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Incidence Risk and Independent Predictors of Prolonged Air Leak in 269 Consecutive Pulmonary Resection Patients over Nine Months: A Single-Center Retrospective Cohort Study

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Open Journal of Thoracic Surgery 2016年第4期6卷 33-46页

作者： Connie Drewbrook Samarpita Das Dorsa Mousadoust Dorsa Mousadoust Dorsa Mousadoust Basil Nasir John Yee Anna mcguire Faculty of Medicine University of British Columbia Vancouver Canada Department of Surgery Division of Thoracic Surgery University of British Columbia Vancouver Canada

Introduction: Prolonged air leak (PAL) is a common complication following pulmonary resection. It is associated with pneumonia, empyema, increased length of hospital stay and health-care costs. Intraoperative techniques have been developed to mitigate the risk of developing a PAL, but for their use to be efficient, identification of patients at risk for PAL is necessary. Aim: To determine the incidence of PAL following lobectomy and lesser pulmonary resections, risk factors for development of PALs, and the impact of PAL on hospital stay and readmission rates. Methods: The following variables were analyzed as PAL risk factors: patient characteristics of age, sex, body mass index (BMI), forced minute expiratory volume and capacity ratio (FEV1 and FEV1/FVC), diffusion capacity (DCLO), and transplant recipient status. Validated scoring systems included the Charlson Comorbidity Index (CCI), Medical Research Council (MRC) dyspnea score, and Eastern Cooperative Oncology Group (EGOC) score. Surgical factors included surgical technique, unplanned conversion from video-assisted thoracoscopic surgery (VATS) to thoracotomy, location and extent of resection, presence of adhesions, completeness of fissures, and method of fissure completion. Length of hospital stay and readmission rates were analyzed. Statistical tests performed on the data include univariate and multivariate logistic regression analyses. Results: Over the 9-month study duration there were 269 lung resections, of which 31 (11.52%) had an air leak lasting longer than 5 days. Mean length of stay in hospital was significantly longer in patients with PAL compared to the control group (13 vs 5 days, P P = 0.009), right upper lobectomy (P = 0.001), and unplanned conversion from video-assisted thoracoscopic surgery (VATS) to thoracotomy (P = 0.023). Conclusion: The incidence of PAL in our study population is similar to that found in previous studies. PAL prolongs hospital length of stay. Normal BMI, right upper lobectomy

关键词： Pulmonary Resection Air Leak Risk Factors Length of Stay Thoracic Surgery

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Establishing the Tolerability to Turkeys of Nonanoic Acid at Practical Levels of Use as a Feed Flavoring

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Open Journal of Animal Sciences 2021年第3期11卷 422-439页

作者： Maria H. L. Bento Elizabeth A. Lewis Miquel Nofrarias Borja Vilà Philip mcguire Kurt Richardson NutraSteward Pembroke Dock UK CReSA—Animal Health IRTA Bellaterra Spain Animal Nutrition IRTA Constantí Spain Anitox Wellingborough UK

Objective: Nonanoic acid (NA) is one of a series of straight-chain aliphatic alcohols, aldehydes, acids and their derivatives with a well-documented history of use as a synthetic flavoring in human food. As part of a safety evaluation of NA for use as a flavoring in animal feed, an experiment was conducted to evaluate the ability of turkeys to tolerate NA at levels relevant to practical feeding practices. Materials and Methods: A total of 594-day-old BUT Premium turkeys (300 males and 294 females) were allocated at random to 40 floor pens containing either 15 males or 13 to 15 females. Poults were fed one of 4 treatment diets in crumble (0 to 14 days) or pellet (15 to 59 days) form containing 0 (control), 100, 300 or 1000 mg NA/kg complete feed for 59 days. General health and performance were monitored for the duration of the study. At days 57 and 59 of age, blood samples were taken and birds were sacrificed and necropsied for histopathological examination of the digestive tract. Significant differences were considered at P ≤ 0.05 and near-significant trends at P ≤ 0.10. <

关键词： Turkey Flavoring Nonanoic Acid Safety

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动物神捕之猎鸥神雕

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小哥白尼（野生动物） 2018年第11期 43-45页

作者：神经猎人 Shayne mcguire

神捕档案官方大名:白头海雕江湖别称:美洲雕、美洲鹰居住地:加拿大、美国全境以及墨西哥北部。江湖印象:大型猛禽;飞行能手;美国国鸟。猎物范围:各种鱼类、体形比自身小的鸟类、啮齿类动物及腐肉。捕猎装备:敏锐的视觉和嗅觉;尖利的钩状...

神捕档案官方大名:白头海雕江湖别称:美洲雕、美洲鹰居住地:加拿大、美国全境以及墨西哥北部。江湖印象:大型猛禽;飞行能手;美国国鸟。猎物范围:各种鱼类、体形比自身小的鸟类、啮齿类动物及腐肉。捕猎装备:敏锐的视觉和嗅觉;尖利的钩状喙;长而弯曲的锋利趾爪。必杀技:高速飞翔,猛然出击,用锋利的钩爪深深地刺入猎物要害部位。特异功能:可在携带猎物的同时快速飞行;所筑巢为北美鸟类中最大的巢穴。

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A Cross-Sectional Study: Chest Tube Drainage Practice Patterns among Canadian Thoracic Surgeons Following Pulmonary Surgery

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Open Journal of Thoracic Surgery 2017年第1期7卷 14-21页

作者： Samarpita Das Kyle Grant Connie Drewbrook Dorsa Mousadoust Renelle Myers Basil Nasir John Yee Anna mcguire Faculty of Medicine University of British Columbia Vancouver Canada Division of Thoracic Surgery Vancouver Coastal Health Vancouver Canada

Background: High chest tube drainage following lung surgery is a rate-limiting step to discharge, increasing length of hospital stay. There is a paucity of evidence-based clinical research on safe maximal daily chest tube drainage prior to removal. Objectives: To describe the practice patterns of Canadian thoracic surgeons with respect to daily chest tube drainage after routine pulmonary surgery. Methods: A self-reported electronic questionnaire was administered to members of the Canadian Association of Thoracic Surgeons (CATS). Data was tabulated on the primary outcome of acceptable maximal daily pleural output prior to chest tube removal, and secondary outcomes of: years in clinical practice, academic versus community setting and rational for chest tube management. Descriptive and univariate analysis was conducted for each response by maximal daily pleural drainage category. Results: A total of 124 surveys were distributed. Response rate was 56%, with a 93% completion rate. Acceptable maximal pleural drainage among surgeons was highly variable. Rationale for tube removal was also variable, including individual clinical experiences (n = 23, 33%), evidence based guidelines (n = 18, 26%), and group practice pattern (n = 12, 17%). Academic surgeons comprised 72% of respondents. Community based surgeons were more likely to remove tubes at a lower mean volume. Years in clinical practice did not influence acceptable daily pleural drainage. Conclusion: There is great variability in post-operative management of chest tube fluid output among Canadian thoracic surgeons. Future research on this topic is warranted, with the aim of developing an evidence-based chest tube management algorithm incorporating daily chest tube drainage volumes as a key variable.

关键词： Thoracic Surgery Chest Tubes Oncology Pleural Cavity

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大气CO_2升高及气候变化对中国陆地生态系统结构与功能的制约和影响(英文)

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植物生态学报 2001年第2期25卷 175-189页

作者：潘愉德 J.M.MELILLO D.W.KICKLIGHTER 肖向明 A.D.mcguire USDAForestService TheEcosystemCenter MarineBiologicalLaboratory ComplexSystemsResearchCenter UniversityofNewHampshire U.S.GeologicalSurvey

在本项研究中 ,我们探讨了大气 CO2 加倍和气候变化条件下 ,中国陆地生态系统的结构与功能的变化。与多数研究不同的是 ,我们耦合了两个以地理空间为参照的生态系统模型 ,即生物地理模型 (KBIOME)和生物地球化学模型 (TEM) ,用此研究现... 详细信息

在本项研究中 ,我们探讨了大气 CO2 加倍和气候变化条件下 ,中国陆地生态系统的结构与功能的变化。与多数研究不同的是 ,我们耦合了两个以地理空间为参照的生态系统模型 ,即生物地理模型 (KBIOME)和生物地球化学模型 (TEM) ,用此研究现状和未来的环境下 ,中国的植被分布和年净初级生产力 (N PP)的状况 ,我们采用 3个大气环流模型 ,(GFDL - Q ,GISS和 OSU )预测的结果代表未来潜在气候变化。3个气候模型的预测都表明未来的中国将变得更温暖并总体上更湿润。耦合的模型预测中国陆地生态系统的结构与功能都将产生十分显著的变化。植被的变迁表现为 :1)中国东部森林带北移 ,温带常绿阔叶林面积扩大 ,较南的森林类型取代较北的类型 ;2 )森林和草地的总面积增加 ,这是作为取代干旱灌木林、沙漠和高山苔原的结果。年净初级生产力在大气 CO2 加倍和气候变化条件下 ,增加 30 %左右。与其它研究不同的另一点是 ,我们可以进一步区分生产力变化的原因。在所增加的生产力中 ,12 %～ 2 1%是源于生态系统的功能变化 ,即 CO2 升高和气候条件改变的直接影响 ;而 11%～ 17%是源于生态系统的结构变化 ,即由较高产的生态系统取代较低产的生态系统的结果。这项研究预测了未来中国植被和生产力潜在的变化并给出了变化的范围 ,?

关键词：生态系统模型生态系统结构功能气候变化生物地球化生物地理学

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美国的地震危险性

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防灾减灾工程学报 1995年第S1期 90-92页

作者： R.K.mcguire

1 地震危险性评定历史早期地震建筑规范的技术要求是根据Algermieecn(1969)的初步工作——总结本国最大历史烈度,而Cornell(1968)的工作则是确立了对点源的概率地震危险性分析演绎法。该方法要求定义震源,震级分布和衰减函数,然后对所... 详细信息

1 地震危险性评定历史早期地震建筑规范的技术要求是根据Algermieecn(1969)的初步工作——总结本国最大历史烈度,而Cornell(1968)的工作则是确立了对点源的概率地震危险性分析演绎法。该方法要求定义震源,震级分布和衰减函数,然后对所有可能的地震震级和距离进行积分来计算地震危险性。Merz和Cornell(1973),mcguire(1976,1978),Der Kiureghian和Aug(1977)将该方法推广到能包括非指数震级分布和断层源的研究。美国地质调查局也采纳了该演绎法,并将其应用到全国范围(Algermissen和Rerhins,1976),同时合并震源和最大震级的输入范围。mcguire(1974,1977)采用谱参数(而不是峰值运动参数)第一个示范了地震危险性方法。该方法以TAC—3(1987)模型建筑规范格式应用于全国。

关键词：地震危险性所有加速度震源运动学地震活动性地震目录北美洲美国美利坚合众国

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敏捷开发策划篇——纸上革命：游戏设计的敏捷方法学

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程序员（游戏创造） 2008年第2期 16-20页

作者： Rory mcguire 封烨（译）

敏捷宣言遵循的12个原则：1．我们最优先要做的是通过尽早的、持续的交付有价值的软件来使客户满意。2．即使到了开发的后期．也欢迎改变需求，敏捷过程利用变化来为客户创造竞争优势。

关键词：敏捷开发游戏设计方法学策划客户满意竞争优势软件

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种间竞争对同域分布田鼠种群动态的影响(英文)

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动物学报 2007年第5期53卷 800-811页

作者： Lowell L.GETZ Arpat OZGUL Madan K.OLI Joyce E.HOFMANN Betty mcguire Department of Animal Biology University of Illinois Department of Wildlife Ecology and Conservation University of Florida Illinois Natural History Survey Department of Ecology and Evolutionary Biology Cornell University

我们对美国伊利诺斯州中东部的蓝草和高草牧场共生的橙腹田鼠(Microtus ochrogaster)和草原田鼠(Microtus pennsylvanicus)开放种群进行了去除实验,以测定潜在的种间竞争。在蓝草草原,橙腹田鼠和草原田鼠的种群密度不因另一种的存在而... 详细信息

我们对美国伊利诺斯州中东部的蓝草和高草牧场共生的橙腹田鼠(Microtus ochrogaster)和草原田鼠(Microtus pennsylvanicus)开放种群进行了去除实验,以测定潜在的种间竞争。在蓝草草原,橙腹田鼠和草原田鼠的种群密度不因另一种的存在而受抑制;同时,另一种存在的情况下,相互间对月存活率、青年鼠位置的持久性生殖或迁入鼠数量没有负面影响,尽管在高草草原,草原田鼠似乎对橙腹田鼠的种群密度有强烈影响,并限制了迁入鼠的数量,但是雌橙腹田鼠的存活率、青年鼠的持久性和生殖活动的比例不因草原田鼠的存在而受影响。总之,在此研究地点,种间竞争没有对橙腹田鼠和草原田鼠共存种群的动态起到驱动作用。

关键词：田鼠橙腹田鼠草原田鼠种群统计种间竞争

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A Simple Combined Antegrade Radiological and Retrograde Endoscopic Procedure to Recanalise Fibrotic Hypopharyngo-Oesophageal Occlusions: Technical Description and Lessons from Clinical Outcome in Three Cases

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International Journal of Otolaryngology and Head & Neck Surgery 2013年第5期2卷 179-185页

作者： Mohammed S. Miah Ian A. Zealley Afshin Alijani Barry mcguire Rodney E. Mountain Suresh Mahendran Department of Anaesthesia Ninewells Hospital and University of Dundee Medical School Dundee UK Department of Otorhinolaryngology-Head & Neck Surgery Ninewells Hospital and University of Dundee Medical School Dundee UK Department of Radiology Ninewells Hospital and University of Dundee Medical School Dundee UK Department of Upper Gastrointestinal Surgery Ninewells Hospital and University of Dundee Medical School Dundee UK

Background: Complete hypopharyngo-oesophageal occlusion is a rare complication of head and neck radiotherapy and a range of other conditions. Absolute dysphagia is accompanied by aspiration and dependence on gastrostomy feeding. The condition presents a substantial management challenge. Surgical approaches to re-establish pharyngo-oesophageal continuity are varied, highly invasive and are associated with unpredictable outcomes. Minimally invasive techniques employing endoscopic and radiological techniques are emerging. This report describes a multidisciplinary approach which translates two interventional radiology techniques used in the management of central venous occlusions and biliary strictures to the management of three cases of complete hypopharyngo-oesophageal occlusion. Methods: Three cases with different underlying aetiologies had treatment initiated between 2009 and 2011. Antegrade pharyngoscopic access to the occlusions was accompanied by retrograde endoscopic access via a small gastrostomy. Luminal continuity was re-established by the interventional radiology technique of “sharp recanalisation” followed by passage of a wide bore nasogastric tube which was maintained in situ for 4-6 months, a duration of treatment analogous to that applied in the radiological management of fibrotic biliary strictures. After treatment a radiological contrast swallows examination was performed to gauge the calibre of the re-established lumen, assess functionality and to rule out aspiration. Results: Pharyngo-oesophageal continuity was re-established in all three cases on the first attempt. No complications occurred as a result of the procedures. In two cases, the excellent swallowing function was re-established, although one of these required prolonged post-treatment adjuvant interventions. In one case no swallowing function resulted, despite apparently successful re-establishment of luminal continuity. Conclusions: Complete fibrotic occlusion of the hypopharyngo-oesophagea

关键词： Hypopharynx Upper Oesophagus Fibrotic Occlusion Rendezvous Technique Pharyngo-Oesophageal Continuity

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跨越三十年的爱情长跑

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疯狂英语（阅读版） 2005年第5期 12-18页

作者： Barbara Kantrowitz Stryker mcguire 小兰

他爱她,她也爱他一故事看来似乎就这么简单,但事实却复杂得多--这甚至还得颠覆王室传统,引发宗教危机。查尔斯王储与卡米拉·帕克·鲍尔斯苦苦相恋35年,相比之下,当两人宣布即将结束爱情长跑携手共度余生时,公众对终于到来的这一天并没... 详细信息

他爱她,她也爱他一故事看来似乎就这么简单,但事实却复杂得多--这甚至还得颠覆王室传统,引发宗教危机。查尔斯王储与卡米拉·帕克·鲍尔斯苦苦相恋35年,相比之下,当两人宣布即将结束爱情长跑携手共度余生时,公众对终于到来的这一天并没有表现出太大的惊讶。

关键词：三十年长跑爱情卡米拉查尔斯宗教危机王储并没有王室

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