检索结果-南通市图书馆

Thyroid Nodule: Alpha Score 2.0 Classification for FNAB Selection, Multicentric Study in Latin America

Open Journal of Radiology 2021年第4期11卷 160-174页

作者： Glenn Mena Maria Cristina Chammas Carlos Mario Gonzalez Vasquez Lylian Rocío Villagómez Marco Alfredo Muñoz Pico Patricio Alejandro Montalvo Santiago Mena-Bucheli Julio Olmedo Elizabeth Quintero Pedro Henrique de Marqui Moraes Osmar Cassio saito Hubertino Diaz Denise Romero Gabriela Velalcazar Angel Ramón Sosa Fleitas Yamil Oliver Quevedo Ontaneda Victor Ricardo Chara Alpha Imagen Radiología e Intervencionismo Quito Ecuador Hospital das Clínicas Faculdade de Medicina da Universidade de Sã o Paulo S&#227 o Paulo Brasil Hospital Pablo Tobón Uribe Medellin Colombia Hospital del Instituto Ecuatoriano de Seguridad Social Quito Sur Quito Ecuador Hospital San Francisco de Quito Quito Ecuador Hospital Edgardo Rebagliati Martins Lima Perú Hospital Carlos Andrade Marín Quito Ecuador Hospital de Clínicas San José de San Martín Buenos Aires Argentina Hospital Universitario de Los Andes Mérida Venezuela Hospital de la Policía Quito Ecuador Hospital Sisol Tacna Perú

Introduction: To perform a Latin-American multicentric study for the prediction of benign and malignant thyroid nodules using Alpha Score, and to compare it with ACR TIRADS® and Bethesda®. Materials and Methods: A prospective multicentric study in 10 radiological hospitals and institutions of Latin America was performed and 818 thyroid nodules were analyzed by ultrasound and classified by using both ACR TIRADS® and Alpha Score;fine-needle aspiration biopsy was performed when needed and classified with Bethesda. The relationships between predictors were analyzed by using binary logistic regression, statistical significance was defined by a p-value of 0.05, with an error margin of 4% and 95% confidence intervals. Results: Alpha Score 2.0 establishes five types of malignant predictors: microcalcifications, irregular borders, taller-than-wide shape, predominant solid texture and hypoechogenicity;a diameter equal to or greater than 1.5 cm adds an extra point to the final score. Resulting classification divides TNs into 4 categories: benign (1.9%), low suspicion (8.7%), mild suspicion (13.6%) and high suspicion (75.7%) of malignancy probability;sensitivity of 82%, specificity of 74%, the positive predictive value of 94%, the negative predictive value of 51%, the statistical accuracy of 81%, odds ratio of 108.89 and correlation with ACR TIRADS of 0.77 and Bethesda of 0.91. Conclusions: Alpha Score 2.0 has superior diagnostic accuracy and performance compared to the previously published Alpha Score and is able to classify a benign TN in a precise, safe and accurate way, avoiding unnecessary FNABs or determining the necessity of FNAB in cases of moderate to high suspicion of malignancy.

关键词： Thyroid Cancer-Clinical Radiology-Imaging Thyroid Nodule Alpha Score TIRADS® Thyroid Ultrasonography

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

钢包炉法和等离子熔化与精炼法

引用

钢铁 1982年第2期 62-68页

作者：山口国南顾德骥大同制钢公司研究所

1. 钢包炉法发展的历史于1971年4月设置的大同制钢公司的第一座钢包炉(LF)是20 t的钢包,带有4500KVA变压器,三个直径为10in(254mm)电极的氩气搅拌装置和真空抽气设备.在1973年7月建设了容量也是20t的第二座钢包炉,专用以精炼不锈钢,是... 详细信息

1. 钢包炉法发展的历史于1971年4月设置的大同制钢公司的第一座钢包炉(LF)是20 t的钢包,带有4500KVA变压器,三个直径为10in(254mm)电极的氩气搅拌装置和真空抽气设备.在1973年7月建设了容量也是20t的第二座钢包炉,专用以精炼不锈钢,是将在电弧炉中脱过碳的不锈钢液与氧化渣一起移入钢包以进行搅拌.当铬被还原后即倾侧钢包除去炉渣,然后加入新的造渣剂以最终精炼.这种操作不需要真空抽气系统,而我们的目的在于降低原材料价格和提高电弧炉生产率.

关键词：钢包炉渣碱度精炼效果硫分配系数真空感应炉感应电炉顶吹转炉脱硫效果脱氧剂除氧剂等离子

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

在有类型 1 自体免疫的肝炎的日本病人的尖锐表示的 Centrilobular 坏死

引用

World Journal of Hepatology 2012年第9期4卷 262-267页

作者： Kazumichi Abe Yukiko Kanno Ken Okai Fumiko Katsushima Kyoko Monoe Hironobu saito Atsushi Takahashi Junko Yokokawa Hiromasa Ohira Department of Gastroenterology and Rheumatology Fukushima Medical University School of Medicine1 HikarigaokaFukushima 960-1295Japan

AIM:To compare clinicopathological features of acute presentation of type 1 autoimmune hepatitis(AIH) with or without centrilobular necrosis(CN).METHODS:Our study comprised 41 patients with biopsy-proven acute presentation(acute exacerbation phase 36,acute hepatitis phase 5) of type 1 AIH at our hospital from 1975 to *** serum alanine aminotransferase(ALT)(> 5x upper limit of normal) identified acute presentation of the *** compared clinicopathological features of these AIH patients with or without *** data used for analysis included patient background(age,sex,type of disease,presence of complications with other autoimmune diseases,human leukocyte antigen,and International Autoimmune Hepatitis Group score),clinical parameters at presentation(ALT,alkaline phosphatase,IgG,anti-nuclear antibodies,and anti-smooth muscle antibodies),histology and ***:CN was found in 13(31.7%) patients with acute presentation(acute exacerbation phase 10,acute hepatitis phase 3) of *** IgG levels of patients with CN were significantly lower than those of patients without CN(mean:2307 mg/dL vs 3126 mg/dL,P < 0.05),while antinuclear antibody-negative rates were significantly higher(30.7%vs 3.5%,P < 0.05).However,other clinical features were similar between the two *** frequency of advanced fibrosis in patients with CN was significantly lower than in patients without CN(F0-2:84.6% vs 35.7%,F3-4:15.4% vs 64.3%,P < 0.05).Other histological features were similar between the two *** there was no significant difference between groups when evaluated using the revised original score(12 vs 14),the simplified AIH score of patients with CN was significantly lower(6 vs 7,P < 0.05).Frequency of DR4 was similar between patients with and without ***:CN is observed in both Japanese patients with acute hepatitis phase and acute exacerbation phase of type 1 AIH,although AIH with CN often shows clinical features of the genuine ac

关键词： Autoimmune hepatitis Centrilobular necrosis Acute presentation Acute exacerbation phase Acute hepatitis phase

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

正畸弹性分牙圈直立阻生下颌第二恒磨牙

引用

中国口腔医学继续教育杂志 2010年第3期13卷 17-19页

作者： Celia T. M. H. saito Alex Luiz Pozzobon Pereira Thais Varanda Sonia Regina Panzarini Pedro Felicio Estrada Bernabe 禹洁（译）姜若萍（审）不详北京大学口腔医学院正畸科北京海淀区中关村南大街22号100081

16岁女性患者．主诉下颌第二恒磨牙区反复发作的自发性疼痛，检查发现其病因为下颌第二恒磨牙前倾阻生。本文报告了一种简单的利用正畸弹性分牙圈直立阻生磨牙的方法。

关键词：阻生下颌磨牙正畸分牙圈

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

α1,2-岩藻糖转移酶基因转染增加卵巢癌细胞系RMG-Ⅰ Lewis y抗原的表达

引用

中国医学科学院学报 2008年第3期30卷 284-289页

作者：林蓓郝莹莹王冬冬朱连成张淑兰齐藤真木子岩森正男中国医科大学附属盛京医院妇产科沈阳110004 日本东京大学医学部小儿科日本东京113-8655 日本近畿大学理工学部化学科日本大阪577-8502

目的将人α1,2-岩藻糖基转移酶(α1,2-FT)基因转染卵巢癌细胞系RMG-Ⅰ并探讨细胞表面Lewisy及其他相关糖脂抗原的变化。方法采用PCR方法克隆人α1,2-FT基因编码区HFUT-H,构建表达载体pcDNA3.1(-)-HFUT-H,利用磷酸钙法将其转染入卵巢癌... 详细信息

目的将人α1,2-岩藻糖基转移酶(α1,2-FT)基因转染卵巢癌细胞系RMG-Ⅰ并探讨细胞表面Lewisy及其他相关糖脂抗原的变化。方法采用PCR方法克隆人α1,2-FT基因编码区HFUT-H,构建表达载体pcDNA3.1(-)-HFUT-H,利用磷酸钙法将其转染入卵巢癌细胞系RMG-Ⅰ,建立α1,2-FT基因稳定高表达细胞株RMG-Ⅰ-H。通过酶活性测定证明转染前后细胞系α1,2-FT活性的改变,采用薄层层析、薄层层析免疫染色方法测定转染前后细胞脂质及糖脂,特别是Ⅱ型寡糖的变化。结果基因转染后细胞RMG-Ⅰ-H中H-1抗原及Lewisy抗原显著增加,特别是Lewisy抗原为转染前的20倍;而Ⅰ型糖链Lewisb显著减少。转染前后细胞膜上的主要脂质成分胆固醇和磷脂质的含量没有变化,且中性糖脂质也没有明显变化。结论α1,2-FT基因转染增加α1,2-FT活性的同时,增加卵巢癌细胞系RMG-Ⅰ Lewisy抗原的表达;RMG-Ⅰ Lewisy高表达细胞系的建立为研究Lewisy抗原与卵巢癌生物学行为提供了细胞模型。

关键词：卵巢肿瘤 α1,2-岩藻糖基转移酶基因转染 Lewis抗原

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

水性FEVE氟碳树脂Lumiflon的开发和应用

引用

有机氟工业 2017年第1期 41-45页

作者：王舒钟高柳敬志斋藤俊钟毅旭硝子化工贸易(上海)有限公司上海200051 旭硝子化学品公司

FEVE氟碳树脂具有优异的长久耐候性,可以降低全寿命周期成本,减少排放。水性FEVE氟碳树脂有乳液型和分散型,分散型树脂可形成更致密的涂膜。各类水性树脂都可赋予自清洁性能。

关键词：超耐久长效涂料全寿命周期成本水性氟碳树脂自清洁型水性涂膜

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Electrolytic Production of NF3 Using Boron-Doped Diamond Anode in Molten NH4F·2HF

引用

Journal of Chemistry and Chemical Engineering 2012年第6期6卷 499-505页

作者： Akimasa Tasaka Yuki Iida Tomoyuki Shiono Masaharu Uno Yoshinori Nishiki Tsuneto Furuta Morihiro saito Minoru Inaba Department of Applied Chemistry Graduate School of Engineering Doshisha University Kyoto 610-0321 Japan Department of Molecular Chemistry and Biochemistry Faculty of Science and Engineering Doshisha University Kyoto 610-0321 Japan Permerec Electrode Ltd. Kanagawa 252-0826 Japan

The current efficiency for NF3 formation was independent on the current density in the range of 200 to 1,000 mA·cm-2. The average values of NF3 current efficiencies on the BDD (boron-doped diamond) anode with the boron-concentration of 2,500 ppm were 32.3% at 80°C, 63.3% at 100°C and 59.7% at 120°C. The best current efficiencies for NF3 formation on the BDD anode with boron-concentrations of 2,500, 5,000 and 7,500 ppm were obtained at 100°C and those were 63.3%, 73.3% and 56.2%, respectively. Although anode effect occurred on the BDD electrodes covered with a part of the surface of the spiculate structure, which had the boron-concentrations higher than 7,500 ppm, it did not take place on the BDD electrodes covered with the surface of diamond structure, even if the BDD electrode had the boron-concentration of 8,000 ppm.

关键词：掺硼金刚石 NF3 阳极液电解法生产 NH4F 金刚石结构电流效率 BDD

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Evaluation of the margins of differentiated early gastric cancer by using conventional endoscopy

引用

World Journal of Gastrointestinal Endoscopy 2015年第6期7卷 659-664页

作者： Shigetaka Yoshinaga Ichiro Oda Seiichiro Abe Satoru Nonaka Haruhisa Suzuki Hajime Takisawa Hirokazu Taniguchi Yutaka saito Endoscopy Division National Cancer Center Hospital Pathology Division National Cancer Center Hospital

AIM: To evaluate the determination of the margin of differentiated-type early gastric cancers by using conventional ***: We retrospectively evaluated 364 differentiated early gastric cancers that were endoscopically resected as en-bloc specimens and diagnosed pathologically in detail between November 2007 and October 2008. All procedures were done with conventional endoscopes and all endoscopic samples, before and after indigo carmine dye, were re-evaluated using a digital filing system by one endoscopist. We analyzed the incidence of lesions with unclear margins and the relationship between unclear margins and relevant clinicopathological findings. RESULTS: The rate of lesions with unclear margins was 20.6%(75/364). Multivariate regression analysis suggested that the factors that make the determination of the margin difficult were normal color, presence of components of flat area(0-IIb), a diameter ≥ 21 mm, ulceration, and components of poorly differentiated adenocarcinoma in the mucosal ***: As many as 20% of differentiated early gastric cancers show unclear margins. Consideration of the factors associated with unclear margins may help endoscopists to accurately determine the margins of the lesion.

关键词： Early gastric cancer Conventional endoscopy Determination of the margin

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Matrix metalloproteinase-2 as a superior biomarker for peritoneal deterioration in peritoneal dialysis

引用

World Journal of Nephrology 2016年第2期5卷 204-212页

作者： Ichiro Hirahara Eiji Kusano Yoshiyuki Morishita Makoto Inoue Tetsu Akimoto Osamu saito Shigeaki Muto Daisuke Nagata Division of Nephrology Department of Internal MedicineJichi Medical University

AIM: To investigate the efficacy of effluent biomarkers for peritoneal deterioration with functional decline in peritoneal dialysis(PD). METHODS: From January 2005 to March 2013, the subjects included 218 PD patients with end-stage renal disease at 18 centers. Matrix metalloproteinase-2(MMP-2), interleukin-6(IL-6), hyaluronan, and cancer antigen 125(CA125) in peritoneal effluent were quantified with enzyme-linked immunosorbent assay. Peritoneal solute transport rate was assessed by peritoneal equilibration test(PET) to estimate peritoneal deterioration. RESULTS: The ratio of the effluent level of creatinine(Cr) obtained 4 h after injection(D) to that of plasma was correlated with the effluent levels of MMP-2(ρ = 0.74, P < 0.001), IL-6(ρ = 0.46, P < 0.001), and hyaluronan(ρ = 0.27, P < 0.001), but not CA125(ρ = 0.13, P = 0.051). The area under receiver operating characteristic curve for the effluent levels of MMP-2, IL-6, and hyaluronan against high PET category were 0.90, 0.78, 0.62, and 0.51, respectively. No patient developed new-onset encapsulating peritoneal sclerosis for at least 1.5 years after peritoneal effluent ***: The effluent MMP-2 level most closely reflected peritoneal solute transport rate. MMP-2 can be a reliable indicator of peritoneal deterioration with functional decline.

关键词：透明质酸聚酯类化合物治疗方法临床分析

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

ALC-CH系统在水热处理过程中的物理化学变化—Ⅱ 水热处理时间的影响

引用

硅酸盐通报 1999年第4期18卷 22-27页

作者：潘志华杨南如冈田能彦高田みのり齐藤亨南京化工大学材料系日本秩父小野田(株)中央研究所

ＸＲＤ、ＴＧ－ＤＴＡ、ＩＲ和固体２９ＳｉＮＭＲ对ＡＬＣ废渣中添加氢氧化钙后的ＡＬＣ－ＣＨ混合物系统在水热处理过程中的物理化学变化进行了测定和分析。同时用ＢＥＴ方法测定了水热处理物的比表面积随水热处理时间的变化。结果表... 详细信息

ＸＲＤ、ＴＧ－ＤＴＡ、ＩＲ和固体２９ＳｉＮＭＲ对ＡＬＣ废渣中添加氢氧化钙后的ＡＬＣ－ＣＨ混合物系统在水热处理过程中的物理化学变化进行了测定和分析。同时用ＢＥＴ方法测定了水热处理物的比表面积随水热处理时间的变化。结果表明，ＡＬＣ废渣中添加适量氢氧化钙，经１８０℃下水热处理３～１６小时后均不同程度地形成了αＣ２ＳＨ，其形成量随水热处理时间的延长而增加。水热处理物具有较高的比表面积，于１２～２２ｍ２／ｇ之间，并且随水热处理时间的延长而减小。所以，适当延长水热处理时间将有利于αＣ２ＳＨ的形成，从而有利于以合成主含βＣ２Ｓ的贝利特水泥或高活性水泥混合材料为目的的后续煅烧过程。但是，过度延长水热处理时间不仅对增加α－Ｃ２ＳＨ的形成量作用不明显，而且会导致水热处理物比表面积的减小，影响最终烧成物的活性。

关键词： ALC 废渣水热处理物理化学废物处理混凝土

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：