检索结果-南通市图书馆

基于自适应时间窗函数优化的心电特征波形识别

在线全文

学校读者我要写书评

暂无评论

北京邮电大学学报 2019年第4期42卷 82-88页

作者：张金玲崔彤刘为斌北京邮电大学电子工程学院

提出了自适应加窗小波变换方法,实现了心电特征波形精准定位.依据Q波和S波变化趋势识别出心电波有效起始点和终止点;结合差分阈值法检测QRS起始点,实现了心电特征波段的信息识别.研究结果表明,采用提出的定位识别方法,能对异常和亚健康... 详细信息

提出了自适应加窗小波变换方法,实现了心电特征波形精准定位.依据Q波和S波变化趋势识别出心电波有效起始点和终止点;结合差分阈值法检测QRS起始点,实现了心电特征波段的信息识别.研究结果表明,采用提出的定位识别方法,能对异常和亚健康心电波形进行有效识别,提高对QRS波群、特征P波和T波的识别度,对心电信息的提取和异常性心绞痛、心肌缺血、不稳定型心绞痛等心电异常诊断具有重要意义.

关键词：自适应加窗小波变换差分阈值心电信号特征波形识别

PrkA negatively regulates the temperature tolerance and virulence of Aeromonas veronii

在线全文

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2024年

作者： Yuanhuan Kang Jianping Wei Bintong Yang tong Zhao Haiying cui Shu Li Wei Cong Marine College， Shandong University/Key Laboratory of Modern Marine Ranching Technology of Weihai Shandong Key Laboratory of Animal Microecological Preparation College of Veterinary Medicine/College of Animal Science and Technology， Jilin Agricultural University

Aeromonas veronii is considered an emerging food-borne pathogen associated with a significant threat to public health， distributing in various aquatic environments and aquatic products. Hanks-type Ser/Thr kinases (STKs) play a critical role in the pathogenesis of pathogens. However， the function of A. veronii STKs is currently unclear. By constructing a markerless prkA in-frame deletion strain， ΔprkA， we found that (i) the colonies of the ΔprkA strain were larger after 1 h of high temperature at 50 ℃ compared with the wild-type strain TH0426 and the complementary strain C-prkA， and the number of viable bacteria of the ΔprkA strain increased significantly (P < 0.001); (ii) the ΔprkA strain significantly enhanced the adhesion ability to epithelioma papulosum cyprini (EPC) cells; (iii) the ΔprkA strain was significantly more virulent than the TH0426 strain， at both the cellular and animal levels; and (iv) RNA-seq results showed a total of 984 differentially expressed genes (DEGs) between the ΔprkA strain and the TH0426 strain， which were enriched in 70 KEGG metabolic pathways， mainly involved in bacterial ribosomes， flagellar assembly， type II secretion system (T2SS)， and lipopolysaccharide metabolic pathways. Taken together， the findings of this study indicate that the Hanks-type STK PrkA negatively regulates several biological processes， such as the temperature tolerance and virulence of A. veronii. The results of this study provide an important reference for further elucidation of the pathogenesis of A. veronii.

关键词：

Chromosome-scale genome assembly-assisted identification of Brassica napus BnDCPA1 for improvement of plant architecture and yield heterosis

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Plant Communications 2024年第7期5卷 1-4页

作者： Chuanji Zhao Xiaobo cui Meili Xie Yi Zhang Lingyi Zeng Yueying Liu Junyan Huang Xiong Zhang Chaobo tong Qiong Hu Lijiang Liu Shengyi Liu Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences Key Laboratory of Biology and Genetic Improvement of Oil CropsMinistry of Agriculture and Rural AffairsWuhanChina These authors contributed equally to this article

Plant architecture can act as a pivotal determinant of crop yield by maximizing photosynthate accumulation in grains,but no *** rapeseed ideotype has yet been ***,semi-dwarf and compact(SDC)rapeseed plant types with the capacity to maximize silique number per hectare and seed weight per silique are expected to optimize plant architecture for groundbreaking seed yield,avoiding lodging and promoting mechanical harvest(Liu et al.,2022).In this study,we report the mutant dc1,which exhibits DC plant architecture with significantly increased silique number in the main inflorescence compared with currently cultivated high and loose(HL)plant types like those of elite cultivars(Figure 1A and Supplemental Figure 1).

关键词： elite cultivar dwarf

动力和统计预测信息融合预测方法及对我国夏季降水预测的检验

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

地球物理学报 2019年第11期62卷 4110-4119页

作者：孙丞虎崔童李维京左金清中国气象科学研究院灾害天气国家重点实验室及气候与气候变化研究所北京100081 南京信息工程大学气象灾害预报预警与评估协同创新中心南京210044 国家气候中心气候研究开放实验室北京100081

短期气候预测中如何将气候模式和统计方法的预测结果科学、客观的集成起来,一直是非常重要的问题.本文针对动力模式和统计方法预测结果相结合的问题,引入资料同化中信息融合的思想,采用最优内插同化方法,实现了动力模式和统计季节降水... 详细信息

短期气候预测中如何将气候模式和统计方法的预测结果科学、客观的集成起来,一直是非常重要的问题.本文针对动力模式和统计方法预测结果相结合的问题,引入资料同化中信息融合的思想,采用最优内插同化方法,实现了动力模式和统计季节降水预测结果的融合.检验表明,对1982—2015年我国夏季降水百分率的回报,融合预测结果与观测的平均空间相关系数可达0.44,分别较统计预测和CFSv2模式统计降尺度订正的技巧提高了0.1左右,而均方根误差较两者可以降低5%~20%.可见,该方法可以进一步提升对我国夏季降水的预测技巧,具有显著的业务应用价值.

关键词：中国夏季降水统计预测动力模式预测融合

Visible Light-Induced Collapse of Molecular Microcrystals into Droplets by E-to-Z Photoisomerization and Melting Phase Transition

在线全文

学校读者我要写书评

暂无评论

CCS Chemistry 2024年第4期6卷 1071-1084页

作者： Tian-Yi Xu Min cui Chengxi Zhao Shang-Wu Zhou Tian-Le Zhang Hui-Yao Lin Fei tong Da-Hui Qu Key Laboratory for Advanced Materials and Feringa Nobel Prize Scientist Joint Research Center School of Chemistry and Molecular EngineeringEast China University of Science and TechnologyShanghai 200237

Harnessing photoresponsive behavior in organic crystals,such as shape and morphology deformation,on multiple scales is intriguing with respect to precise spatiotemporal operation,because dynamic deformations are promising in fabricating future intelligent ***,we synthesized a new photoresponsive molecular crystal composed of dimethyl(E)-2-(3-(naphthalen-1-yl)allylidene)malonate((E)-DNAM)that undergoes E-to-Z photoisomerization accompanied by photoinduced crystal-to-liquid melting phase transition when exposed to visible *** of expanding in bulk polycrystals,single-crystal(E)-DNAM rectangular microplates in an aqueous solution rapidly collapsed into liquid droplets,showing a remarkable drastic reduction in surface area of more than 97%after light *** deduce that the unique microscopic morphology of microplates with high aspect ratios of length-tothickness reaching up to 1000 is mainly responsible for the photoinduced melting leading to drastic *** addition,the cohesive forces of liquid photoproduct facilitate the overall deformations and *** have shown a facile way to achieve the remarkable collapse of molecular crystals into droplets by photochemical reaction and phase transition.

关键词： molecular crystals crystal-to-liquid transition extreme deformations photochemistry crystal engineering flexible crystals

A simple and efficient CRISPR/Cas9 system permits ultra-multiplex genome editing in plants

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Crop Journal 2024年第2期12卷 569-582页

作者： Suting Wu Htin Kyaw Zhijun tong Yirong Yang Zhiwei Wang Liying Zhang Lihua Deng Zhiguo Zhang Bingguang Xiao William Paul Quick Tiegang Lu Guoying Xiao Guannan Qin Xue'an cui Biotechnology Research Institute Chinese Academy of Agricultural SciencesBeijing 100081China Key Laboratory of Genetics Breeding and Multiple Utilization of CropsMinistry of EducationCollege of AgricultureFujian Agriculture and Forestry UniversityFuzhou 350002FujianChina Key Laboratory of Biological Breeding for Fujian and Taiwan Crops Ministry of Agriculture and Rural AffairsCollege of AgricultureFujian Agriculture and Forestry UniversityFuzhou 350002FujianChina Key Laboratory of Agro-ecological Processes in Subtropical Region Institute of Subtropical AgricultureChinese Academy of SciencesChangsha 410125HunanChina School of Biosciences The University of SheffieldFirth CourtWestern BankSheffield S102TNUK Key Laboratory of Tobacco Biotechnological Breeding National Tobacco Genetic Engineering Research CenterYunnan Academy of Tobacco Agricultural SciencesKunming 650021YunnanChina

The development and maturation of the CRISPR/Cas genome editing system provides a valuable tool for plant functional genomics and genetic *** available genome-editing tools have a limited number of targets,restricting their application in genetic *** this study,we developed a novel CRISPR/Cas9 plant ultra-multiplex genome editing system consisting of two template vectors,eight donor vectors,four destination vectors,and one primer-design software *** combining the advantages of Golden Gate cloning to assemble multiple repetitive fragments and Gateway recombination to assemble large fragments and by changing the structure of the amplicons used to assemble sg RNA expression cassettes,the plant ultra-multiplex genome editing system can assemble a single binary vector targeting more than 40 genomic loci.A rice knockout vector containing 49 sg RNA expression cassettes was assembled and a high co-editing efficiency was *** plant ultra-multiplex genome editing system advances synthetic biology and plant genetic engineering.

关键词： CRISPR/Cas9 Multiplex genome editing Assembly system Plant

Controllable synthesis of a self-assembled ultralow Ru,Ni-doped Fe_(2)O_(3) lily as a bifunctional electrocatalyst for large-current-density alkaline seawater electrolysis

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Catalysis 2022年第8期43卷 2202-2211页

作者： tong cui Xuejun Zhai Lili Guo Jing-Qi Chi Yu Zhang Jiawei Zhu Xuemei Sun Lei Wang Key Laboratory of Eco-chemical Engineering Ministry of EducationInternational Science and Technology Cooperation Base of Eco-chemical Engineering and Green ManufacturingCollege of Chemistry and Molecular EngineeringQingdao University of Science and TechnologyQingdao 266042ShandongChina College of Chemical Engineering Qingdao University of Science and TechnologyQingdao 266042ShandongChina College of Environment and Safety Engineering Qingdao University of Science and TechnologyQingdao 266042ShandongChina

Highly efficient and stable bifunctional electrocatalysts that can be used for large-current-density electrolysis of alkaline seawater are highly desirable for carbon-neutral economies,but their facile and controllable synthesis remains a ***,self-assembled ultralow Ru,Ni-doped Fe_(2)O_(3) with a lily shaped morphology was synthesized on iron foam(RuNi-Fe_(2)O_(3)/IF)via a facile one-step hydrothermal process,in which the intact lily shaped RuNi-Fe_(2)O_(3)/IF was obtained by adjusting the ratio of Ru/*** from the Ru/Ni chemical substitution,the as-synthesized RuNi-Fe_(2)O_(3)/IF can act as free-standing dual-function electrodes that are applied to electrocatalysis for the hydrogen evolution(HER)and oxygen evolution reactions(OER)in 1.0 mol L^(-1) KOH,requiring an overpotential of 75.0 mV to drive 100 mA cm^(-2) for HER and 329.0 mV for ***,the overall water splitting catalyzed by RuNi-Fe_(2)O_(3)/IF only demands ultralow cell voltages of 1.66 and 1.73 V to drive 100 mA cm^(-2) in 1.0 mol L^(-1) KOH and 1.0 mol L^(-1) KOH seawater electrolytes,*** electrodes show remarkable long-term durability,maintaining current densities exceeding 100 mA cm^(-2) for more than 100 h and thus outperforming the two-electrode system composed of noble *** work provides an efficient,economical method to synthesize self-standing bifunctional electrodes for large-current-density alkaline seawater electrolysis,which is of significant importance for ecological protection and energy exploitation.

关键词： RuNi-Fe_(2)O_(3)/IF Lily shape Bifunctional electrocatalyst Alkaline seawater splitting Large current density

在线全文

学校读者我要写书评

暂无评论

弹性体力/触觉框架模型

计算机辅助设计与图形学学报 2010年第2期22卷 198-203页

作者：崔桐宋爱国张小瑞陆熊东南大学仪器科学与工程学院南京210096 中国电子科技集团公司第二十八研究所南京210007 南京信息工程大学信息与控制学院南京210044

在力/触觉建模技术中,高效的实时性与基于物理意义的准确性是与生俱来的一对矛盾.为了提高实时性与准确性的和谐程度,提出一种分析虚拟柔性体力/变形关系的框架结构模型.在柔性体内部建立一定数量并相互独立的钢架结构,运用虚功原理计... 详细信息

在力/触觉建模技术中,高效的实时性与基于物理意义的准确性是与生俱来的一对矛盾.为了提高实时性与准确性的和谐程度,提出一种分析虚拟柔性体力/变形关系的框架结构模型.在柔性体内部建立一定数量并相互独立的钢架结构,运用虚功原理计算每根钢架上节点的位移;根据接触点和节点的分布,采用分水岭法将柔性体表面分割成若干区域,通过本区域内节点和接触点的位移插值计算区域内顶点的变形,进而得到柔性体的整体变形.仿真实验结果表明,该模型简便、实时性好,在具体的虚拟建模力反馈工作中可操作性强.

关键词：框架结构力/触觉再现力反馈钢架模型虚拟现实

血清鳞状细胞癌抗原和癌胚抗原联合检测对子宫颈癌的诊断及疗效评价

在线全文

学校读者我要写书评

暂无评论

肿瘤研究与临床 2016年第8期28卷 513-518页

作者：崔桐韩存芝山西医科大学附属肿瘤医院放射治疗中心太原030013 山西省肿瘤研究所病因室太原030013

目的探讨鳞状细胞癌抗原（SCC-Ag）和癌胚抗原（CEA）联合检测对子宫颈癌的诊断、疗效评估、病情监测及预后分析的意义.方法收集经病理确诊的子宫颈癌患者424例,妇科良性病患者400例,酶联免疫吸附法检测SCC-Ag和CEA水平,同时收集子宫... 详细信息

目的探讨鳞状细胞癌抗原（SCC-Ag）和癌胚抗原（CEA）联合检测对子宫颈癌的诊断、疗效评估、病情监测及预后分析的意义.方法收集经病理确诊的子宫颈癌患者424例,妇科良性病患者400例,酶联免疫吸附法检测SCC-Ag和CEA水平,同时收集子宫颈癌患者的盆腔彩色超声检查结果并进行分析.结果子宫颈癌组血清SCC-Ag、CEA及二者联合检测的阳性率[55.9 ％（237 /424）、26.4％（112/424）、61.8％（262/424）]均高于良性病组[12.0％（48/400）、12.5％（50/400）、14.5％（58/400）]（均P＜ 0.05）.SCC-Ag和CEA联合检测对子宫颈癌诊断的灵敏度（61.8％）高于CEA、SCC-Ag单项检测（55.9％、26.4％）（均P＜ 0.05）.治疗前血清SCC-Ag、CEA水平在不同的临床分期、病理分型、浸润深度及淋巴结是否转移的子宫颈癌患者间的差异均有统计学意义（均P＜ 0.05）.Ⅰ、Ⅱ期子宫颈癌患者SCC-Ag与CEA联合检测的阳性率[45.5％（71/156）、73.2％（139/190）]高于超声检查[33.3％（52/156）、51.1％（97/150）]（P＜ 0.05）.手术、同步放化疗和手术联合放化疗治疗后SCC-Ag水平（中位数为0.34、0.51、0.33 ng/ ml）低于治疗前（0.48、3.44、1.29 ng/ml）,CEA治疗后水平（中位数为0.75、0.81、0.71 ng/ ml）低于治疗前（1.22、1.53、1.50 ng/ ml）（P＜ 0.05）.三种方式治疗后,SCC-Ag、CEA水平升高及未降至正常范围的子宫颈癌患者中分别有33.3 ％（6/18）、56.5％（13/23）和46.1％（35/76）复发或转移.SCC-Ag阳性患者的生存率低于阴性患者（P＜0.05）,而CEA阳性和阴性患者的生存率差异无统计学意义（P＞0.05）.结论 SCC-Ag和CEA联合检测可作为子宫颈癌辅助诊断的首选标志物.SCC-Ag和CEA联合检测可以作为临床分期、病理分型、浸润深度、淋巴结转移及疗效评价、预后判断的重要指标.对于Ⅰ、Ⅱ期子宫颈癌患者SCC-Ag和CEA联合检测的阳性率高于盆腔超声检查.

关键词：子宫颈肿瘤肿瘤标记,生物学诊断治疗结果