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Load and velocity boundaries of oil-based superlubricity using 1,3-diketone

Friction 2023年第5期11卷 704-715页

作者： Yuyang YUAN tobias AMANN Yuwen XU Yan ZHANG Jingfu CHEN Chenqing YUAN Ke LI School of Transportation and Logistics Engineering Wuhan University of TechnologyWuhan 430063China Reliability Engineering Institute National Engineering Research Center for Water Transport SafetyMOSTWuhan 430063China Fraunhofer Institute for Mechanics of Materials IWM Freiburg 79108Germany

The clarification of the critical operating conditions and the failure mechanism of superlubricity systems is of great significance for seeking appropriate applications in *** this work,the superlubricity region of 1,3-diketone oil EPND(1-(4-ethyl phenyl)nonane-1,3-dione)on steel surfaces was identified by performing a series of ball-on-disk rotation friction tests under various normal loads(3.5–64 N)and sliding velocities(100–600 mm/s).The result shows that beyond certain loads or velocities superlubricity failed to be reached due to the following negative effects:(1)Under low load(≤3.5 N),insufficient running-in could not ensure good asperity level conformity between the upper and lower surfaces;(2)the high load(≥64 N)produced excessive wear and big debris;(3)at low velocity(≤100 mm/s),the weak hydrodynamic effect and the generated debris deteriorated the lubrication performance;(4)at high velocity(≥500 mm/s),oil migration occurred and resulted in oil *** order to expand the load and velocity boundaries of the superlubricity region,an optimized running-in method was proposed to avoid the above negative *** initially operating a running-in process under a suitable combination of load and velocity(e.g.16 N and 300 mm/s)and then switching to the target certain higher or lower load/velocity(e.g.100 N),the superlubricity region could break through its original *** result of this work suggests that oil-based superlubricity of 1,3-diketone is a promising solution to friction reduction under suitable operating conditions especially using a well-designed running-in strategy.

关键词： macroscopic superlubricity 1,3-diketone oil running-in process load and velocity boundaries

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SPECT imaging of distribution and retention of a brain-penetrating bispecific amyloid-β antibody in a mouse model of Alzheimer's disease

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Translational Neurodegeneration 2020年第3期9卷 473-483页

作者： tobias Gustavsson Stina Syvänen Paul O'Callaghan Dag Sehlin Department of Public Health and Caring Sciences Uppsala UniversityUppsalaSweden Department of Medical Cell Biology Uppsala UniversityUppsalaSweden

Background:Alzheimer's disease(AD)immunotherapy with antibodies targeting amyloid-B(AB)has been extensively explored in clinical *** aim of this study was to study the long-term brain distribution of two radiolabeled monoclonal Aβ antibody variants-RmAb158,the recombinant murine version of BAN2401,which has recently demonstrated amyloid removal and reduced cognitive decline in AD patients,and the bispecific RmAb158-scFv8D3,which has been engineered for enhanced brain uptake via transferrin receptor-mediated ***:A single intravenous injection of iodine-125(251)-labeled RmAb158-scFv8D3 or RmAb158 was administered to AD transgenic mice(tg-ArcSwe).In vivo single photon emission computed tomography was used to investigate brain retention and intrabrain distribution of the antibodies over a period of 4 *** in blood and brain tissue was measured ex vivo and autoradiography was performed in combination with Aβand CD31 immunostaining to investigate the intrabrain distribution of the antibodies and their interactions with ***:Despite faster blood clearance,[125]RmAb158-scFv8D3 displayed higher brain exposure than[25]RmAb158 throughout the *** brain distribution of[l25]RmAb158-scFv8D3 was more uniform and coincided with parenchymal Aβ pathology,while[2 I]RmAb158 displayed a more scattered distribution pattern and accumulated in central parts of the brain at later *** vivo autoradiography indicated greater vascular escape and parenchymal Aβ interactions for[25]RmAb158-scFv8D3,whereas[25]RmAb158 displayed retention and Aβ interactions in lateral ***:The high brain uptake and uniform intrabrain distribution of RmAb158-scFv8D3 highlight the benefits of receptor-mediated transcytosis for antibody-based brain ***,it suggests that the alternative transport route of the bispecific antibody contributes to improved efficacy of brain-directed immunotherapy.

关键词： Alzheimer's disease Amyloid beta SPECT Immunotherapy Bispecific antibody Transferrin receptor

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How to establish endoscopic submucosal dissection in Western countries

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World Journal of Gastroenterology 2015年第40期21卷 11209-11220页

作者： Tsuneo Oyama Naohisa Yahagi Thierry Ponchon tobias Kiesslich Frieder Berr Department of Endoscopy Saku Central Hospital Advanced Care Center Cancer Center Keio University School of Medicine35 ShinanomachiShinjuku-kuTokyo 160-8582Japan H?pital Edouard Herriot Specialités DigestivesPavillon HPlaced’Arsonval69437 LyonFrance Department of Medicine I University Hospital Salzburg and Institute of Physiology and PathophysiologyParacelsus Medical University

Endoscopic submucosal dissection(ESD) has been invented in Japan to provide resection for cure of early cancer in the gastrointestinal tract. Professional level of ESD requires excellent staging of early neoplasias with image enhanced endoscopy(IEE) to make correct indications for ESD,and high skills in endoscopic electrosurgical dissection. In Japan,endodiagnostic and endosurgical excellence spread through personal tutoring of skilled endoscopists by the inventors and experts in IEE and ESD. To translocate this expertise to other continents must overcome two fundamental obstacles:(1) inadequate expectations as to the complexity of IEE and ESD; and(2) lack of suitable lesions and master-mentors for ESD trainees. Leading endoscopic mucosal resection-proficient endoscopists must pioneer themselves through the long learning curve to proficient ESD experts. Major referral centers for ESD must arise in Western countries on comparable professional level as in Japan. In the second stage,the upcoming Western experts must commit themselves to teach skilled endoscopists from other referral centers,in order to spread ESD in Western countries. Respect for patients with early gastrointestinal cancer asks for best efforts to learn endoscopic categorization of early neoplasias and skills for ESD based on sustained cooperation with the masters in Japan. The strategy is discussed here.

关键词： Endoscopic submucosal dissection Early cancer Endo

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Self-referenced photonic chip soliton Kerr frequency comb

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Light(Science & Applications) 2016年第1期5卷 282-287页

作者： Victor Brasch Erwan Lucas John D Jost Michael Geiselmann tobias J Kippenberg École Polytechnique Fédérale de Lausanne(EPFL)–IPHYS Lausanne CH-1015Switzerland

Self-referencing turns pulsed laser systems into self-referenced frequency *** frequency combs allow counting of optical frequencies and have a wide range of *** required optical bandwidth to implement self-referencing is typically obtained via nonlinear broadening in optical *** advances in the field of Kerr frequency combs have provided a path toward the development of compact frequency comb sources that provide broadband frequency combs,exhibit microwave repetition rates and are compatible with on-chip photonic *** devices have the potential to significantly expand the use of frequency *** to date,self-referencing of such Kerr frequency combs has only been attained by applying conventional,fiber-based broadening *** we demonstrate external broadening-free self-referencing of a Kerr frequency *** optical spectrum spanning two-thirds of an octave is directly synthesized from a continuous wave laser-driven silicon nitride microresonator using temporal dissipative Kerr soliton formation and soliton Cherenkov *** this coherent bandwidth and two continuous wave transfer lasers in a 2f–3f self-referencing scheme,we are able to detect the offset frequency of the soliton Kerr frequency *** stabilizing the repetition rate to a radio frequency reference,the self-referenced frequency comb is used to count and track the continuous wave pump laser’s *** work demonstrates the principal ability of soliton Kerr frequency combs to provide microwave-to-optical clockworks on a chip.

关键词： frequency combs integrated optics Kerr frequency combs metrology microresonator frequency combs nonlinear optics

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Galvanically induced potentials to enable minimal tribochemical wear of stainless steel lubricated with sodium chloride and ionic liquid aqueous solution

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Friction 2018年第2期6卷 230-242页

作者： tobias AMANN Felix GATTI Natalie OBERLE Andreas KAILER Jürgen RüHE Fraunhofer Institute for Mechanics of Materials IWM Institute for Macromolecular Chemistry University of Freiburg IMTEK-Department of Microsystems Engineering University of Freiburg

The effect of galvanically induced potentials on the friction and wear behavior of a 1 RK91 stainless steel regarding to tribocorrosion was investigated using an oscillating ball-on-disk tribometer equipped with an electrochemical cell. The aim of this investigation is to develop a water-based lubricant. Therefore 1 molar sodium chloride(NaCl) and 1% 1-ethyl-3-methylimidazolium chloride [C_2 mim][Cl] water solutions were used. Tribological performance at two galvanically induced potentials was compared with the non-polarized state: cathodic potential-coupling with pure aluminum- and anodic potential-coupling with pure copper. Frictional and electrochemical response was recorded during the tests. In addition, wear morphology and chemical composition of the steel were analyzed using scanning electron microscopy(SEM) and X-ray photoelectron spectroscopy(XPS), respectively. The galvanically induced cathodic polarization of the stainless steel surface results in electrochemical corrosion protection and the formation of a tribolayer. Cations from the electrolyte(sodium Na^+ and 1-ethyl- 3-methylimidazolium [C_2 mim]^+) interact and adhere on the surface. These chemical interactions lead to considerably reduced wear using 1 NaC l(86%) and 1% 1-ethyl-3-methylimidazolium chloride [C_2 mim][Cl](74%) compared to the nonpolarized system. In addition, mechanical and corrosive part of wear was identified using this electrochemical technique. Therefore this method describes a promising method to develop water-based lubricants for technical applications.

关键词： sliding wear tribochemistry potential controlled friction and wear galvanic coupling ionic liquids tribolayer formation

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Trap catches of the sweetpotato whitefly （Homoptera： Aleyrodidae） in the Imperial Valley, California, from 1996 to 2002

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Insect Science 2007年第2期14卷 165-170页

作者： CHANG-CHI CHU EDWARD BARNES ERIC T. NATWICK TIAN-YECHEN DAVID ritter THOMAS J. HENNEBERRY USDA ARS U.S. ALARC Maricopa Arizona E1 Centro California USA Agricultural Research Cotton Inc. Cary North Carolina E1 Centro California USA University of California Cooperative Extension DANR Holtville California E1 Centro California USA Imperial County Agricultural Commissioner' s Office E1 Centro California USA

An outbreak of the sweetpotato whitefly, Bemisia tabaci （Gennadius）, biotype B occurred in the Imperial Valley, California in 1991. The insects destroyed melon crops and seriously damaged other vegetables, ornamentals and row crops. As a result of the need for sampling technology, we developed a whitefly trap （named the CC trap） that could be left in the field for extended time periods. We used the traps to monitor populations ofB. tabaci adults during year-round samplings from 1996 to 2002 to study variations in the weekly trap catches of the insect. The greatest number ofB. tabaci adults was recorded in 1996, followed by a continuing annual decrease in trap catches each year through 2002. The overall decline of B. tabaci is attributed in part to the adoption of an integrated pest management （IPM） program initiated in 1992 and reduced melon hectares from 1996 to 2002. Other factors may also have contributed to the population reductions. Seasonally, B. tabaci trap catches decreased during the late summer and fall concurrent with decreasing minimum tempera- tares that are suggested to be a significant factor affecting seasonal activity and reproduction.

关键词： Bemisia tabaci biotype B CC trap cotton melons ornamentals

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Impact of the terrestrial reference frame on the determination of the celestial reference frame

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Geodesy and Geodynamics 2019年第1期10卷 58-71页

作者： Maria Karbon Santiago Belda tobias Nilsson Institute of Geodesy and Geoinformation University of Bonn Image Processing Laboratory (IPL)-Laboratory of Earth Observation (LEO) University of Valencia Lantmateriet

Currently three up-to-date Terrestrial Reference Frames(TRF) are available, the ITRF2014 from IGN, the DTRF2014 from DGFI-TUM, and JTRF2014 from JPL. All use the identical input data of space-geodetic station positions and Earth orientation parameters, but the concept of combining these data is fundamentally different. The IGN approach is based on the combination of technique solutions, while the DGFI is combining the normal equation systems. Both yield in reference epoch coordinates and velocities for a global set of stations. JPL uses a Kalman filter approach, realizing a TRF through weekly time series of geocentric coordinates. As the determination of the CRF is not independent of the TRF and vice versa, the choice of the TRF might impact on the CRF, Within this work we assess this *** find that the estimated Earth orientation parameter(EOP) from DTRF2014 agree best with those from ITRF2014, the EOP resulting from JTRF2014 show besides clear yearly signals also some artifacts linked to certain stations. The estimated source position time series however, agree with each other better than ±1 μas. When fixing EOP and station positions we can see the maximal effect of the TRF on the CRF. Here large systematics in position as well as proper motion arise. In case of ITRF2008 they can be linked to the missing data after 2008. By allowing the EOP and stations to participate in the adjustment,the agreement increases, however, systematics remain.

关键词： Reference frames CRF TRF DTRF2014 JTRF2014 ITRF2014

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Assessing quality of volunteer crowdsourcing contributions:lessons from the Cropland Capture game

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International Journal of Digital Earth 2016年第4期9卷 410-426页

作者： Carl F.Salk tobias Sturn Linda See Steffen Fritz Christoph Perger Ecosystems Services and Management Program International Institute for Applied Systems AnalysisLaxenburgAustria Southern Swedish Forest Research Center Swedish University of Agricultural SciencesAlnarpSweden

Volunteered geographic information(VGI)is the assembly of spatial information based on public *** VGI has proliferated in recent years,assessing the quality of volunteer-contributed data has proven challenging,leading some to question the efficiency of such *** this paper,we compare several quality metrics for individual volunteers’*** data were the product of the‘Cropland Capture’game,in which several thousand volunteers assessed 165,000 images for the presence of cropland over the course of 6 *** compared agreement between volunteer ratings and an image’s majority classification with volunteer self-agreement on repeated images and expert *** also examined the impact of experience and learning on *** self-agreement was nearly always higher than agreement with majority classifications,and much greater than agreement with expert validations although these metrics were all positively *** quality showed a broad trend toward improvement with experience,but the highest accuracies were achieved by a handful of moderately active contributors,not the most active *** results emphasize the importance of a universal set of expert-validated tasks as a gold standard for evaluating VGI quality.

关键词： crowdsourcing volunteered geographic information cropland data quality image classification Geo-Wiki

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UV-LED projection photolithography for high-resolution functional photonic components

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Microsystems & Nanoengineering 2021年第4期7卷 149-159页

作者： Lei Zheng Urs Zywietz tobias Birr Martin Duderstadt Ludger Overrmeyer Bernhard Roth Carsten Reinhardt Hannover Centre for Optical Technologies Leibniz University HannoverHannoverLower Saxony 30167Germany Cluster of Excellence PhoenixD(Photonics Opticsand Engineering-Innovation Across Disciplines)HannoverLower Saxony 30167Germany Laser Zentrum Hannover e.V HannoverLower Saxony 30167Germany Institute of Transport and Automation Technology Leibniz University HannoverGarbsenLower Saxony 30823Germany Bremen University of Applied Science BremenBremen 28199Germany

The advancement of micro-and nanostructuring techniques in optics is driven by the demand for continuous miniaturization and the high geometrical accuracy of photonic devices and integrated ***,UV-LED projection photolithography is demonstrated as a simple and low-cost approach for rapid generation of two-dimensional optical micro-and nanostructures with high resolution and accuracy using standard optics *** developed system enables the projection of structure patterns onto a substrate with 1000-fold *** devices,e.g.,waveguides and microring resonators,on rigid or flexible substrates with varied geometrical complexity and overall structure dimensions from the nanometer to centimeter scale were successfully *** particular,high-resolution gratings with feature sizes down to 150 nm and periods as small as 400 nm were realized for the first time by this *** made of doped laser active materials were fabricated,and their spontaneous emission was *** demonstrated superior performance of the developed approach may find wide applications in photonics,plasmonics,and optical materials science,among others.

关键词： projection resolution optics

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激变变星

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天文学进展 1991年第4期9卷 279-288页

作者： Hans ritter 联邦德国马克斯普朗克物理和天体物理研究所

一、引言激变变星(Cataclysmie Variables)这一奇怪的名字出现于约40年前,当时***-Gaposchkin和***把具有周期性且非毁灭性爆发的变星称为激变变星(简称CVs),并分类为:

关键词：变星激变

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