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Channeling the water data deluge:a system for flexible integration and analysis of hydrologic data

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International Journal of Digital Earth 2016年第3期9卷 272-299页

作者： Michael P.mcguire Martin C.Roberge Jie Lian Department of Computer and Information Sciences Towson UniversityTowsonMDUSA Department of Geography and Environmental Planning Towson UniversityTowsonMDUSA

The hydrologic cycle and understanding the relationship between rainfall and runoff is an important component of earth system science,sustainable development,and natural disasters caused by *** this in mind,the integration of digital earth data for hydrologic sciences is an important area of ***,it takes a tremendous amount of effort to perform hydrologic analysis at a large scale because the data to support such analyses are not available on a single system in an integrated format that can be easily ***,the state-of-the-art in hydrologic data integration typically uses a rigid relational database making it difficult to redesign the data model to incorporate new data *** HydroCloud system incorporates a flexible document data model to integrate precipitation and stream flow data across spatial and temporal dimensions for large-scale hydrologic *** this paper,a document database schema is presented to store the integrated data-set along with analysis tools such as web services for data access and a web interface for exploratory data *** utility of the system is demonstrated based on a scientific workflow that uses the system for both exploratory data analysis and statistical hypothesis testing.

关键词： hydrology data integration cloud-based systems NoSQL NEXRAD precipitation stream flow

FunnelCloud:a cloud-based system for exploring tornado events

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International Journal of Digital Earth 2017年第10期10卷 1030-1054页

作者： Jie Lian Michael P.mcguire Todd W.Moore Department of Computer and Information Sciences Towson UniversityTowsonMDUSA Department of Geography and Environmental Planning Towson UniversityTowsonMDUSA

Recent research has shown an increase in the number of extreme tornado outbreaks per *** characterization of the spatio-temporal pattern of tornado events is therefore a critical task in the analysis of meteorological ***,there are a large number of available meteorological datasets that can be used for such ***,much of these data are distributed across multiple websites and are not accessible in a central *** poses a significant challenge for a scientist who is interested in exploring meteorological patterns associated with tornado *** paper presents a novel system which uses cloud-based technology for integrating,storing,exploring,analyzing,and visualizing meteorological data associated with tornado *** system employs a novel NoSQL database schema and web services architecture for data integration and provides a user friendly interface that allows scientists to explore the spatio-temporal pattern of tornado ***,scientists can use this interface to analyze the relationship between different meteorological variables and properties of tornado outbreaks using a number of spatio-temporal statistical and data mining *** efficacy of the system is demonstrated on a use case centered on the analysis of climatic indicators of large spatio-temporally clustered tornado outbreaks.

关键词： tornado data warehouse cloud-based system NoSQL data integration spatio-temporal clustering web-mapping

Stem radial CO_2 conductance affects stem respiratory CO_2 fluxes in ash and birch trees

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Journal of Forestry Research 2019年第1期30卷 21-29页

作者： Xiuwei Wang Zijun Mao M.A.mcguire R.O.Teskey School of Forestry Northeast Forestry University Key Laboratory of Forest Plant Ecology of Ministry of Education Northeast Forestry University Warnell School of Forestry and Natural Resources University of Georgia

The CO_2 released from respiring cells in woody tissues of trees can contribute to one of three fluxes:efflux to the atmosphere(E_A),internal xylem sap transport flux(F_T),and storage flux(DS).Adding those fluxes together provides an estimate of actual stem respiration(R_S).We know that the relative proportion of CO_2 in those fluxes varies greatly among tree species,but we do not yet have a clear understanding of the causes for this *** possible explanation is that species differ in stem radial CO_2 conductance(g_c).A high g_c would favor the E_A pathway and a low g_cwould favor the F_***,g_chas only been measured once in situ and only in a single tree *** measured g_cusing two methods in stems of Fraxinus mandshurica Rupr.(ash)and Betula platyphylla Suk.(birch)trees in situ,along with R_S,E_A,F_T and *** radial CO_2 conductance was substantially greater in ash trees than in birch *** to that finding,in ash trees over 24 h,E_Aconstituted the entire flux of respired CO_2 ,and F_Twas negative,indicating that additional CO_2 ,probably transported from the root system via the xylem,was also diffusing into the *** ash trees,F_T was negative over the entire 24 h,and this study represents the first time that has been *** addition of xylem-transported CO_2 to E_A caused E_Ato be 9% higher than the actual R_Sover the diel measurement *** trees,which had lower g_c,also had a more commonly seen pattern,with E_A accounting for about 80% of the CO_2 released from local cell respiration and F_T accounting for the *** inorganic carbon concentration in xylem sap was also lower in ash trees than in birch trees:2.7 versus 5.3 mmol L^(-1),*** results indicate that stem CO_2 conductance could be a very useful measurement to help explain differences among species in the proportion of respired CO_2 that remains in the xylem or diffuses into the atmosphere.

关键词： Stem CO2 conductance Stem respiration Stem CO2 efflux Transport flux Stem temperature Sap flow Sap flux density

Mast cell activation syndrome-anesthetic challenges in two different clinical scenarios

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The Journal of Biomedical Research 2022年第6期36卷 435-439页

作者： Brianna Lide Shane mcguire Hong Liu Cristina Chandler Department of Anesthesiology and Pain Medicine University of California Davis HealthSacramentoCA 95817USA

Mast cell activation syndrome(MCAS)includes a group of disorders that result in the inappropriate release of inflammatory mediators from mast *** mediators can affect multiple organ systems and lead to significant morbidity,and possible *** reactions,typically in response to various nonspecific stimuli,are usually mild,they may put those with MCAS at increased risk of *** this case report,we present two clinical scenarios of MCAS,and identify possible factors triggering mast cell mediator *** also define a preoperative preventive pathway,outline anesthetic considerations,and discuss the management of immediate hypersensitivity reactions in patients with *** preoperative preparation,avoidance of triggers,and development of a plan to treat possible adverse organ responses are paramount of good outcomes.

关键词： mast cell disease mast cell activation syndrome

An augmented and interactive exhibition of an archived model for Frederick Kiesler's Endless House, 1959

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Frontiers of Architectural Research 2022年第6期11卷 993-1006页

作者： Chantelle Niblock Laura mcguire John Harding Gerd Zillner Chris Hamill Andrew Whitney School of Natural and Built Environment Queens University of BelfastNorthern IrelandBT71NNUK School of Architecture University of Hawaii at MānoaHonoluluHI96822USA School of Architecture University of ReadingReadingBerkshireRG66URUK Austrian Frederick and Lillian Kiesler Private Foundation Mariahilfer Straße1060WienAustria Hotknife Digital Media NottinghamNG13HDUK

This research explores the potential of an immersive and interactive online archive to enhance our understanding of historic architecture through the study of *** reports on implementing an augmented reality mobile application that exhibits a model for the unbuilt Endless House,1959,by Frederick Kiesler.A reflective critique,from the researcher’s point of view,and initial feedback from a small sample of architecture students,provides an insight into users’experience of the exhibition,its value as a research tool,and as an educational *** on existing technologies and established research methods,we present an alternative way of exhibiting a large-scaled model for public engagement and research collaboration between academics,archivists,and *** discuss the development of the mobile application with interactive features specifically designed for an architectural *** touches on issues associated with documenting,interpreting,and exhibiting architectural models,emphasizing accessibility,accuracy,engagement,combining 3D and 2D digital assets,and user *** was found that the interactive and immersive features of the exhibition enhanced the researchers’scope to spatially inspect the model,visually experience it,collaborate with others,and strengthen connections between the model and other examples of Kiesler’s textual and visual archival materials.

关键词： Augmented model Unbuilt architecture Frederick Kiesler Interactive exhibition Endless house

Tailoring the degradation rate of magnesium through biomedical nano-porous titanate coatings

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Journal of Magnesium and Alloys 2021年第1期9卷 336-350页

作者： Matthew D.Wadge Jamie mcguire Benjamin V.T.Hanby Reda M.Felfel Ifty Ahmed David M.Grant Advanced Materials Research Group Faculty of EngineeringUniversity of NottinghamNG72RD United Kingdom Physics Department Faculty of ScienceMansoura UniversityMansoura 35516Egyp

A novel approach was developed to reduce the corrosion rate of magnesium(Mg)metal,utilising titanate *** sputtering was used to deposit ca.500 nm titanium(Ti)coatings onto pure Mg discs,followed by hydrothermal conversion and ion exchange reactions to produce sodium and calcium titanate *** confirmed the characteristic nanoporous structure of sodium and calcium titanate,with thicknesses ranging from ca.0.8 to 1.4μ*** analysis confirmed the presence of Ti^(4+)-O,Na-O,and Ca-O bonding,whilst Raman spectroscopy demonstrated characteristic vibrational modes(such as TiO 6 octahedral vibrations)of the sodium and calcium titanate perovskite ***,corrosion studies through potentiodynamic polarisation measurements demonstrated the NB/NH CaTC samples to be superior in reducing Mg degradation,compared to other samples tested,through an increase in E_(corr)from-1.49 to-1.33 V,and the reduction in corrosion current density,i corr,from 0.31 to 0.06 mA/cm^(2)for Mg and NB/NH CaTC samples,*** was a clear trend noted for the NB/NH samples,which showed an increase in E corr to more positive values in the following order:Mg

关键词： Magnesium degradation Titanate Biodegradable Ion exchange Electrochemical corrosion Magnetron sputtering

Food Production Engineering Efficiency: A Critical Analysis of the Conventional Metrics Used in Measuring Agricultural Efficiency

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Engineering（科研） 2017年第5期9卷 427-433页

作者： Mark mcguire Bountiful Backyard Corvallis USA

An analysis is reported of conventional vs. alternative metrics used in measuring food production efficiency. Economic efficiency is driven by marketplace economics, while engineering efficiency is driven by useful energy conservation. As farming systems are optimized for maximum efficiency, how “efficiency” is defined will dictate the methods used in food production. Farming methods that are optimized in terms of economic efficiency have environmental consequences that are not inherent of engineering efficiency;however, farming methods optimized in terms of engineering efficiency have labor requirements not inherent of economic efficiency. A shift from optimizing food production in terms of economic efficiency to engineering efficiency may be necessary in order to feed a growing human population.

关键词： Efficiency Farming Agriculture Calories Energy Waste Metrics Measures

Hepatocellular carcinoma surveillance:An evidence-based approach

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World Journal of Gastroenterology 2019年第13期25卷 1550-1559页

作者： Patrick S Harris Ross M Hansen Meagan E Gray Omar I Massoud Brendan M mcguire Mohamed G Shoreibah Tinsley Harrison Internal Medicine Residency Program Department of Medicine University of Alabama at Birmingham Division of Gastroenterology and Hepatology Department of Medicine University of Alabama at Birmingham

Hepatocellular carcinoma(HCC) makes up 75%-85% of all primary liver cancers and is the fourth most common cause of cancer related death worldwide. Chronic liver disease is the most significant risk factor for HCC with 80%-90% of new cases occurring in the background of cirrhosis. Studies have shown that early diagnosis of HCC through surveillance programs improve prognosis and availability of curative therapies. All patients with cirrhosis and high-risk hepatitis B patients are at risk for HCC and should undergo surveillance. The recommended surveillance modality is abdominal ultrasound(US) given that it is cost effective and noninvasive with good sensitivity. However, US is limited in obese patients and those with non-alcoholic fatty liver disease(NAFLD). With the current obesity epidemic and rise in the prevalence of NAFLD, abdominal computed tomography or magnetic resonance imaging may be indicated as the primary screening modality in these patients. The addition of alpha-fetoprotein to a surveillance regimen is thought to improve the sensitivity of HCC *** investigation of serum biomarkers is needed. Semiannual screening is the suggested surveillance interval. Surveillance for HCC is underutilized and low adherence disproportionately affects certain demographics such as nonCaucasian race and low socioeconomic status.

关键词： Liver cancer Hepatocellular carcinoma Surveillance

Accurate nanoelectrode recording of human pluripotent stem cell-derived cardiomyocytes for assaying drugs and modeling disease

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Microsystems & Nanoengineering 2017年第1期3卷 382-388页

作者： Ziliang Carter Lin Allister F.mcguire Paul W.Burridge Elena Matsa Hsin-Ya Lou Joseph C.Wu Bianxiao Cui Department of Applied Physics Stanford UniversityStanfordCA 94305USA Department of Chemistry Stanford UniversityStanfordCA 94305USA Stanford Cardiovascular Institute Stanford UniversityStanfordCA 94305USA Department of Pharmacology and Center for Pharmacogenomics Northwestern UniversityChicagoIL 60611USA

The measurement of the electrophysiology of human pluripotent stem cell-derived cardiomyocytes is critical for their biomedical applications,from disease modeling to drug ***,a method that enables the high-throughput intracellular electrophysiology measurement of single cardiomyocytes in adherent culture is not *** address this area,we have fabricated vertical nanopillar electrodes that can record intracellular action potentials from up to 60 single beating *** access is achieved by highly localized electroporation,which allows for low impedance electrical access to the intracellular ***,we demonstrate that this method provides the accurate measurement of the shape and duration of intracellular action potentials,validated by patch clamp,and can facilitate cellular drug screening and disease modeling using human pluripotent stem *** study validates the use of nanopillar electrodes for myriad further applications of human pluripotent stem cell-derived cardiomyocytes such as cardiomyocyte maturation monitoring and electrophysiology-contractile force correlation.

关键词： cardiomyocytes drug screening electrophysiology human pluripotent stem cells multielectrode array