检索结果-南通市图书馆

Molecular Diagnosis of Sexual Differentiation Disorders in Burkina Faso

Journal of Biosciences and Medicines 2024年第3期12卷 1-15页

作者： Bazie Bapio Valérie Elvira Jean Télesphore Sawadogo Soumaïla Zohoncon Théodora Mahoukèdè Tall Ahmadou Bado Prosper Soubeiga Serge Théophile Ouattara Moussa Sorgho Abel Kiendrebeogo Touwendpoulimdé Isabelle Yonli Albert Theophane Djigma Florencia millogo/traore timongo Françoise danielle Simpore Jacques Centre National de la Recherche Scientifique et Technologique (CNRST) Institut de Recherche en Sciences de la Santé (IRSS) Ouagadougou Burkina Faso Université Joseph KI-ZERBO Unité de Formation en Sciences de la Vie et de la Terre Laboratoire de Biologie Moléculaire et de Génétique (LABIOGENE) Ouagadougou Burkina Faso Centre de Recherche Biomoléculaire Pietro Annigonie (CERBA) Ouagadougou Burkina Faso Centre Hospitalier Universitaire Régional de Ouahigouya Ouagadougou Burkina Faso Centre Hospitalier Universitaire Yalgado Ouedraogo Université Joseph Ki-Zerbo Ouagadougou Burkina Faso

Sex development anomalies represent a group of congenital pathologies in which chromosomal, gonadal and anatomical sex differentiation is atypical. The aim of our study was to use molecular biology techniques to elucidate sex in cases of anomalies of sexual differentiation in Burkina Faso. This cross-sectional study took place from March 2023 to June 2023. Oral and blood samples were collected respectively using sterile swabs and stored on Swab Kits and NUCLEIcardTM (https://***/product-ranges/nucleic-card/) were used to determine gonosome profiles. Extraction was carried out using the DNA Swap solution Kit and the DNA IQ System Kit, and a PowerPlex? 21 kit (Promega) for amplification. The Applied Biosystems 9700 thermal cycler was used for PCR followed by 36 cm capillary electrophoresis in the Applied Biosystems 3130 prism sequencer. Sequence files were analyzed using GeneMapper IDX v. 3.2 software. Seven (07) patients were registered during the study period. There were 4 cases of XX DSD or 46, XX DSD and 3 cases of XY DSD or 46, XY DSD. The median age of our patients was 16 years. Civilian sex was male in 4 cases and female in 3. The most frequent reason for consultation was micropenis in 3 cases, followed by primary amenorrhea and sex ambiguity. There were 03 cases of discrepancy between genetic sex and civil sex. The accessibility of molecular diagnosis is little known to clinicians. XX DSDs or 46, XX DSDs were the most frequent (4/7) in our study. The problem facing this situation is early diagnosis to help prevent complications in Burkina Faso.

关键词： Gonosome DSD Abnormal Sexual Development Burkina Faso

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Evaluation of the Fetal Neuroprotection Protocol with Magnesium Sulphate in a University Hospital in Burkina Faso

引用

Open Journal of Obstetrics and Gynecology 2022年第10期12卷 1042-1055页

作者： timongo francois. danielle millogo-traoré Oumarou Sawadogo S. W. Zongo-Kondé Training and Research Unit in Health Sciences Joseph Ki-Zerbo University Ouagadougou Burkina Faso Universitaire Hospitalier Yalgado Ouédraogo Ouagadougou Burkina Faso Regional Hospital Center Koudougou Burkina Faso

Introduction: Prematurity continues to stand as a major public health issue worldwide and more particularly for low incomes countries like Burkina Faso. Indeed, it is the main cause of high death rate and infant morbidity, neurologic deficiencies being one of them. Objective: From March 1st to September 30th, 2020, evaluate the fetal neuroprotection protocol using sulfate magnesium during births before thirty-three (33) weeks of amenorrhea at the University Health Centers (UHC) of Yalgado Ouedraogo and Bogodogo in Ouagadougou, Burkina Faso. Patients and Methods: It was a prospective cohort survey, exposed or unexposed. The exposed ones are from the UHC of Yalgado Ouedraogo, while the unexposed ones are from the UHC of Bogodogo. Analysis of the results showed 87 newborns from the exposed and 180 from the unexposed. The mortality rate, as well as neonatal neurologic complications, was higher with unexposed than with exposed. Although antenatal exposure to magnesium sulfate was not statistically associated with mortality and morbidity in newborns at a threshold of 0.05%, it has shown an overall good neurological prognosis in newborns exposed. Conclusion: A survey of a large sample of the population would be relevant in order to better assess the determinants of this influence. Proposition: In light of the results, the use of magnesium sulfate for neuroprotective purposes could be considered in our countries.

关键词： Premature Delivery Fetal Neuroprotection Sulfates Magnesium UHC of Yal-gado Ouedraogo UHC of Bogodogo Burkina Faso

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Evaluation of the Adequacy between the Workload and the Number of State Midwives and Maieuticians Practicing in the Gynecology-Obstetrics Departments of the University Hospitals of Burkina Faso

引用

Open Journal of Obstetrics and Gynecology 2022年第7期12卷 649-660页

作者： timongo Françoise danielle millogo-traore Pazoudba Rachida Marie Joséphine Ouedraogo-Drabo Pierre Yameogo Yalgado Ouédraogo University Hospital Ouagadougou Burkina Faso Regional University Hospital of Ouahigouya Ouahigouya Burkina Faso University Health Coverage of Burkina Faso Burkina Faso

Objective: To evaluate the adequacy between the workload and the number of midwives and state midwives practicing in the gynecology-obstetrics services of the university hospitals of Burkina Faso. Methodology: This is a multicenter study conducted in 4 university hospitals representing this country (for brevity referred here to as A, B, C, and D) from May 1, 2018, to April 30, 2019. The Workload Indicators of Staffing Need (WISN) method was used to analyze the workload. Results: Dystocic delivery was the activity that took the most time. Inpatient activities were the most performed in terms of volume. At the University Hospitals D and C, there was an over-staffing of midwives and maïeuticians with a ratio of 1.93 and 2.12 respectively. At University Hospital B, the workload was in line with the existing number of State midwives and maieuticians. A low workload pressure (04%) was found at the University Hospital A. Conclusion: In most of the University Hospital Centers, there was no match between the workload and the number of midwives and maïeuticians. These results highlight the need for redeplayment of midwives and maïeuticians in order to ensure good health coverage for midwives and maïeuticians.

关键词： Workload Midwives Maïeuticians WISN University Hospital Center Burkina Faso

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Iatrogenic Lesions of the Ureter Following Obstetric or Gynaecological Surgery Managed at Yalgado Ouedraogo University Hospital: A Series of 14 Cases

引用

Open Journal of Obstetrics and Gynecology 2018年第2期8卷 106-112页

作者： timongo francois. danielle millogo/traore Kiswendsida Bonkoungou Fasnéwindé Aristide Kabore Ali Ouedraogo Léonie Claudine Lougue/Sorgho Department of Obstetrics and Gynaecology Yalgado Ouédraogo University Hospital Ouagadougou Burkina Faso Department of Urology and Andrology Yalgado Ouédraogo University Hospital Ouagadougou Burkina Faso Department of Radiology and Imaging Charles de Gaulle University Hospital Ouagadougou Burkina Faso

Objective: To describe the aetiology, clinical presentation, management and outcomes of a series of patients with iatrogenic lesions of the ureter following obstetric or gynaecological surgery treated at Yalgado Ouedraogo University Hospital, Ouagadougou, Burkina Faso. Methods: This is a case series looking at 14 consecutive patients from 1 January 2011 to 28 February 2017, operated on for urological complications following obstetric and gynaecological surgery. Results: Our study focused on fourteen cases. The average age was 32.9 years (range 20 - 60 years). Thirteen were housewives. Eleven lived in rural areas. The aetiological factor was Caesarian section in seven cases, laparotomy in four cases and hysterectomy in three cases. The type of ureteral injury was bilateral ligation in nine cases. The average time to diagnosis was 16 days (range 2 - 120 days). Anuria was the commonest presenting symptom. Ultrasound in ten patients showed evidence of uretero-hydronephrosis. Eight patients required renal dialysis. Surgical management was uretero-vesical re-implantation in eleven cases, disunion of sutures associated with catheterization in two cases and a termino-terminal ureteral anastomosis in one case. The average hospital stay was 26 days (range 9 - 44 days). The post-operative period was complicated by two cases of vesico-vaginal fistula, one case of parietal suppuration, one case of pyelonephritis and one case of hydronephrosis. No deaths were recorded and a complete cure was ultimately obtained in all patients. Conclusion: Urological complications of obstetric and gynaecological surgery are dominated by ligation of the ureters in our setting. Caesarian section is the commonest cause. Treatment is essentially surgical.

关键词： Iatrogenic Lesion Ureter Obstetric and Gynaecological Surgery

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：