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Comparison of five video-assisted intubation devices by novice and expert laryngoscopists for use in the aeromedical evacuation environment

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Military Medical Research 2017年第2期4卷 61-69页

作者： Matthew C.Wallace SSgt Tyler Britton Robbie Meek Sharon Walsh-Hart Col Todd e.Carter Steven J.Lisco University of Cincinnati Medical Center Department of Anesthesiology

Background: The critically ill or injured patient undergoing military medical evacuation may require emergent intubation. Intubation may be life-saving, but it carries *** novice or infrequent laryngoscopist has a distinct disadvantage because experience is critical for the rapid and safe establishment of a secured airway. This challenge is compounded by the austere environment of the back of an aircraft under blackout conditions. This study determined which of five different video-assisted intubation devices(VAIDs) was best suited for in-flight use by U.S. Air Force Critical Care Air Transport Teams by comparing time to successful intubation between novice and expert laryngoscopists under three conditions, Normal Airway Lights on(NAL), Difficult Airway Lights on(DAL) and Difficult Airway Blackout(DAB), using manikins on a standard military transport stanchion and the floor with a minimal amount of setup time and extraneous light ***: A convenience sample size of 40 participants(24 novices and 16 experts) attempted intubation with each of the 5 different video laryngoscopic devices on high-fidelity airway manikins. Time to tracheal intubation and number of optimization maneuvers used were recorded. kruskal-Wallis testing determined significant differences between the VAIDs in time to intubation for each particular scenario. Devices with significant differences underwent pair-wise comparison testing using rank-sum analysis to further clarify the difference. Device assembly times, startup times and the amount of light emitted were recorded. Perceived ease of use was surveyed. Results: Novices were fastest with the Pentax AWS in all difficult airway scenarios. experts recorded the shortest median times consistently using 3 of the 5 devices. The AWS was superior overall in 4 of the 6 scenarios tested. experts and novices subjectively judged the Glide Scope Ranger as easiest to use. The light emitted by all the devices was less than the USAF-issued hea

关键词： simulation difficult airway novice expert military video laryngoscopy light emission

月球Mons Rmker火山高原的地质特征与演化历史:对嫦娥五号采样返回任务的启示

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月球Mons Rmker火山高原的地质特征与演化历史:对嫦娥五号采样...

LAMOST experiment for Galactic Understanding and exploration (LeGUe)——The survey's science plan

中国矿物岩石地球化学学会第九次全国会员代表大会暨第16届学术年会

作者：赵健楠肖龙乔乐 timothy D Glotch 黄倩中国地质大学(武汉)行星科学研究所 Department of Geosciences Stony Brook University 山东大学(威海)

中国即将发射的嫦娥五号计划着陆在月球风暴洋北部区域并实施采样返回。Mons R(u|¨)mker火山高原为该区域内最为突出的地貌特征之一。该火山高原的中心坐标为301.9°e,40.7°N,面积近4000 km。该区域内分布有大量与火山活动有关的地貌...

中国即将发射的嫦娥五号计划着陆在月球风暴洋北部区域并实施采样返回。Mons R(u|¨)mker火山高原为该区域内最为突出的地貌特征之一。该火山高原的中心坐标为301.9°e,40.7°N,面积近4000 km。该区域内分布有大量与火山活动有关的地貌,如火山穹隆、熔岩流、月溪等,对研究月球火山作用和热历史具有重要意义,一直是研究的热点。

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Research in Astronomy and Astrophysics 2012年第7期12卷 735-754页

作者： Li-Cai Deng Heidi Jo Newberg Chao Liu Jeffrey L. Carlin timothy C. Beers Li Chen Hsu-Tai Lee Carl J. Grillmair Puragra Guhathakurta] Zhan-Wen Han Jin-Liang Hou Sebastien Lepine Jing Li Xiao-Wei Liu kai-ke Pan J. A. Sellwood Bo Wang Hong-Chi Wang Fan Yang Brian Yanny Hao-Tong Zhang Yue-Yang Zhang Zheng Zheng Zi Zhu key Lab for Optical Astronomy National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China licai@*** Department of Physics Applied Physics and Astronomy Rensselaer Polytechnic Institute 1108th Street Troy NY 12180 USA National Optical Astronomy Observatory Tucson AZ 85719 USA Shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai 200030 China Institute of Astronomy and Astrophysics Academia Sinica EO. Box 23-141 Taipei 106 China University of Heidelberg Landessternwarte K6nigstuhl 12 D-69117 Heidelberg Germany Spitzer Science Center 1200 E. California Blvd. Pasadena CA 91125 USA Department of Astronomy and Astrophysics University of California Santa Cruz 1156 HighStreet Santa Cruz CA 95064 USA Yunnan Astronomical Observatory Chinese Academy of Sciences Kunming 650011 China American Museum of Natural History Central Park West at 79th Street New York NY 10024USA School of Physics and electronic Information China West Normal University Nanchong637000 China ' Department of Astronomy & kavli Institute of Astronomy and Astrophysics Peking University Beijing 100871 China Apache Point Observatory PO Box 59 Sunspot NM 88349 USA Department of Physics and Astronomy Rutgers University 136 Frelinghuysen RoadPiscataway NJ 08854-8019 USA Purple Mountain Observatory Chinese Academy of Sciences Nanjing 210008 China Fermi National Accelerator Laboratory Batavia IL 60510 USA Department of Physics and Astronomy University of Utah Salt Lake City UT 84112 USA School of Astronomy and Space Science Nanjing University Nanjing 210008 China

We describe the current plans for a spectroscopic survey of millions of stars in the Milky Way galaxy using the Guo Shou Jing Telescope （GSJT, formerly calledthe Large sky Area Multi-Object fiber Spectroscopic Telescope -- LAMOST）. The survey will obtain spectra for 2.5 million stars brighter than r 〈 19 during dark/grey time, and 5 million stars brighter than r 〈 17 or J 〈 16 on nights that are moonlit or have low transparency. The survey will begin in the fall of 2012, and will run for at least four years. The telescope＇s design constrains the optimal declination range for observations to 10~ 〈 di 〈 50~, and site conditions lead to an emphasis on stars in the direction of the Galactic anticenter. The survey is divided into three parts with different target selection strategies： disk, anticenter, and spheroid. The resulting dataset will be used to study the merger history of the Milky Way, the substructure and evolution of the disks, the nature of the first generation of stars through identification of the lowest metallicity stars, and star formation through study of open clusters and OB associations. Detailed design of the LAMOST experiment for Galactic Understanding and exploration （LeGUe） survey will be completed in summer 2012, after a review of the results of the pilot survey.

关键词： techniques: spectroscopic -Galaxy: structure - Galaxy: evolution -Galaxy: kinematics and dynamics -- Galaxy: disk -- Galaxy: halo -- spectroscopy

Biological and Molecular Components for Genetically engineering Biosensors in Plants

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BioDesign Research 2022年第1期2022卷 19-37页

作者： Yang Liu Guoliang Yuan Md MahmudulHassan Paul e.Abraham Julie C.Mitchell Daniel Jacobson Gerald A.Tuskan Arjun khakhar June Medford Cheng Zhao Chang-Jun Liu Carrie A.eckert Mitchel J.Doktycz timothy J.Tschaplinski Xiaohan Yang Biosciences Division Oak Ridge National LaboratoryOak RidgeTennessee37831USA The Center for Bioenergy Innovation Oak Ridge National LaboratoryOak RidgeTennessee37831USA Department of Genetics and Plant Breeding Patuakhali Science and Technology UniversityDumkiPatuakhali8602Bangladesh Departmentof Biology Colorado State UniversityFort CollinsColorado80523USA Shenzhen Branch Guangdong Laboratory for Lingnan Modern AgricultureKey Laboratory of Synthetic BiologyMinistry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese A cademy of Agriculural SciencesShenzhen 518120China Biology Department Brookhaven National LaboratoryUptonNew York 11973USA

Plants adapt to their changing environments by sensing and responding to physical,biological,and chemical *** to their sessile lifestyles,plants experience a vast array of external stimuli and selectively perceive and respond to specific *** repurposing the logic circuitry and biological and molecular components used by plants in nature,genetically encoded plant-based biosensors(GePBs)have been developed by directing signal recognition mechanisms into carefully assembled outcomes that are easily *** allow for in vivo monitoring of biological processes in plants to facilitate basic studies of plant growth and *** are also useful for environmental monitoring,plant abiotic and biotic stress management,and accelerating design-build-test-learn cycles of plant *** the advent of synthetic biology,biological and molecular components derived from alternate natural organisms(e.g.,microbes)and/or de novo parts have been used to build *** this review,we summarize the framework for engineering different types of *** then highlight representative validated biological components for building plant-based biosensors,along with various applications of plant-based biosensors in basic and applied plant science ***,we discuss challenges and strategies for the identification and design of biological components for plant-based biosensors.

关键词： Plants Molecular monitoring

基于人工流场的四轮转向自动驾驶集成控制算法

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机械设计与研究 2022年第4期38卷 138-144页

作者：刘庆伟 GORDON Tim RAHMAN Shammi 喻凡上海交通大学机械系统与振动国家重点实验室上海200240 林肯大学工学院英国林肯LN67TS

提出了一种基于人工流场的四轮转向车辆自动驾驶路径跟踪集成控制算法。在确定的驱动、制动和侧向加速度约束下,规划了沿期望参考路径的速度轨迹。利用人工流场引导算法设计了质点模型沿参考路径的参考速度矢量生成算法,针对四轮转向车... 详细信息

提出了一种基于人工流场的四轮转向车辆自动驾驶路径跟踪集成控制算法。在确定的驱动、制动和侧向加速度约束下,规划了沿期望参考路径的速度轨迹。利用人工流场引导算法设计了质点模型沿参考路径的参考速度矢量生成算法,针对四轮转向车辆,选定前后轴的中心为控制点,并设计了前馈+反馈的底层控制算法。利用MATLAB/Simulink和CarMaker搭建了仿真环境,并设计了连续曲率变化和大曲率变化两种典型工况,验证了所提出的控制算法的有效性。试验结果表明,在质心侧向加速度0.6g的极限工况下,控制算法可实现侧向跟踪误差和偏航角误差分别小于5 cm和4°。

关键词：自动驾驶路径跟踪车辆动力学集成控制

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PNAS:维生素A和C如何擦除细胞记忆?

现代生物医学进展 2017年第4期17卷 I0003-I0003页

作者： timothy Alexander Hore[a],[b], Ferdinand von Meyenn[a], Mirunalini Ravichandran[c], Martin Bachman[d],[e] Gabriella Ficz[f] David Oxley[g] Fátima Santos[a] Shankar Balasubramanian[d],[e] Tomasz P. Jurkowski[c], Wolf Reik[a],[h], [a]epigenetics Programme Babraham Institute Cambridge CB22 3AT United Kingdom [b]Department of Anatomy University of Otago Dunedin 9016 New Zealand [c]Institute of Biochemistry University of Stuttgart 70569 Stuttgart Germany [d]Department of Chemistry University of Cambridge Cambridge CB2 1EW United Kingdom [e]Cancer Research Uk Cambridge Institute University of Cambridge Cambridge CB2 0RE United Kingdom [f]Barts Cancer Institute Queen Mary University of London London EC1M 6BQ United Kingdom [g]Mass Spectrometry Facility Babraham Institute Cambridge CB22 3AT United Kingdom [h]Wellcome Trust Sanger Institute Hinxton CB10 1SA United Kingdom

维生素A和C不只是对我们的健康有益，其还会影响到机体的DNA，日前一项刊登于国际杂志PNAS上的研究论文中，来自巴布拉汉研究所（Babraham Institute）等机构的研究人员通过研究揭示了维生素A和C如何修饰细胞的表观遗传记忆。相关研究... 详细信息

维生素A和C不只是对我们的健康有益，其还会影响到机体的DNA，日前一项刊登于国际杂志PNAS上的研究论文中，来自巴布拉汉研究所（Babraham Institute）等机构的研究人员通过研究揭示了维生素A和C如何修饰细胞的表观遗传记忆。相关研究或为后期研究者们开发新型再生医学疗法或者对细胞重编程提供一定的思路。

关键词：维生素A 细胞记忆擦除研究论文表观遗传研究人员再生医学

An algorithm for preferential selection of spectroscopic targets in LeGUe

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Research in Astronomy and Astrophysics 2012年第7期12卷 755-771页

作者： Jeffrey L. Carlin Sebastien Lepine Heidi Jo Newberg Li-Cai Deng timothy C. Beers Yu-Qin Chen Norbert Christlie Xiao-Ting Fu Shuang Gao Carl J. Grillmair PuragraGuhathakurta Zhan-Wen Han Jin-Liang Hou Hsu-Tai Lee Jing Li Chao Liu Xiao-Wei Liu kai-ke Pan J. A. Sellwood Hong-Chi Wang Fan Yang Brian Yanny Yue-Yang Zhan Zheng Zheng Zi Zhu Department of Physics Applied Physics and Astronomy Rensselaer Polytechnic Institute 110 8th Street Troy NY 12180 USA carlij@rpi.edu Department of Astrophysics American Museum of Natural History Central Park West at 79thStreet New York NY 10024 USA City University of New York 365 Fifth Avenue New York NY 10016 USA National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China National Optical Astronomy Observatory Tucson AZ 85719 USA Center for Astronomy University of Heidelberg Landesstemwarte Ktinigstuhl 12 D-69117Heidelberg Germany Spitzer Science Center 1200 E. California Blvd. Pasadena CA 91125 USA JCO/Lick Observatory Department of Astronomy and Astrophysics University of CaliforniaSanta Cruz CA 95064 USA Yunnan Astronomical Observatory Chinese Academy of Sciences Kunming 650011 China Shanghai Astronomical Observatory Chinese Academy of Sciences Shanglai 200030 China Institute of Astronomy and Astrophysics Academia Sinica EO. Box 23-141 Taipei 106 China Department of Astronomy & kavli institute of Astronomy and Astrophysics Peking UniversityBeijing 100875 China Apache Point Observatory PO Box 59 Sunspot NM 88349 USA Department of Physics and Astronomy Rutgers University 136 Frelinghuysen RoadPiscataway NJ 08854-8019 USA Purple Mountain Observatory Chinese Academy of Sciences Nanjing 210008 China Fermi National Accelerator Laboratory EO. Box 500 Batavia IL 60510 USA Department of Physics and Astronomy University of Utah Salt Lake City UT 84112 USA Department of Astronomy Nanjing University Nanjing 210011 China

We describe a general target selection algorithm that is applicable to any survey in which the number of available candidates is much larger than the number of objects to be observed. This routine aims to achieve a balance between a smoothly- varying, well-understood selection function and the desire to preferentially select cer- tain types of targets. Some target-selection examples are shown that illustrate differentpossibilities of emphasis functions. Although it is generally applicable, the algorithm was developed specifically for the LAMOST experiment for Galactic Understanding and exploration （LeGUe） survey that will be carried out using the Chinese Guo Shou Jing Telescope. In particular, this algorithm was designed for the portion of LeGUe targeting the Galactic halo, in which we attempt to balance a variety of science goals that require stars at fainter magnitudes than can be completely sampled by LAMOST. This algorithm has been implemented for the halo portion of the LAMOST pilot sur- vey, which began in October 2011.

关键词： surveys: LAMOST -- Galaxy: halo -- techniques: spectroscopic

参与式渭南地震情景构建:中国地震风险对策的行动研究示范

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地震地质 2020年第6期42卷 1446-1473页

作者：苏桂武 Janise Rodgers 田青齐文华 Philip england timothy Sim John Young 王东明李志强冯希杰孙磊陈鲲 emily So Barry Parsons 赵金礼石建梁袁志祥 Yue Cao 周旗魏本勇 David Milledge Alexander Densmore 中国地震局地质研究所北京100029 美国国际地灾美国门洛帕克94025 北京师范大学环境教育学部北京100875 牛津大学地球科学系英国牛津OX13AN 香港理工大学应用社会学系中国香港999077 国际科学理事会(ICSU)科学与政策促进国际网络(INASP) 英国牛津OX41JE 中国地震灾害防御中心北京100029 中国地震台网中心北京100045 陕西省地震局西安710068 清华大学公共管理学院/清华大学应急管理研究基地北京100084 中国地震局地球物理研究所北京100081 剑桥大学建筑学系英国剑桥CB21PX 英国海外发展研究所英国伦敦SE18NJ 宝鸡文理学院陕西省灾害监测与机理模拟重点实验室宝鸡721013 纽卡斯尔大学英国纽卡斯尔NE17RU 杜伦大学英国杜伦DH 13LE

中国政府层面自上而下的防震减灾管理卓有成效;但是,对于提升全社会的整体防震减灾能力而言,尚需推动基于此而又有民众与基层自下而上广泛参与的全社会治理模式。为发展这种模式积累经验,渭南市地震情景构建示范项目借助参与式行动研究... 详细信息

中国政府层面自上而下的防震减灾管理卓有成效;但是,对于提升全社会的整体防震减灾能力而言,尚需推动基于此而又有民众与基层自下而上广泛参与的全社会治理模式。为发展这种模式积累经验,渭南市地震情景构建示范项目借助参与式行动研究范式,特别关注了中国防震减灾工作当前存在的以下2点广泛不足:一是社会民众与基层的自下而上办法薄弱,且与政府层面自上而下对策之间的相互衔接与促进不足;二是科学研究向实际减灾对策的转化不足,特别是针对自下而上办法的科学研究与应用转化不足。取得的主要进展有:1)基于广泛参与理念,通过"研究者"和"减灾实践者"、"相关者"、"当事人"2方面人员间的密切合作,共同诊断评估了渭南面临的主要地震灾害风险及隐患、共同提炼了针对性的减灾对策改进建议等,从而使情景构建所得的结果或认识更加可靠、所提对策建议更加符合当地实际需要;借助行动研究过程平台,尝试了风险评估、风险沟通和风险对策改进3大环节的无缝衔接与同步互动,促进了科学研究与实际应用的直接对接与就地转化。2)基于多尺度、多层面视角和同时为"政府"或"部门"与"基层"或"民众"两大类用户服务。在关注改进自上而下对策的同时,针对薄弱的自下而上办法,特别是就这两大对策途径间最广泛与最可持续的接口——宣传教育和家庭、学校、社区减灾,开展了大规模的专项调查分析,梳理了系列化的现今本底与改进方向。3)聚焦改善减灾宣教和促进风险沟通,编创了由"故事"引导的2版内容与形式均有显著差别的地震情景叙事读本:政府版和公众版,以期借助"故事"和艺术呈现"故事"带动人们更好地理解与应用情景构建结果和认识,借助"故事"演绎社会性灾害脆弱成分——"留守儿童家庭与贫困"之于灾害的强化与叠加效应,促进人们对地震灾害风险更加全面与深入的认识;在理性刻板科学中融入感性与人文艺术情怀,以引导共识与共鸣、改善减灾态度、培养减灾价值观,进而激发减灾行动和减灾参与意愿,特别是激励人们就相关问题进行长期思考和持续行动改善。以上3方面进展,从总体上实现了对中国防震减灾工作存在的前述2点广泛不足的有益研讨与部分弥补推动尝试。参与式渭南地震情景构建行动研究示范,对国内相关工作具有抛砖引玉的作用,也为国际同类工作积累了中国经验。

关键词：地震情景参与式行动研究讲故事自上而下对策与自下而上办法风险评估与风险对策

early-diverging fungal phyla:taxonomy,species concept,ecology,distribution,anthropogenic impact,and novel phylogenetic proposals

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Fungal Diversity 2021年第4期109卷 59-98页

作者： kerstin Voigt timothy Y.James Paul M.kirk AndréL.C.M.de A.Santiago Bruce Waldman Gareth W.Griffith Minjie Fu Renate Radek Jürgen F.H.Strassert Christian Wurzbacher Gustavo Henrique Jerônimo David R.Simmons kensuke Seto eleni Gentekaki Vedprakash G.Hurdeal kevin D.Hyde Thuong T.T.Nguyen Hyang Burm Lee Jena Microbial Resource Collection Leibniz Institute for Natural Product Research and Infection BiologyAdolf-Reichwein-Straße 2307745 JenaGermany Institute of Microbiology Faculty of Biological SciencesFriedrich Schiller University JenaNeugasse 2507743 JenaGermany Department of ecology and evolutionary Biology University of MichiganAnn ArborMI 48109USA Biodiversity Informatics and Spatial Analysis Jodrell LaboratoryRoyal Botanic Gardens KewSurrey TW93DSUK Department of Mycology Federal University of PernambucoAv.Da Engenharias/nRecifePE 50740-4600Brazil School of Biological Sciences Seoul National UniversitySeoul 08826South Korea Department of Integrative Biology Oklahoma State UniversityStillwaterOK 74078USA Institute of Biological Environmentaland Rural Sciences(IBERS)Aberystwyth UniversityAberystwyth SY233DDWalesUK Institute of Biology/Zoology Evolutionary BiologyFreie Universität Berlin14195 BerlinGermany Leibniz Institute of Freshwater ecology and Inland Fisheries Ecosystem Research12587 BerlinGermany Department of Civil Geo and Environmental EngineeringTechnical University of MunichGarchingGermany School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Center of excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand environmental Microbiology Lab Department of Agricultural Biological ChemistryCollege of Agriculture&Life SciencesChonnam National UniversityGwangju 61186South Korea

The increasing number of new fungal species described from all over the world along with the use of genetics to define taxa,has dramatically changed the classification system of early-diverging fungi over the past several *** number of phyla established for non-Dikarya fungi has increased from 2 to ***,to date,both the classification and phylogeny of the basal fungi are still *** this article,we review the recent taxonomy of the basal fungi and re-evaluate the relationships among early-diverging lineages of fungal *** also provide information on the ecology and distribu-tion in Mucoromycota and highlight the impact of chytrids on amphibian *** concepts in Chytridiomycota,Aphelidiomycota,Rozellomycota,Neocallimastigomycota are discussed in this *** preserve the current application of the genus Nephridiophaga(Chytridiomycota:Nephridiophagales),a new type species,Nephridiophaga blattellae,is proposed.

关键词： early-diverging fungi evolution Nuclear large subunit(LSU/28S) Nuclear small subunit(SSU/18S) Molecular phylogeny