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Re-Os Dating of Molybdenite from the Yaogangxian Tungsten Deposit,South China,and Its Geological Significance

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Acta Geologica Sinica(English Edition) 2008年第4期82卷 820-825页

作者： WANG Yonglei PEI Rongfu LI Jinwen qu Wenjun LI Li WANG Haolin DU Andao Institute of Mineral Resources Chinese Academy of Geological Sciences Beijing 100037China National Research Center of Geoanalysis Beijing 100037 China

The Yaogangxian tungsten deposit is located in the central part of the Nanling polymetailic metallogenic province. The orebodies occur as veins. Wolframite and molybdenite are the dominant ore minerals. Two samples were selected for molybdenite Re-Os dating in order to elucidate the timing of mineralization. Re-Os datings of molybdenite from quartz-woiframite veins and disseminated in granite yield ages of 153±7 Ma and 163.2±4.2 Ma respectively. The results indicate that the Yaogangxian tungsten deposit is the product of large-scale metallogenesis in the middle Yanshanian period in South China, and that the evolution from late magmatic to postmagmatic hypothermal mineralization occurred at about 10 Ma. The rhenium content of molybdenite in the Yaogangxian tungsten deposit suggests that the ore materials originated from the crust.

关键词： Re-Os isotopes molybdenite tungsten deposit South China

A new latency-reducing and energy-efficient protocol for the wireless sensor network

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Frontiers of Electrical and Electronic Engineering in China 2007年第2期2卷 144-150页

作者： XIONG Junjie qu Yugui LIN Huahui PAN quanke ZHAO Baohua Department of Electronic Engineering and Information Science MOEMS Key Laboratory of Multimedia Calculation and CommunicationUniversity of Science and Technology of ChinaHefei 230027China

This paper introduces a new protocol routing medium access control(RMAC)that integrates the routing and medium access control(MAC)layer *** can both reduce latency and save energy in the wireless sensor network(WSN)while most others propose protocols that sacrifice latency for *** make RMAC fit WSN better,we designed an easy and efficient routing protocol base station flooding(BSF)and then integrated it with a MAC protocol timing out MAC(TMAC)[1],while traditionally BSF and TMAC work separately at two *** call this two-layer protocol(TLP).We theoretically proved the advan-tages of RMAC over TLP and evaluated RMAC over *** simulation results show that RMAC spends half the latency of TLP,as well as consumes less energy than TLP.

关键词： WSN MAC routing energy efficient latency-reducing

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高温超导斜螺线管缆线磁体样机设计与开发

低温与超导 2023年第9期51卷 1-6,37页

作者：樊鲁阳宋彭肖冕钧邵良俊冯峰瞿体明清华大学机械工程系北京100084 清华大学深圳国际研究生院深圳518055

为研究Gantry磁体的关键技术,设计了一台由螺旋型超导集束缆线绕制的小型斜螺线管二极磁体样机。根据电磁设计,该样机的孔径82 mm,额定工作电流为3.25 kA,预计在4.2 K下达到0.50 T的中心二极场。在均匀电流假设下,Φ54 mm孔径内的磁场... 详细信息

为研究Gantry磁体的关键技术,设计了一台由螺旋型超导集束缆线绕制的小型斜螺线管二极磁体样机。根据电磁设计,该样机的孔径82 mm,额定工作电流为3.25 kA,预计在4.2 K下达到0.50 T的中心二极场。在均匀电流假设下,Φ54 mm孔径内的磁场均匀度可达到1.47×10^(-3)。未来将完成超导缆线绕制,在77 K和4.2 K下进行电流和场均匀性测试。

关键词：斜螺线管二极磁体 REBCO 复合缆线磁场均匀性

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跑道形高温超导转子磁体设计与测试

低温与超导 2019年第10期47卷 1-5页

作者：郝常宏瞿体明杨烨张涵白亮史正军宋萌摩擦学国家重点实验室清华大学机械工程系北京100084 东方电气中央研究院成都611731 广东电网有限责任公司电力科学研究院广州510080

基于前期开发的60 kW风力发电机样机,设计并制造了两个应用于直驱式风力发电机的转子磁体,包括磁体的电磁设计、结构设计及制备流程,磁体为两种形式的跑道形高温超导磁体。通过在77 K液氮温区的直流测试,获得了磁体的临界电流、电阻等参... 详细信息

基于前期开发的60 kW风力发电机样机,设计并制造了两个应用于直驱式风力发电机的转子磁体,包括磁体的电磁设计、结构设计及制备流程,磁体为两种形式的跑道形高温超导磁体。通过在77 K液氮温区的直流测试,获得了磁体的临界电流、电阻等参数,及电流-电压变化曲线;通过磁体在30 K氦气低温传导冷却系统中直流励磁测试,获得了系统降温曲线、磁场随电流的变化曲线。测试结果表明,磁体满足励磁和传导冷却要求,验证了磁体设计的合理性和运行的可靠性。

关键词：高温超导风力发电直驱式传导冷却

Effect of salinomycin on metastasis and invasion of bladder cancer cell line T24

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Asian Pacific Journal of Tropical Medicine 2015年第7期8卷 575-578页

作者： Hu qu Bo Ma Hao-Feng Yuan Zhong-Yang Wang Sheng-Jie Guo Jing Zhang Sixth Hospital Affiliated to Zhongshan University Shilong People's Hospital of Dongguan City Tumor Hospital Affiliated to Zhongshan University

Objective: To explore the effect of salinomycin on the metastasis and invasion of bladder cancer cell line T24 by regulating the related protein expression in the process of epithelialmesenchymal transition(EMT), and to provide experimental basis for the treatment of urological tumors. Methods: The bladder cancer cell line T24 was cultured in vitro. The rat bladder tumor model was established in vivo. The rats were randomized into two groups, among which the rats in the experiment group were given intraperitoneal injection of salinomycin, while the rats in the control group were given intraperitoneal injection of normal saline. The change of tumor cells in the two groups was observed. Transwell was used to detect the cell migration and invasion abilities, Real-time PCR was used to detect the expression of m RNA, while Western-blot was utilized for the determination of the expressions of E-cadherin and vimentin proteins. Results: The metastasis and invasion abilities of serum bladder cancer cell line T24 after salinomycin treatment in the experiment group were significantly reduced when compared with those in the control group, and the tumor metastasis lesions were decreased from an average of 1.59 to 0.6(Ptiming point in the experiment group was significantly lower than that in the control group(P<0.05). The serum m RNA level and E-cadherin expression in the tumor tissues in the experiment group were significantly higher than those in the control group, while vimentin expression level was significantly lower than that in the control group(P<0.05). Conclusions: Salinomycin can suppress the metastasis and invasion of bladder cancer cells, of which the mechanism is probably associated with

关键词： Salinomycin Bladder cancer Metastasis and invasion Epithelial-mesenchymal transition

Origins,timing and introgression of domestic geese revealed by whole genome data

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Journal of Animal Science and Biotechnology 2023年第3期14卷 936-949页

作者： Junhui Wen Haiying Li Huie Wang Jincheng Yu Tao Zhu Jinxin Zhang Xinghua Li Zhihua Jiang Zhonghua Ning Lujiang qu Department of Animal Genetics and Breeding National Engineering Laboratory for Animal BreedingCollege of Animal Science and TechnologyChina Agricultural UniversityBeijingChina College of Animal Science Xinjiang Agricultural UniversityUrumqiChina Xinjiang Production&Construction Corps Key Laboratory of Protection and Utilization of Biological Resources in Tarim Basin AlarXinjiangChina College of Animal Science Tarim UniversityAlarXinjiangChina Liaoning Academy of Agricultural Sciences ShenyangChina Department of Animal Sciences Washington State UniversityPulmanUSA

Background Geese are among the most important poultry species in the *** current generally accepted hypothesis is that the European domestic geese originated from greylag geese(Anser anser),and Chinese domestic geese have two origins,most of which originated from swan geese(Anser cygnoides),and the Yili goose originated from greylag *** explain the origin and demographic history of geese,we selected 14 goose breeds from Europe and China and wild populations of swan and greylag geese,and whole genome sequencing data were obtained for 74 *** Population structure analysis and phylogenetic trees showed that the wild ancestor of Chinese domestic geese,except for Yili,is the swan geese,and the wild ancestor of Chinese Yili and European domestic geese is greylag *** of the demographic history suggests that the domestication of Chinese geese occurred~3499 years ago and that of the European geese occurred~7552 years ***,gene flow was observed between domestic geese and their wild *** of introgression showed that Yili geese had been introgressed by Chinese domestic geese,and the body size of Yili geese may be influenced by introgression events of some growthrelated genes,including *** Our study provides evidence for the origin of geese at the genome-wide level and advances the understanding of the history of goose domestication and the traits affected by introgression events.

关键词： Domestication Goose Introgression Phylogeny

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桂林“5.22”极端强降雨过程的观测分析

暴雨灾害 2024年第3期43卷 313-321页

作者：翟丽萍梁依玲周云霞屈梅芳黄晴黄荣广西壮族自治区气象台南宁530022

2023年5月22日凌晨至上午,桂林市区北部发生极端强降雨,1 h和3 h雨量均突破当地历史记录,导致严重城市内涝。利用常规观测、地面加密自动站、多普勒天气雷达以及ERA5再分析等资料对此次强降雨过程进行分析。结果表明:(1)过程发生在副热... 详细信息

2023年5月22日凌晨至上午,桂林市区北部发生极端强降雨,1 h和3 h雨量均突破当地历史记录,导致严重城市内涝。利用常规观测、地面加密自动站、多普勒天气雷达以及ERA5再分析等资料对此次强降雨过程进行分析。结果表明:(1)过程发生在副热带高压边缘,受低层切变线和地面冷锋南下影响,持续增强的西南急流为极端强降雨提供充足的水汽和能量;(2)强降雨回波由线状对流演变,线状对流与地面冷空气适时相遇,移向和形态发生改变,同时其西侧不断发展的新生单体加入形成“列车效应”,导致极端降雨产生,且降雨回波呈现低质心高效率的特征;(3)弱冷空气适时入侵,增强对流降雨并加强冷池出流,在其前沿的暖湿区域中触发新生对流,有利于强降雨的发展和持续;(4)对流单体在东移过程中通过云桥合并和云体扩大发展两种方式合并形成新的云团,并迅速发展,使降雨增强,对流单体之间的相互作用和合并是强降雨持续和加强的主要机制;(5)国内多家业务模式均低估此次过程雨强,预报降雨中心存在偏差,主要原因是模式预报地面冷空气影响时间出现偏差。

关键词：极端强降雨冷空气单体合并可预报性

基于经肛多点全层穿刺活检构建局部进展期直肠癌新辅助治疗后病理完全缓解预测模型

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中华胃肠外科杂志 2024年第4期27卷 403-411页

作者：金莹翟志伟孙丽婷夏平佃胡航江从庆赵宝成渠浩钱群戴勇姚宏伟王振军韩加刚首都医科大学附属北京朝阳医院普通外科北京100020 首都医科大学附属北京友谊医院普通外科北京100050 山东大学齐鲁医院普通外科济南250012 武汉大学中南医院普通外科武汉430071

目的探讨经肛多点全层穿刺活检(TMFP)病理结果在预测局部进展期直肠癌(LARC)患者新辅助放化疗(NCRT)后病理完全缓解(pCR)的价值,建立预测模型为LARC的治疗提供临床指导。方法本研究为多中心前瞻性队列研究,收集首都医科大学附属北京朝... 详细信息

目的探讨经肛多点全层穿刺活检(TMFP)病理结果在预测局部进展期直肠癌(LARC)患者新辅助放化疗(NCRT)后病理完全缓解(pCR)的价值,建立预测模型为LARC的治疗提供临床指导。方法本研究为多中心前瞻性队列研究,收集首都医科大学附属北京朝阳医院(50例)、首都医科大学附属北京友谊医院(41例)、山东大学齐鲁医院(16例)和武汉大学中南医院(3例)4家医院2020年4月至2023年3月间的110例LARC患者资料,患者均在完成标准NCRT治疗后接受TMFP。本研究的观察指标包括:(1)患者临床病理特征;(2)临床完全缓解(cCR)和TMFP对LARC患者NCRT后pCR的判断效力;(3)纳入不同医院、性别、年龄、临床T分期和N分期、肿瘤下缘距肛缘距离、基线血清癌胚抗原(CEA)和糖类抗原(CA)19-9水平、化疗方案、免疫抑制剂的使用与否、放疗剂量、放疗后等待手术时间、手术方式、放化疗后临床T分期和N分期、放化疗后CEA和CA19-9水平、临床完全缓解(cCR)、TMFP病理结果、穿刺方式(体内或体外)、穿刺针数、穿刺时间等因素,通过单因素分析及多因素logistic回归分析筛选出LARC患者NCRT后pCR的影响因素;(4)基于多因素分析结果构建预测模型,利用受试者工作特征(ROC)曲线、校准曲线及临床决策(DCA)曲线分析评估所建立模型的性能。pCR定义为直肠癌NCRT后手术切除标本(包括清扫淋巴结)中显微镜下肿瘤细胞完全消失,即ypT0+N0。cCR参照中国直肠癌新辅助治疗后等待观察数据库研究协作组(CWWD)标准,需满足内镜检查无溃疡和结节;直肠指诊阴性;直肠核磁T2及DWI序列无肿瘤信号、血清CEA水平正常以及盆腔CT/MRI未见复发征象等条件。结果110例患者中,45例(40.9%)达到pCR,NCRT治疗联合免疫检查点抑制剂34例(30.9%)。穿刺前评估为cCR病例为38例(34.5%),其中体内穿刺43例(39.1%),穿刺后无肠瘘、阴道损伤、前列腺损伤和骶前出血等并发症,仅1例(2.3%)少量便血,经肛门填塞压迫止血后症状缓解。cCR判断pCR的灵敏度为57.8%(26/45),特异度为81.5%(53/65),准确性为71.8%(79/110),阳性预测值为68.4%(26/38),阴性预测值73.6%(53/72)。而TMFP病理判断pCR的灵敏度为100.0%(45/45),特异度为66.2%(43/65),准确性为80.0%(88/110),阳性预测值为67.2%(45/67),阴性预测值为100.0%(43/43)。本研究TMFP对pCR的灵敏度(100.0%比57.8%,χ^(2)=24.09,P<0.001)高于cCR,差异有统计学意义;但两者对pCR的准确性比较,差异无统计学意义(80.0%比71.8%,χ^(2)=2.01,P=0.156)。单因素和多因素logistic回归分析结果显示:肿瘤下缘距肛缘距离≥4 cm(OR=7.84,95%CI:1.48~41.45,P=0.015)、非cCR(OR=4.81,95%CI:1.39~16.69,P=0.013)、TMFP病理结果(OR=114.29,95%CI:11.07~1180.28,P<0.001)是LARC患者NCRT后pCR预测的危险因素,而体内穿刺(OR=0.02,95%CI:0.05~0.77,P=0.020)是LARC患者NCRT后pCR预测的保护因素。基于前述4个因素所建立预测模型的ROC曲线下面积(AUC)为0.934(95%CI:0.892~0.977),提示模型具有较好区分度。校准曲线相对接近理想45°参考线,表明模型的预测值与实际值吻合良好。DCA曲线显示该模型具有较好的临床净获益。结论纳入TMFP病理结果的预测模型在预测局部进展期直肠癌NCRT后pCR方面有较好的准确率,可能为临床个体化精准治疗提供决策依据。

关键词：直肠肿瘤,局部进展期新辅助放化疗经肛多点全层穿刺活检病理完全缓解列线图预测模型

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一种抗干扰的电容式触摸传感控制器设计

电子与封装 2024年第3期24卷 92-96页

作者：冯海英王芬芬刘梦影屈佳龙兰亚峰中科芯集成电路有限公司江苏无锡214072

随着触控技术的广泛应用,用于按键应用的电容式触控呈快速发展趋势,其抗干扰性也愈发受到关注。设计了一种抗干扰的电容式触摸传感控制器,该电容式触摸传感控制器不仅可以任意配置充电及电荷转移时序,还具备扩频功能。仿真结果表明,该... 详细信息

随着触控技术的广泛应用,用于按键应用的电容式触控呈快速发展趋势,其抗干扰性也愈发受到关注。设计了一种抗干扰的电容式触摸传感控制器,该电容式触摸传感控制器不仅可以任意配置充电及电荷转移时序,还具备扩频功能。仿真结果表明,该电容式触摸传感控制器具有良好的灵活性和抗干扰性。

关键词：电容式扩频抗干扰灵活性