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De.onstration of the.te.t-re.e.t re.iability and se.sitivity of the.Lowe. Limb Functional Inde.-10 as a me.sure.of functional re.ove.y post burn injury:a cross-se.tional re.e.te. me.sure. study de.ign

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Burns & Trauma 2016年第2期4卷 153-159页

作者： Margare. e.Ryland tiffany L.Grisbrook Fiona M.Wood Michae. Phillips Dale.W.e.gar School of Physiothe.apy and e.e.cise.Scie.ce Curtin UniversityBentley 6102WAAustralia School of Physiothe.apy and e.e.cise.Scie.ce Curtin UniversityBentley 6102WAAustralia Fiona Wood Foundation of We.te.n Australia Fiona Stanley Hospital11 Warren DriveMurdoch 6150WAAustralia Fiona Wood Foundation of We.te.n Australia Fiona Stanley Hospital11 Warren DriveMurdoch 6150WAAustralia State.Adult Burn Unit Fiona Stanley HospitalLevel 411 Warren Smith DriveMurdoch 6150WAAustralia Burn Injury Re.e.rch Unit The University of Western AustraliaCrawley 6009WAAustralia Harry Pe.kins Institute.of Me.ical Re.e.rch The University of Western AustraliaCrawley 6009WAAustralia Fiona Wood Foundation of We.te.n Australia Fiona Stanley Hospital11 Warren DriveMurdoch 6150WAAustralia State.Adult Burn Unit Fiona Stanley HospitalLevel 411 Warren Smith DriveMurdoch 6150WAAustralia Burn Injury Re.e.rch Unit The University of Western AustraliaCrawley 6009WAAustralia Burn Injury Re.e.rch Node The University of Notre Dame Australia19 Mouat StFremantle 6160WAAustralia

Background:Lowe. limb burns can significantly de.ay re.ove.y of *** lowe. limb functional outcome. is challe.ging in the.unique.burn patie.t population and ne.e.sitate. the.use.of re.iable.and valid *** aims of this study we.e.to e.amine.the.te.t-re.e.t re.iability,se.sitivity,and inte.nal consiste.cy of Se.tions 1 and 3 of the.Lowe. Limb Functional Inde.-10(LLFI-10)que.tionnaire.for me.suring functional ability in patie.ts with lowe. limb burns ove. ***:Twe.ty-nine.adult patie.ts who had sustaine. a lowe. limb burn injury in the.pre.ious 12 months comple.e. the.te.t-re.e.t proce.ure.of the.*** addition,the.minimal de.e.table.change.MDC)was calculate. for Se.tion 1 and 3 of the.*** 1 is focuse. on the.activity limitations e.pe.ie.ce. by patie.ts with a lowe. limb disorde. whe.e.s Se.tion 3 involve. patie.ts indicating the.r curre.t pe.ce.tage.of pre.injury ***:Se.tion 1 of the.LLFI-10 de.onstrate. e.ce.le.t te.t-re.e.t re.iability(intra-class corre.ation coe.ficie.t(ICC)0.98,95%CI 0.96–0.99)whilst Se.tion 3 de.onstrate. high te.t-re.e.t re.iability(ICC 0.88,95%CI 0.79–0.94).MDC score. for Se.tions 1 and 3 we.e.1.27 points and 30.22%,*** consiste.cy was de.onstrate. with a significant ne.ative.association(rs=?0.83)be.we.n Se.tions 1 and 3 of the.LLFI-10(pe.onstrate. that Se.tion 1 and 3 of the.LLFI-10 are.re.iable.for me.suring functional ability in patie.ts who have.sustaine. lowe. limb burns in the.pre.ious 12 months,and furthe.more.Se.tion 1 is se.sitive.to change. in patie.t function ove. time.

关键词： Outcome.me.sure Que.tionnaire Lowe. limb function Inte.nal consiste.cy Minimal de.e.table.change Burn

Ide.tification of Ca2+ signaling compone.ts in ne.ral ste./proge.itor ce.ls during diffe.e.tiation into ne.rons and glia in intact and dissociate. ze.rafish ne.rosphe.e.

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Scie.ce.China(Life.Scie.ce.) 2018年第11期61卷 1352-1368页

作者： Man Kit Tse.Ting Shing Hung Ching Man Chan tiffany Wong Mike.Dorothe. Cathe.ine.Le.le.c Marc More.u Andre. L.Mille. Sarah e.We.b Division of Life.Scie.ce.& State.Ke. Laboratory of Mole.ular Ne.roscie.ce HKUSTClear Water BayHongKongChina Ce.tre.de.Biologie.du De.e.oppe.e.t(CBD) Centre de Biologie Integrative(CBI)Universite de ToulouseCNRSUPSToulouse F-31062France

The.de.e.opme.t of the.CNS in ve.te.rate.e.bryos involve. the.ge.e.ation of diffe.e.t sub-type. of ne.rons and glia in a comple. but highly-orde.e. spatio-te.poral manne.. Ze.rafish are.commonly use. for e.ploring the.de.e.opme.t, plasticity and re.e.e.ation of the.CNS, and the.re.e.t de.e.opme.t of re.iable.protocols for isolating and culturing ne.ral ste./proge.itor ce.ls(NSCs/NPCs) from the.brain of adult fish now e.able. the.e.ploration of me.hanisms unde.lying the.induction/spe.ification/diffe.e.tiation of the.e.ce.ls. He.e. we.re.ine. a protocol to ge.e.ate.prolife.ating and diffe.e.tiating ne.rosphe.e. from the.e.tire.brain of adult ze.rafish. We.de.onstrate. via RT-qPCR that some.isoforms of ip3 r, ryr and stim are.upre.ulate./downre.ulate. significantly in diffe.e.tiating ne.rosphe.e., and via immunolabe.ling that 1,4,5-inositol trisphosphate.re.e.tor(IP3 R) type.1 and ryanodine.re.e.tor(RyR) type.2 are.diffe.e.tially e.pre.se. in ce.ls with ne.ron-or radial glial-like.prope.tie.. Furthe.more. ATP but not caffe.ne.IP3 R and RyR agonists, re.pe.tive.y), induce. the.ge.e.ation of Ca^(2+) transie.ts in ce.ls e.hibiting ne.ron-or glial-like.morphology. The.e.re.ults indicate.the.diffe.e.tial e.pre.sion of compone.ts of the.Ca^(2+) -signaling toolkit in prolife.ating and diffe.e.tiating ce.ls. Thus, give. the.comple.ity of the.intact ve.te.rate.brain, ne.rosphe.e. might be.a use.ul syste. for e.ploring ne.rode.e.e.ative.dise.se.diagnosis protocols and drug de.e.opme.t using Ca^(2+) signaling as a re.d-out.

关键词： Ca^2+ signaling ne.rosphe.e. ze.rafish ne.ral ste./proge.itor ce.ls diffe.e.tiation IP3re.e.tors ryanodine re.e.tors STIM and Orai

Re.onstructing landscape. of ungulate.parturition and pre.ation using ve.e.ation phe.ology

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Curre.t Zoology 2022年第3期68卷 275-283页

作者： Paige.VAN De.VUURST Se.h A.MOORe.e.mund J.ISAAC Yve.te.CHe.AUX-IBRAHIM tiffany M.WOLF Luis e.e.COBAR De.artme.t of Fish and Wildlife.Conse.vation Virginia TechBlacksburgVA 24061USA De.artme.t of Biology and e.vironme.t Grand Portage Band of Lake Superior ChippewaGrand PortageMN 55605USA Ve.e.inary Population Me.icine University of MinnesotaSt PaulMN 55108USA

e.hance. ve.e.ation inde.(e.I)data can be.use. to ide.tify and de.ine.the.space.in which ungulate. practice.parturition and e.counte. *** study e.plore. the.use.of e.I data to ide.tify landscape. linke. to ungulate.parturition and pre.ation e.e.ts across space.time.and e.vironme.tal *** a case.study,we.use. the.moose.population(Alce. alce.)of northe.n Minne.ota in the.*** re.ote.y se.se. e.I data raste.s and global positioning syste. collar data,we.quantifie. how ve.e.ation phe.ology and moose.move.e.t shape. the.births and pre.ation of 52 moose.calve. from 2013 to 2020 on or adjace.t to the.Grand Portage.Indian *** known source. of pre.ation we.e.Ame.ican black be.rs(Ursus ame.icanus,n=22)and gray wolve.(Canis lupus,n=28).Sate.lite.de.ive. data summarizing se.sonal landscape.fe.ture. at the.local le.e. re.e.le. that landscape.he.e.oge.e.ty use.by moose.can he.p to quantitative.y ide.tify landscape. of parturition and pre.ation in space.and time.across large.*** phe.ology prove. to be.diffe.e.tiable.be.we.n adult moose.range.,site. of cow parturition,and site. of calf *** characte.istics of e.ch moose.group we.e.consiste.t and tractable.base. on e.vironme.t,sugge.ting that site. of parturition and pre.ation of moose.are.pre.ictable.in space.and *** is possible.that moose.se.e.te. spe.ific landscape. for parturition de.pite.risk of incre.se. pre.ation of the.r calve.,which could be.an e.ample.of an"e.ological trap."This analytical frame.ork can be.e.ploye. to ide.tify are.s for future.ungulate.re.e.rch on the.impacts of landscape.on parturition and pre.ation dynamics.

关键词： be.r e.I moose parturition pre.ation pre. ve.e.ation phe.ology

e.cigare.te. and arte.ial he.lth:A re.ie. of the.link be.we.n vaping and athe.oscle.osis progre.sion

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World Journal of Cardiology 2024年第12期16卷 707-719页

作者： Muhammad Hassan Julia Vinagolu-Baur Vivian Li Ke.ly Frasie. Grace.He.rick tiffany Scotto e.ica Rankin De.artme.t of Me.icine Nuvance HealthVassar Brothers Medical CenterPoughkeepsieNY 12601United States De.artme.t of Me.ical e.ucation State University of New YorkUpstate Medical UniversitySyracuseNY 13210United States De.artme.t of Me.ical e.ucation Alabama College of Osteopathic MedicineDothanAL 36303United States De.artme.t of Me.icine University of Florida HealthJacksonvilleFL 32209United States De.artme.t of Me.ical e.ucation Nova Southeastern University Kiran C.Patel College of Osteopathic MedicineFort LauderdaleFL 33328United States

Re.e.t studie. have.sugge.te. an e.olving unde.standing of the.association be.twe.n vaping,spe.ifically e.e.tronic cigare.te.e.cigare.te.use.and the.progre.ssion of athe.oscle.osis,a significant contributor to cardiovascular ***-pite.the.pre.ailing pe.ce.tion of vaping as a safe. alte.native.to traditional toba-cco smoking,accumulating e.ide.ce.sugge.ts that the.ae.osols e.itte. by e.cigare.te. contain harmful constitue.ts that may promote.e.dothe.ial dysfunction,oxidative.stre.s,inflammation,and dyslipide.ia—ke. me.hanisms implicate. in athe.oscle.osis *** past re.e.rch,including e.pe.ime.tal studie. and clinical inve.tigations,has she. light on the.pote.tial cardiovascular risks associate. with vaping,gaps in knowle.ge.*** re.e.rch e.de.vors should focus on inte.pre.ing the.long-te.m e.fe.ts of vaping on athe.oscle.osis de.e.opme.t and progre.sion,e.ploring the.impact of diffe.e.t e.cigare.te.formu-lations and use. de.ographics,and ide.tifying e.fe.tive.strate.ie. for mitigating the.cardiovascular conse.ue.ce. of *** ide.tifying and addre.sing the.e.re.e.rch gaps,we.can e.hance.our unde.standing of the.cardiovascular implica-tions of vaping and inform e.ide.ce.base. inte.ve.tions and policie. to safe.guard public *** Tip:e.cigare.te.use.has be.n linke. to various cardiovascular risks,including the.progre.sion of *** the.pe.ce.tion of vaping as a safe. alte.native.to smoking,e.ide.ce.sugge.ts that e.cigare.te.ae.osols contain harmful substance. that contribute.to e.dothe.ial dysfunction,oxidative.stre.s,inflammation,and *** me.hanisms are.crucial in the.de.e.opme.t and progre.sion of *** re.ie. e.plore. multiple.face.s of e.cigare.te. and arte.ial he.lth,focusing on the.conne.tion be.we.n vaping and athe.oscle.osis *** pre.e.ts up-to-date.e.ide.ce.on pathophysiology and significant clinical implications,the.impact of various constitue.ts,and discusse. cont

关键词： e.cigare.te. Vaping Athe.oscle.osis Cardiovascular dise.se Dyslipide.ia Oxidative.stre.s Nicotine

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亚热带竹林挥发性有机物排放的模拟

生态环境学报 2015年第12期24卷 1923-1937页

作者：白建辉 DUHL tiffany 余树全王彬郝楠中国科学院大气物理研究所中层大气与全球环境探测重点实验室北京100029 美国美国国家大气研究中心美国Boulder CO 80307 浙江农林大学浙江杭州311300 德国宇航中心德国韦斯灵82234

2012年7月至2013年1月,采用松弛涡度积累(Re.axe. e.dy Accumulation)技术在我国浙江省亚热带竹林测量了挥发性有机物(BVOC)冠层尺度的排放通量,同步测量了气象参数、太阳辐射(总辐射、直接辐射、光合有效辐射PAR)。利用PAR能量平衡原理... 详细信息

2012年7月至2013年1月,采用松弛涡度积累(Re.axe. e.dy Accumulation)技术在我国浙江省亚热带竹林测量了挥发性有机物(BVOC)冠层尺度的排放通量,同步测量了气象参数、太阳辐射(总辐射、直接辐射、光合有效辐射PAR)。利用PAR能量平衡原理,建立了冠层尺度异戊二烯和单萜烯排放的经验模式,经验模式对于日变化、季节变化有较好的模拟。采用不同方法对经验模式进行检验,一般而言,BVOC的模拟值高于测量值。经验模式与Me.ANv2.1全球生物排放模式对BVOC排放有比较一致的模拟结果,标准状况下(温度t=30℃、PAR=1 500μmol·m^(-2)·s^(-1)排放因子较接近(异戊二烯分别为4.00和3.60 mg·m^(-2)·h^(-1),单萜烯分别为0.12和0.16 mg·m^(-2)·h^(-1))。经验模式的计算结果表明:竹林BVOC排放主要集中于夏季(7-9月)且以异戊二烯为主(占BVOC排放的87.3%~95.8%)。利用经验模式计算了BVOC排放对各个因子(PAR、水汽、S/Q-散射因子,散射辐射/总辐射)变化的敏感性:当各个因子增加率大于40%时,异戊二烯对PAR的变化最敏感,其次是水汽因子,再次是S/Q;单萜烯对S/Q的变化最敏感,其次是水汽因子,再次是PAR;单萜烯比异戊二烯对S/Q的变化更敏感;异戊二烯和单萜烯对各因子变化的响应是非线性的。冠层尺度上BVOC的排放量与卫星测量的HCHO柱浓度(mole.·cm^(-1))之间有良好的线性关系:异戊二烯排放量(mg·m^(-2)·h^(-1))=3.93×10^(-16)HCHO-2.81,单萜烯排放量(mg·m^(-2)·h^(-1))=1.24×10^(-17)HCHO-0.05。对比我国不同生态系统实测的排放通量、排放因子,异戊二烯排放以亚热带竹林最高,其次为温带森林,草地最低;单萜烯排放以温带森林最高,亚热带竹林次之,草地最低。

关键词：挥发性有机物排放通量光合有效辐射经验模式排放因子

COVID-19 vaccination produce. e.e.cise.re.ponsive.SARS-CoV-2 spe.ific T-ce.ls re.ardle.s of infe.tion history

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Journal of Sport and He.lth Scie.ce 2024年第1期13卷 99-107页

作者： Kyle.A.Smith tiffany M.Zúñiga Forre.t L.Bake. He.e.a Batatinha Charle. R.Pe.lar Shane.C.Burge.s Michae. P.Gustafson e.manue. Katsanis Richard J.Simpson School of Nutritional Scie.ce. and We.lne.s The University of ArizonaTucsonAZ 85721USA De.artme.t of Pe.iatrics The University of ArizonaTucsonAZ 85724USA Faculty of Sport Allied Health and Performance ScienceSt.Mary's UniversityTwickenham TW14SXUK Institute.of Sport e.e.cise.and He.lth University College LondonLondon WC1E 7HUUK De.artme.t of Animal and Comparative.Biome.ical Scie.ce. The University of ArizonaTucsonAZ 85721USA The.Unive.sity of Arizona Cance. Ce.te. The University of ArizonaTucsonAZ 85719USA Laboratory Me.icine.and Pathology Mayo Clinic ArizonaPhoenixAZ 85054USA De.artme.t of Immunobiology The University of ArizonaTucsonAZ 85724USA De.artme.t of Me.icine The University of ArizonaTucsonAZ 85724USA De.artme.t of Pathology The University of ArizonaTucsonAZ 85724USA

Background:The.mobilization and re.istribution of se.e.e.acute.re.piratory syndrome.coronavirus 2(SARS-CoV-2)spe.ific T-ce.ls and ne.tralizing antibodie.(nAbs)during e.e.cise.is purporte. to incre.se.immune.surve.llance.and prote.t against se.e.e.coronavirus dise.se.2019(COVID-19).We.sought to de.e.mine.if COVID-19 vaccination would e.icit e.e.cise.re.ponsive.SARS-CoV-2 T-ce.ls and transie.tly alte. nAb ***:e.ghte.n he.lthy participants comple.e. a 20-min bout of grade. cycling e.e.cise.be.ore.and/or afte. re.e.ving a COVID-19 *** major le.kocyte.subtype. we.e.e.ume.ate. be.ore.during,and afte. e.e.cise.by flow cytome.ry,and immune.re.ponse. to SARS-CoV-2 we.e.de.e.mine. using whole.blood pe.tide.stimulation assays,T-ce.l re.e.tor(TCR)-βse.ue.cing,and SARS-CoV-2 nAb ***:COVID-19 vaccination had no e.fe.t on the.mobilization or e.re.s of major le.kocyte.subse.s in re.ponse.to inte.sity-controlle. grade. ***,non-infe.te. participants had a significantly re.uce. mobilization of CD4+and CD8+naive.T-ce.ls,as we.l as CD4+ce.tral me.ory T-ce.ls,afte. vaccination(synthe.ic immunity group);this was not se.n afte. vaccination in those.with prior SARS-CoV-2 infe.tion(hybrid immunity group).Acute.e.e.cise.afte. vaccination robustly mobilize. SARS-CoV-2 spe.ific T-ce.ls to blood in an inte.sity-de.e.de.t *** groups mobilize. T-ce.ls that re.cte. to spike.prote.n;howe.e.,only the.hybrid immunity group mobilize. T-ce.ls that re.cte. to me.brane.and nucle.capsid *** incre.se. significantly during e.e.cise.only in the.hybrid immunity ***:The.e.data indicate.that acute.e.e.cise.mobilize. SARS-CoV-2 spe.ific T-ce.ls that re.ognize.spike.prote.n and incre.se. the.re.istribution of nAbs in individuals with hybrid immunity.

关键词： Anti-viral COVID-19 e.e.cise.immunology SARS-CoV-2 T-Ce.ls Vaccine

Anti-inflammatory me.hanisms of the.nove. cytokine.inte.le.kin-38 in alle.gic asthma

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Ce.lular & Mole.ular Immunology 2020年第6期17卷 631-646页

作者： Xiaoyu Sun Tianhe.g Hou e.win Che.ng tiffany Nga-Te.g Iu Victor Wai-Hou Tam Ida Miu-Ting Chu Miranda Sin-Man Tsang Paul Kay-She.ng Chan Christophe. Wai-Ke. Lam Chun-Kwok Wong De.artme.t of Che.ical Pathology The Chinese University of Hong KongHong KongChina Cance. Ce.tre.Ce.tre.of Pre.ision Me.icine.Re.e.rch and Training Faculty of Health SciencesUniversity of MacaoMacaoChina Institute.of Chine.e.Me.icine.and State.Ke. Laboratory of Re.e.rch on Bioactivitie. and Clinical Applications of Me.icinal Plants The Chinese University of Hong KongHong KongChina De.artme.t of Microbiology The Chinese University of Hong KongHong KongChina Faculty of Me.icine.and State.Ke. Laboratory of Quality Re.e.rch in Chine.e.Me.icine. Macao University of Science and TechnologyMacaoChina Li Dak Sum Yip Yio Chin R&D Ce.tre.for Chine.e.Me.icine The Chinese University of Hong KongHong KongChina

We.e.ucidate. the.anti-inflammatory me.hanisms of IL-38 in alle.gic *** bronchial e.ithe.ial ce.ls and e.sinophils we.e.coculture. upon stimulation with the.viral RLR ligand poly(I:C)/LyoVe. or infe.tion-re.ate. cytokine.TNF-αto induce.e.pre.sion of cytokine./che.okine./adhe.ion *** dust mite.HDM)-induce. alle.gic asthma and humanize. alle.gic asthma NOD/SCID murine.mode.s we.e.e.tablishe. to asse.s anti-inflammatory me.hanisms in ***-38 significantly inhibite. induce. proinflammatory IL-6,IL-1β,CCL5,and CXCL10 production,and antiviral inte.fe.on-βand inte.ce.lular adhe.ion mole.ule.1 e.pre.sion in the.coculture.*** cytome.ry and RNA-se.ue.cing analysis re.e.le. that IL-38 could antagonize.the.activation of the.intrace.lular STAT1,STAT3,p38 MAPK,e.K1/2,and NF-κB pathways,and upre.ulate.the.e.pre.sion of the.host de.e.se.re.ate. ge.e.POU2AF1 and anti-alle.gic re.ponse.ge.e.*** inje.tion of IL-38 into HDM-induce. alle.gic asthma mice.could ame.iorate.airway hype.re.ctivity by de.re.sing the.accumulation of e.sinophils in the.lungs and inhibiting the.e.pre.sion of the.Th2-re.ate. cytokine. IL-4,IL-5,and IL-13 in the.bronchoalve.lar lavage.fluid(BALF)and lung *** e.amination indicate. lung inflammation was alle.iate. by re.uctions in ce.l infiltration and goble. ce.l hype.plasia,toge.he. with re.uce. Th2,Th17,and innate.lymphoid type.2 ce.l numbe.s but incre.se. proportions of re.ulatory T ce.ls in the.lungs,sple.n,and lymph ***-38 administration suppre.se. airway hype.re.ctivity and asthma-re.ate. IL-4 and IL-5 e.pre.sion in humanize. mice.toge.he. with significantly de.re.se. CCR3^(+) e.sinophil numbe.s in the.BALF and lungs,and a re.uce. pe.ce.tage.of human CD4^(+)CRTH2^(+)Th2 ce.ls in the.lungs and me.iastinal lymph ***,our re.ults de.onstrate. the.anti-inflammatory me.hanisms of IL-38 and provide. a basis for the.de.e.opme.t of a re.ulatory cytokine.base. tre.tme.t for alle.gic

关键词： alle.gic asthma e.sinophils IL-38 ILC2s Tre.s

An introduction to dre.se.-atom adiabatic pote.tials for ultracold atoms

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Instrume.tation 2015年第4期2卷 76-84页

作者： tiffany Harte.e.liot Be.tine.e.ward Owe. XU Dongyang Be.jamin Yue. Christophe. Foot Clare.don Laboratory University of Oxford

We.give.a simple.introduction to the.the.re.ical tre.tme.t of atoms inte.acting strongly w ith e.e.tromagne.ic fie.ds in the.radiofre.ue.cy,microw ave.and lase. domains. In particular,w e.discuss the.conce.t of dre.se. atoms,w hich conside.s the.combination of the.atom and photons as a composite.physical syste.. This pow e.ful conce.t has a w ide.range.of applications in atomic physics and w e.give.a fe. e.ample. of its use.in the.manipulation of ultracold atoms in adiabatic pote.tials. The.e.e.ample. are.se.e.te. from e.pe.ime.tal w ork conducte. by our re.e.rch te.m in Oxford but the.e.are.nume.ous othe. applications and w e.outline.some.future.possibilitie..

关键词： Ultracold atoms dre.se. pote.tials

Surgical manage.e.t of facial dog bite.trauma:A conte.porary pe.spe.tive.and re.ie.

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World Journal of Otorhinolaryngology-He.d and Ne.k Surge.y 2023年第2期9卷 123-130页

作者： tiffany Che. Maria Karim Zachary T.Grace.Andre. R.Magdich e.ic C.Carniol Brian e.Be.son Pe.e. F.Svide. Hacke.sack Me.idian School of Me.icine NutleyNew JerseyUSA Carniol Plastic Surge.y SummitNew JerseyUSA Hacke.sack Me.idian He.lth Hackensack University Medical CenterHackensackNew JerseyUSA Be.ge. Me.ical Associate. EmersonNew JerseyUsA

Obje.tive.To pe.form a re.ie. e.aluating manage.e.t of and complications ste.ming from dog bite.trauma sustaine. to the.he.d and ne.k ove. the.past *** Source.:PubMe. and Cochrane.***:The.authors se.rche. the.PubMe. and Cochrane.Library database. for re.e.ant publishe. lite.ature.A total of 12 pe.r-re.ie.e. canine.e.clusive.se.ie. inclusive.of 1384 patie.t case. de.cribing facial dog bite.trauma me. inclusion *** including fracture.,lace.ations,contusions,and othe. soft-tissue.injurie. we.e.*** re.ate. to clinical course.and manage.e.t,ope.ating room re.uire.e.ts,and antibiotic usage.we.e.compile. and *** trauma and surgical manage.e.t complications we.e.also ***:75.5%of patie.ts sustaining dog bite. re.uire. surgical *** the.e.patie.ts,7.8%suffe.e. from postsurgical complications,including hype.trophic scarring(4.3%),postope.ative.infe.tion(0.8%),or ne.ve.de.icits and pe.siste.t pare.the.ias(0.8%).Prophylactic antibiotics we.e.administe.e. to 44.3%of patie.ts tre.te. for facial dog bite. and the.ove.all infe.tion rate.was 5.6%.Concomitant fracture.was pre.e.t in 1.0%of ***:Primary closure.ofte. in the.OR may be.ne.e.sary,with fe. case. re.uiring grafts or *** should be.aware.that the.most common complication is hype.trophic *** re.e.rch is ne.de. to e.ucidate.the.role.of prophylactic antibiotics.

关键词： bite canine dog face facial injury lace.ation trauma