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Petroleum Science 2024年第4期21卷 2311-2328页

作者： Jian-Ping Huang wei-ting Peng Ji-Dong Yang Lu-Feng Lou School of Geosciences China University of Petroleum (East China) Pilot National Laboratory for Marine Science and Technology (Qingdao)

Finite-difference(FD) method is the most extensively employed numerical modeling technique. Nevertheless, when using the FD method to simulate the seismic wave propagation, the large spatial or temporal sampling interval can lead to dispersion errors and numerical instability. In the FD scheme, the key factor in determining both dispersion errors and stability is the selection of the FD weights. Thus,How to obtain appropriate FD weights to guarantee a stable numerical modeling process with minimum dispersion error is critical. The FD weights computation strategies can be classified into three types based on different computational ideologies, window function strategy, optimization strategy, and Taylor expansion strategy. In this paper, we provide a comprehensive overview of these three strategies by presenting their fundamental theories. We conduct a set of comparative analyses of their strengths and weaknesses through various analysis tests and numerical modelings. According to these comparisons, we provide two potential research directions of this field: Firstly, the development of a computational strategy for FD weights that enhances stability; Secondly, obtaining FD weights that exhibit a wide bandwidth while minimizing dispersion errors.

关键词： Finite-difference scheme FD coefficients Dispersion error Forward modeling Numerical simulation

Plasma Metabonomics of Human Adenovirus-infected Patients with Pneumonia and Upper Respiratory Tract Infection

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Current Medical Science 2024年第1期44卷 121-133页

作者： ting-ting wei Wen XU Bo TU Wan-xue ZHANG Xin-xin YANG Yiguo ZHOU Shan-shan ZHANG Jun-lian YANG Ming-zhu XIE Juan DU wei-wei CHEN Qing-bin LU Department of Epidemiology and Biostatistics School of Public HealthPeking UniversityBeijing 100191China Department of Infectious Disease The Fifth Medical Center of Chinese PLA General HospitalNational Clinical Research Center for Infectious DiseasesBeijing 100039China Department of Laboratorial Science and Technology&Vaccine Research Center School of Public HealthPeking UniversityBeijing 100191China Department of Health Policy and Management School of Public HealthPeking UniversityBeijing 100191China Global Center for Infectious Disease and Policy Research&Global Health and Infectious Diseases Group Peking UniversityBeijing 100191China Key Laboratory of Epidemiology of Major Diseases(Peking University) Ministry of EducationBeijing 100191China

Objective Human adenovirus(HAdV)infection is common and can develop to serious conditions with high mortality,yet the mechanism of HAdV infection remains *** the present study,the serum metabolite profiles of HAdV-7-infected patients with pneumonia or upper respiratory tract infection(URTI)were *** In total,35 patients were enrolled in the study following an outbreak of HAdV-7 in the army,of whom 14 had pneumonia and 21 had *** samples were collected at the acute stage and at the recovery stage and were analyzed by untargeted *** Over 90% of the differential metabolites identified between the pneumonia patients and URTI patients were lipids and lipid-like molecules,including glycerophospholipids,fatty acyls,and *** metabolic pathways that were significantly enriched were primarily the lipid metabolism pathways,including sphingolipid metabolism,glycerophospholipid metabolism,and linoleic acid *** sphingolipid metabolism was identified as a significantly differential pathway between the pneumonia patients and URTI patients and between the acute and recovery stages for the pneumonia patients,but not between the acute and recovery stages for the URTI *** and lactosylceramide,involved in sphingolipid metabolism,were significantly higher in the pneumonia patients than in the URTI patients with good discrimination abilities[area under curve(AUC)0.742 and 0.716,respectively;combination AUC 0.801].Conclusion Our results suggested that HAdV modulated lipid metabolism for both the patients with URTI and pneumonia,especially the sphingolipid metabolism involving ceramide and lactosylceramide,which might thus be a potential intervention target in the treatment of HAdV infection.

关键词： human adenovirus metabonomic lipids pneumonia upper respiratory tract infection

Hepatocellular Carcinoma with Gastric Metastasis Mimicking a 4 cm Gastrointestinal Stromal Tumor After a 3-year Disease-free Interval

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Journal of Clinical and Translational Hepatology 2024年第2期12卷 218-221页

作者： wei-ting Chen Shiu-Feng Kathy Huang Ming-Ling Chang Yun-Fan Liaw Division of Hepatology Department of Gastroenterology and HepatologyChang Gung Memorial HospitalTaoyuan Department of Medicine College of MedicineChang Gung UniversityTaoyuan Division of Molecular and Genomic Medicine National Health Research InstitutesMiaoli

Hepatocellular carcinoma(HCC)is an aggressive tumor that usually occurs in patients with chronic liver disease and *** resection is an optimal treatment for HCC,but the 5-year recurrence rates are significantly *** majority of recurrent HCCs occur through intrahepatic metastasis with local tumor progression,and less than 20%of recurrences are extrahepatic *** with gastric metastasis is extremely rare,and it is easily misdiagnosed as primary gastric cancer with liver *** 80-yearold male chronic hepatitis B virus carrier had received lamivudine and entecavir for years and was regularly followed up in the *** had a 3.5 cm solitary HCC with microvascular invasion and received curative surgical resection in *** 2013,he developed a 1.3 cm solitary HCC again and was treated with combination therapy with radiofrequency ablation and pure ethanol ***,he was followed every 3–6 months and was *** years later,in 2016,endoscopy for intermittent epigastralgia showed a solitary 4 cm intraluminal gastric subepithelial tumor without mucosal ulcers or erosions over the gastric *** imaging studies,including computed tomography,favored the diagnosis of gastrointestinal stromal tumor(GIST),but the pathology of the tumor proved to be *** patient did not receive any systemic anticancer therapy but only wedge resection of the stomach and remained tumor-and HCC-free until his latest clinic visit in *** current case is unique and indicates the possibility of HCC with late solitary gastric metastasis mimicking *** gastric tumor resection ensured an extremely good outcome for the patient,which is different from the devastating prognosis of most cases of HCC with gastric metastasis.

关键词： Hepatocellular carcinoma Hepatitis B virus Gastric Gastrointestinal stromal tumor

Application of artifcial intelligence in cataract management:current and future directions

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Eye and Vision 2024年第1期10卷 21-30页

作者： Laura Gutierrez Jane Sujuan Lim Li Lian Foo wei Yan Ng Michelle Yip Gilbert Yong San Lim Melissa Hsing Yi Wong Allan Fong Mohamad Rosman Jodhbir Singth Mehta Haotian Lin Darren Shu Jeng ting Daniel Shu wei ting Singapore Eye Research Institute SingaporeSingapore Singapore National Eye Center 11 Third Hospital AvenueSingapore 168751Singapore Academic Ophthalmology School of MedicineUniversity of NottinghamNottinghamUK Zhongshan Ophthalmic Center Sun Yet Sen UniversityGuangzhouChina

The rise of artifcial intelligence(AI)has brought breakthroughs in many areas of *** ophthalmology,AI has delivered robust results in the screening and detection of diabetic retinopathy,age-related macular degeneration,glaucoma,and retinopathy of *** management is another feld that can beneft from greater AI *** is the leading cause of reversible visual impairment with a rising global clinical *** diagnosis,monitoring,and surgical management are necessary to address this *** addition,patients in large developing countries often sufer from limited access to tertiary care,a problem further exacerbated by the ongoing COVID-19 *** on the other hand,can help transform cataract management by improving automation,efcacy and overcoming geographical ***,AI can be applied as a telediagnostic platform to screen and diagnose patients with cataract using slit-lamp and fundus *** utilizes a deep-learning,convolutional neural network(CNN)to detect and classify referable cataracts ***,some of the latest intraocular lens formulas have used AI to enhance prediction accuracy,achieving superior postoperative refractive results compared to traditional ***,AI can be used to augment cataract surgical skill training by identifying diferent phases of cataract surgery on video and to optimize operating theater workfows by accurately predicting the duration of surgical ***,some AI CNN models are able to efectively predict the progression of posterior capsule opacifcation and eventual need for YAG laser *** advances in AI could transform cataract management and enable delivery of efcient ophthalmic *** key challenges include ethical management of data,ensuring data security and privacy,demonstrating clinically acceptable performance,improving the generalizability of AI models across heterogeneous populations,and improving the trust of e

关键词： Artifcial intelligence Telemedicine Cataract Cataract screening Cataract surgery IOL calculations Biometry Machine learning

Can soil organic carbon sequestration and the carbon management index be improved by changing the film mulching methods in the semiarid region?

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Journal of Integrative Agriculture 2024年第5期23卷 1541-1556页

作者： Jialin Yang Liangqi Ren Nanhai Zhang Enke Liu Shikun Sun Xiaolong Ren Zhikuan Jia ting wei Peng Zhang College of Agronomy Northwest A&F UniversityYangling 712100China Key Laboratory of Crop Physi-Ecology and Tillage Science in Northwestern Loess Plateau Ministry of Agriculture and Rural AfairsNorthwest A&FUniversityYangling 712100China Institute of Environment and Sustainable Development in Agriculture Chinese Academy of Agricultural SciencesBeijing 100081China College of Water Resources and Architectural Engineering Northwest A&F UniversityYangling 712100China

Plastic film mulching has been widely used to increase maize yield in the semiarid area of ***, whether long-term plastic film mulching is conducive to agricultural sustainability in this region remains controversial.A field experiment was initiated in 2013 with five different film mulching methods:(i) control method, flat planting without mulching (CK),(ii) flat planting with half film mulching (P),(iii) film mulching on ridges and planting in narrow furrows(S),(iv) full film mulching on double ridges (D), and (v) film mulching on ridges and planting in wide furrows (R).The effects on soil organic carbon (SOC) content, storage, and fractions, and on the carbon management index (CMI)were evaluated after nine consecutive years of plastic film *** results showed that long-term plastic film mulching generally maintained the initial SOC *** with no mulching, plastic film mulching increased the average crop yield, biomass yield, and root biomass by 48.38, 35.06, and 37.32%, respectively, which led to the improvement of SOC ***, plastic film mulching significantly improved CMI, and increased the SOC content by 13.59%, SOC storage by 7.47%and easily oxidizable organic carbon (EOC) by 13.78%on average,but it reduced the other labile *** sequestration and CMI were improved by refining the plastic film mulching *** S treatment had the best effect among the four mulching methods, so it can be used as a reasonable film mulching method for sustainable agricultural development in the semiarid area.

关键词： plastic film mulching soil organic carbon labile organic carbon fractions semiarid area

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Cross section determination of^(27)Al(n,2n)^(26)Al reaction induced by 14-MeV neutrons uniting with D-T neutron activation and AMS techniques

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Nuclear Science and Techniques 2024年第6期35卷 78-89页

作者： Xian-Lin Yang Chang-Lin Lan Yu-ting wei Yi Zhang Gong Jiang Bo Xie Yu Liu Hong-Tao Shen Xiao-Jun Sun School of Nuclear Science and Technology Lanzhou UniversityLanzhou 730000China MOE Frontiers Science Center for Rare Isotopes Lanzhou UniversityLanzhou 730000China State Key Laboratory of Environmental Geochemistry Institute of GeochemistryChinese Academy of SciencesGuiyang 550081China Guangxi Key Laboratory of Nuclear Physics and Nuclear Technology Guangxi Normal UniversityGuilin 541004China

Aluminum is the primary structural material in nuclear engineering,and its cross section induced by 14-MeV neutrons is of great *** address the issue of insufficient accuracy for the^(27)Al(n,2n)^(26)Al reaction cross section,the activation method and accelerator mass spectrometry(AMS)technique were used to determine the^(27)Al(n,2n)^(26)Al cross section,which could be used as a D-T plasma ion temperature monitor in fusion *** the China Academy of Engineering Physics,neutron activation was performed using a K-400 neutron generator produced by the T(d,n)4He ***^(26)Al∕^(27)Al isotope ratios were measured using the newly installed GYIG 1 MV AMS at the Institute of Geochemistry,Chinese Academy of *** neutron flux was monitored by measuring the activity of 92mNb produced by the 93Nb(n,2n)92mNb *** measured results were compared with available data in the experimental nuclear reaction database,and the measured values showed a reasonable degree of consistency with partially available literature *** newly acquired cross-sectional data at 12 neutron energy points through systematic measurements clarified the divergence,which has two different growth trends from the existing experimental *** obtained results are also compared with the corresponding evaluated database,and the newly calculated excitation functions with TALYS−1.95 and EMPIRE−3.2 codes,the agreement with CENDL−3.2,TENDL-2021 and EMPIRE−3.2 results are generally acceptable.A substantial improvement in the knowledge of the^(27)Al(n,2n)^(26)Al reaction excitation function was obtained in the present work,which will lay the foundation for the diagnosis of the fusion ion temperature,testing of the nuclear physics model,evaluation of nuclear data,etc.

关键词： 14-MeV neutron ^(27)Al(n,2n)^(26)Al Cross section AMS

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Klebsiella pneumoniae infections after liver transplantation:Drug resistance and distribution of pathogens,risk factors,and influence on outcomes

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World Journal of Hepatology 2024年第4期16卷 612-624页

作者： Long Guo Peng Peng wei-ting Peng Jie Zhao Qi-Quan Wan Department of Respiratory and Critical Care Medicine The Third Xiangya Hospital of Central South UniversityChangsha 410013Hunan ProvinceChina Clinical Laboratory Medicine Center Zhuzhou Hospital Affiliated to Xiangya School of MedicineCentral South UniversityZhuzhou 421007Hunan ProvinceChina The Second Affiliated Hospital Class Xiangya School of MedicineCentral South UniversityChangsha 410013Hunan ProvinceChina Department of Liver Surgery Renji HospitalShanghai Jiaotong University School of MedicineShanghai 200127China Department of Transplant Surgery The Third Xiangya Hospital of Central South UniversityChangsha 410013Hunan ProvinceChina Engineering and Technology Research Center for Transplantation Medicine of National Health Commission The Third Xiangya Hospital of Central South UniversityChangsha 410013Hunan ProvinceChina

BACKGROUND Liver transplantation(LT)is the only curative treatment for end-stage liver ***,LT recipients are susceptible to infection,which is the leading cause of early mortality after *** pneumoniae infections(KPIs)in the bloodstream are common in LT *** hypothesized that KPIs and carbapenemresistant Klebsiella pneumoniae(CRKP)infections may affect the outcomes of LT *** To assess KPI incidence,timing,distribution,drug resistance,and risk factors following LT and its association with *** This retrospective study included 406 patients undergoing LT at The Third Xiangya Hospital of Central South University,a tertiary hospital,from January 2015 to January *** investigated the risk factors for KPIs and assessed the impact of KPIs and CRKP infections on the prognosis of LT recipients using logistic regression *** KPI incidence was 7.9%(n=32),with lung/thoracic cavity the most frequent site of infection;the median time from LT to KPI onset was 7.5 *** 44 Klebsiella pneumoniae isolates,43(97.7%)and 34(77.3%)were susceptible to polymyxin B or ceftazidime/avibactam and tigecycline,respectively;>70%were resistant to piperacillin/tazobactam,ceftazidime,cefepime,aztreonam,meropenem,and *** sex[odds ratio(OR)=2.827,95%confidence interval(CI):1.256-6.364;P=0.012],pre-LT diabetes(OR=2.794,95%CI:1.070-7.294;P=0.036),day 1 post-LT alanine aminotransferase(ALT)levels≥1500 U/L(OR=3.645,95%CI:1.671-7.950;P=0.001),and post-LT urethral catheter duration over 4 d(OR=2.266,95%CI:1.016-5.054;P=0.046)were risk factors for *** infections,but not KPIs,were risk factors for 6-month all-cause mortality *** KPIs occur frequently and rapidly after *** factors include female sex,pre-LT diabetes,increased post-LT ALT levels,and urethral catheter *** infections,and not KPIs,affect mortality.

关键词： Liver transplantation Klebsiella pneumoniae infections Carbapenem-resistant Klebsiella pneumoniae Risk factors Outcomes

Influencer Identification of Threshold Models in Hypergraphs

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Journal of Mathematical Research with Applications 2024年第5期 569-582页

作者： Xiaojuan SONG Xilong QU ting wei Jilei TAI Renquan ZHANG School of Mathematical Sciences Dalian University of Technology

This paper mainly studies the influence maximization problem of threshold models in hypergraphs, which aims to identify the most influential nodes in hypergraphs. Firstly, we introduce a novel information diffusion rule in hypergraphs based on Threshold Models and conduct the stability analysis. Then we extend the CI-TM algorithm, originally designed for complex networks, to hypergraphs, denoted as the H-CI-TM algorithm. Secondly, we use an iterative approach to get the globally optimal solutions. The analysis reveals that our algorithm ultimately identifies the most influential set of nodes. Based on the numerical simulations, HCI-TM algorithm outperforms several competing algorithms in both synthetic and real-world hypergraphs. Essentially, when provided with the same number of initial seeds, our algorithm can achieve a larger activation size. Our method not only accurately assesses the influence of individual nodes but also identifies a set of nodes with greater impact. Furthermore, our results demonstrate good scalability when handling intricate relationships and large-scale *** outcomes of our research provide substantial support for the applications of the threshold models across diverse fields, including social network analysis and marketing strategies.

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Dinitrophenyl-oxadiazole compounds:Design strategy,synthesis,and properties of a series of new melt-cast explosives

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Defence Technology（防务技术） 2024年第5期35卷 100-107页

作者： Bao-long Kuang ting-wei Wang Cong Li Mou Sun Qamar-un-Nisa Tariq Chao Zhang Zhi-ming Xie Zu-jia Lu Jian-guo Zhang State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing100081China China Wuzhou Engineering Group CO. LTD.Beijing 100053China

Melt-cast explosives are the most widely used energetic materials in military composite explosives,researchers have been unremittingly exploring high-energy and insensitive melt-cast *** this work,a series of dinitrophenyl-oxadiazole compounds were designed and *** compounds have an ideal low melting point(80-97℃),good detonation performance(detonation velocity D=6455-6971 m/s,detonation pressure P=18-19 GPa)and extreme insensitive nature(impact sensitivity≥60 J,friction sensitivity>360 N).All these compounds were well characterized by nuclear magnetic resonance,fourier transform infrared spectroscopy,elemental *** 2,3 were unambiguously confirmed by X-ray single crystal diffraction *** a result,their overall properties are superior to traditional melt-cast explosives trinitrotoluene(TNT)and dinitroanisole(DNAN)which may have excellent potential applications in insensitive melt-cast explosives.

关键词： Dinitrophenyl-oxadiazole Melt-cast explosive Low sensitivity

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Composition， Distribution and Constraint Factors of Fe Isotope(δFe) in the Surface Soils of the Tibetan Plateau

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Journal of Earth Science 2024年

作者： ting wei Zhiwen Dong Eric Parteli Xiaoli Liu Shichang Kang Yaping Shao State Key Laboratory of Cryosphere Sciences， Northwest Institute of Eco-Environment and Resources， Chinese Academy of Sciences Hubei Key Laboratory of Regional Ecology and Environmental Change， School of Geography and Information Engineering， China University of Geosciences Faculty of Physics， University of Duisburg-Essen Institute for Geophysics and Meteorology， University of Cologne

Iron isotopes， represented by δ56Fe， serve as valuable tools for constraining the surface iron processes and as potent tracers for studying the biogeochemical cycle of iron. Nevertheless， our comprehension of iron isotopes in the land surface processes of the Tibetan Plateau （TP） remains limited. In this study， we present the results of iron isotopic composition (δ56Fe) in the surface soils of the TP， encompassing both glacial and non-glacial regions characterized by rugged and flat topographies. Our findings reveal that soil δ56Fe values ranged from -0.01±0.05‰ to 0.14±0.01‰， with the highest values observed in eastern locations （0.14‰） and the lowest appeared in the northeast （-0.1‰）. On a global scale， the δ56Fe values observed in Tibetan soils exhibited relatively small variability compared to reservoirs marked by significant iron isotope fractionation. By contrast， the range of TP soils measured here was slightly larger than that of the Chinese Loess. Furthermore， we discerned noticeable spatial variations in δ56Fe across the large-scale region of TP， indicating a gradual increase trend from the northeast to the south and from the west to the east. These regional disparities in δ56Fe likely arise from a combination of constraining factors， including differences in mineralogy， lithological variations， organic matter content， and variations in chemical weathering intensity. This study is pivotal in advancing our understanding of land surface iron isotope δ56Fe dynamics and its role in the biogeochemical cycle within the TP region.

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