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Tracking SARS-CoV-2 Omicron diverse spike gene mutations identifies multiple inter-variant recombination events

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Signal Transduction and Targeted Therapy 2022年第5期7卷 1808-1816页

作者： Junxian Ou Wendong Lan Xiaowei Wu tie Zhao Biyan Duan Peipei Yang Yi Ren Lulu Quan Wei Zhao Donald Seto James Chodosh Zhen luo Jianguo Wu Qiwei Zhang Guangdong Provincial Key Laboratory of Virology Institute of Medical MicrobiologyJinan University510632 GuangzhouChina BSL-3 Laboratory(Guangdong) Guangdong Provincial Key Laboratory of Tropical Disease ResearchSchool of Public HealthSouthern Medical University510515 GuangzhouChina Bioinformatics and Computational Biology Program School of Systems BiologyGeorge Mason UniversityManassasVA 20110USA Department of Ophthalmology Howe Laboratory Massachusetts Eye and EarHarvard Medical SchoolBostonMA 02114USA Foshan Institute of Medical Microbiology 528315 FoshanChina

The current pandemic of COVID-19 is fueled by more infectious emergent Omicron *** concerns of emergent variants include possible recombinants,as genome recombination is an important evolutionary mechanism for the emergence and re-emergence of human viral *** this study,we identified diverse recombination events between two Omicron major subvariants(BA.1 and BA.2)and other variants of concern(VOCs)and variants of interest(VOIs),suggesting that co-infection and subsequent genome recombination play important roles in the ongoing evolution of *** scanning high-quality completed Omicron spike gene sequences.

关键词： subsequent diverse recombination

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数控端面外圆磨床成形砂轮的修整方法

新技术新工艺 2012年第11期 4-6页

作者：陈智平谭弘瑞王清标郑波罗铁国家高效磨削中心湖南海捷精密工业有限公司湖南长沙410205

介绍一种不带斜轴功能数控系统的数控端面外圆磨床,运用宏程序对X轴(砂轮架)倾斜角度的三角函数计算与插补控制,实现对其成形砂轮进行修整的方法。为了更好地加工轴类零件的端面,且保证能安全地磨削加工砂轮,数控端面外圆磨床的砂轮架... 详细信息

介绍一种不带斜轴功能数控系统的数控端面外圆磨床,运用宏程序对X轴(砂轮架)倾斜角度的三角函数计算与插补控制,实现对其成形砂轮进行修整的方法。为了更好地加工轴类零件的端面,且保证能安全地磨削加工砂轮,数控端面外圆磨床的砂轮架与工作台的角度应为60°,使砂轮斜切入磨削加工。在成形砂轮修整时,由于X轴与Z轴并非垂直,而是成60°,因此,需再对修整程序进行三角函数的计算和程序插补控制,使Z轴跟随X轴自动插补,将砂轮修整出理想的轮廓状态。

关键词：端面外圆磨床砂轮修整插补法数控机床

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降低绵白糖中5-羟甲基糠醛含量的研究

中国甜菜糖业 2010年第3期 1-3页

作者：李琳秦文信董爱军洛铁男马立明哈尔滨工业大学食品科学与工程学院哈尔滨150090

研究了绵白糖生产用转化糖浆制备过程中影响5-羟甲基糠醛（5-HMF）形成、蔗糖转化率以及糖浆色值的因素，并通过正交试验，优化出酸法水解蔗糖生产转化糖浆的工艺条件，即糖浆锤度为75°B，pH值1．5，温度75℃，反应时间60min。在优化... 详细信息

研究了绵白糖生产用转化糖浆制备过程中影响5-羟甲基糠醛（5-HMF）形成、蔗糖转化率以及糖浆色值的因素，并通过正交试验，优化出酸法水解蔗糖生产转化糖浆的工艺条件，即糖浆锤度为75°B，pH值1．5，温度75℃，反应时间60min。在优化条件下每百克转化糖浆含有3．02mg5-HMF，糖浆色值为93．9IU，蔗糖转化率达到91．5％。

关键词： 5-羟甲基糠醛转化糖浆绵白糖蔗糖

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甜菜制糖工业废水综合治理

中国甜菜糖业 2009年第2期 27-31页

作者：李琳洛铁男董爱军秦文信马立明哈尔滨工业大学食品科学与工程学院黑龙江哈尔滨150090 哈尔滨工业大学食品科学与工程学院黑龙江哈尔滨150090 哈尔滨工业大学食品科学与工程学院黑龙江哈尔滨150090 哈尔滨工业大学食品科学与工程学院黑龙江哈尔滨150090 哈尔滨工业大学食品科学与工程学院黑龙江哈尔滨150090

耗水量大和废水量大且有机质含量高是甜菜制糖的特点.耗水量与工艺有关,采用节水工艺可减少新水用量,与此同时废水排出量也减少.同时探讨了甜菜糖厂废水处理工艺.

关键词：水的有效使用环境甜菜制糖废水

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关于事业单位国有资产管理的思考

唐山学院学报 2005年第1期18卷 79-80页

作者：罗铁山李传勇张智新张文志唐山学院国有资产管理处河北唐山063000

事业单位国有资产的管理,是保证事业单位发展的重要基础工作。文章分析了目前事业单位国有资产管理中存在的一些问题,并提出了解决的办法。

关键词：事业单位国有资产管理发展问题办法保证重要基础

PTM： A Topic Model for the Inferring of the Penalty

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Journal of Computer Science & Technology 2018年第4期33卷 756-767页

作者： tie-Ke He Hao Lian Ze-Min Qin Zhen-Yu Chen Bin luo Software Institute Nanjing University Nanjing 210093 China National Key Laboratory for Novel Software Technology Nanjing University Nanjing 210093 China

Deciding the penalty of a law case has always been a complex process, which may involve with much coordination. Despite the judicial study based on the rules and conditions, artificial intelligence and machine learning has rarely been used to study the problem of penalty inferring, leaving the large amount of law cases as well as various factors among them untouched. This paper aims to incorporate the state-of-the-art artificial intelligence methods to exploit to what extent this problem can be alleviated. We first analyze 145 000 law cases and observe that there are two sorts of labels, temporal labels and spatial labels, which have unique characteristics. Temporal labels and spatial labels tend to converge towards the final penalty, on condition that the cases are of the same category. In light of this, we propose a latent-class probabilistic generative model, namely Penalty Topic Model （PTM）, to infer the topic of law cases, and the temporal and spatial patterns of topics embedded in the case judgment. Then, the learnt knowledge is utilized to automatically cluster all cases accordingly in a unified way. We conduct extensive experiments to evaluate the performance of the proposed PTM on a real large-scale dataset of law cases. The experimental results show the superiority of our proposed PTM.

关键词： penalty inferring topic model convolutional neural network support vector machine

Assessing remotely sensed and reanalysis products in characterizing surface soil moisture in the Mongolian Plateau

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International Journal of Digital Earth 2021年第10期14卷 1255-1272页

作者： Min luo Chula Sa Fanhao Meng Yongchao Duan tie Liu Yuhai Bao College of Geographical Science Inner Mongolia Normal UniversityHohhotPeople’s Republic of China Inner Mongolia Key Laboratory of Remote Sensing and Geographic Information Systems Inner Mongolia Normal UniversityHohhotPeople’s Republic of China Binjiang College Nanjing University of Information Science&TechnologyWuxiPeople’s Republic of China State Key Laboratory of Desert and Oasis Ecology Xinjiang Institute of Ecology and GeographyChinese Academy of SciencesUrumqiPeople’s Republic of China

Soil moisture(SM)plays a crucial role in the dynamics of coupled atmosphere,water,energy,and carbon *** this study,the spatiotemporal distribution and variations of SM in the Mongolian Plateau were investigated for the period of 1982-2018 based on four gridded SM *** the observed SM from 33 monitoring stations as a reference,the reliability of these four gridded products was validated,and the three-cornered hat(TCH)method was also applied to evaluate their *** results indicated that all these four products underestimated the SM in this region at different *** ERA-Interim SM performed much better than other three products,with a higher R of 0.53 and lower ubRMSE of 0.0378 m^(3)·m^(−3).Except for ECV,the surface SM exhibited a decreasing trend at−0.0004 to−0.0008 m^(3)·m^(−3)/decade in the warm season(from April to October)over the past 37 *** greatest decreases in SM occurred in the summer *** change plays a more important role in explaining the variations of SM than temperature reported by partial correlation *** results of this study will benefit our understanding of the climate change effects and the protection of the ecological systems in this region.

关键词： Soil moisture Mongolian Plateau uncertainty gridded products

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同时应用内乳动脉和桡动脉行冠状动脉搭桥术

大连医科大学学报 2006年第4期28卷 312-314页

作者：赵鲁宁卞晓明敖定椿毕健骆铁波大连医科大学第一临床学院心外科辽宁大连116011

[目的]介绍同时应用左内乳动脉和桡动脉移植物行冠状动脉搭桥的早期效果和临床经验。[方法]同时应用左内乳动脉和桡动脉行冠状动脉搭桥手术21例。常规体外循环下搭桥18例,非体外下搭桥3例。平均每例搭桥(4.21±0.98)支,搭动脉桥2.6支。... 详细信息

[目的]介绍同时应用左内乳动脉和桡动脉移植物行冠状动脉搭桥的早期效果和临床经验。[方法]同时应用左内乳动脉和桡动脉行冠状动脉搭桥手术21例。常规体外循环下搭桥18例,非体外下搭桥3例。平均每例搭桥(4.21±0.98)支,搭动脉桥2.6支。[结果]全组无手术死亡。随诊未发现心绞痛复发,除1例心衰外,无其他心脏事件发生,无心电图缺血表现发生。无前臂缺血、功能障碍等并发症发生。[结论]内乳动脉和桡动脉搭桥的近期效果显著。

关键词：冠状动脉搭桥内乳动脉桡动脉

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中医诊疗信息数据元构建初探

湖南中医药大学学报 2013年第1期33卷 69-71页

作者：韦昌法黄惠勇罗铁清占艳晏峻峰湖南中医药大学管理与信息工程学院湖南长沙410208 湖南中医药大学中医诊断研究所湖南长沙410208

简述了数据元的概念并进行实例说明,阐述了研究中医信息数据元标准的重要性,以中医问诊中的问汗为例,探讨如何构建中医诊疗信息数据元,提出了中医问汗信息数据元目录及相应的值域代码表,为构建中医信息数据元标准提供一个示范案例。

关键词：中医诊疗信息数据元