检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

慢生活,慢美好

现代装饰 2021年第2期 100-109页

作者： Midgard licht Stefan Diez Miniforms Yiannis Ghikas Garda Furniture Devon&Devon Massimo Iosa Ghini Paolo Cappello Simone Sabatti Studio Elk Gantri Caleido Giuseppe Bavuso Stellar Works Space Copenhagen tobias grau Flos La Manufacture Foscarini Andrea Anastasio Chaosteria 郭映琴 AM Studio Nendo

台湾漫画家朱德庸是慢生活的典范,他曾言道:"这是一个每个人都在跑的时代,但是我坚持用自己的步调慢慢走。"慢生活,是一种生活态度,身处高楼林立、车水马龙的人们,往往需要适当地放慢脚步,找到工作和生活的平衡点,张弛有度,提升生活的...

台湾漫画家朱德庸是慢生活的典范,他曾言道:"这是一个每个人都在跑的时代,但是我坚持用自己的步调慢慢走。"慢生活,是一种生活态度,身处高楼林立、车水马龙的人们,往往需要适当地放慢脚步,找到工作和生活的平衡点,张弛有度,提升生活的幸福感。近些年来,家居产品的设计不单单考量其实用性、便捷度,同时还趋向于关注产品本身对人的"治愈"作用;本期摘选的产品结合科技、创意新元素,将美好注入点滴日常,自然而然地引导人们松弛下来,在慢生活中觅得慢美好。

关键词：

Can minimal running shoes imitate barefoot heel-toe running patterns?A comparison of lower leg kinematics

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2014年第2期3卷 67-73,152+156页

作者： tobias Hein Stefan grau Department of Food and Nutrition and Sport ScienceUniversity of Gothenburg Medical Clinic Department of Sports MedicineUniversity of Tuebingen

Background:Numerous studies about the interaction between footwear(and barefoot) and kinematic and kinetic outcomes have been published over the last few *** studies however lead to the conclusion that the assumed interactions depend mainly on the subjects" experience of barefoot(BF) walking/running,the preferred running strike pattern,the speed,the hardness of the surface,the thickness of the midsole material,and the runners’ level of *** aim of the present study was to investigate lower leg kinematics o\’ BF running and running in minimal running shoes(MRS) to assess comparability of BF kinematics in both *** systematically compare both conditions we monitored the influencing variables described above in our measurement *** hypothesized that running in MRS does not alter lower leg kinematics compared to BF ***:Thirty-seven subjects,injury-free and active in sports,ran BF on an EVA foam runway,and also ran shod wearing Nike Free 3.0 on a tartan indoor ***-leg 3D kinematics was measured to quantify rearfoot and ankle *** markers were used in both shod and BF ***:All runners revealed rearfoot strike pattern when running *** between BF and MRS running occurred particularly during the initial stance phase of running,both in the sagittal and the frontal *** running revealed a flatter foot placement,a more plantar flexed ankle joint and less inverted rearfoot at touchdown compared to MRS ***:BF running does not change the landing automatically to forefoot running,especially after a systematic exclusion of surface and other influencing *** Nike Free 3.0 mimics some BF ***,changes in design of the Nike Free should be considered in order to mimic BF movement even more closely.

关键词： 3D-kinematics Ankle Barefoot Minimal running shoes Rearfoot Running

Real-World Evidence in Localized Pancreatic: Coping with Uncertainty in Unselected Populations

在线全文

学校读者我要写书评

暂无评论

Journal of Cancer Therapy 2024年第4期15卷 164-178页

作者： María I. Pamies Ramón Diana Ibarra Anguita Paula Rodríguez Payá Alvaro Muñoz Abad David Sánchez García María Valero Revert Beatriz grau Mirete Mariano Martínez Marín Alicia Calero Amaro Lorena Rodríguez Cazalla Javier Gallego Plazas Medical Oncology Department Elche University Hospital Elche (Alicante) Spain General Surgery Department Elche University Hospital Elche (Alicante) Spain General Surgery Department Vega Baja Hospital Orihuela (Alicante) Spain

Background: Localized pancreatic cancer, including resectable (R), borderline resectable (BR) and locally advanced unresectable disease (LAU), is considered in clinical guidelines for diverse treatment options based on clinical trials in selected populations. Hence, exploring with real world evidence (RWE) clinicians’ preferences for treatment options and their results seems pertinent. Methods: In a set of consecutive patients with localized pancreatic cancer assisted in a third level hospital from January 2013 to December 2022, medical records, symptoms, diagnostic process, distribution between subtypes, and treatment plans, with safety and efficacy results, were assessed. Results: A total of 152 patients with localized disease were included (43.4% R, 21.0% BR, 33.6% LAU). The population characteristics exemplified differences between daily practice and clinical trials. Tumor location and symptoms were as expected. Treatment plan was conditioned by PS or comorbidities in 23.0% of patients. In patients with R disease, surgery followed by different adjuvant chemotherapy (CT) regimes was the antineoplastic treatment of choice (64.8%) with efficacy results (OS 37.5 months;95% CI 18.4 - 56.7), in the range of contemporary standards. The common use of neoadjuvant CT for BR disease (94.4%), with surgery in 50% of them, and its results (OS 30.8 months;95% CI 10.5 - 51.2) reflected current controversies of treatment recommendations and evolution in this scenario. Paliative CT with or without radiotherapy was the standard specific treatment in LAU disease (95.1%) with survival results (PFS: 10.8 months;95% CI 8.8 - 12.7. OS: 20.3 months;95% CI 13.5 - 27.2) that justify the distinct character and the specific study of this entity. Conclusion: RWE for localized pancreatic cancer aroused from the analysis of this population confirms the distinct nature of patients assisted in daily practice, as well as mirrors the complexity of decision making in clinical assumptions in which a

关键词： Real-World Evidence Localized Pancreatic Cancer

Effect of Microalloying,Principally With Vanadium,Processing Conditions and Microstructure on Resistance to CO_2 Corrosion

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2011年第S1期18卷 183-191页

作者： Edmonds David Cochrane Robert grau Rosa Institute for Materials Research University of LeedsLeedsLS2 9JTUK Mikalor BarcelonaSpain

One driver for steel development over recent decades has been the engineering requirements of improved strength and toughness,combined with weldability,for the safe and cost effective recovery and transmission of oil and *** has been achieved through refinement of grain size by microalloy precipitation and thermomechanical ***,little attention has been paid to these significant changes in steel chemistry and processing on corrosion resistance,despite the dominance of economic carbon steel for construction in the oil and gas *** more common forms of corrosion are associated with the presence of H 2 S or CO *** 2 in aqueous solution forms a weak acid sufficient to promote significant localized corrosion in transmission gas/oil pipelines and in well-head applications (’down-hole’).Systematic study has identified the influence of a wide range of alloying elements and different processing conditions on the resistance of low-carbon steels to CO 2 corrosion;strong carbide-forming microalloying elements such as Ti,Nb and V,along with Cr additions,and different levels of Mn,Si,Cu,Mo and Ni,have been explored,along with treatments simulating different processing *** present study also emphasizes the role of V and Ti microalloying in improving the resistance of Cr-containing carbon steel to corrosion in carbonic acid and how this is influenced by microstructure and the metallurgical condition of the microalloying addition,in particular,the extent of *** is noted that some commercially available corrosion inhibitors contain V as a vanadate compound to interfere with the corrosion process and so it is suggested that V microalloying may also be beneficial if present in an appropriate form in the *** Ti also seems to play a role in corrosion in the steels studied is judged to be compatible with the thermodynamics of transition metal anions in the Ti-V-Cr group.

关键词： microalloying vanadium processing corrosion carbonic acid

Sex dimorphism and metabolic profiles in management of metabolic-associated fatty liver disease

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2023年第6期11卷 1236-1244页

作者： Maria Martin-grau Daniel Monleon Department of Pathology University of ValenciaValencia 46010Spain

Metabolic-associated fatty liver disease(MAFLD)refers to the build-up of fat in the liver associated with metabolic dysfunction and has been estimated to affect a quarter of the population *** metabolism is highly influenced by the effects of sex hormones,studies of sex differences in the incidence and progression of MAFLD are *** represents a powerful approach to studying these differences and identifying potential biomarkers and putative ***,metabolomics makes it possible to obtain the molecular phenotype of the individual at a given ***,metabolomics may be a helpful tool for classifying patients according to the severity of the disease and obtaining diagnostic *** studies demonstrate associations between circulating metabolites and early and established MAFLD,but little is known about how metabolites relate to and encompass sex differences in disease progression and risk *** this review,we will discuss the epidemiological metabolomic studies for sex differences in the development and progression of MAFLD,the role of metabolic profiles in understanding mechanisms and identifying sex-dependent biomarkers,and how this evidence may help in the future management of the disease.

关键词： MAFLD Sex differences Metabolic profiles Metabolism

The role of small vessel disease in development of Alzheimer's disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2010年第4期5卷 310-320页

作者： Marta grau-Slevin Adria Arboix John Gaffney Mark Slevin School of Biology Chemistry and Health ScienceManchester Metropolitan University Cerebrovascular Division Department of NeurologyHospital Universitari del Sagrat CorUniversitat de Barcelona

Classically Alzheimer＇s disease and vascular dementia have been considered as two different entities, with their own clinical criteria, but relatively recent epidemiological and clinicopathological studies suggest an overlap between them sharing not only most of the risk factors and some clinical aspects but also pathophysiological mechanisms. Cerebrovascular lesions, especially small vessel disease （lacunar infarcts, white matter hyperintensities and microbleeds）, may magnify the effects of mild Alzheimer＇s disease pathology and promote the progression of cognitive decline and may also be a precursor of neuronal damage and dementia. ＂Vascular hypothesis＂ of Alzheimer＇s disease would open a window for new approaches and treatments.

关键词： Alzheimer's disease small vessel disease development risk factors diagnosis neuroimaging studies histopathological studies neurodegenerative disease neural regeneration

Distributed representations of atoms and materials for machine learning

在线全文

学校读者我要写书评

暂无评论

npj Computational Materials 2022年第1期8卷 415-423页

作者： Luis M.Antunes Ricardo grau-Crespo Keith T.Butler Department of Chemistry University of ReadingWhiteknightsReadingRG66DXUK SciML Scientific Computing DepartmentRutherford Appleton LaboratoryHarwellOX110QXUK

The use of machine learning is becoming increasingly common in computational materials *** build effective models of the chemistry of materials,useful machine-based representations of atoms and their compounds are *** derive distributed representations of compounds from their chemical formulas only,via pooling operations of distributed representations of *** compound representations are evaluated on ten different tasks,such as the prediction of formation energy and band gap,and are found to be competitive with existing benchmarks that make use of structure,and even superior in cases where only composition is ***,we introduce an approach for learning distributed representations of atoms,named SkipAtom,which makes use of the growing information in materials structure databases.

关键词： representations operations competitive

On a Variant of Giuga Numbers

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2012年第4期28卷 653-660页

作者： Jos María grau Florian LUCA Antonio M. OLLER-MARCN Departmento de Matemáticas Universidad de Oviedo Avda. Calvo Sotelo s/n Instituto de Matemáticas Universidad Nacional Autnoma de México The John Knopfmacher Centre for Applicable Analysis and Number Theory University of the Witwatersrand Centro Universitario de la Defensa Academia General Militar Ctra. Huesca s/n

In this paper, we characterize the odd positive integers n satisfying the congruence ∑j=1^n-1 j n-1/2 We show that the set of such positive integers has an asymptotic densitywhich turns out to be slightly larger than... 详细信息

关键词： Congruence Giuga numbers asymptotic density

Ocular trauma in an urban Spanish population:epidemiology and visual outcome

在线全文

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2021年第9期14卷 1327-1333页

作者： Marta Belmonte-grau Guadalupe Garrido-Ceca Paula Marticorena-álvarez Department of Ophthalmology Hospital Universitario de La PrincesaMadrid 28006Spain Universidad Autónoma de Madrid Medicine UniversityMadrid 28006Spain

AIM:To describe epidemiological aspects,clinical findings,and visual results in eye trauma patients requiring urgent surgery at a tertiary ***:Retrospective review of adult patients requiring urgent surgery for trauma to the eyeball from January 2010 and April *** was collected relative to age,gender,mechanism of the injury,type of wound,initial and final visual acuity,number and type of surgeries carried *** were classed according to the Birmingham Eye Trauma Terminology(BETT)and the Ocular Trauma Score(OTS)***:The survey included 92 *** age was 54.76±22.18 *** most frequent cause was domestic accidents(44.6%),followed by aggression(22.80%)and occupational accidents(17.4%).Trauma from aggression was more frequent in men(P=0.006)and accidents in the home more common in women(P=0.011).Patients over 65 y presented an odds ratio(OR)of 10.71 for suffering a domestic *** between 15-45 and 46-65 y were at higher risk of trauma from aggression(OR=17.52 and OR=10.94,respectively).As for the type of injury,63.04%were open-globe lesions,Zone II being the most frequently affected(27.2%).In Logistic regression analysis,old age(P=0.05)and retinal involvement(P=0.001)were found to be associated with higher rate of unfavourable visual ***:The epidemiological aspects of eye trauma are highly dependent on the area of population *** accidents are more relevant than workplace accidents in older urban areas with high socioeconomic status.A better knowledge of the epidemiological characteristics is useful for implementing specific prevention measures and appropriate treatment strategies.

关键词： ocular trauma epidemiology domestic accident