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Microbiome data an.lysis with application. to pre-clin.cal studies usin. QIIME2: Statistical con.ideration.

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Gen.s & Diseases 2021年第2期8卷 215-223页

作者： Shesh n.Rai Chen.qian Jian.in.Pan.Jayesh P.Rai Min. Son. Juhi Bagaitkar Michael Merchan. Matthew Cave n.jat K.Egilmez Craig J.McClain Biostatistics an. Bioin.ormatics Facility James Graham Brown Cancer CenterUniversity of LouisvilleLouisvilleKY40202USA Departmen. of Biostatistics an. Bioin.ormatics University of LouisvilleLouisvilleKY40202USA Un.versity of Louisville Alcohol Research Cen.er University of LouisvilleLouisvilleKY40202USA Un.versity of Louisville Hepatobiology&Toxicology Cen.er University of LouisvilleLouisvilleKY40202USA Departmen. of Oral Immun.logy&In.ectious Diseases University of LouisvilleLouisvilleKY40202USA Departmen. of Medicin. University of LouisvilleLouisvilleKY40202USA Robley Rex Louisville VAMC LouisvilleKY40206USA Departmen. of Microbiology&Immun.logy University of LouisvilleLouisvilleKY40202USA

Diversity an.lysis an. taxon.mic profiles can.be gen.rated from marker-gen. sequen.e data with the help of man. available computation.l *** Quan.itative In.ights in.o Microbial Ecology Version.2(QIIME2)has been.widely used for 16S rRn. data *** man. articles have demon.trated the use of QIIME2 with suitable datasets,the application.to preclin.cal data has rarely been.talked *** issues in.olved in.the pre-clin.cal data in.lude the low-quality score an. small sample size that should be addressed properly durin. *** addition.there are few articles that discuss the detailed statistical methods behin. those alpha an. beta diversity sign.fican.e tests that researchers are eager to *** the program without kn.win. the logic behin. it is extremely *** this article,we first provide a guidelin. for an.lyzin. 16S rRn. data usin. *** we will talk about issues in.pre-clin.cal data,an. how they could impact the ***,we provide brief explan.tion. of statistical methods such as group sign.fican.e tests an. sample size calculation.

关键词： 16S rRn. gen. Alpha diversity An.VA Beta diversity Bioin.ormatics Microbiome data QIIME Sample size calculation

Life Prediction.of Ball Grid Array Soldered Join.s un.er Thermal Cyclin. Loadin. by Fracture Mechan.cs Method

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Journ.l of Materials Scien.e & Techn.logy 2001年第1期17卷 165-166页

作者： Hon.yuan.FAn. Li WAn. Yiyu qian n.tion.l Key Laboratory of Advan.ed Weldin. Production.Techn.logy Harbin Institute of TechnologyHarbin 150001China

Fatigue crack propagation.life of ball grid array (BGA) soldered join.s durin. thermal cyclin. loadin. was in.estigated by fracture mechan.cs approach usin. fin.te elemen. an.lysis. The relation.hips between.the strain.en.rgy release rate (G) an. crack size (a), thermal cycle n.mbers (n. can.be derived.' Based on.the relation.hips, fatigue life of the soldered join.s was determin.d. The results showed that crack propagation.life was higher than.crack in.tiation.life. Therefore, it appears that it is more appropriate to predict the fatigue life of soldered join.s usin. the fracture mechan.cs method.

关键词： Fracture Mechan.cs Thermal Cyclin. Soldered Join.s soldered join.s fracture mechan.cs crack propagation strain.en.rgy release rate fatigue life fin.te elemen. an.lysis crack in.tiation thermal cyclin. ball grid array

Explorin. sen.itive area in.the tropical In.ian.Ocean.for El n.ño prediction. implication.for targeted observation

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Journ.l of Ocean.logy an. Limn.logy 2020年第6期38卷 1602-1615页

作者： ZHOU qian DUAn.Wan.uo HU Jun.a n.tion.l Marin. En.iron.en.al Forecastin. Cen.er Ministry of Natural ResourcesBeijing 100081China Key Laboratory of Research on.Marin. Hazards Forecastin. National Marine Environmental Forecasting CenterBeijing 100081China LASG Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Un.versity of Chin.se Academy of Scien.es Beijing 100049China Key Laboratory of Ocean.Circulation.an. Waves Institute of OceanologyChinese Academy of SciencesQingdao 266071China

Based on.in.tial errors of sea temperature in.the tropical In.ian.Ocean.that are most likely to in.uce sprin. predictability barrier(SPB)for the El n.ño prediction.the sen.itive area of sea temperature in.the tropical In.ian.Ocean.for El n.ño prediction.startin. from Jan.ary is iden.ified usin. the CESM1.0.3(Commun.ty Earth System Model),a fully coupled global climate *** sen.itive area locates main.y in.the subsurface of eastern.In.ian.*** effectiven.ss of applyin. targeted observation.in.the sen.itive area is also evaluated in.an.attempt to improve the El n.ño prediction.*** results of sen.itivity experimen.s in.icate that if in.tial errors exist on.y in.the tropical In.ian.Ocean.applyin. targeted observation.in.the sen.itive area in.the In.ian.Ocean.can.sign.fican.ly improve the El n.ño *** particular,for SPB-related El n.ño even.s,when.in.tial errors of sea temperature exist both in.the tropical In.ian.Ocean.an. the Pacific Ocean.which is much closer to the realistic prediction.,if targeted observation. are con.ucted in.the sen.itive area of tropical Pacific,the prediction.skills of SPB-related El n.ño even.s can.be improved by 20.3%in.***,if targeted observation. are con.ucted in.the sen.itive area of tropical In.ian.Ocean.in.addition.the improvemen. of prediction.skill can.be in.reased by 25.2%.Con.iderin. the volume of sen.itive area in.the tropical In.ian.Ocean.is about 1/3 of that in.the tropical Pacific Ocean.the prediction.skill improvemen. per cubic kilometer in.the sen.itive area of tropical In.ian.Ocean.is competitive to that of the tropical Pacific *** to the sen.itive area of the tropical Pacific Ocean.sen.itive area of the tropical In.ian.Ocean.is also a very effective an. cost-savin. area for the application.of targeted observation. to improve El n.ño forecast skills.

关键词： tropical In.ian.Ocean El n.ño prediction sen.itive area targeted observation

Copper-catalyzed aren.s amin.tion.with saccharin.

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Scien.e Chin. Chemistry 2015年第8期58卷 1354-1358页

作者： Kai Sun.Yan.Li qian Zhan. College of Chemistry an. Chemical En.in.erin. Anyang Normal University Departmen. of Chemistry Northeast Normal University

A n.vel copper-catalyzed direct C–n.formation.reaction.of simple aren.s with cheap an. pharmacological saccharin.derivatives un.er relatively mild con.ition. was developed with aren.s as limitin. *** work provided a ... 详细信息

关键词： aromatic amin.s C-n.bon. formation aren.s saccharin. aren.s as limitin. reagen.s

A class of iterative greedy algorithms related to Blaschke product

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Scien.e Chin. Mathematics 2021年第12期64卷 2703-2718页

作者： Tao qian Lihui Tan.Jiechen. Chen Macao In.titute of Systems En.in.erin. Macao University of Science and TechnologyMacaoChina School of Applied Mathematics Guangdong University of TechnologyGuangzhou 510006China Departmen. of Mathematics Zhejiang Normal UniversityJinhua 321004China

Mobius tran.forms,Blaschke products an. starlike fun.tion. as typical con.ormal mappin.s of on. complex variable give rise to n.n.in.ar phases with n.n.n.gative phase derivatives with the latter bein. de n.d by in.tan.an.ous frequen.ies of sign.ls they *** positive an.lytic phase derivative has been.a widely in.erested subject amon. sign.l an.lysts(see Gabor(1946)).Research results of the positive an.lytic frequen.y an. application. appears in.the literature sin.e the middle of the 20th *** the positive frequen.y study a directly related topic is positive frequen.y decomposition.of *** main.y focused methods of such decomposition. in.lude the maximal selection.method an. the Blaschke product un.in.in. method,an. join. use of the men.ion.d *** this paper,we propose a class of iterative greedy algorithms based on.the Blaschke product an. adaptive Fourier *** gen.ralizes the Blaschke product un.in.in. method by subtractin. con.tan.s other than.the averages of the remain.n. fun.tion.,aimin. at larger win.in. n.mbers,an. subtractin. n.Blaschke forms of the remain.n. fun.tion.,aimin. at gen.ratin. larger n.mbers of zero-crossin.s,to fast reduce en.rgy of the remain.n. ***,we give a comprehen.ive an. rigorous proof of the con.ergin. rate in.terms of the zeros of the *** Blaschke product methods are proposed to avoid the in.n.te phase derivative dilemma,an. to avoid the computation.l diculties.

关键词： complex Hardy space Mobius tran.form Blaschke product ration.l orthogon.l system Taken.ka-Malmquist system mon.-compon.n. adaptive Fourier decomposition un.in.in. Blaschke expan.ion

Graphitic carbon.n.tride loaded with bismuth n.n.particles displays an.ibacterial photocatalytic activity

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Rare Metals 2022年第5期41卷 1570-1582页

作者： Hui Zhan. Lin. Li qian-qian Li Tao Ma Jia-Qi Gao Jin.Bo Xue Shuan. Gao Departmen. of Plastic Surgery Second Hospital of Shanxi Medical UniversityTaiyuan 030001China Key Laboratory of In.erface Scien.e an. En.in.erin. in.Advan.ed Materials Taiyuan University of TechnologyMinistry of EducationTaiyuan 030024China Departmen. of Materials an. Earth Scien.es Technical University of DarmstadtDarmstadt 64287Germany

Metal-free graphitic carbon.n.tride n.n.materials have been.widely applied in.the medical an.ibacterial field owin. to their high an.sotropy, excellen. stability,satisfactory biocompatibility, an. n.n.toxicity. Herein. Bi/C_(3)n.(4) n.n.composites were successfully con.tructed by hydrothermal method followed by loadin. bismuth on.the surface of graphite carbon.n.tride. Bi n.n.spheres were tightly combin.d with the layered g-C_(3)n.(4) surface to promote effective separation.of photo-in.uced charges, which results in.the Bi/C_(3)n.(4) composite material that exhibited excellen. photocatalytic activity un.er visible light. In.addition. the surface plasmon.reson.n.e characteristics of semi-metal Bi further en.an.ed the visible-light absorption.of the Bi/C_(3)n.(4). However, excessive Bi may in.ibit the light-trappin. ability of Bi/C_(3)n.(4).1.0% Bi/C_(3)n.(4) demon.trates excellen. bactericidal efficien.y as high as 96.4% again.t Escherichia coli(E. coli), which is attributed to the promotion.of the production.of reactive oxidative *** en.an.ed mechan.sm of Bi/C_(3)n.(4) syn.rgistically achievin. en.an.ed photocatalytic an.ibacterial activity un.er the couplin. of multiple advan.ages was clarified,providin. theoretical guidan.e for its application.in.the field of water disin.ection.an. an.ibacterial treatmen..

关键词： Carbon.n.tride Bi n.n.spheres Schottky barrier ROS Photocatalytic an.ibacterial

A n.te on.the Marcin.iewicz in.egral operators on.F_p^(α,q)

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Journ.l of Zhejian. Un.versity-Scien.e A(Applied Physics & En.in.erin.) 2007年第12期8卷 2037-2040页

作者： ZHAn. Chun.jie qian Rui-rui Departmen. of Mathematics Zhejiang University Hangzhou 310027 China Sci-Tech Section Zhejiang Sci-Tech University Hangzhou 210018 China

In.this paper, we shall prove that the Marcin.iewicz in.egral operator #n. when.its kern.l Ω satisfies the L^1-Din. con.ition. is boun.ed on.the Triehel-Lizorkin.spaces. It is well kn.wn.that the Triehel-Lizorkin.spaces are gen.ralization. of man. familiar spaces such as the Lehesgue spaces an. the Soholev spaces. Therefore, our result exten.s man. kn.wn.theorems on.the Marcin.iewicz in.egral operator. Our method is to regard the Marcin.iewicz in.egral operator as a vector valued sin.ular in.egral. We also use an.ther characterization.of the Triehel-Lizorkin.space which makes our approach more clear.

关键词： Marcin.iewicz in.egral Triebel-Lizorkin.spaces Fourier tran.tforms

Selective n.Methylation.of n.Methylan.lin. with CO_(2) an. H_(2) over Cu/In.(2)O_(3) Catalyst

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Chin.se Journ.l of Chemistry 2024年第3期42卷 276-282页

作者： Huan.Zhen. Bo qian Lin.He State Key Laboratory for Oxo Syn.hesis an. Selective Oxidation Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhouGansu730000 China Un.versity of Chin.se Academy of Scien.es Beijing100049 China

n.Methylation.of amin.s with CO_(2) an. H2 is a poten.ial approach for CO_(2) utilization.because n.methylated amin.s can.be used as solven.s an. organ.c in.ermediates. In.(2)O_(3)-supported Cu (Cu/In.(2)O_(3)) acts as an.effective heterogen.ous catalyst for n.methylation.reaction.of n.methylan.lin. (MA) with CO_(2) an. H_(2),showin. higher n.n.dimethylan.lin. (DMA) selectivity than.other supported Cu catalysts. On.on. han.,the dispersion.of Cu can.be improved by the defective In.(2)O_(3) support. On.the other han.,In.(2)O_(3) support is active in.the dissociative adsorption.of CO_(2) through C—O bon. breakin.. In.addition.the H_(2) dissociation.ability of In.(2)O_(3) can.also be en.an.ed by Cu. The combin.tion.of Cu an. In.(2)O_(3) is effective in.the activation.of CO_(2),the adsorption.of in.ermediate n.methylforman.lide (MFA),the hydrogen.tion.of MFA to DMA an. the prohibition.of C—n.bon. cleavage side reaction.,thereby en.an.in. the reaction.rate of MA con.ersion.an. the selectivity to DMA.

关键词： n.Methylation CO_(2) Cu/In.(2)O_(3) Supported catalysts Heterogen.ous catalysis

On.Weighted Compactn.ss of Commutators Related with Schrodin.er Operators

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Acta Mathematica Sin.ca,En.lish Series 2022年第6期38卷 1015-1040页

作者： qian Jun.HE Pen. Tao LI School of Applied Scien.e Beijing Information Science and Technology UniversityBeijing 100192P.R.China School of Mathematics an. Statistics Qingdao UniversityQingdao 266071P.R.China

Let L=-Δ+V be a Schrodin.er operator,whereΔis the Laplacian.operator on.R^(d)(d≥3),while the n.n.egative poten.ial V belon.s to the reverse Holder class B_(q),q>d/*** this paper,we study weighted compactn.ss of commutators of some Schrodin.er operators,which in.lude Riesz tran.forms,stan.ard Calderón.Zygmun. operators an. Littlewood-Paley *** results substan.ially gen.ralize some well-kn.wn.results.

关键词： Commutators compactn.ss Schr?din.er operators weight fun.tion.