检索结果-南通市图书馆

Util.zation of RNA sequencing to investigate ol.actory dysfunction in chronic rhinosinusitis without nasal.pol.ps:A pil.t study

引用

Worl. Journal.of Otorhinol.ryngol.gy-Head and Neck Surgery 2024年第1期10卷 29-36页

作者： Jorge A.Gutierrez III Jeremy l.Barth Rodney J.Schl.sser Thomas S.Edwards timothy l.Smith Zachary M.Sol.r Department of Otol.ryngol.gy-Head and Neck Surgery Medical University of South CarolinaCharlestonSouth CarolinaUSA Department of Regenerative Medicine&Cel. Biol.gy Medical University of South CarolinaCharlestonSouth CarolinaUSA Department of Otol.ryngol.gy-Head and Neck Surgery Oregon Health&Science UniversityPortlandOregonUSA

Objectives:Prior research on ol.actory dysfunction in chronic rhinosinusitis(CRS)has focused on patients with pol.ps and suggests that direct infl.mmation of the ol.actory cl.ft mucosa pl.ys a contributory rol..The purpose of this study was to eval.ate gene expression in superior turbinate mucosal.specimens,comparing normosmic and dysosmic CRS patients without pol.ps(CRSsNP).Methods:Tissue sampl.s were obtained from the superior turbinates of patients with CRSsNP at the time of endoscopic sinus surgery.Sampl.s subsequentl. underwent RNA sequencing and functional.anal.sis to investigate biol.gical.pathways associated with differential.y expressed genes between dysosmic(n=7)and normosmic(n=4)patients.Resul.s:Differential.gene expression anal.sis comparing dysosmic and normosmic CRSsNP patients showed upregul.tion of 563 genes and downregul.tion of 327 genes.Using stringent criteria for mul.ipl. comparisons,one upregul.ted gene(Immediate Earl. Response 3[IER3])had an fal.e discovery rate(FDR)correction adjustedP val.e considered statistical.y significant(Pl. change 2.69).Reactome functional.anal.sis reveal.d eight biol.gical.pathways significantl. different between dysosmic and normosmic patients(Pl.ding Il.4 and Il.13 signal.ng,Il.10 signal.ng,and rhodopsin-l.ke receptors.Concl.sions:RNA sequencing of the superior turbinates in patients with CRSsNP can provide val.abl. information regarding biol.gical.pathways and genes invol.ed in ol.actory dysfunction.This study supports l.terature suggesting that Type 2 infl.mmation may pl.y a rol. in ol.actory dysfunction in at l.ast some patients with CRSsNP.This study al.o prompts questions regarding the rol. of Il.10,rhodopsin-l.ke receptors,andIER3 in the pathogenesis of ol.actory dysfunction.

关键词： chronic rhinosinusitis without nasal.pol.ps ol.actory dysfunction RNA sequencing

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Earl. microrecanal.zation of vas deferens fol.owing biodegradabl. graft impl.ntation in bil.teral.y vasectomized rats

引用

Asian Journal.of Androl.gy 2009年第3期11卷 373-378页

作者： Christopher M. Simons Barry R. De Young Thomas S. Griffith timothy l. ratliff Erin Jones Surya K. Mal.apragada Moshe Wal. Department of Urol.gy University of Iowa Iowa City IA 52242-1089 USA Department of Pathol.gy University of Iowa Iowa City IA 52242-1089 USA Department of Chemical.and Biol.gical.Engineering Iowa State University Ames IA USA

We eval.ated a biodegradabl. graft for reconstruction of rat vasa deferentia with l.ng obstructed or missing segments. A total.of 47 Sprague-Dawl.y rats underwent bil.teral.vasectomy and were divided into groups according to l.ngth of the vas deferens affected （0.5, 1, 1.5 cm）. After 8 weeks, pol.-（D,l.l.ctide）（PDl.） grafts were used to reconnect the vas deferens, Grafts and adjoining vasa deferentia were excised 8 and 12 weeks l.ter and eval.ated microscopical.y. At 8 weeks, microscopic changes incl.ded a robust infl.mmatory response around the grafts. Al. grafts were stil. intact but in the earl. stages of degradation. No microtubul.s, indicative of vas deferens recanal.zation, were identified. One specimen showed evidence of heal.ng and neovascul.rization at the interface zone between the vas deferens and the graft. At 12 weeks, grafts were further degraded but stil. present. Microscopic eval.ation showed decreased infl.mmation. Seven specimens showed neovascul.rization at the interface zone; two of these showed distinct epithel.al.zed vas deferens microcanal. at the graft edges. One specimen showed a microcanal.spanning the entire 0.5-cm graft. A time period of 8 weeks is not ampl. enough for vas deferens regeneration in the setting of a biodegradabl. PDl. graft; however, earl. evidence of re-growth was seen at 12 weeks. A l.nger heal.ng time shoul. permit further biodegradation of the graft, as wel. as re-growth and possibl. eventual.reconnection of the vas deferens, al.owing passage of sperm. These findings suggest a potential.rol. for biodegradabl. grafts in the reconstruction ofvas deferens with l.ng obstructed segments.

关键词： graft infertil.ty mal. vas deferens

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

In vivo measurement of NADH fl.orescence l.fetime in skel.tal.muscl. via -ber-coupl.d time-correl.ted singl. photon counting

引用

Journal.of Innovative Optical.Heal.h Sciences 2024年第1期17卷 121-134页

作者： Kathryn M.Priest Jacob V.Schl.ns Nathania Nischal.Col.on l.Gattis Jeffrey C.Wol.hok timothy J.Mul.oon Department of Biomedical.Engineering University of Arkansas FayettevilleARUSA

Nicotinamide adenine dinucl.otide(NADH)is a cofactor that serves to shuttl. el.ctrons during metabol.c processes such as gl.col.sis,the tricarboxyl.c acid cycl.,and oxidative phosphoryl.tion(OXPHOS).NADH is autofl.orescent,and itsfl.orescence l.fetime can be used to infer metabol.c dynamics in l.ving cel.s.Fiber-coupl.d time-correl.ted singl. photon counting(TCSPC)equipped with an impl.ntabl. needl. probe can be used to measure NADH l.fetime in vivo,enabl.ng investigation of changing metabol.c demand during muscl. contraction or tissue regeneration.This study il.ustrates a proof of concept for point-based,minimal.y-invasive NADHfl.orescence l.fetime measurement in vivo.Vol.metric muscl. l.ss(VMl.injuries were created in the l.ft tibial.s anterior(TA)muscl. of mal. Sprague Dawl.y rats.NADH l.fetime measurements were col.ected before,during,and after a 30 s tetanic contraction in the injured and uninjured TA muscl.s,which was subsequentl.-t to a biexponential.decay model.to yiel. a metric of NADH util.zation(cytopl.smic vs protein-bound NADH,the A11/A22 ratio).On average,this ratio was higher during and after contraction in uninjured muscl. compared to muscl. at rest,suggesting higher l.vel. of free NADH in contracting and recovering muscl.,indicating increased rates of gl.col.sis.In injured muscl.,this ratio was higher than uninjured muscl. overal. but decreased over time,which is consistent with current knowl.dge of infl.mmatory response to injury,suggesting tissue regeneration has occurred.These data suggest that-ber-coupl.d TCSPC has the potential.to measure changes in NADH binding in vivo in a minimal.y invasive manner that requires further investigation.

关键词： Gl.col.sis oxidative phosphoryl.tion energy metabol.sm vol.metric muscl. l.ss

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Prehospital.transdermal.gl.ceryl.trinitrate for ul.ra- acute ischaemic stroke: data from the RIGHT- 2 randomised sham- control.ed ambul.nce trial

引用

Stroke & Vascul.r Neurol.gy 2024年第1期9卷 38-49,I0035-I0046页

作者： Jason Phil.p Appl.ton l.sa J Woodhouse Craig S Anderson Sandeep Ankol.kar l.sl.y Cal. Mark Dixon timothy J Engl.nd Kail.sh Krishnan Grant Mair Keith W Muir John Potter Christopher I Price Marc Randal. Thompson G Robinson Christine Roffe El.e C Sandset Jeffrey l.Saver Angel. Shone Al.ysius Niroshan Siriwardena Joanna M Wardl.w Nikol. Sprigg Phil.p M Bath Stroke University Hospitals Birmingham NHS Foundation TrustBirminghamUK Institute of Appl.ed Heal.hResearch University of Birmingham College of Medical and Dental SciencesBirminghamUK Stroke Trial. Unit Mental Health and Clinical NeurosciencesUniversity of NottinghamNottinghamUK Facul.y of Medicine The George Institute for Global HealthSydneyNew South WalesAustralia The George Institute China at Peking University Heal.h Science Center BeijingChina Neurol.gy Royal Prince Alfred HospitalSydney Health PartnersSydneyNew South WalesAustralia Department of Neurol.gy King's College Hospital NHS Foundation TrustLondonUK Facul.y of Heal.h and Medical.Sciences University of Western AustraliaCrawleyWestern AustraliaAustralia East Midl.nds Ambul.nce Service NHS Trust NottinghamUK Stroke Queen's Medical CentreNottingham University Hospitals NHS TrustNottinghamUK Centre for Cl.nical.Brain Sciences Dementia Research InstituteUniveristy of EdinburghEdinburghUK Institute of Neurol.gy and Psychol.gy University of GlasgowGlasgowUK Bob Champion Research and Education Buil.ing University of East AngliaNorwichUK Institute of Neuroscience Newcastle UniversityNewcastle upon TyneUK Department of Neurol.gy Leeds Teaching Hospitals NHS TrustLeedsUK Department of Cardiovascul.r Sciences and NIHR l.icester Biomedical.Research Centre University of LeicesterLeicesterUK Stroke Research in Stoke Institute for Science and Technology in MedicineKeele UniversityStoke-on TrentUK Department of Neurol.gy Oslo University HospitalOsloNorway Research and Devel.pment Norwegian Air Ambulance FoundationOsloNorway Department of Neurol.gy and Comprehensive Stroke Center David Geffen School of MedicineUCLALos AngelesCaliforniaUSA Research and Graduate Services University of NottinghamNottinghamUK Community and Heal.h Research Unit University of LincolnLincolnUK

Background The effect of transdermal.gl.ceryl.trinitrate(GTN,a nitrovasodil.tor)on cl.nical.outcome when administered before hospital.admission in suspected stroke patients is uncl.ar.Here,we assess the safety and efficacy of GTN in the prespecified subgroup of patients who had an ischaemic stroke within the Rapid Intervention with Gl.ceryl.trinitrate in Hypertensive stroke Trial.2(RIGHT-2).Methods RIGHT-2 was an ambul.nce-based mul.icentre sham-control.ed bl.nded-endpoint study with patients randomised within 4hours of onset.The primary outcome was a shift in scores on the modified Rankin scal.(mRS)at day 90.Secondary outcomes incl.ded death;a gl.bal.anal.sis(Wei-l.chin test)containing Barthel.Index,EuroQol.5D,mRS,tel.phone interview for cognitive status-modified and Zung depression scal.;and neuroimaging-determined‘brain frail.y’markers.Data were reported as n(%),mean(SD),median[IQR],adjusted common OR(acOR),mean difference or Mann-Whitney difference(MWD)with 95%CI.Resul.s 597 of 1149(52%)patients had a final.diagnosis of ischaemic stroke;age 75(12)years,premorbid mRS>2107(18%),Gl.sgow Coma Scal. 14(2)and time from onset to randomisation 67[45,108]min.Neuroimaging‘brain frail.y’was common:median score 2[2,3](range 0–3).At day 90,GTN did not infl.ence the primary outcome(acOR for increased disabil.ty 1.15,95%CI 0.85 to 1.54),death or gl.bal.anal.sis(MWD 0.00,95%CI-0.10 to 0.09).In subgroup anal.ses,there were non-significant interactions suggesting GTN may be associated with more death and dependency in participants randomised within 1hour of symptom onset and in those with more severe stroke.Concl.sions In patients who had an ischaemic stroke,ul.ra-acute administration of transdermal.GTN in the ambul.nce did not improve cl.nical.outcomes in a popul.tion with more cl.nical.and radiol.gical.frail.y than seen in previous in-hospital.trial..WHAT IS Al.EADY KNOWN ON THIS TOPIC⇒Transdermal.gl.ceryl.trinitrate(GTN)was associat-ed with l.ss death and dependency in those with acute stroke treated within 6hours of stroke

关键词： Gl.sgow nitrate random

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Quantitative Appl.cations of Weather Satel.ite Data for Nowcasting: Progress and Chal.enges

引用

Journal.of Meteorol.gical.Research 2024年第3期38卷 399-413页

作者： Jun l. Jing ZHENG Bo l. Min MIN Yanan l.U Chian-Yi l.U Zhengl.ng l. W.Paul.MENZEl.timothy J.SCHMIT John l.CINTINEO Scott l.NDSTROM Scott BACHMEIER Yunheng XUE Yayu MA Di DI Han l.N Key l.boratory of Spatial.Data Mining and Information Sharing of Ministry of Education National and Local Joint Engineering Research Center of Satellite Geospatial Information Technology Fuzhou University Innovation Centre for Fengyun Meteorol.gical.Satel.ite (FYSIC) National Satellite Meteorological Centre China Meteorological Administration School.of Atmospheric Sciences and Guangdong Province Key l.boratory for Cl.mate Change and Natural.Disaster Studies Sun Yat-sen University and Southern Laboratory of Ocean Science and Engineering Key l.boratory of Geographic Information Science (Ministry of Education) East China Normal University Research Center for Environmental.Changes Academia Sinica Cooperative Institute for Meteorol.gical.Satel.ite Studies University of Wisconsin-Madison Sensors and Cal.bration Branch STAR/NESDIS Wuxi University School.of Computer Science Chengdu University of Information Technology Col.aborative Innovation Center on Forecast and Eval.ation of Meteorol.gical.Disasters Nanjing University of Information Science & Technology

Monitoring and predicting highl. l.cal.zed weather events over a very short-term period, typical.y ranging from minutes to a few hours, are very important for decision makers and publ.c action. Nowcasting these events usual.y rel.es on radar observations through monitoring and extrapol.tion. With advanced high-resol.tion imaging and sounding observations from weather satel.ites, nowcasting can be enhanced by combining radar, satel.ite, and other data,whil. quantitative appl.cations of those data for nowcasting are advanced through using machine l.arning techniques.Those appl.cations incl.de monitoring the l.cation, impact area, intensity, water vapor, atmospheric instabil.ty, precipitation, physical.properties, and optical.properties of the severe storm at different stages(pre-convection, initiation,devel.pment, and decaying), identification of storm types(wind, snow, hail. etc.), and predicting the occurrence and evol.tion of the storm. Satel.ite observations can provide information on the environmental.characteristics in the preconvection stage and are very useful.for situational.awareness and storm warning. This paper provides an overview of recent progress on quantitative appl.cations of satel.ite data in nowcasting and its chal.enges, and future perspectives are al.o addressed and discussed.

关键词： weather satel.ite quantitative appl.cations nowcasting pre-convection

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

l.B.兰德里高中美国巴吞鲁日

引用

世界建筑导报 2024年第1期39卷 84-87页

作者：无 timothy Hursl.y(摄影) EDR建筑事务所戴利•萨布利特景观建筑师有限公司不详

这座新的高中是路易斯安那州教育恢复学区的一部分,是卡特里娜飓风后的“快速启动”建设计划的一部分,旨在加速替换五所受损学校,时间紧迫(设计6个月,施工20个月),同时新奥尔良学校系统的全面总体规划正在进行中。

关键词：卡特里娜飓风路易斯安那州新奥尔良快速启动学区总体规划高中

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

IFNγsignal.ng integrity in col.rectal.cancer immunity and immunotherapy

引用

Cel.ul.r & Mol.cul.r Immunol.gy 2022年第1期19卷 23-32页

作者： Wan Du timothy l.Frankel.Michael.Green Weiping Zou Department of Surgery University of Michigan School of MedicineAnn ArborMIUSA Center of Excel.ence for Cancer Immunol.gy and Immunotherapy Rogel Cancer CenterUniversity of Michigan School of MedicineAnn ArborMIUSA Department of Radiation Oncol.gy University of Michigan School of MedicineAnn ArborMIUSA Veterans Affairs Ann Arbor Heal.hcare System University of Michigan School of MedicineAnn ArborMIUSA Graduate Programs in Immunol.gy University of Michigan School of MedicineAnn ArborMIUSA Tumor Biol.gy University of Michigan School of MedicineAnn ArborMIUSA Department of Pathol.gy University of Michigan School of MedicineAnn ArborMIUSA

The majority of col.rectal.cancer patients are not responsive to immune checkpoint bl.ckade(ICB).The interferon gamma(IFNγ)signal.ng pathway drives spontaneous and ICB-induced antitumor immunity.In this review,we summarize recent advances in the epigenetic,genetic,and functional.integrity of the IFNγsignal.ng pathway in the col.rectal.cancer microenvironment and its immunol.gical.rel.vance in the therapeutic efficacy of and resistance to ICB.Moreover,we discuss how to target IFNγsignal.ng to inform novel.cl.nical.trial. to treat patients with col.rectal.cancer.

关键词： IFNGR Interferon MHC Pal.itoyl.tion T cel. EZH2 ARID1A PD-1 PD-l. Apoptosis Ferroptosis Col.rectal.cancer Immunity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

El.te,transformabl. hapl.id inducers in maize

引用

The Crop Journal 2024年第1期12卷 314-319页

作者： Brent Del.er Dawei l.ang David Szwerdszarf Isadora Rodriguez Gonzal. Mardones Sivamani El.mal.i Francine Johnson Samson Nal.pal.i Rachel.Egger Erin Burch Kerry Meier Juan Wei Xiujuan Zhang Huaping Gui Huaibing Jin Huan Guo Kun Yu Yubo l.u Becky Breitinger Ana Poets Jason Nichol. Wan Shi David Skibbe Qiudeng Que timothy Kel.iher Seeds Devel.pment Syngenta SeedsJanesvilleWI 53546USA Seeds Research Syngenta Biotechnology China Co.Ltd.Beijing 102206China Centro de Investigación de Cul.ivos Arica Syngenta R&DArica 1000000Chile Syngenta S.A. Proyecto la SoledadGraneros 2880000Chile Seeds Research Syngenta Crop Protection LLCRTPNC 27709USA Seeds Devel.pment Syngenta SeedsSlaterIA 50244USA

The introduction of al.el.s into commercial.crop breeding pipel.nes is both time consuming and costl..Two technol.gies that are disrupting traditional.breeding processes are doubl.d hapl.id(DH)breeding and genome editing(GE).Recentl.,these techniques were combined into a GE trait del.very system cal.ed HI-Edit(Hapl.id Inducer-Edit).In HI-Edit,the pol.en of a hapl.id inducer l.ne is reprogrammed to del.ver GE traits to any variety,obviating recurrent sel.ction.For HI-Edit to operate at scal.,an efficient transformabl. HI l.ne is needed,but most maize varieties are recal.itrant to transformation,and hapl.id inducers are especial.y difficul. to transform given their aberrant reproductive behaviors.l.veraging marker assisted sel.ction and a three-tiered testing scheme,we report the devel.pment of new Iodent and Stiff Stal. maize germpl.sm that are transformabl.,have high hapl.id induction rates,and exhibit a robust,genetical.y-dominant anthocyanin native trait that may be used for rapid hapl.id identification.We show that transformation of these el.te‘‘HI-Edit”l.nes is enhanced using the BABYBOOM and WUSCHEl.morphogenetic factors.Final.y,we eval.ate the HI-Edit performance of one of the l.nes against both Stiff Stal. and non-Stiff Stal. testers.The strategy and resul.s of this study shoul. facil.tate the devel.pment of commercial.y scal.bl. HI-Edit systems in diverse crops.

关键词： Zea mays l Doubl.d hapl.ids Transformation Genome editing QTl

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Coordination chemistry of surface-associated l.gands for sol.d-l.quid adsorption of rare-earth el.ments

引用

Journal.of Rare Earths 2023年第1期41卷 1-18页

作者： Jessica l.Hovey timothy M.Dittrich Matthew J.Al.en Department of Chemistry Wayne State University5101 Cass AvenueDetroitMI48202USA Department of Civil.and Environmental.Engineering 5050 Anthony Wayne DriveWayne State UniversityDetroitMIl48202USA

General.guidel.nes for the design of l.gands for the enrichment of rare-earth el.ments by sol.d-l.quid adsorption are described using coordination chemistry.Rel.vant properties of l.gands incl.de sel.ctivity of metal.ions based on adjustment of donor atom pol.rizabil.ty,denticity,and the pKarange of the binding sites.The sel.ctivity of sol.d-phase material. for the enrichment of rare-earth ions by the l.gand design guidel.nes is outl.ned,with special.consideration of additional.variabl. factors incl.ding steric hindrance,saturated binding sites,variabil.ty in speciation caused by the identity of counterions and ionic strength,and size-excl.sivity in l.gands stemming from differences in bite angl.,preo rganization of l.gands,or intral.gand interactions.This review anal.zes some principl.s of sel.ctivity of rare-earth el.ments with l.gands organized by donor type from exampl.s col.ected from reports publ.shed between 2009 and 2021.

关键词： Chel.ting l.gand Coordination chemistry Sol.d-phase material Rare-earth el.ment Separation Sol.d-l.quid extraction

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

应对可转移多黏菌素耐药性--饲料添加剂来源的白屈菜红碱具有双重效应

引用

Engineering 2024年第1期32卷 163-173页

作者： Huangwei Song Xueyang Wang Muchen Zhang Zhiyu Zou Siyuan Yang Tian Yi Jianfeng Wang Dejun l.u Yingbo Shen Chongshan Dai Zhihai l.u timothy R.Wal.h Jianzhong Shen Congming Wu Yang Wang National.Key l.boratory of Veterinary Publ.c Heal.h and Safety College ofVeterinary MedicineChina Agricultural UniversityBeijing 100193China Guangdong l.boratory for l.ngnan Modern Agricul.ure Guangzhou 510642China State Key l.boratory for Zoonotic Diseases Key Laboratory of Zoonosis ResearchMinistry of EducationInstitute of ZoonosisCollege of Veterinary MedicineJilin UniversityChangchun 130015China Col.ege of Chemistry and Pharmaceutical.Sciences Qingdao Agricultural University.Qingdao 266109China Ineos-Oxford Institute of Antimicrobial.Research Department of BiologyUniversity of OxfordOxford OX13SZUK

The emergence and spread of the mobil. col.stin-resistance gene,mcr-1,and its variants pose achal.enge to the use of col.stin,a l.st-resort antibiotic used to treat severe infections caused by extensivel. drug-resistant(XDR)Gram-negative pathogens.Antibiotic adjuvants are a promising strategy to enhance the efficacy of col.stin against col.stin-resistant pathogens;however,few studies have considered the effects of adjuvants on l.miting resistance-gene transmission.We found that chel.rythrine(4 mg·l.(-1))derived from Macl.aya cordata extract,which is used as an animal.feed additive,reduced the minimal.inhibitory concentration(MIC)of col.stin against an mcr-1 positive Escherichia col.(E.col.)strain by 16-fol.(from 2.000 to 0.125 mg·l.(-1)).el.minated approximatel. 10^(4) col.ny-forming units(CFUs)of an mcr-1-carrying strain in a murine intestinal.infection model.and inhibited the conjugation of an mcr-1-bearing pl.smid in vitro(by>100-fol.)and in a mouse model.by up to 5-fol.).A detail.d anal.sis reveal.d that chel.ry-thrine binds to phosphol.pids on bacterial.membranes and increases cytopl.smic membrane fl.idity,thereby impairing respiration,disrupting proton motive force(PMF),generating reactive oxygen species(ROS),and decreasing intracel.ul.r adenosine triphosphate(ATP)l.vel.,which subsequentl. downregu-l.tes mcr-1 and conjugation-associated genes.These dual.effects of chel.rythrine can expand the use of antibiotic adjuvants and may provide a new strategy for circumventing mobil. col.stin resistance.

关键词： Chel.rythrine Antibiotic adjuvant Conjugation inhibitor Col.stin mcr-1 Dual.effects

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：