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2021—2023年某三甲医院ICU病原菌分布及耐药性分析

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中国社区医师 2024年第10期40卷 17-19页

作者：骆霜尤婷婷柳州市柳铁中心医院广西壮族自治区柳州545007

目的:分析2021—2023年某三甲医院ICU病原菌分布及耐药性。方法:选取柳州市柳铁中心医院2021—2023年ICU各类送检标本中分离的1 581株病原菌作为研究资料,均行菌株鉴定和药敏试验。统计1 581株病原菌标本来源、类型、耐药性。结果:1 58... 详细信息

目的:分析2021—2023年某三甲医院ICU病原菌分布及耐药性。方法:选取柳州市柳铁中心医院2021—2023年ICU各类送检标本中分离的1 581株病原菌作为研究资料,均行菌株鉴定和药敏试验。统计1 581株病原菌标本来源、类型、耐药性。结果:1 581株病原菌主要分离自下呼吸道标本,共分离1 195株(75.6%),类型主要是革兰阴性菌[1 200株(75.9%)],其次是革兰阳性菌[258株(16.3%)]和真菌[123株(7.8%)]。革兰阴性菌中,以鲍曼不动杆菌为主;革兰阳性菌中,以金黄色葡萄球菌为主。鲍曼不动杆菌对替加环素敏感性较高,敏感率>80%。对头孢类、β-内酰胺酶抑制剂类、碳青霉烯类、氨基糖苷类药物的耐药率均>80%。金黄色葡萄球菌对青霉素G耐药率>95%,对利奈唑胺、万古霉素、替考拉宁、替加环素和头孢洛林的耐药率均为0。结论:2021—2023年该院ICU病原菌感染以呼吸道感染为主,类型主要是革兰阴性菌,临床可对病原菌耐药性的变化进行实时监测,合理选用抗生素的同时控制和减少院内感染。

关键词： ICU 病原菌耐药性

全媒体时代高校红色文化的传播现状及策略研究--以井冈山为例

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文化创新比较研究 2024年第1期8卷 68-71页

作者：肖楠尤亭亭樊玉华青岛科技大学高分子科学与工程学院山东青岛266590 山东科技大学机械电子工程学院山东青岛266590

习近平总书记在党的二十大报告中对文化自信自强提出新的要求,“全面建设社会主义现代化国家,必须坚持中国特色社会主义发展道路,增强文化自信,围绕举旗帜、聚民心、育新人、兴文化、展形象建设社会主义文化强国”。红色文化作为中国文... 详细信息

习近平总书记在党的二十大报告中对文化自信自强提出新的要求,“全面建设社会主义现代化国家,必须坚持中国特色社会主义发展道路,增强文化自信,围绕举旗帜、聚民心、育新人、兴文化、展形象建设社会主义文化强国”。红色文化作为中国文化的重要组成部分,如何在全媒体背景下提高高校传播效果,提升当代大学生对红色文化的认同感,是亟待研究的重要课题。该文以井冈山红色精神为例,在梳理原有传播途径的基础之上,深入井冈山开展现状调研,剖析在高校思政课中红色文化传播受阻的主要原因,根据当前全媒体时代特征提出红色文化传播的新模式,加强全媒体传播体系建设,推动高校思政教育课程改革,从而实现红色文化在高校的有效传播。

关键词：文化自信自强红色精神全媒体时代文化传播体系社会主义核心价值观思政教育课程改革

新质生产力推进乡村振兴战略的理论逻辑与发展路径

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对外经贸 2024年第4期 61-64,97页

作者：章刘成常纪锋尤婷婷哈尔滨商业大学黑龙江哈尔滨150028

基于乡村振兴的战略背景,针对城乡之间的发展不平衡以及农村发展不充分的问题,深入探究新质生产力如何推进乡村振兴的理论逻辑和发展路径。通过分析新质生产力的核心特征,包括创新驱动、绿色发展和信息化支撑,揭示新质生产力如何引领农... 详细信息

基于乡村振兴的战略背景,针对城乡之间的发展不平衡以及农村发展不充分的问题,深入探究新质生产力如何推进乡村振兴的理论逻辑和发展路径。通过分析新质生产力的核心特征,包括创新驱动、绿色发展和信息化支撑,揭示新质生产力如何引领农业产业升级、优化乡村人才结构,并解决乡村振兴中的资金和技术问题。研究结果表明,新质生产力通过促进农业技术进步、提升人才素质和优化资源配置,为乡村振兴提供了强大的动力。力图推进乡村振兴理论与实践的深化,有助于促进农业农村现代化和共同富裕的实现。

关键词：乡村振兴新质生产力农村现代化共同富裕

Multispectral Plasmon of Anisotropic Core-shell Gold Nanorods@SiO2： Dual-band Absorption Enhancement with Coupling Dye Molecules

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Chemical Research in Chinese Universities 2018年第5期34卷 772-780页

作者： CHE Yuping WANG Yang you tingting CHANG Huaiqiu YIN Penggang ZHAI Jin Key Laboratory of Bio-inspired Smart Interfacial Science and Technology Ministry of Educate'on Beijing Key Laboratory of Bio-inspired Energy Materials and Devices School of Chemistry Beihang University Beijing 100191 R R. China Institute of Chemistry Chinese Academy of Sciences Beijing 100190 P. R. China National Center for Nanoscience and Technology Beijing 100190 P. R. China

Direct evidence of effects of surface plasmon resonance（SPR） of gold naaorods（GNRs） on dual-band light absorption enhancement with coupling dye molecules was reported by introducing gold nanorod@SiO2（GNR@SiO2） core-shell nanoparticles into a photoelectric conversion system. GNR with asymmetric shape had unusual anisotropic SPR[transversal surface plasmon resonance（TSPR） and longitudinal surface plasmon resonance（LSPR）]. The excel- lent SPR of GNR made it a promising candidate as enhancing light absorption material to increase power conversion efflciency（PCE）. The PCE was improved nearly 17.2% upon incorporating GNRs, mostly due to the increase in Jsc, while Vo~ and FF were unchanged. The improvement was mostly contributed by the SPR of the GNRs with coupling of N719. And there was also a complementary to N719 in visible light range. Therefore, SPR is an effective tool in improving the photocurrent and consequently enhancement of PCE. The TSPR and LSPR effects of GNRs on light harvesting were reflected in the increased monochromatic incident photon-to-electron conversion efficiency（IPCE）. We also utilized finite-difference tirne-domain（FDTD） to investigate the light coupling of GNRs with TiO2. Compare to the base anode, the IPCE of optimized electrode showed significant improvement and peaks broadening at 500--600 nm and 610--710 nm. We got an increase in overall conversion efficiency from 6.4% to 7.5%.

关键词： Gold nanorod Plasmon Dual-band absorption Dye-sensitized solar cell(DSSC) N719

数智时代高校教学实验室安全管理现状分析与展望

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实验室科学 2024年第4期27卷 204-209页

作者：王繁章刘成尤婷婷李万涛教育部高等教育司课程教材与实验室处北京100816 哈尔滨商业大学教学实验设备管理中心黑龙江哈尔滨150228

当前,随着教育数字化战略行动深入推进,高等教育迫切需要进行深层次变革。高校教学实验室作为安全监管的重要领域,应探索运用数智技术在安全责任体系构建、实验项目风险评估、安全队伍建设、安全知识培训、安全设施配备等方面进行变革升... 详细信息

当前,随着教育数字化战略行动深入推进,高等教育迫切需要进行深层次变革。高校教学实验室作为安全监管的重要领域,应探索运用数智技术在安全责任体系构建、实验项目风险评估、安全队伍建设、安全知识培训、安全设施配备等方面进行变革升级,塑造“智能+”安全管理新生态。在调研高校教学实验室安全管理现状的基础上,分析了部分高校运用数智技术加强安全管理的实践案例,并对数智技术未来在实验室安全管理方面的研究和发展趋势进行了展望,如人工智能技术深度新应用、实验室安全管理运行新体制、AI for Science赋能带来的技术安全新风险、数字伦理与隐私问题等。

关键词：数智技术教学实验室安全管理

药学专业知识(二)指导课程的网络教学及实施情况分析

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中国高等医学教育 2024年第2期 64-66页

作者：周乐汤南付晖尤婷婷徐道华广东医科大学药学院广东东莞523808

目的:对药学专业知识(二)指导课程进行网络教学,评价该课程设置的合理性和教学效果。方法:利用学习通平台进行网络教学,统计和分析任务点、作业、课堂活动等完成情况。结果:学生全部完成42个任务点。测验平均成绩为91.26分,作业平均成绩... 详细信息

目的:对药学专业知识(二)指导课程进行网络教学,评价该课程设置的合理性和教学效果。方法:利用学习通平台进行网络教学,统计和分析任务点、作业、课堂活动等完成情况。结果:学生全部完成42个任务点。测验平均成绩为91.26分,作业平均成绩为90.34分。同步课堂签到率达到96%以上。随堂练习中位数成绩为90分。结论:该课程网络教学设置合理,学生完成情况较好,掌握了主要知识,教学效果满意。

关键词：网络教学药学专业知识(二) 课程设置实施情况

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Humidity-responsive nanocomposite of gold nanoparticles and polyacrylamide brushes grafted on Ag film: synthesis and application as plasmonic nanosensor

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Science China Materials 2018年第9期61卷 1201-1208页

作者： Huaxiang Chen tingting you Geng Xu Yukun Gao Chenmeng Zhang Nan Yang Penggang Yin Key Laboratory of Bio-inspired Smart Interfacial Science and Technology of Ministry of Education School of ChemistryBeihang UniversityBeijing 100191China

A general stepwise strategy for the preparation of new humidity-responsive plasmonic nanosensor was described for the first time, based on Ag film functionalization by polyacrylamide（PAAM） brushes via surface-initiated atom transfer radical polymerization（SI-ATRP） method and then assembled with gold nanoparticles（Au NPs）. We designed by this way a new plasmonic device made of Au NPs embedded in a humid vapor responsive polymer layer on Ag film and extensively characterized by surface-enhanced Raman scattering（SERS）. When the relative humidity（RH） is above 50%, the number of plasmonic hotspots decreases, causing SERS signal reduced noticeably, for the volume expansion of PAAM brushes varied the nano-gap between closely spaced Au NPs, and between Au NPs and Ag film. The reversible optical properties of the prepared nanocomposite tuned by RH were probed through SERS using 4-mercaptopyridine（4-Mpy） as a molecular probe, and the decrease of the RH reversibly induces a significant enhancement of the 4-Mpy SERS signal. By means of the high reversibility, the RH responsive nanocomposite developed in this paper provides a dynamic SERS platform and can be applied as plasmonic nanosensor which is proved to be stable for at least two months.

关键词： RH-response plasmonic nanosensor SERS

Estimation of economic burden throughout course of cervical squamous intraepithelial lesion and cervical cancer in China:A nationwide multicenter cross-sectional study

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Chinese Journal of Cancer Research 2023年第6期35卷 675-685页

作者： Hao Chen Xuelian Zhao Shangying Hu tingting you Changfa Xia Meng Gao Mingjie Dong youlin Qiao Fanghui Zhao Department of Cancer Epidemiology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Office of Cancer Screening National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China School of Population Medicine and Public Health Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Center for Global Health School of Population Medicine and Public HealthChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China

Objective: Cervical squamous intraepithelial lesion(SIL) and cervical cancer are major threats to females' health and life in China, and we aimed to estimate the economic burden associated with their diagnosis and ***: A nationwide multicenter, cross-sectional, hospital-based survey was conducted in 26 qualified hospitals across seven administrative regions of China. We investigated females who had been pathologically diagnosed with SIL and cervical cancer, and included five disease courses(“diagnosis”, “initial treatment”,“chemoradiotherapy”, “follow-up” and “recurrence/progression/metastasis”) to estimate the total costs. The median and interquartile range(IQR) of total costs(including direct medical, direct non-medical, and indirect costs), reimbursement rate by medical insurance, and catastrophic health expenditures in every clinical stage were ***: A total of 3,471 patients in different clinical stages were analyzed, including low-grade SIL(LSIL)(n=549), high-grade SIL(HSIL)(n=803), cervical cancer stage ⅠA(n=226), ⅠB(n=610), ⅡA(n=487), ⅡB(n=282), Ⅲ(n=452) and Ⅳ(n=62). In urban areas, the estimated total costs of LSIL and HSIL were $1,637.7(IQR:$956.4-$2,669.2) and $2,467.1(IQR:$1,579.1-$3,762.3), while in rural areas the costs were $459.0(IQR:$167.7-$1,330.3) and $1,230.5(IQR:$560.6-$2,104.5), respectively. For patients with cervical cancer stage ⅠA,ⅠB, ⅡA, ⅡB, and Ⅲ-Ⅳ, the total costs were $15,034.9(IQR:$11,083.4-$21,632.4), $19,438.6(IQR:$14,060.0-$26,505.9), $22,968.8(IQR:$16,068.8-$34,615.9), $26,936.0(IQR:$18,176.6-$41,386.0) and $27,332.6(IQR:$17,538.7-$44,897.0), respectively. Medical insurance covered 43%-55% of direct medical costs for cervical cancer patients, while the coverage for SIL patients was 19%-43%. For most cervical cancer patients, the expense was catastrophic, and the extent of catastrophic health expenditure was about twice large for rural patients than that for urban patients in each ***: The e

关键词： Squamous intraepithelial lesion cervical cancer economic burden medicare catastrophic health expenditures

Interface electronic engineering of molybdenum sulfide/MXene hybrids for highly efficient biomimetic sensors

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Nano Research 2023年第1期16卷 1158-1164页

作者： Pengfei Wu tingting you Qingyuan Ren Hongyan Xi Qingqing Liu Fengjuan Qin Hongfei Gu Yu Wang Wensheng Yan Yukun Gao Wenxing Chen Penggang Yin Key Laboratory of Bio-inspired Smart Interfacial Science and Technology of Ministry of Education School of ChemistryBeihang UniversityBeijing 100191China Energy&Catalysis Center School of Materials Science and EngineeringBeijing Institute of TechnologyBeijing 100081China Shanghai Synchrotron Radiation Facility Zhangjiang LaboratoryShanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201204China National Synchrotron Radiation Laboratory University of Science and Technology of ChinaHefei 230029China

Interface regulation plays a key role in the electrochemical performance for *** controlling the interfacial interaction,the electronic structure of active species can be adjusted effectively at micro and nano-level,which results in the optimal reaction energy ***,we propose an interface electronic engineering scheme to design a strongly coupled 1T phase molybdenum sulfide(1T-MoS2)/MXene hybrids for constructing an efficient electrocatalytic biomimetic *** local electronic and atomic structures of the 1T-MoS2/Ti3C2TX are comprehensively studied by synchrotron radiation-based X-ray photoelectron spectroscopy(XPS),as well as X-ray absorption spectroscopy(XAS)at atomic *** and theoretical calculations show that there are interfacial stresses,atomic defects and adjustable bond-length between MoS2/MXene nanosheets,which can significantly promote biomolecular adsorption and rapid electron transfer to achieve excellent electrochemical activity and reaction *** 1T-MoS2/Ti3C2TX modified electrode shows ultra high sensitivity of 1.198μA/μM for dopamine detection with low limit of 0.05μ*** anticipate that the interface electronic engineering investigation could provide a basic idea for guiding the exploration of advanced biosensors with high sensitivity and low detection limit.

关键词： MXene molybdenum sulfide interface electronic effect biomimetic sensor X-ray absorption spectroscopy