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Nano-Micro Letters 2025年第3期17卷 280-296页

作者： Chaoran Zhang Yichuan Gu Qu Jiang Ziyang Sheng Ruohan Feng Sihong Wang Haoyue Zhang Qianqing Xu Zijian Yuan Fang song State Key Laboratory of Metal Matrix Composites School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Structural reconstruction of electrocatalysts plays a pivotal role in catalytic performances for CO_(2)reduction reaction(CO_(2)RR),whereas the behavior is by far superficially ***,we report that CO_(2)accessibility results in a universal self-adaptive structural reconstruction from Cu_(2)O to Cu@CuxO composites,ending with feeding gas-dependent microstructures and catalytic *** CO_(2)-rich atmosphere favors reconstruction for CO_(2)RR,whereas the CO_(2)-deficient one prefers that for hydrogen evolution *** the assistance of spectroscopic analysis and theoretical calculations,we uncover a CO_(2)-induced passivation behavior by identifying a reductionresistant but catalytic active Cu(I)-rich amorphous layer stabilized by*CO ***,we find extra CO production is indispensable for the robust production of *** inverse correlation between durability and FECO/FEC2H4 is disclosed,suggesting that the selfstabilization process involving the absorption of*CO intermediates on Cu(I)sites is essential for durable *** by this insight,we design hollow Cu_(2)O nanospheres for durable and selective CO_(2)RR electrolysis in producing *** work recognizes the previously overlooked passivation reconstruction and self-stabilizing behavior and highlights the critical role of the local atmosphere in modulating reconstruction and catalytic processes.

关键词： CO_(2)reduction reaction Electrocatalysts Cu_(2)O Reconstruction Self-adaptive electrocatalysis

Primary cilia in corneal development and disease

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Zoological Research 2020年第5期41卷 495-502页

作者： ting song Jun Zhou Institute of Biomedical Sciences Shandong Provincial Key Laboratory of Animal Resistance BiologyCollaborative Innovation Center of Cell Biology in Universities of ShandongCollege of Life SciencesShandong Normal UniversityJinanShandong 250014China State Key Laboratory of Medicinal Chemical Biology College of Life SciencesNankai UniversityTianjin 300071China

As a transparent avascular tissue located at the front of the eyeball, the cornea is an important barrier to external damage. Both epithelial and endothelial cells of the cornea harbor primary cilia, which sense changes in the external environment and regulate intracellular signaling pathways. Accumulating evidence suggests that the primary cilium regulates corneal development in several ways, including participation in corneal epithelial stratification and maintenance of corneal endothelial cell *** addition, the primary cilium has been implicated in the pathogenesis of several corneal diseases. In this review, we discuss recent findings that demonstrate the critical role of the primary cilium in corneal development. We also discuss the link between ciliary dysfunction and corneal diseases, which suggests that the primary cilium could be targeted to treat these diseases.

关键词： Cornea Development Disease Cilium Epithelium Endothelium Treatment

Material Removal Model Considering Influence of Curvature Radius in Bonnet Polishing Convex Surface

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Chinese Journal of Mechanical Engineering 2015年第6期28卷 1109-1116页

作者： song Jianfeng yao Yingxue College of Mechanical Engineering Yanshan University Digital Manufacturing Laboratory of Mechatronicas Engineering College Harbin Institute Technology

The bonnet tool polishing is a novel, advanced and ultra-precise polishing process, by which the freeform surface can be polished. However, during the past few years, not only the key technology of calculating the dwell time and controlling the surface form in the bonnet polishing has been little reported so far, but also little attention has been paid to research the material removal function of the convex surface based on the geometry model considering the influence of the curvature radius. Firstly in this paper, for realizing the control of the freeform surface automatically by the bonnet polishing, on the basis of the simplified geometric model of convex surface, the calculation expression of the polishing contact spot on the convex surface considering the influence of the curvature radius is deduced, and the calculation model of the pressure distribution considering the influence of the curvature radius on the convex surface is derived by the coordinate transformation. Then the velocity distribution model is built in the bonnet polishing the convex surface. On the basis of the above research and the semi-experimental modified Preston equation obtained from the combination method of experimental and theoretical derivation, the material removal model of the convex surface considering the influence of the curvature radius in the bonnet polishing is established. Finally, the validity of the model through the simulation method has been validated. This research presents an effective prediction model and the calculation method of material removal for convex surface in bonnet polishing and prepares for the bonnet polishing the free surface numerically and automatically.

关键词： bonnet polishing convex surface material removal model curvature radius

Characteristics of dihydroflavonol 4-reductase gene promoters from different leaf colored Malus crabapple cultivars

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Horticulture Research 2017年第1期4卷 32-41页

作者： Ji Tian Meng-chen Chen Jie Zhang Ke-ting Li ting-ting song Xi Zhang Yun-cong yao Department of Plant Science and Technology Beijing University of AgricultureBeijing102206China Beijing Collaborative Innovation Center for Eco-Environmental Improvement with Forestry and Fruit Trees Beijing102206China

Anthocyanins are secondary metabolites in land plants that contribute to the colors of leaves and flowers,and are nutritionally valuable components of the human *** DFR gene plays an important role in the anthocyanin biosynthetic *** this study,we investigated the regulation of DFR expression and in different Malus crabapple cultivars that show distinct patterns of leaf coloration,and how it influences leaf anthocyanin accumulation and ***,we studied the ever-red leaved cultivar‘Royalty’,the ever-green leaved cultivar‘Flame’and the spring-red leaved cultivar‘Radiant’.RT-PCR analysis showed that the expression of McDFR1 correlated with the expression of a MYB transcription factor,McMYB10,and with anthocyanin *** isolated five McDFR1 promoter fragments from the three cultivars and identified four different fragments(F1–4)that were present either in several cultivars,or only in *** one-hybrid and electrophoretic mobility shift assay analyses showed that McMYB10 could bind to all the McDFR1 promoters,except *** F1,F2 and F3 fragments did not affect McMYB10 binding to the McDFR1 promoters;however,we found evidence that the F4 fragment suppressed binding,and that the MYBGAHV amino-acid sequence maybe an important cis-element for McMYB10 protein *** information has potential value for strategies to modify plant color through genetic transformation.

关键词： cultivar colored flowers

Multilevel analysis of the central-peripheral-target organ pathway:contributing to recovery after peripheral nerve injury

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Neural Regeneration Research 2025年第10期20卷 2807-2822页

作者： Xizi song Ruixin Li Xiaolei Chu Qi Li Ruihua Li Qingwen Li Kai-Yu Tong Xiaosong Gu Dong Ming Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Haihe Laboratory of Brain-Machine Interface and Human-Machine Fusion TianjinChina Department of Rehabilitation Tianjin University Tianjin HospitalTianjinChina Department of Hand Microsurgery Tianjin University Tianjin HospitalTianjinChina School of Exercise and Health Tianjin University of SportTianjinChina Department of Biomedical Engineering the Chinese University of Hong KongHong Kong Special Administrative RegionChina

Peripheral nerve injury is a common neurological condition that often leads to severe functional limitations and *** on the pathogenesis of peripheral nerve injury has focused on pathological changes at individual injury sites,neglecting multilevel pathological analysis of the overall nervous system and target *** has led to restrictions on current therapeutic *** this paper,we first summarize the potential mechanisms of peripheral nerve injury from a holistic perspective,covering the central nervous system,peripheral nervous system,and target *** peripheral nerve injury,the cortical plasticity of the brain is altered due to damage to and regeneration of peripheral nerves;changes such as neuronal apoptosis and axonal demyelination occur in the spinal *** nerve will undergo axonal regeneration,activation of Schwann cells,inflammatory response,and vascular system regeneration at the injury *** damage to target organs can occur,including skeletal muscle atrophy and sensory receptor *** then provide a brief review of the research advances in therapeutic approaches to peripheral nerve *** main current treatments are conducted passively and include physical factor rehabilitation,pharmacological treatments,cell-based therapies,and physical ***,most treatments only partially address the problem and cannot complete the systematic recovery of the entire central nervous system-peripheral nervous system-target organ ***,we should further explore multilevel treatment options that produce effective,long-lasting results,perhaps requiring a combination of passive(traditional)and active(novel)treatment methods to stimulate rehabilitation at the central-peripheral-target organ levels to achieve better functional recovery.

关键词： central nervous system central peripheral target organ multilevel pathological analysis nerve regeneration peripheral nerve injury peripheral nervous system target organs therapeutic approach

MoS_(2)Lubricate‑Toughened MXene/ANF Composites for Multifunctional Electromagnetic Interference Shielding

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Nano-Micro Letters 2025年第2期17卷 358-371页

作者： Jiaen Wang Wei Ming Longfu Chen Tianliang song Moxi Yele Hao Zhang Long Yang Gegen Sarula Benliang Liang Luting Yan Guangsheng Wang School of Physical Science and Engineering Beijing Jiaotong UniversityBeijing 100044People’s Republic of China Key Laboratory of Bio‑Inspired Smart Interfacial Science and Technology of Ministry of Education School of ChemistryBeihang UniversityBeijing 100191People’s Republic of China

The design and fabrication of high toughness electromagnetic interference(EMI)shielding composite films with diminished reflection are an imperative task to solve electromagnetic pollution *** MXene/ANF(aramid nanofibers)–MoS_(2)composite films with nacre-like layered structure here are fabricated after the introduction of MoS_(2)into binary MXene/ANF composite *** introduction of MoS_(2)fulfills an impressive“kill three birds with one stone”improvement effect:lubrication toughening mechanical performance,reduction in secondary reflection pollution of electromagnetic wave,and improvement in the performance of photothermal *** the introduction of MoS_(2)into binary MXene/ANF(mass ratio of 50:50),the strain to failure and tensile strength increase from 22.1±1.7%and 105.7±6.4 MPa and to 25.8±0.7%and 167.3±9.1 MPa,*** toughness elevates from 13.0±4.1 to 26.3±0.8 MJ m^(−3)(~102.3%)*** the reflection shielding effectiveness(SE_(R))of MXene/ANF(mass ratio of 50:50)decreases~10.8%.EMI shielding effectiveness(EMI SE)elevates to 41.0 dB(8.2–12.4 GHz);After the introduction of MoS_(2)into binary MXene/ANF(mass ratio of 60:40),the strain to failure increases from 18.3±1.9%to 28.1±0.7%(~53.5%),the SE_(R)decreases~22.2%,and the corresponding EMI SE is 43.9 *** MoS_(2)also leads to a more efficient photothermal conversion performance(~45 to~55℃).Additionally,MXene/ANF–MoS_(2)composite films exhibit excellent electric heating performance,quick temperature elevation(15 s),excellent cycle stability(2,2.5,and 3 V),and long-term stability(2520 s).Combining with excellent mechanical performance with high MXene content,electric heating performance,and photothermal conversion performance,EMI shielding ternary MXene/ANF–MoS_(2)composite films could be applied in many industrial *** work broadens how to achieve a balance between mechanical properties and versatility of composites in the case of high-function fillers.

关键词： MXene-MoS_(2) Lubrication toughening EMI shielding Photothermal conversion Electric heating performance

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饱和土不排水计算理论与方法探究

岩土工程学报 2025年第1期47卷 1-29页

作者：宋二祥清华大学土木水利学院北京100084

饱和土不排水强度及变形计算是岩土工程中颇具难度的复杂课题,至今业内对其多方面的问题仍存争议。结合笔者多年的相关学习研究,对此课题进行了较系统深入的探究。首先讨论了饱和土不排水计算的总应力法与有效应力法及各自的局限,并从... 详细信息

饱和土不排水强度及变形计算是岩土工程中颇具难度的复杂课题,至今业内对其多方面的问题仍存争议。结合笔者多年的相关学习研究,对此课题进行了较系统深入的探究。首先讨论了饱和土不排水计算的总应力法与有效应力法及各自的局限,并从有限元基本方程阐述了孔隙水压的处理,指出不管采用何种方法均应注意区分两类孔隙水压和两种总应力,即“土水分算”。随后,审视了Skempton-Henkel超静水压计算公式对不同应力路径的计算准确性,将它与MC强度准则相结合构建了饱和土不排水强度模型,对等向固结与不等向固结下饱和土不排水强度特性进行了分析,可为实际工程计算中强度参数选取提供参考。建议实际不排水计算采用广义Tresca强度准则,针对采用MC强度准则按有效应力法进行不排水计算会有较大误差的问题,除指出应直接输入不排水强度外,还给出一种采用等代强度参数的处理方法。在上述讨论基础上,剖析了固结不排水强度指标(CU指标)的缺陷,指出仅当土中总应力路径与测定CU指标的试验中相同时,用此指标直接计算才能给出准确的结果,特别是对地基承载力问题直接用此指标计算会给出严重偏危险的结果。还对基坑工程中主动、被动土水压力采用CU指标并土水合算的问题进行了分析,建议了合理计算方法及相应公式;对发生不排水极限土压时的滑移面倾角这一业内多人深感困惑的问题也进行了探讨。最后,针对饱和地基承载力及短期沉降计算,剖析了业内现行方法的问题,在深入解读有关因素影响机理的基础上给出新的计算方法。所给承载力计算公式,可较准确统一计算排水和不排水条件下的承载力,能更好保证设计的安全经济;所给沉降计算新方法能较准确计算饱和地基的短期沉降,对地基的排水沉降也可望取得较好结果,值得进一步发展完善。

关键词：饱和黏性土不排水强度超静水压固结不排水强度指标地基承载力地基沉降

Effects of Sea-Surface Waves and Ocean Spray on Air-Sea Momentum Fluxes

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Advances in Atmospheric Sciences 2018年第4期35卷 469-478页

作者： ting ZHANG Jinbao song Ocean College Zhejiang University State Key Laboratory of Satellite Ocean Environment Dynamics Second Institute of OceanographyState Oceanic Administration

The effects of sea-surface waves and ocean spray on the marine atmospheric boundary layer （MABL） at different wind speeds and wave ages were investigated. An MABL model was developed that introduces a wave-induced component and spray force to the total surface stress. The theoretical model solution was determined assuming the eddy viscosity coefficient varied linearly with height above the sea surface. The wave-induced component was evaluated using a directional wave spectrum and growth rate. Spray force was described using interactions between ocean-spray droplets and wind-velocity shear. Wind profiles and sea-surface drag coefficients were calculated for low to high wind speeds for wind-generated sea at different wave ages to examine surface-wave and ocean-spray effects on MABL momentum distribution. The theoretical solutions were compared with model solutions neglecting wave-induced stress and/or spray stress. Surface waves strongly affected near-surface wind profiles and sea-surface drag coefficients at low to moderate wind speeds. Drag coefficients and near-surface wind speeds were lower for young than for old waves. At high wind speeds, ocean-spray droplets produced by wind-tearing breaking-wave crests affected the MABL strongly in comparison with surface waves, implying that wave age affects the MABL only negligibly. Low drag coefficients at high wind caused by ocean-spray production increased turbulent stress in the sea-spray generation layer, accelerating near-sea-surface wind. Comparing the analytical drag coefficient values with laboratory measurements and field observations indicated that surface waves and ocean spray significantly affect the MABL at different wind speeds and wave ages.

关键词： drag coefficient marine atmospheric boundary layer ocean spray droplets surface waves

Hydrogen sulfide reduces oxidative stress in Huntington's disease via Nrf2

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Neural Regeneration Research 2025年第6期20卷 1776-1788页

作者： Zige Jiang Dexiang Liu tingting Li Chengcheng Gai Danqing Xin Yijing Zhao Yan song Yahong Cheng Tong Li Zhen Wang Department of Physiology School of Basic Medical SciencesCheeloo College of MedicineShandong UniversityJinanShandong ProvinceChina Department of Medical Psychology and Ethics School of Basic Medicine SciencesCheeloo College of MedicineShandong UniversityJinanShandong ProvinceChina Department of Neurosurgery Surgery Qingdao Municipal HospitalQingdaoShandong ProvinceChina

The pathophysiology of Huntington's disease involves high levels of the neurotoxin quinolinic acid. Quinolinic acid accumulation results in oxidative stress, which leads to neurotoxicity. However, the molecular and cellular mechanisms by which quinolinic acid contributes to Huntington's disease pathology remain unknown. In this study, we established in vitro and in vivo models of Huntington's disease by administering quinolinic acid to the PC12 neuronal cell line and the striatum of mice, respectively. We observed a decrease in the levels of hydrogen sulfide in both PC12 cells and mouse serum, which was accompanied by down-regulation of cystathionine β-synthase, an enzyme responsible for hydrogen sulfide production. However, treatment with NaHS(a hydrogen sulfide donor) increased hydrogen sulfide levels in the neurons and in mouse serum, as well as cystathionine β-synthase expression in the neurons and the mouse striatum, while also improving oxidative imbalance and mitochondrial dysfunction in PC12 cells and the mouse striatum. These beneficial effects correlated with upregulation of nuclear factor erythroid 2-related factor 2 expression. Finally, treatment with the nuclear factor erythroid 2-related factor 2inhibitor ML385 reversed the beneficial impact of exogenous hydrogen sulfide on quinolinic acid-induced oxidative stress. Taken together, our findings show that hydrogen sulfide reduces oxidative stress in Huntington's disease by activating nuclear factor erythroid 2-related factor 2,suggesting that hydrogen sulfide is a novel neuroprotective drug candidate for treating patients with Huntington's disease.

关键词： apoptosis cystathionine-β-synthase nuclear factor erythroid 2-related factor 2 Huntington's disease hydrogen sulfide mitochondrion neuroplasticity oxidative stress quinolinic acid reactive oxygen species

Low‑Temperature Fabrication of Stable Black‑Phase CsPbI_(3)Perovskite Flexible Photodetectors Toward Wearable Health Monitoring

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Nano-Micro Letters 2025年第3期17卷 232-245页

作者： Yingjie Zhao Yicheng Sun Chaoxin Pei Xing Yin Xinyi Li Yi Hao Mengru Zhang Meng Yuan Jinglin Zhou Yu Chen Yanlin song College of Chemistry and Pingyuan Laboratory Zhengzhou UniversityZhengzhou 450001People’s Republic of China Key Laboratory of Green Printing Institute of ChemistryChinese Academy of SciencesBeijing 100190People’s Republic of China Key Laboratory of Bio‑Inspired Materials and Interfacial Science Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190People’s Republic of China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049People’s Republic of China

Flexible wearable optoelectronic devices fabricated fromorganic–inorganic hybrid perovskites significantly accelerate the developmentof portable energy,biomedicine,and sensing fields,but their poor thermal stabilityhinders further ***,all-inorganic perovskites possessexcellent thermal stability,but black-phase all-inorganic perovskite filmusually requires high-temperature annealing steps,which increases energy consumptionand is not conducive to the fabrication of flexible wearable *** this work,an unprecedented low-temperature fabrication of stable blackphaseCsPbI3perovskite films is demonstrated by the in situ hydrolysis reactionof diphenylphosphinic chloride *** released diphenyl phosphateand chloride ions during the hydrolysis reaction significantly lower the phasetransition temperature and effectively passivate the defects in the perovskitefilms,yielding high-performance photodetectors with a responsivity of 42.1 AW−1 and a detectivity of 1.3×10^(14)***,high-fidelity imageand photoplethysmography sensors are demonstrated based on the fabricated flexible wearable *** work provides a newperspective for the low-temperature fabrication of large-area all-inorganic perovskite flexible optoelectronic devices.

关键词： In situ hydrolyzation Low-temperature processing All-inorganic perovskite Flexible photodetectors Health monitoring