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Predictability of the upper ocean heat content in a Community Earth System Model ensemble prediction system

Acta Oceanologica Sinica 2024年第1期43卷 1-10页

作者： ting liu Wenxiu Zhong State Key Laboratory of Satellite Ocean Environment Dynamics Second Institute of OceanographyMinistry of Natural ResourcesHangzhou 310012China Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai 519082China School of Atmospheric Sciences Sun Yat-Sen UniversityZhuhai 519082China

Upper ocean heat content(OHC)has been widely recognized as a crucial precursor to high-impact climate variability,especially for that being indispensable to the long-term memory of the *** the predictability of OHC using state-of-the-art climate models is invaluable for improving and advancing climate *** developed retrospective forecast experiments,based on a Community Earth System Model ensemble prediction system,offer a great opportunity to comprehensively explore OHC *** results indicate that the skill of actual OHC predictions varies across different oceans and diminishes as the lead time of prediction *** spatial distribution of the actual prediction skill closely resembles the corresponding persistence skill,indicating that the persistence of OHC serves as the primary predictive signal for its *** decline in actual prediction skill is more pronounced in the Indian and Atlantic oceans than in the Pacific Ocean,particularly within tropical ***,notable seasonal variations in the actual prediction skills across different oceans align well with the phase-locking features of OHC *** potential predictability of OHC generally surpasses the actual prediction skill at all lead times,highlighting significant room for improvement in current OHC predictions,especially for the North Indian Ocean and the Atlantic *** such improvements necessitates a collaborative effort to enhance the quality of ocean observations,develop effective data assimilation methods,and reduce model bias.

关键词： ocean heat content prediction skill retrospective forecast experiment

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Novel Sum-of-Sinusoids Simulation Channel Modeling for 6G Multiple-Input Multiple-Output Vehicle-to-Everything Communications

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China Communications 2024年第1期21卷 242-259页

作者： Hao Jiang Hongming Zhang ting liu College of Artificial Intelligence Nanjing University of Information Science and Technology210044China National Mobile Communications Research Laboratory Southeast UniversityNanjing 210096China School of Information and Communication Engineering Beijing University of Posts and TelecommunicationsChina

In this paper,a statistical cluster-based simulation channel model with a finite number of sinusoids is proposed for depicting the multiple-input multiple-output(MIMO)communications in vehicleto-everything(V2X)*** the proposed sum-of-sinusoids(SoS)channel model,the waves that emerge from the transmitter undergo line-of-sight(LoS)and non-line-of-sight(NLoS)propagation to the receiver,which makes the model suitable for describing numerous V2X wireless communication scenarios for sixth-generation(6G).We derive expressions for the real and imaginary parts of the complex channel impulse response(CIR),which characterize the physical propagation characteristics of V2X wireless *** statistical properties of the real and imaginary parts of the complex CIRs,i.e.,autocorrelation functions(ACFs),Doppler power spectral densities(PSDs),cross-correlation functions(CCFs),and variances of ACFs and CCFs,are derived and *** results are generated and match those predicted by the underlying theory,demonstrating the accuracy of our derivation and *** proposed framework and underlying theory arise as an efficient tool to investigate the statistical properties of 6G MIMO V2X communication systems.

关键词： complex CIRs LoS and NLoS propagation components MIMO V2X communication environments SoS simulation channel model statistical properties

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Asymmetric Partial Hydrosilylation of 2,2-Difluoro-1,3-diketones with Chiral Frustrated Lewis Pairs

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Chinese Journal of Chemistry 2024年第8期42卷 853-857页

作者： ting liu Xiangqing Feng Haifeng Du Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Molecular Recognition and FunctionInstitute of ChemistryChinese Academy of SciencesBeijing100190 China University of Chinese Academy of Sciences Beijing100049 China

Comprehensive Summary,The asymmetric partial reduction of 1,3-diketones stands as a straightforward pathway to access optically active β-hydroxyketones. In this paper, an asymmetric Piers-type hydrosilylation of 2,2-difluoro-1,3-diketones was successfully realized by using a frustrated Lewis pair of chiral borane and tricyclohexylphosphine as a catalyst, delivering a variety of α,α-difluoro-β-hydroxyketones in high yields with up to 99% ee. Significantly, no over-reduced diol products were observed even with an excess amount of silanes. The product can be conveniently converted to α,α-difluoro-β-hydroxyester or 1,3-anti-diol via an oxidation with m-CPBA or a reduction with DIBAL-H without obvious loss of ee.

关键词： Asymmetric catalysis Hydrosilylation Ketones Frustrated Lewis pairs Chiral boranes

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Non-contact and full-field online monitoring of curing temperature during the in-situ heating process based on deep learning

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Advances in Manufacturing 2024年第1期12卷 167-176页

作者： Qiang-Qiang liu Shu-ting liu Ying-Guang Li Xu liu Xiao-Zhong Hao College of Mechanical and Electrical Engineering Nanjing University of Aeronautics and AstronauticsNanjing210016People’s Republic of China School of Mechanical and Power Engineering Nanjing Tech UniversityNanjing211816People’s Republic of China

Online monitoring of the curing temperature field is essential to improving the quality and efficiency of the manufacturing process of composite *** embedded sensor-based technologies have difficulty monitoring the full temperature field or have to introduce heterogeneous items that could have an undesired impact on the *** this paper,a non-contact,full-field monitoring method based on deep learning that predicts the internal temperature field of composite parts in real time using surface temperature measurements of auxiliary materials is *** the proposed method,an average temperature monitoring accuracy of 97%is achieved in various heating *** addition,this method also demonstrates satisfying feasibility when a stronger thermal barrier covers the *** method was experimentally validated during the self-resistance electric heating process,in which the monitoring accuracy reached 93.1%.This method can potentially be applied to automated manufacturing and process control in the composites industry.

关键词： Online monitoring Curing temperature field Deep learning(DL) In-situ heating

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Tuning the selectivity of CO_(2)conversion to CO on partially reduced Cu_(2)O/ZnO heterogeneous interface

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Interdisciplinary Materials 2024年第3期3卷 380-388页

作者： Tianci Xiang ting liu ting Ouyang Shenlong Zhao Zhao-Qing liu School of Chemistry and Chemical Engineering/Institute of Clean Energy and Materials/Guangzhou Key Laboratory for Clean Energy and Materials/Huangpu Hydrogen Innovation Center Guangzhou Higher Education Mega CenterGuangzhou UniversityGuangzhouGuangdongPeople's Republic of China School of Chemical and Biomolecular Engineering The University of SydneySydneyNew South WalesAustralia

The development of stable and efficient low-cost electrocatalysts is conducive to the industrialization of CO_(2).The synergy effect between the heterogeneous interface of metal/oxide can promote the conversion of CO_(2).In this work,Cu_(2)O/ZnO heterostructures with partially reduced metal/oxide heterointerfaces in Zn plates(CZZ)have been synthesized for CO_(2)electroreduction in different cationic solutions(K^(+)and Cs^(+)).Physical characterizations were used to demonstrate the heterojunction of Cu_(2)O/ZnO and the heterointerfaces of metal/oxide,electrochemical tests were used to illustrate the enhancement of the selectivity of CO_(2)to CO in different cationic *** efficiency for CO with CZZ as catalyst reaches 70.9%in K+solution(current density for CO−3.77 mA cm^(−2)and stability 24 h),and the Faraday efficiency for CO is 55.2%in Cs^(+)solution(−2.47 mA cm^(−2)and 21 h).In addition,in situ techniques are used to elucidate possible reaction mechanisms for the conversion of CO_(2)to CO in K^(+)and Cs^(+)solutions.

关键词： CO CO_(2)reduction electrochemical catalysis heterogeneous interface

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In Situ Atomic Reconstruction Engineering Modulating Graphene-Like MXene-Based Multifunctional Electromagnetic Devices Covering Multi-Spectrum

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Nano-Micro Letters 2024年第9期16卷 247-261页

作者： ting‑ting liu Qi Zheng Wen‑Qiang Cao Yu‑Ze Wang Min Zhang Quan‑Liang Zhao Mao‑Sheng Cao School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081People’s Republic of China Department of Physics Beijing Technology and Business UniversityBeijing 100048People’s Republic of China School of Mechanical and Materials Engineering North China University of TechnologyBeijing 100144People’s Republic of China

With the diversified development of big data,detection and precision guidance technologies,electromagnetic(EM)functional materials and devices serving multiple spectrums have become a hot *** the multispectral response of materials is a challenging and meaningful scientific *** this study,MXene/TiO_(2)hybrids with tunable conduction loss and polarization relaxation are fabricated by in situ atomic reconstruction *** importantly,MXene/TiO_(2)hybrids exhibit adjustable spectral responses in the GHz,infrared and visible spectrums,and several EM devices are constructed based on *** antenna array provides excellent EM energy harvesting in multiple microwave bands,with|S11|up to−63.2 dB,and can be tuned by the degree of *** ultra-wideband bandpass filter realizes a passband of about 5.4 GHz and effectively suppresses the transmission of EM signals in the *** infrared stealth device has an emissivity of less than 0.2 in the infrared spectrum at wavelengths of 6-14μ*** work can provide new inspiration for the design and development of multifunctional,multi-spectrum EM devices.

关键词： Graphene-like MXene hybrids Multi-spectral response Multi-function antenna Ultra-wideband bandpass filter Electromagnetic device

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Combined proteomic and metabolomic studies on the liver of Amur sturgeon Acipenser schrenckii under titanium dioxide nanoparticle exposure

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Journal of Oceanology and Limnology 2024年第3期42卷 1001-1015页

作者： Zhou ZHOU ting liu Jie KONG Zhenxing ZHAO Junquan ZHU Key Laboratory of Aquacultural Biotechnology Ministry of Educationand Key Laboratory of Marine Biotechnology of Zhejiang ProvinceCollege of Marine SciencesNingbo UniversityNingbo 315000China Guizhou Fisheries Research Institute Guizhou Academy of Agriculture SciencesGuiyang 550000China

Nanomaterials,particularly titanium dioxide nanoparticles(TiO_(2)-NPs),are extensively utilized across various ***,their environmental release has raised concerns regarding their potential ecological and environmental *** reproductive toxicity of TiO_(2)-NPs in fish species has attracted considerable attention,yet conflicting research outcomes have been *** investigated the effects of TiO_(2)-NPs exposure on the liver of juvenile Amur sturgeon Acipenser schrenckii using label-free proteomic and untargeted metabolomic *** experiment included a control group and three groups exposed to different concentrations of TiO_(2)-NPs(low,TL;medium,TM;high,TH).Compared to the control group,9,19,and 25 proteins and 35,73,and 158 metabolites were differentially expressed in the TH,TM,and TL TiO_(2)-NP-exposed groups,*** differentially expressed genes(DEGs)were enriched in the Kyoto Encyclopedia for Genes and Genomes(KEGG)pathways related to glycolysis and ***,among the 126 correlated proteins,the most enriched pathways were associated with endocytosis and protein processing in the endoplasmic ***,syringic acid was significantly downregulated across all three TiO_(2)-NP-exposed *** obtain a comprehensive overview of the TiO_(2)-NP-induced expression changes,a co-regulated network of proteins and metabolites associated with TiO_(2)-NPs exposure was *** to TiO_(2)-NPs led to enrichment and alteration of pathways related to immune responses,including endocytosis,protein processing in the endoplasmic reticulum,and peroxisome proliferator-activated receptor(PPAR)*** conclusion,our findings indicate that exposure to TiO_(2)-NPs might disrupt glucose metabolism and induce immune responses,thus contributing to our understanding of the environmental impacts of nanomaterials and highlighting the need for further research and development of potential mitigation strategies.

关键词： TiO_(2)-nanoparticle exposure proteomics metabolomics glucose metabolism immune response

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Effect of Ti Particles on the Microstructure and Mechanical Properties of AZ91 Magnesium Matrix Composites

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Acta Metallurgica Sinica(English Letters) 2024年第3期37卷 513-524页

作者： Lu Xiao ting-ting liu Yue Chu Bo Song Jie Zhao Xian-Hua Chen Kai-Hong Zheng Fu-Sheng Pan College of Materials Science and Engineering Chongqing UniversityChongqing 400044China lntelligent Manufacturing and Automobile School Chongqing College of Electronic EngineeringChongqing 401331China School of Materials and Energy Southwest UniversityChongqing 400715China Science and Technology Research Institute of CNNC 404 Co.LTD Gansu 735100China Institute of New Materials Guangdong Academy of SciencesGuangzhou 510650China

Spherical micro-Ti particle(TiP)-reinforced AZ91 magnesium alloy composites were fabricated by semi-solid stirring assisted ultrasonic vibration,which were then subjected to hot *** microstructure results showed that the addition of Ti particles refined the grain size and decreased the texture intensity of the as-extruded AZ91 *** Al3Ti phase with a thickness of 100 nm formed at the Ti/Mg interface,which had a non-coherent relationship with the magnesium *** as-extruded 1 vol.%TiP/AZ91 composite exhibited the best comprehensive mechanical properties,with yield strength,ultimate tensile strength,and elongation at break of 366 MPa,456 MPa,and 14.6%,respectively,which were significantly higher than those of the AZ91 ***,the addition of Ti particles can improve the strength and ductility of the AZ91 alloy,demonstrating the value of magnesium matrix composites for commercial applications.

关键词： Magnesium matrix composites Ti particles Interface Mechanical properties

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Moderate expression of CD39 in GPC3-CAR-T cells shows high efficacy against hepatocellular carcinoma

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Frontiers of Medicine 2024年第4期18卷 708-720页

作者： Fan Zou Jialiang Wei Jialang Zhuang Yafang liu Jizhou Tan Xianzhang Huang ting liu Guangdong Cardiovsacular Institute Guangdong Provincial People’s HospitalGuangdong Academy of Medical ScienceGuangzhou510080China The Second Clinical Medical College Guangzhou University of Chinese MedicineDepartment of Laboratory Medicine/State Key Laboratory of Traditional Chinese Medicine SyndromeGuangdong Provincial Hospital of Chinese MedicineGuangzhou510120China Department of Medical Oncology The First Affiliated Hospital of Guangxi Medical UniversityNanning530021China Department of Stomatology the First Affiliated HospitalSun Yat-sen UniversityGuangzhou510080China Medical Research Institute Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Science)Southern Medical UniversityGuangzhou510080China School of Food and Drug Shenzhen Polytechnic UniversityShenzhen518055China Shenzhen Second People’s Hospital First Affiliated Hospital of Shenzhen UniversityShenzhen518055China

CD39 serves as a crucial biomarker for neoantigen-specific CD8^(+)T cells and is associated with antitumor activity and ***,the relationship between CD39 expression levels and the function of chimeric antigen receptor T(CAR-T)cells remains *** study aimed to investigate the role of CD39 in the functional performance of CAR-T cells against hepatocellular carcinoma(HCC)and explore the therapeutic potential of CD39 modulators,such as mitochondrial division inhibitor-1(mdivi-1),or knockdown CD39 through short hairpin *** findings demonstrated that glypican-3-CAR-T cells with moderate CD39 expression exhibited a strong antitumor activity,while high and low levels of CD39 led to an impaired cellular *** modulating the proportion of CD39 intermediate(CD39^(int))-phenotype CAR-T cells such as mdivi-1 and CD39 knockdown enhanced and impaired T cell function,*** combination of mdivi-1 and CD39 knockdown in CAR-T cells yielded the highest proportion of infiltrated CD39^(int)CAR-T cells and demonstrated a robust antitumor activity in *** conclusion,this study revealed the crucial role of CD39 in CAR-T cell function,demonstrated the potential therapeutic efficacy of combining mdivi-1 with CD39 knockdown in HCC,and provided a novel treatment strategy for HCC patients in the field of cellular immunotherapy.

关键词： CD39 CAR-T cells mdivi-1 hepatocellular carcinoma antitumor activity

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Personalized and continuous care intervention affects rehabilitation,living quality,and negative emotions of patients with breast cancer

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World Journal of Psychiatry 2024年第6期14卷 876-883页

作者： Ling-Xia Kong Yan-Hong Zhao Zhi-Lin Feng ting-ting liu Department of Breast Surgery The First Affiliated Hospital of Hebei North UniversityZhangjiakou 075000Hebei ProvinceChina Operating Room The First Affiliated Hospital of Hebei North UniversityZhangjiakou 075000Hebei ProvinceChina

BACKGROUND Breast cancer is among the most common malignancies *** progress in treatment methods and levels,the overall survival period has been prolonged,and the demand for quality care has *** To investigate the effect of individualized and continuous care intervention in patients with breast *** Two hundred patients with breast cancer who received systemic therapy at The First Affiliated Hospital of Hebei North University(January 2021 to July 2023)were retrospectively selected as research *** them,134 received routine care intervention(routing group)and 66 received personalized and continuous care(intervention group).Self-rating anxiety scale(SAS),self-rating depression scale(SDS),and Functional Assessment of Cancer Therapy-Breast(FACT-B)scores,including limb shoulder joint activity,complication rate,and care satisfaction,were compared between both groups after *** SAS and SDS scores were lower in the intervention group than in the routing group at one and three months after *** total FACT-B scores and five dimensions in the intervention group were higher than those in the routing group at three months of *** range of motion of shoulder anteflexion,posterior extension,abduction,internal rotation,and external rotation in the intervention group was higher than that in the routing group one month after *** incidence of postoperative complications was 18.18%lower in the intervention group than in the routing group(34.33%;Pting group(78.36%;P<0.05).CONCLUSION Personalized and continuous care can alleviate negative emotions in patients with breast cancer,quicken rehabilitation of limb function,decrease the incidence of complications,and improve living quality and care satisfaction.

关键词： Breast cancer Personalized care Continuous care Negative emotions Living quality Rehabilitation effect

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