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High performance hydroxyapatite ceramics and a triply periodic minimum surface structure fabricated by digital light processing 3D printing

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Journal of Advanced Ceramics 2021年第1期10卷 39-48页

作者： Yongxia YAO Wei QIN Bohang XING Na SHA ting jiao Zhe ZHAO School of Material Science and Engineering Shanghai Institute of TechnologyShanghai 201418China Department of Prosthodontics Shanghai Ninth People’s HospitalCollege of StomatologySchool of MedicineShanghai Jiao Tong UniversityShanghai 200011China Shanghai Key Laboratory of Stomatology&Shanghai Research Institute of Stomatology National Clinical Research Center for Oral DiseasesShanghai 200011China School of Chemical and Environment Engineering Shanghai Institute of TechnologyShanghai 201418China

High performance hydroxyapatite(HA)ceramics with excellent densification and mechanical properties were successfully fabricated by digital light processing(DLP)three-dimensional(3D)printing *** was found that the sintering atmosphere of wet C02 can dramatically improve the densification process and thus lead to better mechanical *** ceramics with a relative density of 97.12%and a three-point bending strength of 92.4 MPa can be achieved at a sintering temperature of 1300℃,which makes a solid foundation for application in bone ***,a relatively high compressive strength of 4.09 MPa can be also achieved for a DLP-printed p-cell triply periodic minimum surface(TPMS)structure with a porosity of 74%,which meets the requirement of cancellous bone substitutes.A further cell proliferation test demonstrated that the sintering atmosphere of wet CO2 led to improve cell vitality after 7 days of cell culture Moreover,with the possible benefit from the bio-inspired structure,the 3D-printed TPMS structure significantly improved the cell vitality,which is crucial for early osteogenesis and osteointegration.

关键词： hydroxyapatite(HA) 3D printing sintering atmosphere mechanical property bioactivity digital light processing(DLP)

Chidamide based combination regimen for treatment of monomorphic epitheliotropic intestinal T cell lymphoma following radical operation:Two case reports

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World Journal of Clinical Cases 2020年第7期8卷 1278-1286页

作者： ting-Zhi Liu Yi-Jia Zheng Zhan-Wen Zhang Shan-Shan Li jiao-ting Chen Ai-Hua Peng Ren-Wei Huang Department of Hematology The Sixth Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510655Guangdong ProvinceChina Department of Nuclear Medicine The Sixth Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510655Guangdong ProvinceChina Department of Oncology The Sixth Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510655Guangdong ProvinceChina

BACKGROUND Monomorphic epitheliotropic intestinal T cell lymphoma(MEITL)is a rare extranodal T-cell lymphoma that has uniformly aggressive features with a poor *** standardized treatment protocols have been *** experience has demonstrated favorable outcomes with combination chemotherapy followed by autologous hematopoietic stem cell ***,many patients are unable to tolerate the *** is a new histone deacetylase inhibitor that has shown preferential efficacy in mature T-cell *** SUMMARY We herein present two cases of MEITL who were both intermediate risk according to enteropathy-associated T cell lymphoma prognostic *** one was a 61-year-old *** complained of upper abdominal pain and intermittent black stool for 2 *** examination revealed that the intestinal wall was *** received a partial excision of the small intestine.A chidamidebased combination regimen was given *** months later,he presented with recurrence in the bilateral *** passed away 15 mo after his *** two was a 35-year-old woman who complained of abdominal distention for 1 *** emission tomography/computed tomography demonstrated wall thickening of the small intestine and upper sigmoid *** perforation and septic shock occurred on the fourth day of her *** was treated by sigmoid ***-based combination therapy was then *** was recurrence-free for 6 mo until lesions were found in the bilateral brain and lived for 17 mo since her *** to historical data,chidamide seems to improve the prognosis of MEITL *** MEITL is a type of aggressive *** is a new promising approach for the treatment of MEITL.

关键词： Monomorphic epitheliotropic intestinal T cell lymphoma Histone deacetylase inhibitor Chidamide Intensive chemotherapy Stem cell transplantation Case report

Maternal and neonatal blood vitamin D status and neurodevelopment at 24 months of age:a prospective birth cohort study

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World Journal of Pediatrics 2023年第9期19卷 883-893页

作者： Yue Zhang Chun-Yan Zhou Xi-Rui Wang Xian-ting jiao Jun Zhang Ying Tian Luan-Luan Li Chen Chen Xiao-Dan Yu Department of Developmental and Behavioral Pediatrics Shanghai Children’s Medical CenterSchool of MedicineShanghai Jiao Tong UniversityShanghai 200127China Translational Medicine Institute Shanghai Children’s Medical CenterSchool of MedicineShanghai Jiao Tong UniversityShanghai 200127China MOE-Shanghai Key Lab of Children’s Environmental Health Xinhua HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200092China

Background This study aimed to explore the relationship of 25-hydroxyvitamin D[25(OH)D]in three trimesters and at birth with neurodevelopment at 24 months of *** From 2013 to 2016,pregnant women from the Shanghai Birth Cohort in China were recruited for the ***,649 mother-infant pairs were *** 25(OH)D was measured with mass spectrometry in three trimesters,and cord blood was divided into deficiency(ting for confounding factors,cord blood 25(OH)D in the sufficient group was positively correlated with cognitive[β=11.43,95%confidence interval(CI)=5.65–17.22],language(β=6.01,95%CI=1.67–10.3),and motor scores(β=6.43,95%CI=1.73–11.1);cord blood 25(OH)D in the insufficient group was also positively correlated with cognitive scores(β=9.42,95%CI=3.74–15.11).Additionally,sufficient vitamin D status in the four periods and persistent 25(OH)D≥30 ng/mL throughout pregnancy were associated with a lower risk of suboptimal cognitive development in adjusted models,although the effects were attenuated after applying the false discovery rate *** Cord blood 25(OH)D≥12 ng/mL has a significant positive association with cognitive,language,and motor development at 24 months of *** vitamin D status in pregnancy might be a protective factor for suboptimal neurocognition development at 24 months of age.

关键词： 25-hydroxyvitamin D Children’s neurodevelopment Cord blood Maternal vitamin D status

Refractive outcomes after vitrectomy combined with phacoemulsification of idiopathic macular holes

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International Journal of Ophthalmology(English edition) 2021年第2期14卷 250-254页

作者： Bo-Shi Liu Wei-Na Cui Rui Niu Qiong Chen Ze-Tong Nie jiao-ting Wei Bo-Jie Hu Tianjin Key Laboratory of Retinal Functions and Diseases Tianjin International Joint Research and Development Centre of Ophthalmology and Vision ScienceEye Institute and School of OptometryTianjin Medical University Eye HospitalTianjin 300384China

AIM:To report the refractive outcomes after vitrectomy combined with phacoemulsification and intraocular lens(IOL)implantation(phaco-vitrectomy)in idiopathic macular holes(IMH).METHODS:A total of 56 eyes with IMH(IMH group)that underwent phaco-vitrectomy and 44 eyes with age-related cataract(ARC group)that underwent cataract surgery were retrospectively *** best corrective visual acuity(BCVA),predicted refractive error(PRE),actual refractive error(ARE),axial length(AL),were measured in both groups before and 6 mo after *** power calculation of IOL and the predicted refractive error(PRE)were calculated according to the SRK/T *** difference of PRE and ARE between the two groups were compared and ***:In the IMH group,the diameters of macular holes were 271.73±75.85μm,the closure rate was 100%.The pre-and post-operative BCVA were 0.80±0.35 and 0.40±0.35 log *** PRE of A-ultrasound and IOL Master in the IMH group was-0.27±0.25 and 0.10±0.66 *** postoperative mean absolute prediction error(MAE)was observed to be 0.58±0.65 and 0.53±0.37 D in the IOL Master and A-ultrasound(P=0.758).The PRE and ARE of the IMH group were 0.10±0.66 D and-0.19±0.64 D(P=0.102).The PRE and ARE of the ARC group was-0.43±0.95 and-0.31±0.93 D(P=0.383).The difference between PRE and ARE was-0.33±0.81 and 0.09±0.64 D in the IMH and ARC groups(P=0.021).The proportion of myopic shift was 67.9%in the IMH group and 27.3%in the ARC group(P=0.004).CONCLUSION:The myopic shift can be observed in patients with IMH after phaco-vitrectomy.

关键词： idiopathic macular hole vitrectomy phacoemulsification intraocular lens implantation refractive error myopic shift

Compressive resistances and failure modes of abutments with different transgingival heights and types on internal conical connected implants

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Compressive resistances and failure modes of abutments with ...

Analysis of postoperative ocular surface changes and intervention effect after pars plana vitrectomy in meibomian gland dysfunction dry eye patients

第十一次全国口腔修复学学术会议

作者： Chenyuan Zhu Fuqiang Zhang ting jiao Department of Prosthodontics Shanghai 9th People’s HospitalShanghai JiaoTong University

Purpose:This study aimed to research the effect of different transgingival heights(TH)and types of abutments on performances including the compressive resistances and fracture modes of abutments on internal conical connected *** and Methods:Three groups were established:a one-piece zirconia abutment group(group A),a twopiece zirconia abutment group(group B),and a one-piece titanium abutment group(group C).Three TH(2 mm,

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International Journal of Ophthalmology(English edition) 2023年第5期16卷 721-729页

作者： Bo-Shi Liu jiao-ting Wei Ze-Tong Nie Meng Yang Shao-Fang Pang Wen-Bo Li Xiao-Rong Li Bo-Jie Hu Tianjin Key Laboratory of Retinal Functions and Diseases Tianjin International Joint Research and Development Centre of Ophthalmology and Vision ScienceEye Institute and School of OptometryTianjin Medical University Eye HospitalTianjin 300384China

AIM:To observe ocular surface changes after phacovitrectomy in patients with mild to moderate meibomian gland dysfunction(MGD)-type dry eye and track clinical treatment response using a Keratograph 5M and a Lipi View ***:Forty cases were randomized into control group A and treatment group B;the latter received meibomian gland treatment 3d before phacovitrectomy and sodium hyaluronate before and after *** average non-invasive tear film break-up time(NITBUTav),first noninvasive tear film break-up time(NITBUTf),non-invasive measured tear meniscus height(NTMH),meibomian gland loss(MGL),lipid layer thickness(LLT)and partial blink rate(PBR)were measured preoperatively and 1wk,1 and 3mo ***:The NITBUTav values of group A at 1wk(4.38±0.47),1mo(6.76±0.70),and 3mo(7.25±0.68)were significantly lower than those of group B(7.45±0.78,10.46±0.97,and 11.31±0.89;P=0.002,0.004,and 0.001,respectively).The NTMH values of group B at 1wk(0.20±0.01)and 1mo(0.22±0.01)were markedly higher than those of group A(0.15±0.01 and 0.15±0.01;P=0.008 and P0.05).CONCLUSION:Mild to moderate MGD dry eye worsens in the short term after *** cleaning,hot compresses,and meibomian gland massage as well as preoperative and postoperative sodium hyaluronate promote the rapid recovery of tear film stability.

关键词： meibomian gland dysfunction dry eye non-invasive ocular surface analyser pars plana vitrectomy meibomian gland massage

Negative effects of enlarging internal limiting membrane peeling for idiopathic macular hole surgery

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International Journal of Ophthalmology(English edition) 2022年第11期15卷 1806-1813页

作者： Ze-Tong Nie Bo-Shi Liu Yong Wang Qiong Chen jiao-ting Wei Meng Yang Shao-Fang Pang Xiao-Rong Li Bo-Jie Hu Tianjin Key Laboratory of Retinal Functions and Diseases Tianjin Branch of National Clinical Research Center for Ocular DiseaseEye Institute and School of OptometryTianjin Medical University EyeHospitalTianjin 300384China

AIM: To observe the effects of the different extents of internal limiting membrane(ILM) peeling on the surgical success and anatomical and functional outcomes of idiopathic macular hole(IMH).METHODS: In this retrospective cohort study, 36 patients were reviewed and divided into two groups according to the extent of ILM peeling: group A(18 patients), with the peeling area within one-half of the optic disc macular distance as the radius;group B(18 patients), with the peeling area larger than that of group A but did not exceed the optic disc macular distance as the radius. The main outcomes included the best corrected visual acuity(BCVA), light-adaptive electroretinography, macular hole(MH) closure rate, central macular thickness(CMT), retinal nerve fiber layer(RNFL) and ganglion cell complex(GCC) thickness [nine regions based on the Early Treatment of Diabetic Retinopathy Study(ETDRS) ring] before and 1, 3, and 6mo after ***: The closure rate was 94.4%(17/18) both in groups A and B. The BCVA in both groups improved significantly compared with the preoperative values, but there was no difference between the two groups. The b-wave amplitude of the electroretinogram analysis was significantly improved in both groups compared to that of the preoperative period, with a greater increase in group A than in group B at 6mo(P=0.017). The CMT in both groups gradually decreased after surgery, and there was no difference between the two groups. The RNFL thickness of the temporal outer ring region in group B was significantly lower than that in group A at 3 and 6mo after surgery(P=0.010, 0.032). The GCC thickness of the temporal outer ring region in group B was significantly lower than that in group A at 6mo after surgery(P=0.038).CONCLUSION: Enlarging the extent of ILM peeling doesn’t affect the IMH closure rate and visual acuity recovery, but the greater the extent of peeling, the greater the damage to the inner retinal structures.

关键词： idiopathic macular hole internal limiting membrane light-adapted electroretinography retinal nerve fiber layer ganglion cell complex

组件多工作模式下的离散事件系统监督控制方法研究

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控制理论与应用 2020年第3期37卷 534-539页

作者：焦亭刘振国山西大学自动化系山西太原030006

针对组件多工作模式下的离散事件系统,提出一种监督控制方法.利用Ramadge-Wonham监督控制架构,计算出组件各工作模式下对应的监督控制器.然后,利用所提的merge算法将组件各工作模式下对应的监督控制器合并,以生成融合监督控制器.再利用... 详细信息

针对组件多工作模式下的离散事件系统,提出一种监督控制方法.利用Ramadge-Wonham监督控制架构,计算出组件各工作模式下对应的监督控制器.然后,利用所提的merge算法将组件各工作模式下对应的监督控制器合并,以生成融合监督控制器.再利用所提的事件选择函数得到在融合监督控制器各状态允许发生的事件,从而保证系统在融合监督控制器作用下的可控且非阻塞运行.最后,通过一个带反馈功能的制造系统演示本文所提方法的有效性,该系统中的检测单元将根据工件未通过检测的次数选择工作模式.相比于运用扩展有限状态机进行变量抽象的方法,本文所提方法更加直观简便,并能适应多个工件同时处于系统中时的情形.

关键词：离散事件系统监督控制理论多工作模式组件融合监督控制器

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含电转热氢装置的综合能源系统经济运行

电测与仪表 2022年第9期59卷 1-7页

作者：焦亭白宇山西大学自动化与软件学院太原030006

为解决富余电力对电网的冲击问题,需要为分布式电源配置储能装置,以提高综合能源系统运行经济性。将富余电力转化为氢气已经被证明是有效的处理方法,然而传统的电氢转换效率通常低于70%,且忽略了转换过程中的热损失问题。基于此,文中介... 详细信息

为解决富余电力对电网的冲击问题,需要为分布式电源配置储能装置,以提高综合能源系统运行经济性。将富余电力转化为氢气已经被证明是有效的处理方法,然而传统的电氢转换效率通常低于70%,且忽略了转换过程中的热损失问题。基于此,文中介绍了一种考虑热回收的电转氢技术,即电转热氢技术,将电转热氢技术应用于电解槽中,提出了一种含电转热氢装置的综合能源系统模型。同时,以购电成本、购气成本以及富余电力惩罚成本最小为目标,协同考虑电转热氢装置的温度特性,设计了三种不同的工作场景,使用改进粒子群优化算法求解可知,引入电转热氢装置后,系统交易成本降低了1.48万元。算例结果表明,电转热氢装置的加入能够有效提高综合能源系统的经济性,验证了所提模型的有效性。

关键词：综合能源系统电转热氢装置热损失温度特性改进粒子群优化算法