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Nanotechnology in Cosmetics: Basics, Current Trends and Safety Concerns—A Review

Advances in Nanoparticles 2020年第1期9卷 1-22页

作者： Daniel Ekpa Effiong timma otobong uwah Edidiong Udofa Jumbo Akwaowo Elijah Akpabio Department of Pharmaceutics and Pharmaceutical Technology University of Uyo Uyo Nigeria Pharmaceutical Microbiology Unit Department of Pharmaceutics University of Uyo Uyo Nigeria Department of Clinical and Biopharmacy University of Uyo Uyo Nigeria

As nanotechnology finds new applications, the formulation and use of nano-particulate structures in the production of cosmetics and cosmeceuticals keeps increasing. Nano-sized materials such as cubosomes, nanodots, liposomes, dendrimers, nano-emulsions are now becoming regular ingredients in the cosmetic space. These nanoparticle-based cosmetics or nano-cosmeceuticals have extended the boundaries of the applications of cosmetics in managing conditions of wrinkling, dehydrated and inelastic skin associated with aging and dispersed hyperpigmentation. With so many claims by giant cosmetic manufacturers on the several possibilities achievable by such products containing these, there remain valid questions needing answers. Such includes: what are the actual facts as opposed to unfounded expectations on use of nano-materials in cosmetics? What are the peculiar properties of Nano-sized structures? Any potential or actual health risks associated with nanoparticle-incorporated cosmetic products? What roles are the regulating authorities and academic researchers playing in the light of all these developments? This review attempts to answer these questions, taking a look at the updates on nano-sized materials used in cosmetics, while presenting actual advances made in nano-cosmetics amidst the seemingly not too obvious hidden risks.

关键词： Nanotechnology Nanoparticles Cosmetics Nano-Cosmeceuticals Safety Concerns

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Eco-Friendly Synthesis of Silver Nano Particles Using <i>Carica papaya</i>Leaf Extract

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Soft Nanoscience Letters 2018年第1期8卷 1-7页

作者： Tenderwealth Clement Jackson timma Oto-Obong uwah Akeem Ayodeji Agboke Blessing Edidiong Udo Edidiong Michael Udofa Department of Pharmaceutics and Pharmaceutical Technology University of Uyo Uyo Nigeria

Silver nanoparticles were synthesized using eco-friendly method with extract of Carica papaya as reducing and stabilizing agent. The silver precursor used was silver nitrate solution. A visible colour change from colourless to reddish brown confirmed the formation of the nanoparticles and the UV-Vis spectroscopy showed surface plasmon resonance of 435 nm for the silver nanoparticle. The mean particle size was 250 nm while the polydispersity index was 0.22. The antimicrobial activity of the synthesized nanoparticles was studied against Pseudomonas aeruginosa, Escherichia coli, Bacillus subtilis and Staphylococcus aureus. The silver nanoparticles biosynthesized showed satisfactory antimicrobial activity against the test isolates. Antimicrobial property of the nanoparticles was similar (P > 0.05). Generally, MIC values of the samples against the microorganisms tested ranged from 25 - 100 mg/ml. Pseudomonas aeruginosa was most sensitive while Staphylococcus aureus and Bacillus subtilis were least sensitive to the silver nanoparticles.

关键词： Silver Nanoparticles Eco-Friendly Method Characterisation Antimicrobial

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