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Investigation on the Novel High-performance Copper/Graphene Composite Conductor for High Power Density Motor

CES Transactions on Electrical Machines and Systems 2024年第1期8卷 80-85页

作者： Jiaxiao Wang tingting zuo Jiangli Xue Yadong Ru Yue Wu Zhuang Xu Yongsheng Liu Zhaoshun Gao Puqi Ning Tao Fan Xuhui Wen Li Han Liye Xiao Shanghai University of Electric Power Shanghai 200090Chinaand the Institute of Electrical EngineeringChinese Academy of SciencesShanghai 200090China the Institute of Electrical Engineering Chinese Academy of SciencesBeijing 100190China with Shanghai University of Electric Power Shanghai 200090China

High-performance Cu/Graphene composite wire synergistically strengthened by nano Cr_(3)C_(2) phase was directly synthesized via hot press sintering followed by severe cold plastic deformation, using liquid paraffin and CuCr alloy powder as the raw materials. Since graphene is in situ formed under the catalysis of copper powder during the sintering process, the problem that graphene is easy to agglomerate and difficult to disperse uniformly in the copper matrix has been solved. The nano Cr_(3)C_(2)-particles nailed at the interface favor to improve the interface bonding. The Cu/Graphene composite possesses high electrical conductivity, hardness, and plasticity. The composite wire exhibits high electrical conductivity of 96.93% IACS, great tensile strength of 488MPa, and excellent resistance to softening. Even after annealing at 400℃ for 1 h, the tensile strength can still reach 268 MPa with a conductivity of about 99.14% IACS.The wire's temperature coefficient of resistance(TCR) is largely reduced to 0.0035/℃ due to the complex structure,which leads the wire to present low resistivity at higher temperatures. Such Cu/Graphene composite wire with excellent comprehensive performance has a good application prospect in high-power density motors.

关键词： Cu/Graphene composite Mechanical properties Electrical property Microstructure Temperature coefficient of resistance

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Effect of Plastic Deformation on Microstructure and Properties of Cu-(1 wt%-6 wt%) Ag Alloy

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Journal of Wuhan University of Technology(Materials Science) 2024年第3期39卷 747-753页

作者：茹亚东 ZHANG Zhongyuan 高召顺 ZHANG Ling zuo tingting XUE Jiangli TANG Zhixiang DA Bo LIU Yongsheng XIAO Liye Institute of Electrical Engineering Chinese Academy of SciencesBeijing 100190China Department of Physics Shanghai University of Electric PowerShanghai 201306China University of Chinese Academy of Sciences Beijing 100190China International Joint Labora-tory for Light Alloys(MOE) College of Materials Science and EngineeringChongqing UniversityChongqing 400044China Research and Services Division of Materials Data and Integrated System National Institute for Materials ScienceTsukuba 305-0047Japan

In the present study,the Cu-(1 wt%-6 wt%)Ag alloys were prepared by melting,forging and wire drawing.The effects of plastic deformation on microstructure evolution and properties of the alloys were investigated.The results show that non-equilibrium eutectic colonies exist in the Cu-(3 wt%-6 wt%)Ag alloy and no eutectic colonies in the 1 wt%-2 wt%Ag containing alloys.These eutectic colonies are aligned along the drawing direction and refined with the increase of draw ratio.Attributed to the refinement of eutectic colonies,the Cu-Ag alloy exhibits higher strength with the increase of draw ratio.The Cu-6Ag alloy exhibits excellent comprehensive properties with a strength of 930 MPa and a conductivity of 82%IACS when the draw ratio reaches 5.7.

关键词： Cu-Ag alloy high strength and high conductivity microstructure eutectic structure strengthening mechanism

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National cancer incidence and mortality in China, 2012

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Chinese Journal of Cancer Research 2016年第1期28卷 1-11页

作者： Wanqing Chen Rongshou Zheng tingting zuo Hongmei Zeng Siwei Zhang Jie He Cancer Hospital Chinese Academy of Medical Sciences Peking Union Medical College & National Cancer Center Beijing 100021 China

Background： Population-based cancer registration data in 2012 from all available cancer registries were collected by the National Central Cancer Registry （NCCR）. NCCR estimated the numbers of new cancer cases and cancer deaths in China with compiled cancer incidence and mortality rates. Methods： In 2015, there were 261 cancer registries submitted cancer incidence and deaths occurred in 2012. All the data were checked and evaluated based on the NCCR criteria of data quality. Qualified data from 193 registries were used for cancer statistics analysis as national estimation. The pooled data were stratified by area （urban/rural）, gender, age group [0, 1-4, 5-9, 10-14, ..., 85＋] and cancer type. New cancer cases and deaths were estimated using age-specific rates and corresponding national population in 2012. The Chinese census data in 2000 and Segi＇s population were applied for age-standardized rates. All the rates were expressed per 100,000 person-year. Results： Qualified 193 cancer registries （74 urban and 119 rural registries） covered 198,060,406 populations （100,450,109 in urban and 97,610,297 in rural areas）. The percentage of cases morphologically verified （NIV%） and death certificate-only cases （DCO%） were 69.13% and 2.38%, respectively, and the mortality to incidence rate ratio （M/I） was 0.62. A total of 3,586,200 new cancer cases and 2,186,600 cancer deaths were estimated in China in 2012. The incidence rate was 264.85/100,000 （289.30/100,000 in males, 239.15/100,000 in females）, the age-standardized incidence rates by Chinese standard population （ASIRC） and by world standard population （ASIRW） were 191.89/100,000 and 187.83/100,000 with the cumulative incidence rate （0-74 age years old） of 21.82%. The cancer incidence, ASIRC and ASIRW in urban areas were 277.17/100,000, 195.56/100,000 and 190.88/100,000 compared to 251.20/100,000, 187.10/100,000 and 183.91/100,000 in rural areas, respectively. The cancer mortality was 161.49/ 100,000 （ 198.99/100,000 in males, 122.06/ 100,000 in females）, the age-standardize

关键词： Cancer registry incidence mortality epidemiology China

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Cancer incidence and mortality in China in 2013：an analysis based on urbanization level

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Chinese Journal of Cancer Research 2017年第1期29卷 1-10页

作者： Wanqing Chen Rongshou Zheng Siwei Zhang Hongmei Zeng tingting zuo Changfa Xia Zhixun Yang Jie He National Central Cancer Registry National Cancer Center/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100021 China

Objective： To explore the cancer patterns in areas with different urbanization rates（URR） in China with data from 255 population-based cancer registries in 2013, collected by the National Central Cancer Registry（NCCR）.Methods： There were 347 cancer registries submitted cancer incidence and deaths occurred in 2013 to NCCR.All those data were checked and evaluated based on the NCCR criteria of data quality, and qualified data from 255 registries were used for this analysis. According to the proportion of non-agricultural population, we divided cities/counties into 3 levels： high level, with URR equal to 70% and higher; median level, with URR between 30%and 70%; and low level, with URR equal to 30% and less. Cancer incidences and mortalities were calculated,stratified by gender and age groups in different areas. The national population of Fifth Census in 2000 and Segi＇s population were applied for age-standardized rates.Results： Qualified 255 cancer registries covered 226,494,490 populations. The percentage of cases morphologically verified（MV%） and death certificate-only cases（DCO%） were 68.04% and 1.74%, respectively,and the mortality to incidence rate ratio（M/I） was 0.62. A total of 644,487 new cancer cases and 399,275 cancer deaths from the 255 cancer registries were submitted to NCCR in 2013. The incidence rate was 284.55/100,000（314.06/100,000 in males, 254.19/100,000 in females）, and the age-standardized incidence rates by Chinese standard population（ASIRC） and by world standard population（ASIRW） were 190.10/100,000 and 186.24/100,000 with the cumulative incidence rate（0–74 age years old） of 21.60%. The cancer mortality was 176.28/100,000（219.03/100,000 in males, 132.30/100,000 in females）, and the age-standardized mortality rates by Chinese standard population（ASMRC） and by world standard population（ASMRW） were 110.91/100,000 and 109.92/100,000, and the cumulative mortality rate（0–74 age years old） was 12.43%. Low urbanization areas were high in crude cancer incidence and mortality rates, middle urbanization

关键词： Cancer incidence mortality epidemiology urbanization China

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Epidemiology and trend analysis on malignant mesothelioma in China

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Chinese Journal of Cancer Research 2017年第4期29卷 361-368页

作者： Jun Zhao tingting zuo Rongshou Zheng Siwei Zhang Hongmei Zeng Changfa Xia Zhixun Yang Wanqing Chen National Cancer Center/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College

Objective： Population-based cancer registration data were used to analyze the epidemiology and trend of malignant mesothelioma in China, and the result would provide basic data for its prevention and control. Methods： Malignant mesothelioma data in 2013 were retrieved from the database of National Cancer Registry. Malignant mesothelioma incidence and mortality were estimated using age-specific rate by urban/rural and gender according to the national population in 2013. Malignant mesothelioma data from 22 cancer registries were used for trend analysis during 2000-2013. Results： It is estimated that there were 2,041 new malignant mesothelioma cases and 1,659 malignant mesothelioma deaths occurred in 2013. The crude incidence rate in China were 1.50/106 （males 1.67/106, females 1.32/106）, age-standardized incidence rates by Chinese standard population （ASIRC） and by world standard population （ASIRW） were 1.03/106 and 1.02/106, respectively. The crude mortality rate in China was 1.22/106 （males 1.67/106, females 1.32/106）, age-standardized mortality rates by Chinese standard population （ASMRC） and by world standard population （ASMRW） were 0.83/106 and 0.81/106, respectively. There was an increasing trend of incidence rate for malignant mesothelioma in registration areas of China during 2000-2013 with annual percentage change （APC） of 2.5% [95% confidence interval （95% CI）： 0.6%--4.5%]. After age standardization, no significant differences were observed. No matter for crude mortality rates or age-standardized mortality rates, no significant differences were observed during 2000-2013. Conclusions： Malignant mesothelioma is the major occupational and environmental neoplasm associated with asbestos exposure. The increasing incidence trend suggests that more attention should be paid on this disease.

关键词： Malignant mesothelioma incidence mortality trend cancer registry

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中医药院校护理本科生实习前突发公共卫生事件应急能力现状调查

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中国中医药现代远程教育 2024年第5期22卷 187-189页

作者：左婷婷沙晓华南昌医学院妇幼保健与美容医学院江西南昌330008

目的了解新型冠状病毒肺炎疫情突发公共卫生事件下护生实习前的应急能力现状及影响因素,为提升南昌医学院护生实习前的应急能力提供依据。方法以南昌医学院2017级护理专业学生249名为样本,使用突发公共卫生事件应急能力量表在其实习... 详细信息

目的了解新型冠状病毒肺炎疫情突发公共卫生事件下护生实习前的应急能力现状及影响因素,为提升南昌医学院护生实习前的应急能力提供依据。方法以南昌医学院2017级护理专业学生249名为样本,使用突发公共卫生事件应急能力量表在其实习前进行问卷调查。结果护生实习前突发公共卫生事件应急能力总平均分为(3.31±0.22)分,处于中等水平,其中急救能力(3.48±0.20)分,得分最高,应急知识(3.04±0.24)分,得分最低。参加过培训和参加过志愿服务是应急能力的主要影响因素(P<0.01)。结论护理本科生实习前的突发公共卫生事件应急能力有待于进一步提高。学校应重视护理本科生突发公共卫生事件的教育工作,在实践中,应根据具体问题,采用不同的教学方式,提高护理本科生突发公共卫生事件应急能力。

关键词：实习前护理本科生突发公共卫生事件应急能力

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The influence of stage at diagnosis and molecular subtype on breast cancer patient survival: a hospital.based multi.center study

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Chinese Journal of Cancer 2017年第11期36卷 647-656页

作者： tingting zuo Hongmei Zeng Huichao Li Shuo Liu Lei Yang Changfa Xia Rongshou Zheng Fei Ma Lifang Liu Ning Wang Lixue Xuan Wanqing Chen National Office for Cancer Prevention and Control & National Central Cancer Registry National Cancer Center/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100021 P. R.China Key Laboratory of Carcinogenesis and Translation Research (Ministry of Education/Beijing) Beijing Office for Cancer Prevention and Control Peking University Cancer Hospital & Institute Beijing 100142 P. R. China Department of Medical Oncology National Cancer Center/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100021 P. R. China Department of Statistics The European Organization for Research and Treatment of Cancer (EORTC) 111200 Brussels Belgium Department of Breast Surgery National Cancer Center/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100021 P. R. China

Background: Stage at diagnosis and molecular subtype are important clinical factors associated with breast cancer patient survival. However, subgroup survival data from a large study sample are limited in China.To estimate the survival differences among patients with different stages and various subtypes of breast cancer, we conducted a hospital-based multi-center study on breast cancer in Beijing, China.Methods: All resident patients diagnosed with primary, invasive breast cancer between January 1,2006 and December 31,2010 from four selected hospitals in Beijing were included and followed up until December 31,2015. Hospitalbased data of stage at diagnosis, hormone receptor status, and selected clinical characteristics, including body mass index(BMI), menopausal status, histological grade, and histological type, were collected from the medical records of the study subjects. Overall survival(OS) and cancer-specific survival(CSS) were estimated. Cox proportional hazards models were employed to evaluate the associations of stage at diagnosis and molecular subtype with patient survival.Results: The 5-year OS and CSS rates for all patients were 89.4% and 90.3%. Survival varied by stage and molecular subtype. The 5-year OS rates for patients with stage I, Ⅱ, Ⅲ, and IV diseases were 96.5%, 91.6%, 74.8%, and 40.7%,respectively, and the corresponding estimates of 5-year CSS rates were 97.1%, 92.6%, 75.6%, and 42.7%, respectively.The 5-year OS rates for patients with luminal A, luminal B, HER2, and triple-negative subtypes of breast cancer were92.6%, 88.4%, 83.6%, and 82.9%, respectively, and the corresponding estimates of 5-year CSS rates were 93.2%, 89.1 %,85.4%, and 83.5%, respectively. Multivariate analysis showed that stage at diagnosis and molecular subtype were important prognostic factors for breast cancer.Conclusions: Survival of breast cancer patients varied significantly by stage and molecular subtype. Cancer screening is encouraged for the early detection and early diagnosis of breast cancer. More advanced ther

关键词： Breast cancer Stage Molecular subtype Survival China

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LaB_(6)阴极的制备、应用与展望

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电子显微学报 2024年第2期43卷 240-250页

作者：徐跃凡茹亚东左婷婷伍岳王鹏飞刘俊标高召顺韩立肖立业中国科学院电工研究所北京100190 中国科学院大学北京100049

六硼化镧(LaB_(6))阴极作为一种优异的热发射电子源,应用领域广泛,是高端电子束仪器及设备的关键元器件。本文系统介绍了LaB_(6)材料的制备和加工方法、阴极常见的装卡方式,总结了其在各领域应用现状,并对其发展前景进行了展望。

关键词： LaB_(6) 单晶阴极器件电子束设备

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诊断分期和分子分型对乳腺癌患者生存的影响:一项基于医院的多中心研究

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癌症 2018年第3期37卷 99-109页

作者： tingting zuo Hongmei Zeng Huichao Li Shuo Liu Lei Yang Changfa Xia Rongshou Zheng Fei Ma Lifang Liu Ning Wang Lixue Xuan Wanqing Chen 全国肿瘤防治研究办公室全国肿瘤登记中心国家癌症中心/肿瘤医院中国医学科学院北京协和医学院北京100021 恶性肿瘤发病机制及转化研究重点实验室(教育部/北京) 北京市肿瘤防治研究所北京大学肿瘤医院/研究所北京100142 肿瘤科国家癌症中心/肿瘤医院中国医学科学院北京协和医学院北京100021 统计系欧洲癌症研究和治疗组织比利时布鲁塞尔111200 乳腺外科国家癌症中心/肿瘤医院中国医学科学院北京协和医学院北京100021

背景与目的诊断分期和分子分型是与乳腺癌患者生存相关的重要临床因素。然而,在中国从大型研究样本中获取的亚组生存数据是有限的。为了评估不同分期和各种分型乳腺癌患者的生存差异,我们在中国北京进行了一项以医院为基础的多中心乳腺... 详细信息

背景与目的诊断分期和分子分型是与乳腺癌患者生存相关的重要临床因素。然而,在中国从大型研究样本中获取的亚组生存数据是有限的。为了评估不同分期和各种分型乳腺癌患者的生存差异,我们在中国北京进行了一项以医院为基础的多中心乳腺癌研究。方法 2006年1月1日至2010年12月31日期间,在北京的4家医院被诊断为原发浸润性乳腺癌的住院患者均被纳入本研究,并随访至2015年12月31日。从患者的病例中收集基于医院的患者的诊断分期、激素受体状态和选定的临床特征,包括体质指数(body mass index,BMI)、绝经状态、组织学分级和组织学类型的数据。估算总生存率(overall survival,OS)和癌症特异性生存率(cancer-specific survival,CSS)。采用Cox比例风险模型评估诊断分期和分子分型与患者生存的关系。结果全部患者的5年OS和CSS分别为89.4%和90.3%。癌患者的生存率因分期和分子分型不同而各异。Ⅰ、Ⅱ、Ⅲ和Ⅳ期患者的5年OS分别为96.5%、91.6%、74.8%和40.7%,相应的5年CSS分别为97.1%、92.6%、75.6%和42.7%。Luminal A、Luminal B、HER2和三阴性乳腺癌患者的5年OS分别为92.6%、88.4%、83.6%和82.9%,相应的5年CSS分别为93.2%、89.1%、85.4%和83.5%。多因素分析显示,诊断分期和分子分型是影响乳腺癌患者预后的重要因素。结论乳腺癌患者的生存率因分期和分子分型差异而显著不同。鼓励妇女通过乳腺癌筛查早期发现并早期诊断癌症病例。HER2和三阴性亚型乳腺癌患者需要更先进的治疗方法和保健政策。

关键词：乳腺癌分期分子分型生存率中国

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肺受累抗中性粒细胞胞质抗体相关性血管炎的临床特征及危险因素分析

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中国呼吸与危重监护杂志 2023年第2期22卷 96-103页

作者：左婷婷陈延斌苏州大学附属第一医院呼吸与危重症医学科江苏苏州215000 南京医科大学附属无锡人民医院呼吸与危重症医学科江苏无锡214000

目的探讨肺受累抗中性粒细胞胞质抗体相关性血管炎(antineutrophil cytoplasmic antibodyassociated vasculitis,AAV)的临床特征及其相关危险因素。方法回顾性分析2015年1月—2020年12月苏州大学附属第一医院收治的113例肺受累AAV患者... 详细信息

目的探讨肺受累抗中性粒细胞胞质抗体相关性血管炎(antineutrophil cytoplasmic antibodyassociated vasculitis,AAV)的临床特征及其相关危险因素。方法回顾性分析2015年1月—2020年12月苏州大学附属第一医院收治的113例肺受累AAV患者的临床资料,比较不同类型AAV累及肺脏时的一般特征、治疗及预后情况。并与69例肺未受累的AAV进行对比分析,比较两组患者的临床特点、生存差异以及相关危险因素。结果113例肺受累AAV患者中,男57例,女56例,平均发病年龄(67±11)岁。其中显微镜下多血管炎(microscopic polyangiitis,MPA)86例,肉芽肿性多血管炎(granulomatosis polyangiitis,GPA)21例,嗜酸性肉芽肿性多血管炎(eosinophilia granulomatosis polyangiitis,EGPA)6例,三者在发病年龄及性别分布上无明显差异。肺受累AAV最常见的临床症状为咳嗽、咳痰、胸闷,部分患者以咯血为首发症状,均无特异性。在影像学方面,MPA以肺间质性改变最常见,GPA多表现为双肺多发结节或肿块影,部分可见空洞样改变;EGPA的影像学虽未见明显特征性,但其鼻窦炎的发病率较其他类型明显升高;73例患者合并肺外受累,最常见的受累脏器为肾脏,其次是心血管和神经系统。与肺未受累组相比,肺受累组在伯明翰血管炎活动评分(Birmingham vasculitis activity score,BVAS)≥15分、高抗中性粒细胞胞质抗体滴度、补体C3或C4降低、肺部感染、采用机械通气和(或)血浆置换等辅助治疗方面的患者比例明显高于肺未受累组(P<0.05)。40例患者在随访期间死亡,肺脏受累是AAV患者病死率增加的危险因素。将肺受累AAV分为死亡组和存活组,死亡组合并冠心病、多脏器受累(n≥3)、BVAS≥15分、血肌酐≥500μmol/L、血红蛋白≤90 g/L、C反应蛋白≥10 mg/L、肺部感染、需要机械通气和(或)血浆置换等辅助治疗的患者比例较存活组明显升高(P<0.05)。结论肺受累AAV好发于老年人,男女发病率相仿,临床表现无特异性,影像学以肺间质性改变和双肺多发结节或肿块影为主,常同时合并多脏器受累;BVAS≥15分是AAV发生肺受累的独立危险因素;肺受累AAV预后相对较差,合并冠心病、肺部感染和C反应蛋白≥10 mg/L是预后不良的独立危险因素。

关键词：抗中性粒细胞胞质抗体血管炎肺临床特征危险因素

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