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An ultra-compact particle size analyser using a CMOS image sensor and machine learning

Light(Science & Applications) 2020年第1期9卷 1809-1819页

作者： Rubaiya Hussain Mehmet Alican noyan Getinet Woyessa Rodrigo R.Retamal Marin Pedro Antonio Martinez Faiz M.Mahdi Vittoria Finazzi Thomas A.Hazlehurst timothy n.hunter Tomeu Coll Michael Stintz Frans Muller Georgios Chalkias Valerio Pruneri ICFO-Institut de Ciencies Fotoniques The Barcelona Institute of Science and Technology08860 Castelldefels(Barcelona)Spain Ipsumio B.V. High Tech Campus5656 AEEindhovenNetherlands Department of Photonics Engineering Technical University of DenmarkDK-2800 Kgs LyngbyDenmark Research Group Mechanical Process Engineering Institute of Process Engineering and Environmental TechnologyTechnische Universitat DresdenMunchner Platz 3D-01062 DresdenGermany School of Chemical and Process Engineering University of LeedsLeeds LS29JTUK IRIS Technology Solutions SL08860 Castelldefels(Barcelona)Spain ICREA-Institucio Catalana de Recerca i Estudis Avançats 08010 BarcelonaSpain

Light scattering is a fundamental property that can be exploited to create essential devices such as particle *** most common particle size analyser relies on measuring the angle-dependent diffracted light from a sample illuminated by a laser *** to other non-light-based counterparts,such a laser diffraction scheme offers precision,but it does so at the expense of size,complexity and *** this paper,we introduce the concept of a new particle size analyser in a collimated beam configuration using a consumer electronic camera and machine *** key novelty is a small form factor angular spatial filter that allows for the collection of light scattered by the particles up to predefined discrete *** filter is combined with a light-emitting diode and a complementary metal-oxide-semiconductor image sensor array to acquire angularly resolved scattering *** these images,a machine learning model predicts the volume median diameter of the *** validate the proposed device,glass beads with diameters ranging from 13 to 125μm were measured in suspension at several *** were able to correct for multiple scattering effects and predict the particle size with mean absolute percentage errors of 5.09% and 2.5% for the cases without and with concentration as an input parameter,*** only spherical particles were analysed,the former error was significantly reduced(0.72%).Given that it is compact(on the order of ten cm)and built with low-cost consumer electronics,the newly designed particle size analyser has significant potential for use outside a standard laboratory,for example,in online and in-line industrial process monitoring.

关键词： particle size angular

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Dynamic and electrical responses of a curved sandwich beam with glass reinforced laminate layers and a pliable core in the presence of a piezoelectric layer under low-velocity impact

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Applied Mathematics and Mechanics(English Edition) 2024年第1期45卷 155-178页

作者： n.SHAHVEISI S.FELI Department of Mechanical Engineering Razi UniversityKermanshah ***Iran

The dynamic responses and generated voltage in a curved sandwich beam with glass reinforced laminate(GRL)layers and a pliable core in the presence of a piezoelectric layer under low-velocity impact(LVI)are *** current study aims to carry out a dynamic analysis on the sandwich beam when the impactor hits the top face sheet with an initial *** the layer analysis,the high-order shear deformation theory(HSDT)and Frostig's second model for the displacement fields of the core layer are *** classical non-adhesive elastic contact theory and hunter's principle are used to calculate the dynamic responses in terms of *** order to validate the analytical method,the outcomes of the current investigation are compared with those gained by the experimental tests carried out by other researchers for a rectangular composite plate subject to the *** element(FE)simulations are conducted by means of the ABAQUS *** effects of the parameters such as foam modulus,layer material,fiber angle,impactor mass,and its velocity on the generated voltage are reviewed.

关键词： analytical model piezoelectric layer curved sandwich beam glass reinforced laminate(GRL) pliable core low-velocity impact(LVI) classical non-adhesive elastic contact theory

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Morphological and molecular examination of the ciliate family Lagynusidae(Protista,Ciliophora,Prostomatea)with descriptions of two new genera and two new species from China

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Marine Life Science & Technology 2023年第2期5卷 178-195页

作者： Limin Jiang Congcong Wang Saleh A.Al-Farraj hunter n.Hines Xiaozhong Hu College of Fisheries and Key Laboratory of MaricultureMinistry of EducationOcean University of ChinaQingdao 266003China Institute of Evolution and Marine Biodiversity Ocean University of ChinaQingdao 266003China Department of Zoology College of ScienceKing Saud UniversityRiyadh 11451Saudi Arabia Harbor Branch Oceanographic Institute Florida Atlantic UniversityFort PierceFL 34982USA

Ciliates in the class Prostomatea play an important role in the global microbial loop due to their signifcant abundances and broad feeding strategies at the foundation of food *** their importance in ecosystems,the taxonomy and systematics of this group of ciliates has long been poorly understood,with this being especially true for members of the family *** we examine four lagynusids collected from sandy beaches in China,using silver-staining and 18S rRnA gene sequencing *** investigations revealed two new genera and two new species and provided details for two little known forms:Penardella marina ***.,***.,Apolagynus cucumis(as reported by Penard.Études sur les infusoires d’eau *** and Cie,Genève,1922)***.,***.,Lagynus minutus ***.,and Lagynus elegans(Engelmann in Z Wiss Zool 11:347-393,1862)Quennerstedt(Acta Univ Lund 4:1-48,1867).Penardella *** be morphologically distinguished by having more than three dikinetidal perioral *** *** from the closely related genus Lagynus in the absence of a conspicuous neck-like *** ciliature of Apolagynus cucumis is revealed here for the frst time,which demonstrates the classifcation of this species within ***,Apolagynus binucleatus(Jiang et al.,2021)*** established according to the new *** results of our phylogenetic analyses based on the 18S rRnA gene support the establishment of two new genera and indicate that Lagynusidae is monophyletic,which further strengthens its valid taxonomic status.

关键词： Ciliate Morphology new genus new species Phylogeny 18S rRnA gene

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Engineering platelet-mimicking drug delivery vehicles

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Frontiers of Chemical Science and Engineering 2017年第4期11卷 624-632页

作者： Quanyin Hu hunter n. Bomba Zhen Gu . Joint Department of Biomedical Engineering University of North Carolina at Chapel Hill and North Carolina State University NC 27695 USA.. Division of Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery Eshelman School of Pharmacy University of North Carolina at Chapel Hill NC 27599 USA.. Department of Medicine University of North Carolina School of Medicine NC 27599 USA

Platelets dynamically participate in various physiological processes, including wound repair, bacterial clearance, immune response, and tumor metastasis. Recreating the specific biological features of platelets by mimicking the structure of the platelet or translocating the platelet membrane to synthetic particles holds great promise in disease treatment. This review highlights recent advancements made in the platelet-mimicking strategies. The future opportunities and translational challenges are also discussed.

关键词： drug delivery platelets nanomedicine,bio-inspired biomimetic

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Rural implementation of the perioperative surgical home:A case-control study

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World Journal of Orthopedics 2023年第3期14卷 123-135页

作者： Srinivasan Sridhar Amy Mouat-hunter Bernadette McCrory Center for Health Outcomes and Policy Evaluation College of Public HealthThe Ohio State UniversityColumbusOH 43210United States Preanesthesia Clinic Bozeman HealthBozemanMT 59715United States Mechanical and Industrial Engineering Montana State UniversityBozemanMT 59715United States

BACKGROUnD Perioperative surgical home(PSH)is a novel patient-centric surgical system developed by American Society of Anesthesiologist to improve outcomes and patient *** has proven success in large urban health centers by reducing surgery cancellation,operating room time,length of stay(LOS),and readmission ***,only limited studies have assessed the impact of PSH on surgical outcomes in rural *** To evaluate the newly implemented PSH system at a community hospital by comparing the surgical outcomes using a longitudinal case-control *** The research study was conducted at an 83-bed,licensed level-III trauma rural community hospital.A total of 3096 TJR procedures were collected retrospectively between January 2016 and December 2021 and were categorized as PSH and non-PSH cohorts(n=2305).To evaluate the importance of PSH in the rural surgical system,a case-control study was performed to compare TJR surgical outcomes(LOS,discharge disposition,and 90-d readmission)of the PSH cohort against two control cohorts[Control-1 PSH(C1-PSH)(n=1413)and Control-2 PSH(C2-PSH)(n=892)].Statistical tests including Chi-square test or Fischer’s exact test were performed for categorical variables and Mann-Whitney test or Student’s t-test were performed for continuous *** general linear models(Poisson regression and binomial logistic regression)were performed to fit adjusted *** The LOS was significantly shorter in PSH cohort compared to two control cohorts(median PSH=34 h,C1-PSH=53 h,C2-PSH=35 h)(P valuentages of discharges to other facilities(PSH=3.5%,C1-PSH=15.5%,C2-PSH=6.7%)(P valueno statistical difference observed in 90-d readmission between control and PSH ***,the PSH implementation reduced the 90-d readmission percentage(PSH=4.7%,C1-PSH=6.1%,C2-PSH=3.6%)lower than the national average 30-d readmission percentage which is 5.5%.The PSH system was effecti

关键词： Perioperative surgical home Rural medicine Case-control study Total joint replacements Health equity

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SFRP4 expression correlates with epithelial mesenchymal transitionlinked genes and poor overall survival in colon cancer patients

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World Journal of Gastrointestinal Oncology 2019年第8期11卷 589-598页

作者： Landry E nfonsam Jana Jandova hunter C Jecius Pamela n Omesiete Valentine n nfonsam Department of Genetics Children’s Hospital of Eastern OntarioOttawaOntario K1H 8L1Canada Department of Surgery University of ArizonaTucsonAZ 85724United States

BACKGROUnD Colon cancer is among the most commonly diagnosed cancers in the United States with an estimated 97220 new cases expected by the end of *** affects 1.2 million people around the world and is responsible for about 0.6 million deaths every *** decline in overall incidence and mortality over the past 30 years,there continues to be an alarming rise in early-onset colon cancer cases(nts are often diagnosed at late stages of the disease and tend to have poor *** previously showed that the WnT“gatekeeper”gene,secreted frizzled-related protein 4(SFRP4),is over-expressed in early-onset colon ***4 is speculated to play an essential role in cancer by inhibiting the epithelial mesenchymal transition(EMT).AIM To investigate the correlation between SFRP4 expression and EMT-linked genes in colon cancer and how it affects patient *** SFRP4 expression relative to that of EMT-linked genes and survival analysis were performed using the University of California Santa Cruz Cancer Browser *** SFRP4 was found to be co-expressed with the EMT-linked markers CDH2,Fn1,VIM,TWIST1,TWIST2,SnAI1,SnAI2,ZEB1,ZEB2,POSTn,MMP2,MMP7,MMP9,and ***4 expression negatively correlated with the EMTlinked suppressors CLDn4,CLDn7,TJP3,MUC1,and *** expression of SFRP4 and the EMT-linked markers was higher in mesenchymal-like samples compared to epithelial-like samples which potentially implicates SFRP4-EMT mechanism in colon ***,patients overexpressing SFRP4 presented with poor overall survival(P=0.0293).COnCLUSIOn Considering the implication of SFRP4 in early-onset colon cancer,particularly in the context of EMT,tumor metastasis,and invasion,and the effect of increased expression on colon cancer patient survival,SFRP4 might be a potential biomarker for early-onset colon cancer that could be targeted for diagnosis and/or disease therapy.

关键词： Secreted frizzled-related protein 4 Epithelial mesenchymal transition Colon cancer Survival

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Crop Improvement and Abiotic Stress Tolerance Promoted by Moringa Leaf Extract

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Phyton-International Journal of Experimental Botany 2022年第8期91卷 1557-1583页

作者： Md.Abir Ul Islam Juthy Abedin nupur Charles T.hunter Abdullah Al Mamun Sohag Ashaduzzaman Sagar Md.Sazzad Hossain Mona F.A.Dawood Arafat Abdel Hamed Abdel Latef Marián Brestič Md.Tahjib-UI-Arif Department of Genetics and Plant Breeding Bangladesh Agricultural UniversityMymensingh2202Bangladesh Department of Agricultural Food and Nutritional ScienceUniversity of AlbertaEdmontonAB T6G 2R3Canada Chemistry Research Unit United States Department of Agriculture-Agricultural Research ServiceGainesville32608USA Department of Biochemistry&Molecular Biology Bangladesh Agricultural UniversityMymensingh2202Bangladesh Department of Crop Botany Bangladesh Agricultural UniversityMymensingh2202Bangladesh Department of Agronomy and Haor Agriculture Sylhet Agricultural UniversitySylhet3100Bangladesh Botany and Microbiology Department Faculty of ScienceAssiut UniversityAssiut71516Egypt Botany and Microbiology Department Faculty of ScienceSouth Valley UniversityQena83523Egypt Department of Botany and Plant Physiology Czech University of Life Sciences PraguePrague16500Czech Republic Institute of Plant and Environmental Sciences Faculty of Agrobiology and Food ResourcesSlovak University of AgricultureNitra94976Slovakia

Moringa leaf extract(MLE)has been shown to promote beneficial outcomes in animals and *** is rich in amino acids,antioxidants,phytohormones,minerals,and many other bioactive compounds with nutritional and growth-promoting *** reports indicated that MLE improved abiotic stress tolerance in *** understanding of the mechanisms underlying MLE-mediated abiotic stress tolerance remains *** review summarizes the existing literature on the role of MLE in promoting plant abiotic stress acclimation *** is applied to plants in a variety of ways,including foliar spray,rooting media,and seed *** application of MLE promoted crop plant growth,photosynthesis,and yield under both nonstress and abiotic stress *** treatment reduced the severity of osmotic and oxidative stress in plants by regulating osmolyte accumulation,antioxidant synthesis,and secondary *** also improves mineral homeostasis in the presence of abiotic ***,this review describes the potential mechanisms underpinning MLEmediated stress tolerance.

关键词： Abiotic stress antioxidants biostimulant plant growth moringa extract osmotic stress oxidative stress

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Mind the “Gap”: A Comparison of the Weekly Training Loads of English Premier League Academy Soccer Players in Under 23, Under 18 and Under 16 Age-Groups

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Journal of Science in Sport and Exercise 2023年第1期5卷 34-43页

作者： Jonathan M.Taylor Jonathan L.Madden Frances hunter Ben J.Thorne Shaun J.McLaren School of Health and Life Sciences Teesside UniversityMiddlesbroughUK Leeds United Football Club LeedsUK Middlesbrough Football Club MiddlesbroughUK Hintsa Performance LondonUK Department of Sport and Exercise Sciences Durham UniversityDurhamUK

Purpose The transition into full-time training represents a key period in the development of young soccer *** we compared the weekly training loads(matches,field-,and resistance-training)of English Premier-League Academy soccer players from under-16(U16),under-18(U18)and under-23(U23)age-groups during a training *** Forty players(U16 n=13,U18 n=15 and U23 n=12)were monitored using global navigation satellite systems and differential ratings of perceived exertion(dRPE).External load metrics were total distance,high-speed running distance,[absolute:≥19.8 km/h,relative:≥87%of 30-15 final-velocity(vIFT)],sprint distance(absolute:≥25.2 km/h,relative:≥80%maximal sprint speed),and dynamic stress *** load metrics were dRPE training *** Other than relative sprint distance,overall weekly external training loads were substantially greater for U18s and U23s when compared with U16s[effect size range:1.09-1.99(moderate to large);±90%confidence limits~0.45].When compared with U16s,overall internal loads were substantially greater for U18s[0.69-0.95(moderate);±~0.40],but not *** in weekly training loads between U18s and U23s were *** Substantial differences in training loads between elite U16 players and their older counterparts,indicates the need for planned increases in training loads in anticipation of the transition into full-time training.

关键词： Team-sports RPE LTAD Individualised training Training load

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Dietary manipulation and testosterone replacement therapy may explain changes in body composition after spinal cord injury: A retrospective case report

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World Journal of Clinical Cases 2019年第17期7卷 2427-2437页

作者： Ashraf S Gorgey Robert M Lester Mina P Ghatas Sakita n Sistrun timothy Lavis Spinal Cord Injury and Disorders Service Hunter Holmes McGuire VAMCRichmondVA 23249United States Department of Physical Medicine and Rehabilitation Virginia Commonwealth UniversityRichmondVA 23249United States Bionutrition Service Center for Clinical and Translational ResearchVirginia Commonwealth UniversityRichmondVA 23249United States

BACKGROUnD Reduced level of physical activity,high-fat diet and skeletal muscle atrophy are key factors that are likely to contribute to deleterious changes in body composition and metabolic following spinal cord injury (SCI).Reduced caloric intake with lowering percentage macronutrients of fat and increasing protein intake may likely to improve body composition parameters and decrease ectopic adiposity after *** To highlight the effects of dietary manipulation and testosterone replacement therapy (TRT) on body composition after SCI METHODS A 31-year-old male with T5 SCI was administered transdermal TRT daily for 16 *** intake and percentage macronutrients were analyzed using dietary *** resonance imaging and dual-energy x-ray absorptiometry were used to measure changes in body *** Caloric intake and fat percentage were reduced by 445 kcal/d and 6.5%,*** body weight decreased by 8%,body fat decreased by 29%,and lean mass increased by 7%.Thigh subcutaneous adipose tissue cross-sectional area was reduced by 31%.COnCLUSIOn Manipulation of caloric intake,fat percentage,and protein percentage may have influenced body composition after SCI.

关键词： Spinal cord injury Diet High-protein Low-fat nutrients Basal metabolic rate Case report

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Design of two-dimensional carbon-nitride structures by tuning the nitrogen concentration

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npj Computational Materials 2020年第1期6卷 562-569页

作者： Saiyu Bu nan Yao Michelle A.hunter Debra J.Searles Qinghong Yuan State Key Laboratory of Precision Spectroscopy School of Physics and Electronic ScienceEast China Normal University3663 N.Zhongshan RoadShanghai 200062PR China Centre for Theoretical and Computational Molecular Science Australian Institute for Bioengineering and NanotechnologyThe University of QueenslandBrisbaneQLD 4072Australia College of Teacher Education East China Normal University3663 N.Zhongshan RoadShanghai 200062PR China School of Chemistry and Molecular Biosciences The University of QueenslandBrisbaneQLD 4072Australia

nitrogen-doped graphene(nG)has attracted increasing attention because its properties are significantly different to pristine graphene,making it useful for various applications in physics,chemistry,biology,and materials ***,the nGs that can currently be fabricated using most experimental methods always have low n concentrations and a mixture of n dopants,which limits the desirable physical and chemical properties.

关键词： dimensional carbon structures

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