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Characterization of edible bird’s nest by peptide fingerprinting with principal component analysis

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Food Quality and Safety 2017年第1期1卷 83-92页

作者： Chun-Fai Wong Gallant Kar-Lun Chan Ming-Lu Zhang Ping Yao Huang-Quan Lin Tina ting-xia Dong Geng Li xiao-Ping Lai Karl Wah-Keung Tsim Division of Life Science and Center for Chinese Medicine R&D The Hong Kong University of Science and TechnologyClear Water BayKowloon HKUST Shenzhen Research Institute Hi-Tech ParkNanshan School of Chinese Herbal Medicine Guangzhou University of Chinese Medicine Dongguan Mathematical Engineering Academy of Chinese Medicine Guangzhou University of Chinese MedicineChina

OBJECTIVES:Proteins are the major component and play a key role in nutritious and therapeutic functions of edible bird’s nest(EBN);however,limited studies have been conducted on the protein due to difficulties in extraction,isolation as well as *** study aimed to provide comprehensive information for the quality evaluation of EBN peptides,which would be a valuable reference for further study on EBN ***:Here,we developed a quality control method using high performance liquid chromatography(HPLC)peptide fingerprints deriving from EBN being digested with simulated gastric *** characteristic peptide peaks were collected and identified by LC-MS/***:The characteristic peptide peaks,corresponding to the protein fragments of acidic mammalian chitinase-like,lysyl oxidase,and Mucin-5AC-like,were identified and ***,the principal component analysis indicated that the fingerprints were able to discriminate colour of EBN(white/red)and production sites(cave/house)of White EBN on the same weight *** proposed by the model developed in this study,Muc-5AC-like and AMCaselike proteins were the markers with the highest discriminative ***:The overall findings suggest that HPLC peptide fingerprints were able to clearly demonstrate peptide profile differences between genuine and adulterated EBN samples;and classify EBN samples by its color and production *** addition,the protein identification results suggested that Muc-5AC-like protein was the major protein in EBN.

关键词： Edible bird’s nest Peptide fingerprint Mucin-5AC-like Acidic mammalian chitinase-like Principal component analysis

A CT-based radiomics nomogram for prediction of human epidermal growth factor receptor 2 status in patients with gastric cancer

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Chinese Journal of Cancer Research 2020年第1期32卷 62-71页

作者： Yexing Li Zixuan Cheng Olivier Gevaert Lan He Yanqi Huang Xin Chen xiaomei Huang xiaomei Wu Wen Zhang Mengyi Dong Jia Huang Yucun Huang ting xia Changhong Liang Zaiyi Liu Department of Radiology Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhou 510080China Graduate College Shantou University Medical CollegeShantou 515041China School of Medicine South China University of TechnologyGuangzhou 510006China Stanford Center for Biomedical Informatics Research Department of Medicineand Department of Biomedical Data ScienceStanford UniversityCalifornia 94305USA Graduate College Southern Medical UniversityGuangzhou 510515China Department of Radiology Guangzhou First People’s HospitalGuangzhou 510180China Department of Radiology Zhuhai Hospital of Traditional Chinese and Western MedicineZhuhai 519000China Department of Radiology The Fifth People’s Hospital of ZhuhaiZhuhai 519055China

Objective: To develop and validate a computed tomography(CT)-based radiomics nomogram for predicting human epidermal growth factor receptor 2(HER2) status in patients with gastric ***: This retrospective study included 134 patients with gastric cancer(HER2-negative: n=87;HER2-positive: n=47) from April 2013 to March 2018, who were then randomly divided into training(n=94) and validation(n=40) cohorts. Radiomics features were obtained from the CT images showing gastric cancer. Least absolute shrinkage and selection operator(LASSO) regression analysis was utilized for building the radiomics signature. A multivariable logistic regression method was applied to develop a prediction model incorporating the radiomics signature and independent clinicopathologic risk predictors, which were then visualized as a radiomics nomogram. The predictive performance of the nomogram was assessed in the training and validation ***: The radiomics signature was significantly associated with HER2 status in both training(P<0.001) and validation(P=0.023) cohorts. The prediction model that incorporated the radiomics signature and carcinoembryonic antigen(CEA) level demonstrated good discriminative performance for HER2 status prediction,with an area under the curve(AUC) of 0.799 [95% confidence interval(95% CI): 0.704-0.894] in the training cohort and 0.771(95% CI: 0.607-0.934) in the validation cohort. The calibration curve of the radiomics nomogram also showed good calibration. Decision curve analysis showed that the radiomics nomogram was ***: We built and validated a radiomics nomogram with good performance for HER2 status prediction in gastric cancer. This radiomics nomogram could serve as a non-invasive tool to predict HER2 status and guide clinical treatment.

关键词： Gastric cancer human epidermal growth factor receptor 2 radiomics X ray computed tomography

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碱土金属原子激光的共振辐射俘获效应

物理学报 2006年第4期55卷 1793-1797页

作者：毛邦宁潘佰良陈钢夏婷婷浙江大学物理系杭州310027

根据Holstein理论研究了碱土金属原子激光中的共振辐射俘获效应,分别计算了Ca,Sr和Ba蒸气激光在不同半径时产生共振辐射俘获效应的阈值温度、基态粒子数密度和共振能级的有效寿命.发现计算得到的阈值温度与实验报道的开始产生激光的工... 详细信息

根据Holstein理论研究了碱土金属原子激光中的共振辐射俘获效应,分别计算了Ca,Sr和Ba蒸气激光在不同半径时产生共振辐射俘获效应的阈值温度、基态粒子数密度和共振能级的有效寿命.发现计算得到的阈值温度与实验报道的开始产生激光的工作温度一致,表明共振辐射俘获效应是这类激光形成粒子数反转的一个重要机制.

关键词：共振辐射俘获碱土金属原子激光阈值温度 Holstein理论

3-7岁攻击性儿童的攻击性意图认知和行为预期研究

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华南师范大学学报（社会科学版） 2005年第1期 125-128页

作者：冯夏婷华南师范大学教育科学学院广东广州510631

本研究选择了 3 -7岁的攻击性儿童和非攻击性儿童各 3 3人 ,通过实验研究了攻击性儿童和非攻击性儿童的意图认知和行为预期方面的差异。研究结果表明 ,攻击性儿童容易把别人的行为判断为具有攻击性意图 ,攻击性儿童的行为预期能力不如... 详细信息

本研究选择了 3 -7岁的攻击性儿童和非攻击性儿童各 3 3人 ,通过实验研究了攻击性儿童和非攻击性儿童的意图认知和行为预期方面的差异。研究结果表明 ,攻击性儿童容易把别人的行为判断为具有攻击性意图 ,攻击性儿童的行为预期能力不如非攻击性儿童 ,他们容易作出攻击性的行为预期。

关键词： 3—7岁儿童攻击性儿童社会认知意图认知行为预期

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融合食用菌形象特征的食用菌品牌设计策略

中国食用菌 2020年第4期39卷 157-159页

作者：夏婷婷绍兴职业技术学院建筑与设计艺术学院浙江绍兴312000

对融合菌类形象特征的食用菌品牌的设计策略开展研究,讨论了菌类形象在食用菌品牌传播价值、经济价值和审美价值上采取的策略;探讨了食用菌品牌设计的费用问题。食用菌品牌设计为食用菌企业拓展国际市场空间、增强国际市场的影响力和竞... 详细信息

对融合菌类形象特征的食用菌品牌的设计策略开展研究,讨论了菌类形象在食用菌品牌传播价值、经济价值和审美价值上采取的策略;探讨了食用菌品牌设计的费用问题。食用菌品牌设计为食用菌企业拓展国际市场空间、增强国际市场的影响力和竞争力提供了有力的支撑。

关键词：食用菌品牌品牌设计价值策略

我国高等教育资源配置与培植——基于计划体制与市场体制的比较

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华东经济管理 2015年第12期29卷 180-184页

作者：夏婷婷彭勃合肥幼儿师范高等专科学校安徽合肥230011 淮北师范大学教育学院安徽淮北235000

计划经济体制和市场经济体制是两种不同的资源配置方式。在这两种资源配置方式条件下,高等教育资源在高等教育系统内部的配置和培植也各不相同,从而对高等教育发展产生不同的影响,出现不同的发展局面。比较计划经济体制和市场经济体制... 详细信息

计划经济体制和市场经济体制是两种不同的资源配置方式。在这两种资源配置方式条件下,高等教育资源在高等教育系统内部的配置和培植也各不相同,从而对高等教育发展产生不同的影响,出现不同的发展局面。比较计划经济体制和市场经济体制这两种不同的高等教育资源配置和培植方式,探寻它们与高等教育内在发展逻辑之间的互动关系,对深入理解我国高等教育发展道路和建设更高水平高等教育体系,具有重要意义。

关键词：计划经济体制市场经济体制高等教育资源配置与培植

锦屏二级水电站深埋引水隧洞群允许最小间距研究

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岩土力学 2008年第3期29卷 656-662页

作者：江权冯夏庭周辉中国科学院武汉岩土力学研究所岩土力学与工程国家重点实验室武汉430071

锦屏二级水电站引水隧洞群最大的特点是埋藏深、地应力高、外水压力大。这一极端复杂的赋存环境给4条引水隧洞的中心线间距确定带来了很大的挑战。为此,首先通过流-固耦合的数值计算方法,对洞间岩体塑性区贯通与否、隧洞壁面关键点位移... 详细信息

锦屏二级水电站引水隧洞群最大的特点是埋藏深、地应力高、外水压力大。这一极端复杂的赋存环境给4条引水隧洞的中心线间距确定带来了很大的挑战。为此,首先通过流-固耦合的数值计算方法,对洞间岩体塑性区贯通与否、隧洞壁面关键点位移曲线拐点、收敛位移是否超出相关规范共3种判别标准进行分析后,得到引水隧洞群最小理论间距值为50m。进而在类比与引水隧洞本身相邻的辅助洞和国内外几个典型深埋隧洞的洞径、埋深和间距的基础上,综合确定深埋引水隧洞群的最小允许中心线间距为52m,为当前设计采用60m洞间距提供了有力的理论支持。

关键词：锦屏级二水电站引水隧洞最小允许间距塑性区贯通位移拐点收敛位移

P型浮空发射区结构参数对IBC太阳电池电学性能的影响

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硅酸盐通报 2018年第10期37卷 3367-3371页

作者：林涛夏婷婷江苏联合职业技术学院南京工程分院南京211135

首先,利用TCAD半导体器件仿真软件对比分析了在无前表面结构、N型前表面场(Front Surface Field,FSF)及P型前表面浮空发射区(Front Floating Emitter,FFE)三种不同情况下N型插指背接触(Interdigitated Back Contact,IBC)太阳电池的输出... 详细信息

首先,利用TCAD半导体器件仿真软件对比分析了在无前表面结构、N型前表面场(Front Surface Field,FSF)及P型前表面浮空发射区(Front Floating Emitter,FFE)三种不同情况下N型插指背接触(Interdigitated Back Contact,IBC)太阳电池的输出特性。然后详细分析了FFE表面浓度和扩散深度对IBC太阳电池转换效率的影响,并在不同的前表面复合速率、背表面发射区覆盖比例及衬底电阻率情况下,针对FFE对IBC太阳电池电学性能的改善效果进行分析和评价,同时给出不同情况下最优的FFE结构参数。仿真结果表明:相比于FSF结构,FFE结构对IBC太阳电池电学性能的改善效果更显著。FFE表面浓度越高,峰值转换效率对应的扩散深度越小。在不同前表面复合速率、发射区覆盖比例及衬底电阻率情况下,FFE对IBC太阳电池转换效率的改善效果不同。在较高的前表面复合速率和较低的发射区覆盖比例情况下,FFE对电池转换效率的改善效果更加显著,对于较高的衬底电阻率情况,FFE对电池转换效率的改善效果与较低衬底电阻率的情况基本相同。

关键词：背接触太阳电池浮空发射区表面浓度扩散深度转换效率

A review of rockburst:Insights from engineering sites to theoretical investigations

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Journal of Central South University 2024年第8期31卷 2607-2643页

作者： HE Ben-guo WANG Biao FENG xia-ting ZHANG Heng-yuan JIN Zhao-tong Key Laboratory of Ministry of Education on Safe Mining of Deep Metal Mines Northeastern UniversityShenyang 110819China

Rockburst has perennially posed a formidable challenge to the stability of underground engineering works,particularly under conditions of deep-seated high *** paper provides a comprehensive review of recent advancements in on-site research related to rockburst occurrences,covering on-site case analyses,monitoring methodologies,early warning systems,and risk(proneness)***,the concepts and classifications of rockburst based on on-site understanding were *** influences of structural planes(in various spatial distribution combinations),in-situ stress(particularly magnitude and direction of the principal stress),dynamic disturbances,and excavation profiles on rockburst were thoroughly assessed and discussed through the analysis of published rockburst cases and on-site survey ***,a compendium of commonly employed on-site monitoring techniques was outlined,delineating their respective technical *** emphasis is accorded to the efficacy of microseismic monitoring technology and its prospective utility in facilitating dynamic rockburst early warning *** upon this foundation,the feasibility of assessing rockburst propensity while considering on-site variables is verified,encompassing the selection and quantitative evaluation of pertinent ***,a comprehensive synthesis of the paper is presented,alongside the articulation of prospective research goals for the future.

关键词： rockburst in-situ stress structural plane dynamic disturbance rockburst proneness evaluation