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Maluta's Coefficient of Musielak-Orlicz Sequence Spaces

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Acta Mathematica Sinica,English Series 2005年第4期21卷 699-704页

作者： Hui Li YAO ting fu WANG Department of Mathematics Harbin University of Science and Technology Harbin 150080. P. R. China

In this paper, we give the formula of Maluta＇s coefficient for calculation, and don＇t add any conditions to the generating function Ф.

关键词： Maluta's coefficient Musielak-Orlicz sequence spaces

FXR suppresses colorectal cancer by inhibiting the Wnt/β-catenin pathway via activation of TLE3

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Genes & Diseases 2023年第3期10卷 719-722页

作者： Xingchen Dong Chunmiao Cai ting fu Pharmaceutical Sciences Division School of PharmacyUniversity of Wisconsin Carbone Cancer Center(UWCCC)University of Wisconsin–MadisonMadisonWI 53705USA

Colorectal cancer(CRC)is the third most common and lethal cancer worldwide.1 Farnesoid X receptor(FXR)is a regulator of bile acid(BA)homeostasis and its expression is inversely correlated with the incidence of CRC.2,3 Moreover,our recent study discovered that dietary factors and dysregulated Wnt signaling independently alter BA profiles,some of which antagonize intestinal FXR,such as Tauro-β-muricholic acid(T-βMCA)and deoxycholic acid(DCA).

关键词： cancer inhibiting homeostasis

Preparation of porous structures on copper microchannel surfaces by laser writing

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Science China(Technological Sciences) 2019年第12期62卷 2261-2270页

作者： DENG DaXiang CHEN XiaoLong CHEN Liang LIAN YunSong fu ting School of Mechanical Engineering and Automation Harbin Institute of Technology(Shenzhen)Shenzhen 518055China Department of Mechanical&Electrical Engineering Xiamen UniversityXiamen 361005China Hubei Key Laboratory of Mechanical Transmission and Manufacturing Engineering Wuhan University of Science and TechnologyWuhan 430081China

A laser writing method is developed to fabricate porous structures on copper microchannel wall surfaces for enhanced microchannel heat sinks(MHSs). The formation feasibility together with its mechanism of such porous structures is explored by the comparison of dry and wet laser writing process, i.e., in both air atmosphere and under de-ionized water. Rectangular microchannels with ripples-like porous structures on the wall surfaces, which consisted of numerous micro-holes and micro-cavities,have been successfully formed in the dry laser writing process. Nevertheless, the microchannel wall surfaces were hardly altered in wet conditions. Besides, the effect of laser fluence on the formation of porous structures on the microchannels was also assessed in both dry and wet conditions. In dry laser writing process, the microchannel depth and surface roughness of wall surface increased monotonically, whereas the microchannel bottom width decreased continuously with increasing the laser fluence. On the other hand, the microchannel wall kept almost unchanged with smooth surfaces with increasing laser fluence in wet conditions.

关键词： laser writing porous surface microchannel heat sinks surface morphology

Progression of myopia among undergraduate students in central China

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International Journal of Ophthalmology(English edition) 2023年第2期16卷 274-279页

作者： ting fu Yan Xiang Jun-Ming Wang Department of Ophthalmology Tongji Hospital of Tongji Medical College of Huazhong University of Science and TechnologyWuhan 430030Hubei ProvinceChina

AIM:To investigate the progression of myopia and risk factors among university students in central ***:A total of 7359 first-year undergraduate students at Huazhong University of Science and Technology in central China were recruited to the study and invited to a centralized clinic for medical examination,including optometry,and re-examined after one *** analyses were performed to assess the associations between one-year myopia progression and various ***:The spherical equivalent refraction for the overall population was-3.14±2.28 D at *** rate of myopia progression over 0.50 D after one year was 41.9%,and the 1-year progression of myopia was-0.47±0.58 *** was no difference of mean 1-year myopia progression between male and female or difference among age *** myopia progression of original myopia was severer than progression of new-onset *** was also difference of mean myopia progression among different degrees of myopia at *** under corrected eyes had a higher percentage of myopia progression than well corrected eyes(χ^(2)=7.90,P0.05).CONCLUSION:Myopes still progress in undergraduate students,especially in high myopes.

关键词： myopia progression high myopia prevalence undergraduate students

Cell-SELEX-based aptamer-conjugated nanomaterials for cancer diagnosis and therapy

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National Science Review 2015年第1期2卷 71-84页

作者： Hong-Min Meng ting fu Xiao-Bing Zhang Weihong Tan Molecular Science and Biomedicine Laboratory State Key Laboratory of Chemo/Biosensing and ChemometricsCollege of Chemistry and Chemical EngineeringCollege of BiologyCollaborative Innovation Center for Molecular Engineering for TheranosticsHunan University

Nucleic acid aptamers, which are generated by a novel technique called SELEX(systematic evolution of ligands by exponential enrichment), have recently atracted signiicant atention in the ield of early detection and treatment of cancer based on their numerous merits, such as high ainity, high speciicity,small size, litle immunogenicity, stable structures, and ease of chemical modiication. furthermore,aptamers can gain more lexibility as cancer cell targeting tools when conjugated to nanomaterials,including metallic nanoparticles, carbon nanomaterials, DNA nanodevices, and polymeric *** discuss the progress achieved in cancer diagnosis and therapy through the conjugation of cell-SELEX-based aptamers with diferent nanomaterials.

关键词： aptamer cell-SELEX nanomaterial cancer cells cancer diagnosis and therapy

HEF-19-induced relaxation of colonic smooth muscles and the underlying mechanisms

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World Journal of Gastroenterology 2013年第32期19卷 5314-5319页

作者： Yuan-Yuan Wei Lu-Lu Sun Shou-ting fu Department of Pharmacy Beijing Shijitan HospitalCapital Medical University School of Life Science and Biopharmaceutics Shenyang Pharmaceutical University

AIM:To investigate the relaxant effect of chromane HEF-19 on colonic smooth muscles isolated from rabbits,and the underlying ***:The relaxant effect and action mechanisms of HEF-19 were investigated using descending colon smooth muscle of the *** 1 cm long were mounted in 15-mL tissue baths containing Tyrode’s solution,maintained at 37±0.5℃and aerated with a mixture of 5%CO2in oxygen(Carbogen).The tension and amplitude of the smooth muscle strips were recorded after adding HEF-19(10-6,10-5and 10-4mol/L).After cumulative administration of four antispasmodic agents,including acetylcholine chloride(Ach)(10-4mol/L),histamine(10-4mol/L),high-K+(60 mmol/L)and BaCl2(8.2 mmol/L),HEF-19(3×10-7-3×10-4mol/L)was added to investigate the relaxant effect of ***2(10-4-2.5×10-3mol/L)was added cumulatively to the smooth muscle preparations pretreated with and without HEF-19(1×10-6or 3×10-6mol/L)and verapamil(1×10-7mol/L)to study the mechanisms ***,phasic contraction was induced with ACh(15×10-6mol/L),and CaCl2(4×10-3mol/L)was added to the smooth muscle preparations pretreated with and without HEF-19(3×10-6mol/L or 1×10-5mol/L)and verapamil(1×10-7mol/L)in calcium-free medium to further study the underlying ***:HEF-19(1×10-6,1×10-5and 1×10-4mol/L)suppressed spontaneous contraction of rabbit colonic smooth ***-19(3×10-7-3×10-4mol/L)relaxed in a concentration-dependent manner colonic smooth muscle preparations pre-contracted with BaCl2,high-K+solution,Ach or histamine with respective EC50values of 5.15±0.05,5.12±0.08,5.58±0.16and 5.25±0.24,thus showing a spasmolytic ***-19(1×10-6mol/L and 3×10-6mol/L)shifted the concentration-response curves of CaCl2to the right and depressed the maximum response to *** two components contracted by Ach were attenuated with HEF-19(3×10-6mol/L or 10-5mol/L)in calcium-free ***:HEF-19 inhibited rabbit colonic smooth muscle contraction,probably through in

关键词： Colonic smooth muscle Smooth muscle relaxation Ca2+channels

Prediction of Rolling Load in Hot Strip Mill byInnovations Feedback Neural Networks

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Journal of Iron and Steel Research International 2007年第2期14卷 42-45,51页

作者： ZHANG Li ZHANG Li-yong WANG Jun MA fu-ting School of Electronic and Information Engineering Dalian University of Technology Dalian 116023 Liaoning China State Key Laboratory of Rolling an.d Automation Northeastern University Shenyang 110006 Liaoning China

Because the structure of the classical mathematical model of rolling load is simple, even with the self-adapting technology, it is difficult to accommodate the increasing dimensional accuracy. Motivated by this fact, an Innovations Feedback Neural Networks （IFNN） was presented based on the idea of Kalman prediction. The neural networks used the Back Propagation （BP） algorithm and applied it to the prediction of rolling load in hot strip mill. The theoretical results and the off-line simulation show that the prediction capability of IFNN is better than that of normal BP networks, namely, for the prediction of the rolling load in hot strip mill, the prediction precision of IFNN is higher than that of normal BP networks. Finally, a relative complete rolling load prediction system was developed on Windows 2003/XP platform using the OOP programming method and the SQL server2000 database. With this sys- tem, the rolling load of a 1700 strip mill was calculated, and the prediction results obtained correspond well with the field data. It shows that IFNN is valid for rolling load prediction.

关键词： rolling load prediction innovation neural network hot strip mill

Effect of stagger angle on capillary performance of microgroove structures with reentrant cavities

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Science China(Technological Sciences) 2021年第7期64卷 1436-1446页

作者： SUN YaLong LIANG fuYe TANG Yong TANG Heng XI XiaoQian YANG Shu fu ting Intelligent Manufacturing Engineering Laboratory of functional Structure and Device in Guangdong School of Mechanical and Automotive EngineeringSouth China University of TechnologyGuangzhou510640China College of Mechatronics and Control Engineering Shenzhen UniversityShenzhen518000China School of Machinery and Automation Wuhan University of Science and TechnologyWuhan430000China

Aluminum-based microgroove surfaces with reentrant cavities (MSRCs) were fabricated by two staggered ploughing/extrusion processes to meet the requirements of lightweight phase change heat transfer *** MSRCs with different stagger angles between cavities and microgrooves (MGs) were fabricated to study the effect of stagger angle on capillary *** rise and permeability tests were performed on all MSRCs and the results were compared with MGs having the same processing *** was found that MSRCs with smaller stagger angles have higher capillary height,and the maximum enhancement maintained by MSRC45 was about 54.84%.However,MSRCs with larger stagger angles were found to have higher ***,the capillary parameter K·ΔP_(cap)was used as a comprehensive index to evaluate these ***90 and MSRC75 obtained the largest K·ΔP_(cap)values without and with the effect of gravity considered,*** all MSRCs had a higher capillary rise height than MGs,smaller stagger angles (≤60°) seriously reduced the permeability of MSRCs and even resulted in smaller K·ΔP_(cap)value than that of MGs when calculated considering the effect of ***,MSRCs with larger stagger angles (≥75°) may be the optimum wicks due to the good balance between capillary pressure and permeability.

关键词： stagger angle capillary performance microgroove structure reentrant cavities

Single-molecule DNA logic nanomachines based on origami

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Science China Chemistry 2019年第4期62卷 407-408页

作者： Yunyi Liu Xiaoxiao Hu ting fu Ruowen Wang Weihong Tan Molecular Science and Biomedicine Laboratory (MBL) State Key Laboratory of Chemo/Biosensing and Chemometrics College of BiologyCollege of Chemistry and Chemical Engineering Aptamer Engineering Center of Hunan Province Hunan University Institute of Molecular Medicine (IMM) Renji Hospital Shanghai Jiao Tong University School of Medicine and College of Chemistry and Chemical Engineering Shanghai Jiao Tong University Department of Chemistry and Department of Physiology and functional Genomics Center for Research at the Bio/Nano Interface Health Cancer Center UF Genetics Institute McKnight Brain Institute University of Florida

Nowadays,it is a truism that chemists,bioengineers and others must be schooled in cell and molecular biology,including knowledge of the cellular,elemental and molecular building blocks of living *** by exquisite and efficient biomolecular machines in living cells,such as ATPases that catalyze the decomposition of ATP into ADP and free phosphate ion,researchers representing multiple disciplines are actively engaged in developing artificial nanostructures with well-defined geometry and nanoscale addressability.A successful outcome of these studies could lead to the development and clinical application of smart molecular machines for the drug delivery of theranostics in vivo.

关键词： Single-molecule DNA logic nanomachines origami