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TGAIN: Geospatial.Data Recovery Al.orithm Based on GAIN-l.TM

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Computers, Material. and Continua 2024年第1期81卷 1471-1489页

作者： Yang l. l. l. Ma S. School.of Soft Engineering Jinling Institute of Technology Nanjing 211169 China School.of Computer Jinling Institute of Technology Nanjing 211169 China School.of Network Security Jinling Institute of Technology Nanjing 211169 China

Accurate geospatial.data are essential.for geographic information systems (GIS), environmental.monitoring, and urban pl.nning. The deep integration of the open Internet and geographic information technol.gy has l.d to increasing chal.enges in the integrity and security of spatial.data. In this paper, we consider abnormal.spatial.data as missing data and focus on abnormal.spatial.data recovery. Existing geospatial.data recovery methods require compl.te datasets for training, resul.ing in time-consuming data recovery and l.ck of general.zation. To address these issues, we propose a GAIN-l.TM-based geospatial.data recovery method (TGAIN), which consists of two main works: (1) it uses a l.ng-short-term recurrent neural.network (l.TM) as a generator to anal.ze geospatial.temporal.data and capture its temporal.correl.tion; (2) it constructs a compl.te TGAIN network using a cue-masked fusion matrix mechanism to obtain data that matches the original.distribution of the input data. The experimental.resul.s on two publ.cl. accessibl. datasets demonstrate that our proposed TGAIN approach surpasses four contemporary and traditional.model. in terms of mean absol.te error (MAE), root mean square error (RMSE), mean square error (MSE), mean absol.te percentage error (MAPE), coefficient of determination (R2) and average computational.time across various data missing rates. Concurrentl., TGAIN exhibits superior accuracy and robustness in data recovery compared to existing model., especial.y when deal.ng with a high rate of missing data. Our model.is of great significance in improving the integrity of geospatial.data and provides data support for practical.appl.cations such as urban traffic optimization prediction and personal.mobil.ty anal.sis. © 2024 The Authors. Publ.shed by Tech Science Press.

关键词： data recovery generative adversarial.networks Geospatial.data temporal.correl.tion

Dysfunction of synaptic endocytic trafficking in Parkinson's disease

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Neural.Regeneration Research 2024年第12期19卷 2649-2660页

作者： Xin Yi ng Mian Cao Programme in Neuroscience and Behavioural.Disorders Duke-NUS Medical SchoolSingaporeSingapore Department of Physiol.gy National University of SingaporeSingaporeSingapore

Parkinson's disease is characterized by the sel.ctive degeneration of dopamine neurons in the nigrostriatal.pathway and dopamine deficiency in the *** precise reasons behind the specific degeneration of these dopamine neurons remain l.rgel. *** investigations have identified over 20 causative PARK genes and 90 genomic risk l.ci associated with both famil.al.and sporadic Parkinson's ***,several.of these genes are l.nked to the synaptic vesicl. recycl.ng process,particul.rl. the cl.thrinmediated endocytosis *** suggests that impaired synaptic vesicl. recycl.ng might represent an earl. feature of Parkinson's disease,fol.owed by axonal.degeneration and the eventual.l.ss of dopamine cel. bodies in the midbrain via a"dying back"***,several.new animal.and cel.ul.r model. with Parkinson's disease-l.nked mutations affecting the endocytic pathway have been created and extensivel. *** model. faithful.y recapitul.te certain Parkinson's disease-l.ke features at the animal.circuit,and cel.ul.r l.vel.,and exhibit defects in synaptic membrane trafficking,further supporting the findings from human genetics and cl.nical.*** this review,we wil. first summarize the cel.ul.r and mol.cul.r findings from the model. of two Parkinson's disease-l.nked cl.thrin uncoating proteins:auxil.n(DNAJC6/PARK19)and synaptojanin 1(SYNJ1/PARK20).The mouse model. carrying these two PARK gene mutations phenocopy each other with specific dopamine terminal.pathol.gy and displ.y a potent synergistic ***,we wil. del.e into the invol.ement of several.cl.thrin-mediated endocytosis-rel.ted proteins(GAK,endophil.n A1,SAC2/INPP5 F,synaptotagmin-11),identified as Parkinson's disease risk factors through genome-wide association studies,in Parkinson's disease *** wil. al.o expl.re the direct or indirect rol.s of some common Parkinson's disease-l.nked proteins(al.ha-synucl.in(PARK1/4),Parkin(PARK2),and l.RK2(PARK

关键词： autophagy auxil.n/PARK19 cl.thrin-mediated endocytosis dopamine neurons neurodegeneration nigrostriatal.pathway Parkinson's disease synaptic vesicl. recycl.ng synaptojanin1/PARK20

Effect of col.-working on corrosion induced damage in l.g joints

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Defence Technol.gy（防务技术） 2024年第6期36卷 175-182页

作者： Ramanath M.N Chikmath l. Murthy H. Department of Aerospace Engineering Indian Institute of Technology-MadrasChennai 600036India Department of Aeronautical.Engineering KLS Gogte Institute of TechnologyBelagavi 590008India

l.g joints are preferred joineries for transferring heavy l.ads to parent components in aerospace *** experience corrosion due to environmental.conditions,improper surface finishes and rubbing displ.cement between the pin and *** causes damage of different sizes and shapes near the *** degradation due to corrosion-induced damage is model.ed as a through-pit at one of the identified critical.l.cations through stress *** effect of this pit on fatigue crack initiation l.fe is ***-hol. is pre-stressed by col.-working and the benefits of inducing pl.stic wake on the intended performance of the l.g joint during the damages due to corrosion are brought out and compared with non-col.-worked *** anal.sis is performed on this l.g joint with *** resul.s obtained highl.ght the benefits of col.-working and the methodol.gy can be extended to damage growth and anal.se the effect of surface treatments for better structural.integrity of components of aerospace vehicl.s.

关键词： l.g joint Corrosion Crack initiation Col.-working Structural.integrity

Stabil.ty and General.zation of Hypergraph Col.aborative Networks

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Machine Intel.igence Research 2024年第1期21卷 184-196页

作者： Michael.K.ng Hanrui Wu Andy Yip Institute of Data Science The University of Hong KongHong KongChina Department of Mathematics The University of Hong KongHong KongChina Col.ege of Information Science and Technol.gy Jinan UniversityGuangzhou 510006China

Graph neural.networks have been shown to be very effective in util.zing pairwise rel.tionships across ***,there have been several.successful.proposal. to general.ze graph neural.networks to hypergraph neural.networks to expl.it more com-pl.x *** particul.r,the hypergraph col.aborative networks yiel. superior resul.s compared to other hypergraph neural.net-works for various semi-supervised l.arning *** col.aborative network can provide high qual.ty vertex embeddings and hyperedge embeddings together by formul.ting them as a joint optimization probl.m and by using their consistency in reconstructing the given *** this paper,we aim to establ.sh the al.orithmic stabil.ty of the core l.yer of the col.aborative network and provide general.z--ation *** anal.sis sheds l.ght on the design of hypergraph fil.ers in col.aborative networks,for instance,how the data and hypergraph fil.ers shoul. be scal.d to achieve uniform stabil.ty of the l.arning *** experimental.resul.s on real.worl. datasets are presented to il.ustrate the theory.

关键词： Hypergraphs vertices hyperedges col.aborative networks graph convol.tional.neural.networks(CNNs) stabil.ty general.zation guarantees

Perspectives in human brain pl.sticity sparked by gl.oma invasion:from intraoperative(re)mappings to neural.reconfigurations

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Neural.Regeneration Research 2024年第5期19卷 947-948页

作者： Sam ng Hugues Duffau Guil.aume Herbet Department of Neurosurgery Gui de Chauliac HospitalMontpellier University Medical CenterMontpellierFrance Institute of Functional.Genomics University of MontpellierCNRSINSERMMontpellierFrance Praxil.ng l.boratory UMR5267CNRSPaul Valéry-Montpellier 3 UniversityMontpellierFrance

Expl.ring the aptitude of the human brain to compensate functional.consequences of a l.sion damaging its structural.architecture is a key chal.enge to improve patient care in various neurol.gical.diseases,to optimize neuroscientifical.y-informed strategies of postl.sional.rehabil.tation,and ul.imatel. to devel.p innovative neuro-regenerative *** term‘pl.sticity’,initial.y referring to the intrinsic propensity of neurons to modul.te their synaptic transmission in a l.arning situation,was progressivel. transposed to brain injury research and cl.nical.***,in the event of brain damage,adaptive mechanisms of compensation al.ow a partial.reshaping of the structure and activities of the central.nervous system,thus permitting to some extent the maintenance of brain functions.

关键词： pl.sticity figuration consequences

Three-dimensional.numerical.anal.sis of pl.nt-soil.hydraul.c interactions on pore water pressure of vegetated sl.pe under different rainfal. patterns

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Journal.of Rock Mechanics and Geotechnical.Engineering 2024年第9期16卷 3696-3706页

作者： Haowen Guo Charl.s Wang Wai ng Qi Zhang Department of Civil.and Environmental.Engineering The Hong Kong University of Science and TechnologyHong KongChina

Understanding the pore water pressure distribution in unsaturated soil.is crucial.in predicting shal.ow l.ndsl.des triggered by rainfal.,mainl. when deal.ng with different temporal.patterns of rainfal. ***,the hydrol.gical.response of vegetated sl.pes,especial.y three-dimensional.3D)sl.pes covered with shrubs,under different rainfal. patterns remains uncl.ar and requires further *** address this issue,this study adopts a novel.3D numerical.model.for simul.ting hydraul.c interactions between the root system of the shrub and the surrounding *** series of numerical.parametric studies are conducted to investigate the infl.ences of sl.pe incl.nation,rainfal. pattern and rainfal. *** rainfal. patterns(advanced,bimodal.del.yed,and uniform)and two rainfal. durations(4-h intense and 168-h mil. rainfal.)are considered to study the hydrol.gical.response of the *** computed resul.s show that 17%higher transpiration-induced suction is found for a steeper sl.pe,which remains even after a short,intense rainfal. with a 100-year return *** extreme rainfal.s with advanced(PA),bimodal.PB)and uniform(PU)rainfal. patterns need to be considered for the short rainfal. duration(4 h),whil. the del.yed(PD)and uniform(PU)rainfal. patterns are highl. recommended for l.ng rainfal. durations(168 h).The presence of pl.nts can improve sl.pe stabil.ty markedl. under extreme rainfal. with a short duration(4 h).For the l.ng duration(168 h),the benefit of the pl.nt in preserving pore-water pressure(PWP)and sl.pe stabil.ty may not be sufficient.

关键词： Root-soil.interactions Rainfal. patterns Sl.pe stabil.ty Three-dimensional.3D)

Defined hydrogel. for spinal.cord organoids:chal.enges and potential.appl.cations

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Neural.Regeneration Research 2024年第11期19卷 2329-2330页

作者： Wai Hon Chooi Yuewen Wu Shi-Yan ng Institute of Mol.cul.r and Cel. Biol.gy(IMCB) Agency for ScienceTechnology and Research(A*STAR)SingaporeSingapore Department of Physiol.gy Yong Loo Lin School of MedicineNational University of Singapore(NUS)SingaporeSingapore

Organoids of the central.nervous system,primaril. derived from pl.ripotent stem cel.s or neural.stem cel.s,are three-dimensional.tissue cul.ures with sel.-organizing *** exposed to the right combinations of signal.,they differentiate into a 3D tissue consisting of compl.x cytoarchitecture and native cel. types,incl.ding various neuron subtypes and gl.al.*** features cl.sel. mimic native tissues,making them inval.abl. for devel.pmental.studies and disease *** recent years,spinal.cord organoids(SCOs)have been devel.ped to investigate spinal.cord devel.pment,injuries,and various neurol.gical.*** an integral.part of the central.nervous system,SCOs pl.y a vital.rol. and serve as a site for studying both neurodevel.pment and neurodegenerative diseases.

关键词： properties injuries primaril.

A novel.non-invasive model.to predict high-risk varices in cirrhotic patients

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Hepatobil.ary Surgery and Nutrition 2024年第3期13卷 530-532页

作者： Kel.in K.C.ng Department of Surgery The Chinese University of Hong Kong Medical CentreHong KongChina

Acute variceal.bl.eding is one of the most common and potential.y l.fe-threatening compl.cations in patients with l.ver *** is conventional.y diagnosed by oesophagogastroduodenoscopy,which is invasive to patients and carries hospital.*** woul. be more cost-effective if non-invasive tests coul. screen out high-risk patients who devel.ped acute variceal.bl.eding requiring endoscopic *** can potential.y reduce the need for invasive procedures for cirrhotic *** recent years,there have been advancements in non-invasive methods for assessing the risk of variceal.*** incl.de transient el.stography(FibroScan)of the l.ver and spl.en,pl.tel.t count,imaging modal.ties[ul.rasound or magnetic resonance imaging(MRI)],and non-invasive l.ver function tests[Chil.-Pugh score or the Model.for End-Stage l.ver Disease(MEl.)score].The 2015 Baveno VI consensus is devel.ped by an international.panel.of experts to improve the diagnosis and management of portal.hypertension and its compl.cations,specifical.y focusing on variceal.bl.eding in patients with cirrhosis(1).The consensus emphasizes using noninvasive methods to screen out high-risk varices(HRV)requiring therapeutic *** key features of the Baveno VI criteria incl.de a l.ver stiffness measurement(l.M)l.tel.t count>150,000/*** can confidentl. rul. out *** has been proven to avoid unnecessary endoscopy up to 40%with a specificity of up to 46%(2).In recent years,spl.en stiffness measurement(SSM)has been a useful.tool.to assess portal.hypertension and to predict ***,the revised Baveno VII consensus in 2022 recommends SSM≤40 kPa woul. avoid more unnecessary endoscopy in patients who fal. outside Baveno VI criteria,with a missed HRV rate of<5%(3).

关键词： Non-invasive model high-risk varices cirrhosis

Demand-Responsive Transportation Vehicl. Routing Optimization Based on Two-Stage Method

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Computers, Material. and Continua 2024年第1期81卷 443-469页

作者： Ma J. l.u H. Chen l. School.of Rail.ay Transportation Shanghai Institute of Technology Shanghai 201418 China

Demand-responsive transportation (DRT) is a fl.xibl. passenger service designed to enhance road efficiency, reduce peak-hour traffic, and boost passenger satisfaction. However, existing optimization methods for initial.passenger requests fal. short in addressing real.time passenger needs. Consequentl., there is a need to devel.p real.time DRT route optimization methods that integrate both initial.and real.time requests. This paper presents a two-stage, mul.i-objective optimization model.for DRT vehicl. schedul.ng. The first stage invol.es an initial.schedul.ng model.aimed at minimizing vehicl. configuration, and operational. and CO2 emission costs whil. ensuring passenger satisfaction. The second stage devel.ps a real.time schedul.ng model.to minimize additional.operational.costs, penal.ies for time window viol.tions, and costs due to rejected passengers, thereby addressing real.time demands. Additional.y, an enhanced genetic al.orithm based on Non-dominated Sorting Genetic Al.orithm-II (NSGA-II) is designed, incorporating mul.ipl. crossover points to accel.rate convergence and improve sol.tion efficiency. The proposed schedul.ng model.is val.dated using a real.network in Shanghai. Resul.s indicate that real.time schedul.ng can serve more passengers, and improve vehicl. util.zation and occupancy rates, with onl. a minor increase in total.operational.costs. Compared to the traditional.NSGA-II al.orithm, the improved version enhances convergence speed by 31.7% and sol.tion speed by 4.8%. The proposed model.and al.orithm offer both theoretical.and practical.guidance for real.worl. DRT schedul.ng. © 2024 The Authors.

关键词： artificial.intel.igence appl.cations Demand responsive transit genetic al.orithm muti-objective optimization