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基于产品生命周期时间维的冷链工位碳足迹模型与计算

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计算机集成制造系统 2018年第2期24卷 533-538页

作者：徐兴李仁旺吴新丽赵芸王修梓鲍森 timo nyberg 浙江科技学院机械与汽车工程学院浙江杭州310023 阿尔托大学工业工程与管理系芬兰赫尔辛基02150 浙江理工大学机械与自动控制学院浙江杭州310018 浙江科技学院信息与电子工程学院浙江杭州310023

为了计算冷链产品某个工位的碳足迹,针对冷链工位的碳排放,从时间维度出发,定义时间维的冷链碳足迹系统边界,建立基于产品生命周期时间维的冷链碳足迹模型;通过目标分析和数据收集,建立基于统计过程控制方法的碳足迹计算模型,给出单位... 详细信息

为了计算冷链产品某个工位的碳足迹,针对冷链工位的碳排放,从时间维度出发,定义时间维的冷链碳足迹系统边界,建立基于产品生命周期时间维的冷链碳足迹模型;通过目标分析和数据收集,建立基于统计过程控制方法的碳足迹计算模型,给出单位时间内冷链工位碳足迹量化的准确方法。以某冷链企业为例,计算某批次冷链产品生命周期过程中某工位的碳排放量,并验证了模型的有效性与实用性,从而实现了冷链工位全程碳足迹的分析统计。

关键词：产品生命周期时间维冷链碳足迹统计过程控制

Impact of Assimilation of radiosonde and UAV Observations from the Southern Ocean in the Polar WrF Model

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Advances in Atmospheric Sciences 2020年第5期37卷 441-454页

作者： Qizhen SUN timo VIHMA Marius OJONASSEN Zhanhai ZHANG College of Oceanic and Atmospheric Sciences Ocean University of ChinaQingdao 266100China Polar research and Forecasting Division National Marine Environmental Forecasting CenterBeijing 100081China Finnish Meteorological Institute PO Box 503Helsinki FI 00101Finland Geophysical Institute University of BergenPO Box 7803Bergen NO 5020Norway The University Centre in Svalbard PO Box 156Longyearbyen NO 9171Norway Key Laboratory for Polar Science of the State Oceanic Administration Polar Research Institute of ChinaShanghai 200136China

Weather forecasting in the Southern Ocean and Antarctica is a challenge above all due to the rarity of observations to be assimilated in numerical weather prediction(NWP)*** observations are expensive and logistically challenging,it is important to evaluate the benefit that additional observations could bring to *** soundings applying unmanned aerial vehicles(UAVs)have a large potential to supplement conventional radiosonde sounding ***,we applied UAV and radiosonde sounding observations from an rV Polarstern cruise in the ice-covered Weddell Sea in austral winter 2013 to evaluate the impact of their assimilation in the Polar version of the Weather research and Forecasting(Polar WrF)*** experiments revealed small to moderate impacts of radiosonde and UAV data *** any case,the assimilation of sounding data from both radiosondes and UAVs improved the analyses of air temperature,wind speed,and humidity at the observation site for most of the ***,the impact on the results of 5-day-long Polar WrF experiments was often felt over distances of at least 300 km from the observation *** experiments succeeded in capturing the main features of the evolution of near-surface variables,but the effects of data assimilation varied between different *** to the limited vertical extent of the UAV observations,the impact of their assimilation was limited to the lowermost 1?2-km layer,and assimilation of radiosonde data was more beneficial for modeled sea level pressure and near-surface wind speed.

关键词： numerical weather prediction radiosonde soundings unmanned aerial vehicles data assimilation Antarctic Southern Ocean

A geologically-based approach to map arsenic risk in crystalline aquifers:Analysis of the Tampere region, Finland

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Geoscience Frontiers 2019年第5期10卷 1731-1741页

作者： Daniele Pedretti Samrit Luoma timo ruskeeniemi Birgitta Backman Geological Survey of Finland (GTK) EspooFinland Dipartimento di Scienze della Terra “A. Desio” Università degli Studi di MilanoMilanItaly

The study illustrates the critical role of accurate geological structural mapping to delineate crystalline aquifer zones more prone to high health risk due to elevated dissolved As in drinking *** analysis revisits the results from more than 1200 groundwater samples collected over ten years from domestic wells across the Tampere region (Finland).It is demonstrated that the highest dissolved As concentrations in the region (up to 2230 mg/L) are exclusively found near major faults and deformation zones (FDZs) detected via geophysical and geological surveys,and that a clear correlation exists between dissolved concentrations and the distance from the FDZs (r).Almost all values exceeding the drinking water limit (10 mg/L) occur at r rations above 100 mg/L occur at r rations in bedrock show less dependency on FDZ than aqueous *** behavior is explained considering different mechanisms,which include enhanced sulfide oxidation and fracture connectivity,promoting preferential transport of dissolved As to FDZs and mixing of waters from different redox zones,mobilizing preferentially As(III) or As(V).Fe hydro-oxides may also precipitate/ dissolve preferentially because of FDZs,while residence time may influence the contact time between water and As-bearing *** is concluded that the accurate mapping of FDZs,and in general of structural geology,provides an important preliminary information to identify where localized,sitespecific characterization of hydrogeology and geochemistry is more urgent to reduce As-related health risk from groundwater intake.

关键词： Arsenic risk Crystalline bedrock Fractured aquifers Heterogeneity Finland

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造纸业的纸机视图发展趋势

经济导报（纸业技术） 2010年第2期 24-27页

作者： Pekka Hemi Nordic timo nyberg 芬兰Nordic

快速矩阵相机通过高分辨率的数据捕获能更好地控制造纸流程。

关键词：造纸业发展趋势纸机视图高分辨率运行速度流程

Association of Helicobacter pylori IgA antibodies with the risk of peptic ulcer disease and gastric cancer

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World Journal of Gastroenterology 2005年第43期11卷 6871-6874页

作者： timo U Kosunen Kari Seppl Seppo Sarna Arpo Aromaa Paul Knekt Jarmo Virtamo Anniina Salomaa-rsnen Hilpi rautelin Department of Bacteriology and Immunology Gastroenterological research Unit Department of Public Health National Public Health Institute

AIM: To compare the prevalence of Helicobacter pylori (Hpylori) IgG and IgA antibodies between adult subjects,with defined gastric diseases, nondefined gastric disorders and those representing the ***: Data on H pylori IgG and IgA antibodies,determined by enzyme immunoassay, were analyzed in 3 252 subjects with DGD including 482 patients with gastric ulcer, 882 patients with duodenal ulcer, 1 525patients with chronic gastritis only and 363 subjects with subsequent gastric cancer, 19 145 patients with NoDg and4 854 POPUL subjects. The age-adjusted prevalences were calculated for 1- and 20-year age ***: The prevalences of IgG antibodies were equally high (89-96%) in all 20-year age cohorts of the DGD groups, whereas the prevalences of IgG antibodies were lower and increased by age in the POPUL and NoDg groups. The prevalences of IgA antibodies were also higher in the DGD groups; among them CA (84-89%) and GU groups (78-91%) showed significantly higher prevalences than DU (68-77%) and CG patients (59-74%) (Or 2.49, 95%CI 1.86-3.34 between the GU and DU groups). In the CA, GU, and DU groups, the IgA prevalences showed only minor variation according to age, while they increased by age in the CG, POPUL, and NoDg groups (P≤0.0001). The IgA response, but not the IgG response, was associated with an increased risk of CA (Or 2.41, 95%CI 1.79-3.53) and GU (Or 2.57,95%CI 1.95-3.39) in comparison with CG ***: An IgA antibody response during H pylori infection is significantly more common in CA and GU patients as compared with CG patients.

关键词： Helicobacter pylori IgA antibodies Gastriccancer Gastric ulcer Duodenal ulcer Chronic gastritis

Overexpression of HSP27 and HSP70 is associated with decreased survival among patients with esophageal adenocarcinoma

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World Journal of Clinical Cases 2019年第3期7卷 260-269页

作者： Henna K S?derstr?m Juha T Kauppi Niku Oksala timo Paavonen Leena Krogerus Jari r?s?nen Tuomo rantanen Department of General Thoracic Surgery Helsinki University Central Hospital Faculty of Medicine and Life Sciences University of Tampere Department of Vascular Surgery Tampere University Hospital Department of Pathology Fimlab Laboratories and Department of Medicine and Life Sciences University of Tampere Department of Pathology Helsinki University Central Hospital Department of Surgery Kuopio University Hospital Department of Surgery Institute of Clinical Medicine University of Eastern Finland

BACKGrOUND Overexpression of heat shock proteins(HSPs) is associated with several malignancies and contributes to the development, progression, and metastasis of cancer, in addition to the inhibition of cellular death. In recent years, there has been active research into using HSP inhibitors in several malignancies. Due to the poor prognosis of esophageal adenocarcinoma(EAC), it would be valuable to find new biomarkers for the development of cancer *** To evaluate the expressions of HSP27 and HSP70 and their effect on survival in *** Immunohistochemical analyses and evaluations of HSP27 and HSP70 expression were performed on all available samples from 93 patients diagnosed with EACbetween 1990 and 2007 at two university hospitals. Fifteen cases with Barrett's metaplasia and 5 control cases from the same patient population were included in the analysis. HSP expression was quantitatively assessed and classified as high or low. Kaplan-Meier analyses and Cox regression models adjusting for age and sex as well as tumor site, stage, and grade were used to evaluate the effect on *** Tumor stage and surgical treatment were the main prognostic factors. High HSP27 expression in cancer cases was a strong negative predictive factor, with a mean survival of 23 mo compared to the 49 mo in cases with a low expression(P= 0.018). The results were similar for HSP70, with a poorer survival of 17 mo in cases with high HSP70 expression, in contrast to 40 mo(P = 0.006) in cases with a low expression. A Cox regression survival analysis was performed, adjusting for possible confounding factors, and higher HSP27 and HSP70 expressions remained an independent negative prognostic factor. The HSPs' correlation with survival was not affected by cancer treatments. When the analysis was adjusted for all factors, the odds ratios for HSP27 and HSP70 were 3.3(CI: 1.6–6.6, P =0.001) and 2.2(CI: 1.2–3.9, P = 0.02), *** HSP27 and HSP70 overexpression i

关键词： Esophageal adenocarcinoma Heat shock proteins Heat shock protein 27 Heat shock protein 70 Overexpression Survival

The ADV/ASV AATSr aerosol retrieval algorithm:current status and presentation of a full-mission AOD dataset

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International Journal of Digital Earth 2016年第6期9卷 545-561页

作者： Pekka Kolmonen Larisa Sogacheva timo H.Virtanen Gerrit de Leeuw Markku Kulmala Finnish Meteorological Institute HelsinkiFinland Department of Physics University of HelsinkiHelsinkiFinland

An advanced along-track scanning radiometer(AATSr)global multi-year aerosol retrieval algorithm is *** land,the AATSr dual-view(ADV)algorithm utilizes the measured top of the atmosphere(TOA)reflectance in both the nadir and forward views to decouple the contributions of the atmosphere and the surface to retrieve aerosol *** ocean,the AATSr single-view(ASV)algorithm minimizes the discrepancy between the measured and modelled TOA reflectances in one of the views to retrieve the aerosol information using an ocean reflectance *** steps to process global,multiyear aerosol information are *** include cloud screening,the averaging of measured reflectance,and *** of the algorithms are also *** main product of the aerosol retrieval is the aerosol optical depth(AOD)at visible/near-infrared *** retrieved AOD is validated using data from the surface-based AErONET and maritime aerosol network(MAN)sun photometer networks as *** validation shows good agreement with the reference(r=0.85,rMSE=0.09 over land;r=0.83,rMSE=0.09 at coasts and r=0.96,rMSE=0.06 over open ocean).The results of the aerosol retrievals are presented for the full AATSr mission years 2002–2012 with seasonally averaged time series for selected regions.

关键词： Visible/infrared remote sensing earth observation global environmental change atmospheric aerosols

Optical imaging of post-embryonic zebrafish using multi orientation raster scan optoacoustic mesoscopy

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Light(Science & Applications) 2016年第1期5卷 336-341页

作者： Murad Omar Johannes rebling Kai Wicker Tobias Schmitt-Manderbach Mathias Schwarz Jérôme Gateau Hérnan López-Schier timo Mappes Vasilis Ntziachristos Chair for Biological Imaging Technische Universität MünchenMünchen D-81675Germany Institute for Biological and Medical Imaging Helmholtz Zentrum MünchenNeuherberg D-85764Germany Carl Zeiss AG Corporate Research and TechnologyJena D-07745Germany ESPCI Paris PSL Research UniversityCNRSINSERMInstitut LangevinParis F-75005France research Unit Sensory Biology and Organogenesis Helmholtz Zentrum MünchenNeuherberg D-85764Germany Carl Zeiss Vision International GmbH Technology&InnovationAalen D-73430Germany

Whole-body optical imaging of post-embryonic stage model organisms is a challenging and long sought-after *** requires a combination of high-resolution performance and high-penetration ***(photoacoustic)mesoscopy holds great promise,as it penetrates deeper than optical and optoacoustic microscopy while providing high-spatial ***,optoacoustic mesoscopic techniques only offer partial visibility of oriented structures,such as blood vessels,due to a limited angular detection aperture or the use of ultrasound frequencies that yield insufficient *** introduce 3601 multi orientation(multi-projection)raster scan optoacoustic mesoscopy(MOrSOM)based on detecting an ultra-wide frequency bandwidth(up to 160 MHz)and weighted deconvolution to synthetically enlarge the angular *** report unprecedented isotropic inplane resolution at the 9–17μm range and improved signal to noise ratio in phantoms and opaque 21-day-old *** find that MOrSOM performance defines a new operational specification for optoacoustic mesoscopy of adult organisms,with possible applications in the developmental biology of adulthood and aging.

关键词： deconvolution development mesoscopy multiview optoacoustics photoacoustics

robotic surgery techniques to approach benign prostatic hyperplasia disease:A comprehensive literature review and the state of art

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Asian Journal of Urology 2021年第1期8卷 81-88页

作者： Marcio Covas Moschovas Frederico timo´teo Leonardo Lins Ose´as de Castro Neves Kulthe ramesh Seetharam Bhat Vipul r.Patel Department of robotic Surgery AdventHealth Global Robotics InstituteFLUSA Faculdade de Medicina do ABC Sa˜o PauloBrazil

Objective:The robotic-assisted approach to simple prostatectomy(rASP)was conceived,essentially reproducing the fundaments of open simple *** the first report,rASP underwent several technical *** study aims to identify and describe the current robotic surgery techniques to approach benign prostatic hyperplasia(BPH).Methods:The paper performed a non-systematic literature review accessing PubMed and Embase databases for all full-text articles published from 2008 to May 2020,assessing robot-assisted surgical techniques for BPH treatment using the terms“robot-assisted simple prostatectomy”Or“robotic simple prostatectomy”Or“rASP”AND“surgical technique”.results:After careful review of 180 studies in PubMed and 198 in Embase,16 papers reporting different rASP *** the first procedure described by Sotelo et al.[9],several authors contributed to the development of the rASP *** et al.[24]proposed the extraperitoneal access,and Yuh et al.[23]first reported the adenoma transcapsular *** modifications were proposed by Coelho et al.[31]on trigonization,posterior reconstruction,and urethro-vesical *** groups focused on urethral-preserving *** et al.[28]and Clavijo et al.[32]recently described an intrafascial rASP with the removal of the entire prostatic ***,Kaouk et al.[29]reported the feasibility and safety of the da Vinci Single Port ***:In the last eighteen years,the robotic-assisted approach to BPH disease has been evolved,and different techniques have been *** review details all the technical developments on rASP that distinctive groups have proposed since the multiport robotic platforms until the new da Vinci Single Port.

关键词： Simple prostatectomy Benign prostatic hyperplasia robotic-assisted Minimally invasive