for Single-Cell OmicsSchool of Public HealthShanghai Jiao Tong University School of MedicineShanghai 200025China Aaron Diamond AIDS Research Center Columbia University Vagelos College of Physicians and SurgeonsNew YorkNY 10032USA Division of Gastroenterology and Hepatology Department of MedicineWeill Cornell Medicine1300 York Ave.New YorkNY 10065USA Department of physiology Biophysics and Systems BiologyWeill Cornell Medicine1300 York Ave.New YorkNY 10065USA

Coronavirus disease 2019(COVID-19)has been an ongoing public health crisis since the end of 2019;besides vaccine development,there have been major research efforts focused on developing antiviral *** was the first US Food and Drug Administration(FDA)-approved antiviral drug for ***,the FDA granted emergency use authorization(EUA)for three monoclonal antibody treatments,including sotrovimab or a combination of casirivimab and imdevimab,or bamlanivimab and etesevimab,each of which targets the coronavirus spike protein to block viral *** recently,Britain granted conditional authorization for the ribonucleoside analog molnupiravir,developed by Merck as a viral replication *** protease inhibitor pF-07321332 developed by pfizer and boosted by ritonavir showed promising results in a phase III clinical trial,reducing the risk of hospitalization or death by 89%compared with placebo.

关键词： pfizer Merck vaccine

parallel DNA Constrained by“CC^+Clamps”

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Chemical Research in Chinese Universities 1999年第2期15卷 42-47页

作者： LIU Ke-liang H.todd Miles Frank B.Howard Joe Frazier V.Sasisekharan Laboratory of Molecular Biology NIDDKNational Institutes of HealthBethesdaMaryland20892USA

ＩｎｔｒｏｄｕｃｔｉｏｎＩｎａｄｄｉｔｉｏｎｔｏｔｈｅｆａｍｉｌｉａｒａｎｔｉｐａｒａｌｅｌＷａｔｓｏｎ－Ｃｒｉｃｋｄｕｐｌｅｘｅｓ，ｉｔｉｓａｌｓｏｐｏｓｓｉｂｌｅｔｏｆｏｒｍｐａｒａｌｅｌＤＮＡｈｅｔｅｒｏｄｕｐ... 详细信息

ＩｎｔｒｏｄｕｃｔｉｏｎＩｎａｄｄｉｔｉｏｎｔｏｔｈｅｆａｍｉｌｉａｒａｎｔｉｐａｒａｌｅｌＷａｔｓｏｎ－Ｃｒｉｃｋｄｕｐｌｅｘｅｓ，ｉｔｉｓａｌｓｏｐｏｓｓｉｂｌｅｔｏｆｏｒｍｐａｒａｌｅｌＤＮＡｈｅｔｅｒｏｄｕｐｌｅｘｅｓｗｉｔｈｒｅｖｅｒｓｅＷ...

关键词： parallel DNA helices Reverse Watson-Crick pairing CC+ base pair Oligonucleotide helices, Reverse WatsonCrick pairing, CC+ base pair, Oligonucleotide

Optimizing methyl-eugenol aromatherapy to maximize posttreatment effects to enhance mating competitiveness of male Bactrocera carambolae （Diptera： Tephritidae）

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Insect Science 2015年第5期22卷 661-669页

作者： Ihsan ul Haq Marc J.B. Vreysen Carlos Caceres todd E. Shelly Jorge Hendrichs Insect pest Control Laboratory Joint FAOIIAEA Division of Nuclear Techniques in Food and Agriculture Seibersdorf Austria National Agricultural Research Centre Park Road Islamabad Pakistan USDAIApHIS 41-650 Ahiki Street Waimanalo HI 96795 USA and Insect pest Control Section Joint FAOIIAEA Division of Nuclear Techniques in Food and Agriculture Vienna Austria

Methyl-eugenol （ME）（1,2-dimethoxy-4-（2-propenyl）benzene）, a natural phy- tochemical, did enhance male Bactrocera carambolae Drew ＆ Hancock （Diptera： Tephri- tidae） mating competitiveness 3 d after ingestion. Enhanced male mating competitiveness can significantly increase the effectiveness of the sterile insect technique （SIT）. ME appli- cation to mass reared sterile flies by feeding is infeasible. ME application by aromatherapy however, would be a very practical way of ME application in fly emergence and release facilities. This approach was shown to enhance mating competitiveness ofB. carambolae 3 d posttreatment （DpT）. Despite this added benefit, every additional day of delaying re- lease will reduce sterile fly quality and will add cost to SIT application. The present study was planned to assess the effects of ME-aromatherapy on male B. carambolae mating competitiveness 1DpT and 2DpT. ME aromatherapy 1DpT or 2DpT did enhance mating competitiveness of B. carambolae males whereas ME feeding 1DpT and 2DpT did not. Male mating competitiveness was enhanced by the ME aromatherapy irrespective if they received 1DpT, 2DpT or 3DpT. ME aromatherapy, being a viable approach for its applica- tion, did enhance mating competitiveness of male B. carambolae 1 d posttreatrnent as ME feeding did 3 d after ingestion.

关键词： Bactrocera carambolae mating competitiveness ME aromatherapy methyl-eugenol ME feeding posttreatment effect SIT

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海洋快速变暖科学家利用AI拯救珊瑚

商业周刊(中文版) 2023年第21期 52-53页

作者： todd Woody 程玺(译) 不详

科学家正在研究一种独特的加快珊瑚修复的方案旧金山一座码头的一栋楼里塞满了机器人、3D打印机等机械设备。这实在不像一个有望拯救珊瑚礁免受气候变化影响的地方。但过去4年来,一名澳大利亚珊瑚科学家一直在与工业设计软件公司Autodes... 详细信息

科学家正在研究一种独特的加快珊瑚修复的方案旧金山一座码头的一栋楼里塞满了机器人、3D打印机等机械设备。这实在不像一个有望拯救珊瑚礁免受气候变化影响的地方。但过去4年来,一名澳大利亚珊瑚科学家一直在与工业设计软件公司Autodesk Inc.的技术人员合作,开发能自动修复珊瑚的人工智能机器人。

关键词：自动修复 Autodesk 机器人气候变化影响机械设备技术人员 AI 珊瑚礁

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电动拖车来袭传统房车面临挑战

商业周刊(中文版) 2023年第20期 32-34页

作者： todd Woody 程玺(译) 不详

2015年,特斯拉推出ModelX时,全球第一辆电动SUV拖着一辆Airstream旅行拖车登上舞台。这似乎无意中埋下了一个伏笔,如今,价值300亿美元的美国休闲车市场也开始享受特斯拉的待遇。由这家电动汽车公司的前雇员组建的两家加州初创公司开发... 详细信息

2015年,特斯拉推出ModelX时,全球第一辆电动SUV拖着一辆Airstream旅行拖车登上舞台。这似乎无意中埋下了一个伏笔,如今,价值300亿美元的美国休闲车市场也开始享受特斯拉的待遇。由这家电动汽车公司的前雇员组建的两家加州初创公司开发出了首批可自推进的、电池和太阳能供电的旅行拖车,将于2024年底上市。

关键词：初创公司太阳能供电特斯拉休闲车电动汽车面临挑战拖车

Mathematical Methods and Algorithms for Signal processing

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On ＂not knowing what to say＂ in the Tragic Face of Another： Radical phenomenology as Abysmal Consolation

2000年

作者： todd K. Moon Wynn C. Stirling

来源：畅想之星图书光盘版（南... 评论

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Journal of philosophy Study 2011年第2期1卷 130-138页

作者： todd DuBose The Chicago School of professional psychology

These reflections address the disturbing phenomenon of "not knowing what to say" to someone who has experienced the immediacy of a traumatic event and who, nevertheless, seeks a word of consolation from us to ease the suffering. The author addresses the inadequacy of consolation as mere verbiage, and then brings to mind an expanded understanding of discourse-as-comportment to offer the possibility of deep consolation for the suffering other in the groundlessness of the tragic situation, which the author calls "abysmal consolation". In the realization that discourse is also the embodied consolation of being-with the suffering other in a shattered lifeworld, both sufferer and carer of souling are freed up to meet each other in a place that was heretofore presumed to be an alienated and speechless place.

关键词：悲剧生活世界创伤性地址痛苦话语

Simultaneous removal of ammonia and N-nitrosamine precursors from high ammonia water by zeolite and powdered activated carbon

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Journal of Environmental Sciences 2018年第2期30卷 82-91页

作者： Runmiao Xue Ariel Donovan Haiting Zhang Yinfa Ma Craig Adams John Yang Bin Hua Enos Inniss todd Eichholz Honglan Shi Department of Chemistry and Environmental Research Center Missouri University of Science and Technology RoIIa MO 65409 USA Center for Single Nanoparticle Single Cell and Single Molecule Monitoring (CS3M) Missouri University of Science and Technology RollaMO 6S409 USA Department of Civil Engineering Saint Louis University St. Louis MO 63103 USA Department of Agriculture and Environmental Sciences Lincoln University of Missouri Jefferson City MO 65101 USA Department of Civil & Environmental Engineering University of Missouri-Columbia Columbia MO 65211 USA Missouri Department of Natural Resources Jefferson City MO 65102 USA

When adding sufficient chlorine to achieve breakpoint chlorination to source water containing high concentration of ammonia during drinking water treatment, high concentrations of disinfection by-products（DBps） may form. If N-nitrosamine precursors are present, highly toxic N-nitrosamines, primarily N-nitrosodimethylamine（NDMA）, may also form. Removing their precursors before disinfection should be a more effective way to minimize these DBps formation. In this study, zeolites and activated carbon were examined for ammonia and N-nitrosamine precursor removal when incorporated into drinking water treatment *** test results indicate that Mordenite zeolite can remove ammonia and five of seven N-nitrosamine precursors efficiently by single step adsorption test. The practical applicability was evaluated by simulation of typical drinking water treatment processes using six-gang stirring system. The Mordenite zeolite was applied at the steps of lime softening, alum coagulation, and alum coagulation with powdered activated carbon（pAC） sorption. While the lime softening process resulted in poor zeolite performance, alum coagulation did not impact ammonia and N-nitrosamine precursor removal. During alum coagulation, more than67% ammonia and 70%–100% N-nitrosamine precursors were removed by Mordenite zeolite（except 3-（dimethylaminomethyl）indole（DMAI） and 4-dimethylaminoantipyrine（DMAp））. pAC effectively removed DMAI and DMAp when added during alum coagulation. A combination of the zeolite and pAC selected efficiently removed ammonia and all tested seven N-nitrosamine precursors（dimethylamine（DMA）, ethylmethylamine（EMA）, diethylamine（DEA）, dipropylamine（DpA）, trimethylamine（TMA）, DMAp, and DMAI） during the alum coagulation process.

关键词： Disinfection by-products Drinking water treatment Ammonia removal by zeolite N-nitrosodimethylamine(NDMA) N-nitrosamines N-nitrosamine precursor removal by zeolite and powdered activated carbon

Admussen, Nick. Recite and Refuse： Contemporary Chinese prose poetry.

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Frontiers of Literary Studies in China-Selected publications from Chinese Universities 2018年第1期12卷 140-144页

作者： todd Foley New York University

While modern Chinese literature in English translation may be enjoying increased visibility in recent years, prose poetry （Sanwen shi 散文诗） has hardly become a familiar genre （even for those of us in the field of Chinese literature, if I may take myself as an example）. Realizing, furthermore, that Recite and Refuse focuses primarily on contemporary prose poetry and is therefore only tangentially concerned with Lu Xun＇s well-known masterpiece Wild Grass.

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Trade-off between cellular immunity and life span in meal- worm beetles Tenebrio molitor

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Current Zoology 2013年第3期59卷 340-346页

作者： Indrikis KRAMS Janina DAUKSTE Inese KIVLENIECE Ants KAASIK Tatjana KRAMA todd M. FREEBERG Markus J. RANTALA Institute of Systematic Biology University of Daugavpils LV-5401 Daugavpils Latvia Institute of Ecology and Earth Sciences University of Tartu 51014 Tartu Estonia Department of Biology University of Turku FIN-20024 Turku Finland Department of psychology University of Tennessee TN 37996 Knoxville USA

Encapsulation is a nonspecific, cellular response through which insects defend themselves against multicellular pathogens. During this immune reaction, haemocytes recognize an object as foreign and cause other haemocytes to aggregate and form a capsule around the object, often consisting of melanized cells. The process of melanisation is accompanied by the formation of potentially toxic reactive oxygen species, which can kill not only pathogens but also host cells. In this study we tested whether the encapsulation response is costly in mealworm beetlesTenebrio molitor. We found a negative relationship between the duration of implantation via a nylon monofilament and remaining life span. We also found a negative relationship between the strength of immune response and remaining life span, suggesting that cellular immunity is costly inT. molitor, and that there is a trade-off between immune response and remaining life span. However, this relationship disappeared at 31-32 hours of implantation at 25 ± 2°C. As the disappearance of a relationship between duration of implantation and lifespan coincided with the highest values of encapsulation response, we concluded that the beetles stopped investment in the production of melanotic cells, as the implant, a synthetic parasite, was fully isolated from the host’s tissues.

关键词：剩余寿命细胞免疫黄粉虫甲虫权衡蠕虫膳食免疫反应